PL2214701T3 - Kompozycje i sposoby wzmacniania odpowiedzi odpornościowych na Eimeria - Google Patents

Kompozycje i sposoby wzmacniania odpowiedzi odpornościowych na Eimeria

Info

Publication number
PL2214701T3
PL2214701T3 PL08843740T PL08843740T PL2214701T3 PL 2214701 T3 PL2214701 T3 PL 2214701T3 PL 08843740 T PL08843740 T PL 08843740T PL 08843740 T PL08843740 T PL 08843740T PL 2214701 T3 PL2214701 T3 PL 2214701T3
Authority
PL
Poland
Prior art keywords
eimeria
compositions
methods
immune responses
enhancing immune
Prior art date
Application number
PL08843740T
Other languages
English (en)
Polish (pl)
Inventor
Walter Bottje
Billy Hargis
Luc Berghman
Young Min Kwon
Kimberly Cole
Mandy Cox
Sherryll Layton
Saeed El-Ashram
John Barta
Guillermo Tellez
Original Assignee
The Board Of Trustees Of The University Of Arkansas
The Texas A&M University System
University Of Guelph
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Board Of Trustees Of The University Of Arkansas, The Texas A&M University System, University Of Guelph filed Critical The Board Of Trustees Of The University Of Arkansas
Publication of PL2214701T3 publication Critical patent/PL2214701T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/455—Eimeria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL08843740T 2007-11-01 2008-11-03 Kompozycje i sposoby wzmacniania odpowiedzi odpornościowych na Eimeria PL2214701T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US98461207P 2007-11-01 2007-11-01

Publications (1)

Publication Number Publication Date
PL2214701T3 true PL2214701T3 (pl) 2017-01-31

Family

ID=40591796

Family Applications (2)

Application Number Title Priority Date Filing Date
PL08843740T PL2214701T3 (pl) 2007-11-01 2008-11-03 Kompozycje i sposoby wzmacniania odpowiedzi odpornościowych na Eimeria
PL16175274T PL3097926T3 (pl) 2007-11-01 2008-11-03 Kompozycje i sposoby wzmacniania odpowiedzi odpornościowych na Eimeria

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL16175274T PL3097926T3 (pl) 2007-11-01 2008-11-03 Kompozycje i sposoby wzmacniania odpowiedzi odpornościowych na Eimeria

Country Status (14)

Country Link
US (3) US8956849B2 (OSRAM)
EP (2) EP3097926B1 (OSRAM)
JP (1) JP5480812B2 (OSRAM)
CN (2) CN101969990B (OSRAM)
AU (1) AU2008318357B2 (OSRAM)
BR (1) BRPI0819229B1 (OSRAM)
CA (3) CA3051748C (OSRAM)
DK (2) DK2214701T3 (OSRAM)
ES (2) ES2599905T3 (OSRAM)
HU (2) HUE047164T2 (OSRAM)
NZ (2) NZ585777A (OSRAM)
PL (2) PL2214701T3 (OSRAM)
PT (2) PT3097926T (OSRAM)
WO (1) WO2009059298A2 (OSRAM)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2520026T3 (es) * 2006-09-18 2014-11-11 The Board Of Trustees Of The University Of Arkansas Composiciones y métodos para potenciar respuestas inmunitarias
US20080124355A1 (en) 2006-09-22 2008-05-29 David Gordon Bermudes Live bacterial vaccines for viral infection prophylaxis or treatment
NZ585776A (en) 2007-10-30 2012-07-27 Univ Arkansas Compositions and methods of enhancing immune responses to flagellated bacterium
CA3051748C (en) * 2007-11-01 2022-07-12 The Board Of Trustees Of The University Of Arkansas Compositions and methods of enhancing immune responses to eimeria
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
PL2525817T3 (pl) 2010-01-21 2018-01-31 Univ Arkansas Wektory szczepionkowe i sposoby wzmacniania odpowiedzi immunologicznych
EA030793B1 (ru) 2010-06-09 2018-09-28 Дзе Борд Оф Трастиз Оф Дзе Юниверсити Оф Арканзас Рекомбинантный вакцинный вектор против инфекции campylobacter и способы усиления иммунного ответа на campylobacter и повышения устойчивости к инфекции campylobacter
AU2013203641B2 (en) * 2011-04-13 2014-08-21 Epizyme, Inc. Aryl-or heteroaryl-substituted benzene compounds
WO2013123412A1 (en) * 2012-02-17 2013-08-22 Children's Medical Center Corporation Conformation-stabilized trap antigens
JP6532407B2 (ja) 2013-02-14 2019-06-19 ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ アーカンソー アイメリアに対する免疫応答を強化するか又はアイメリア感染症を制限する組成物及び方法
CN105142653B (zh) 2013-03-15 2019-11-15 阿肯色大学评议会 增强对肠病原体免疫应答的组合物和方法
CA2981409A1 (en) 2015-05-08 2016-11-17 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
SG11201809686SA (en) 2016-05-03 2018-11-29 Univ Arkansas Yeast vaccine vector including immunostimulatory and antigenic polypeptides and methods of using the same
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
CN110468069B (zh) * 2019-08-19 2020-11-06 中国水产科学研究院长江水产研究所 一种干酪乳杆菌yfi-5及其在抗鲤疱疹病毒ii型中的应用
CN113304254A (zh) * 2021-06-07 2021-08-27 吉林大学 一种微小隐孢子虫Cp15重组侵入型乳酸菌活载体疫苗

