PL2326651T3 - Analogi buprenorfiny - Google Patents

Analogi buprenorfiny

Info

Publication number
PL2326651T3
PL2326651T3 PL09789036T PL09789036T PL2326651T3 PL 2326651 T3 PL2326651 T3 PL 2326651T3 PL 09789036 T PL09789036 T PL 09789036T PL 09789036 T PL09789036 T PL 09789036T PL 2326651 T3 PL2326651 T3 PL 2326651T3
Authority
PL
Poland
Prior art keywords
buprenorphine analogs
buprenorphine
analogs
Prior art date
Application number
PL09789036T
Other languages
English (en)
Inventor
Donald J Kyle
R Richard Goehring
Marian E Fundytus
Original Assignee
Purdue Pharma Lp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Pharma Lp filed Critical Purdue Pharma Lp
Publication of PL2326651T3 publication Critical patent/PL2326651T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/09—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems
    • C07D489/10—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14
    • C07D489/12—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14 the bridge containing only two carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
PL09789036T 2008-07-30 2009-07-30 Analogi buprenorfiny PL2326651T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8476408P 2008-07-30 2008-07-30
US22611909P 2009-07-16 2009-07-16
PCT/US2009/004391 WO2010014229A1 (en) 2008-07-30 2009-07-30 Buprenorphine analogs
EP09789036.2A EP2326651B1 (en) 2008-07-30 2009-07-30 Buprenorphine analogs

Publications (1)

Publication Number Publication Date
PL2326651T3 true PL2326651T3 (pl) 2014-05-30

Family

ID=41119539

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09789036T PL2326651T3 (pl) 2008-07-30 2009-07-30 Analogi buprenorfiny

Country Status (25)

Country Link
US (1) US8530494B2 (pl)
EP (2) EP2703404A1 (pl)
JP (2) JP5525524B2 (pl)
KR (1) KR101343395B1 (pl)
CN (2) CN102112479B (pl)
AU (1) AU2009277095B2 (pl)
CA (1) CA2731939C (pl)
CO (1) CO6341635A2 (pl)
DK (1) DK2326651T3 (pl)
ES (1) ES2449222T3 (pl)
HK (1) HK1158622A1 (pl)
HR (1) HRP20140182T1 (pl)
IL (1) IL210391A0 (pl)
ME (1) ME01665B (pl)
MX (1) MX2011001268A (pl)
NZ (1) NZ590650A (pl)
PL (1) PL2326651T3 (pl)
PT (1) PT2326651E (pl)
RS (1) RS53154B (pl)
RU (2) RU2520222C2 (pl)
SI (1) SI2326651T1 (pl)
SM (1) SMT201400023B (pl)
UA (1) UA104004C2 (pl)
WO (1) WO2010014229A1 (pl)
ZA (1) ZA201100188B (pl)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2619212B1 (en) * 2010-09-21 2016-01-06 Purdue Pharma L.P. Buprenorphine analogs as opioid receptor agonists and/or antagonists
FR2975912B1 (fr) 2011-05-30 2013-06-14 Flamel Tech Sa Composition a liberation controlee de buprenorphine
EP2788358B1 (en) 2011-12-08 2018-08-29 Purdue Pharma LP Quaternized buprenorphine analogs
EP3333156A3 (en) 2012-11-09 2018-09-26 Purdue Pharma L.P. Benzomorphan analogs and the use thereof
JP6317755B2 (ja) * 2012-12-07 2018-04-25 パーデュー、ファーマ、リミテッド、パートナーシップ オピオイド受容体モジュレーターとしてのブプレノルフィン類似体
ES2631197T3 (es) 2012-12-14 2017-08-29 Purdue Pharma Lp Análogos de piridonamorfinano y actividad biológica sobre los receptores opiodes
ES2621305T3 (es) 2012-12-14 2017-07-03 Purdue Pharma Lp Morfinanos espirocíclicos y su uso
JP6159417B2 (ja) * 2012-12-28 2017-07-05 パーデュー、ファーマ、リミテッド、パートナーシップ 置換モルフィナンおよびその使用
JP6182620B2 (ja) 2013-01-31 2017-08-16 パーデュー、ファーマ、リミテッド、パートナーシップ ベンゾモルファン類似体およびその使用
US8969358B2 (en) 2013-03-15 2015-03-03 Purdue Pharma L.P. Buprenorphine analogs
WO2015097548A1 (en) * 2013-12-26 2015-07-02 Purdue Pharma L.P. 7-beta-alkyl analogs of orvinols
US9340542B2 (en) 2013-12-26 2016-05-17 Purdue Pharma L.P. Propellane-based compounds and the use thereof
WO2015100092A2 (en) * 2013-12-26 2015-07-02 Purdue Pharma L.P. 7-beta analogs of orvinols
EP3087079B1 (en) 2013-12-26 2019-04-03 Purdue Pharma LP Opioid receptor modulating oxabicyclo[2.2.2]octane morphinans
CN106414408A (zh) 2013-12-26 2017-02-15 普渡制药公司 缩合环吗啡喃和其用途
EP3087073B1 (en) 2013-12-26 2018-07-04 Purdue Pharma LP 10-substituted morphinan hydantoins
WO2015099863A1 (en) 2013-12-27 2015-07-02 Purdue Pharma L.P. 6-substituted and 7-substituted morphinan analogs and the use thereof
WO2015183780A1 (en) 2014-05-27 2015-12-03 Purdue Pharma L.P. Spirocyclic morphinans and use thereof
EP3154972A4 (en) 2014-06-13 2017-11-22 Purdue Pharma L.P. Azamophinan derivatives and use thereof
TW201607923A (zh) 2014-07-15 2016-03-01 歌林達有限公司 被取代之氮螺環（４．５）癸烷衍生物
MA41125A (fr) 2014-12-05 2017-10-10 Purdue Pharma Lp Dérivés de 6.7-cyclomorphinane et leur utilisation
WO2018125716A1 (en) 2017-01-02 2018-07-05 Purdue Pharma L.P. Morphinan derivatives and use thereof

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CN1939920B (zh) * 2005-09-29 2011-08-31 中国人民解放军军事医学科学院毒物药物研究所 东罂粟碱类化合物及其医药用途

Also Published As

Publication number Publication date
PT2326651E (pt) 2014-02-12
DK2326651T3 (da) 2014-01-20
NZ590650A (en) 2013-01-25
CN102112479B (zh) 2014-10-29
CA2731939C (en) 2017-05-23
CN103450206A (zh) 2013-12-18
ES2449222T3 (es) 2014-03-18
RU2013106944A (ru) 2014-08-27
RS53154B (en) 2014-06-30
US8530494B2 (en) 2013-09-10
WO2010014229A1 (en) 2010-02-04
AU2009277095A1 (en) 2010-02-04
UA104004C2 (uk) 2013-12-25
SI2326651T1 (sl) 2014-03-31
SMT201400023B (it) 2014-05-07
HK1158622A1 (en) 2012-07-20
JP2012506839A (ja) 2012-03-22
CA2731939A1 (en) 2010-02-04
US20110136846A1 (en) 2011-06-09
RU2011107440A (ru) 2012-09-10
HRP20140182T1 (hr) 2014-04-11
EP2326651A1 (en) 2011-06-01
JP2014208640A (ja) 2014-11-06
AU2009277095B2 (en) 2012-09-06
IL210391A0 (en) 2011-03-31
JP5525524B2 (ja) 2014-06-18
KR101343395B1 (ko) 2013-12-19
MX2011001268A (es) 2011-07-29
EP2326651B1 (en) 2013-11-27
ME01665B (me) 2014-09-20
CN102112479A (zh) 2011-06-29
KR20110036859A (ko) 2011-04-11
CO6341635A2 (es) 2011-11-21
RU2520222C2 (ru) 2014-06-20
ZA201100188B (en) 2011-09-28
EP2703404A1 (en) 2014-03-05

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