Family Cites Families (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2099841C (en) 1991-03-05 2003-02-25 Ian G. Charles Expression of recombinant proteins in attenuated bacteria
US5961974A (en) * 1991-10-25 1999-10-05 Immunex Corporation Monoclonal antibodies to CD40 ligand, pharmaceutical composition comprising the same and hybridomas producing the same
US5716805A (en) * 1991-10-25 1998-02-10 Immunex Corporation Methods of preparing soluble, oligomeric proteins
US5981724A (en) 1991-10-25 1999-11-09 Immunex Corporation DNA encoding CD40 ligand, a cytokine that binds CD40
WO1993008207A1 (en) 1991-10-25 1993-04-29 Immunex Corporation Novel cytokine
US7405270B2 (en) 1991-10-25 2008-07-29 Immunex Corporation CD40-Ligand lacking native-pattern glycosylation
US5962406A (en) 1991-10-25 1999-10-05 Immunex Corporation Recombinant soluble CD40 ligand polypeptide and pharmaceutical composition containing the same
US5540926A (en) * 1992-09-04 1996-07-30 Bristol-Myers Squibb Company Soluble and its use in B cell stimulation
DE69322092T2 (de) 1992-09-04 1999-07-15 University Of Saskatchewan, Saskatoon Neue bakterielle impfstoffe unter verwendung von impfstämmen von pathogenen bakterien
JP4242447B2 (ja) * 1993-01-22 2009-03-25 イミュネックス・コーポレーション Ｃｄ４０リガンド遺伝子の突然変異の検出および治療
AU1059095A (en) 1993-11-24 1995-06-13 Australian National University, The Treatment of viral disease with cd40l peptide
MX9605088A (es) * 1994-04-28 1997-08-30 Boehringer Ingelheim Pharma Metodos para proliferar y diferenciar celulas b y sus usos.
JP3657271B2 (ja) 1995-03-01 2005-06-08 イミュネックス・コーポレーション 病原性または日和見感染性生物に感染した哺乳動物の治療のための組成物
IL122174A (en) 1995-06-07 2004-07-25 Immunex Corp Dna encoding a cd40l mutein and a cd40l polypeptide encoded by said dna
US6479258B1 (en) 1995-12-07 2002-11-12 Diversa Corporation Non-stochastic generation of genetic vaccines
US6713279B1 (en) 1995-12-07 2004-03-30 Diversa Corporation Non-stochastic generation of genetic vaccines and enzymes
US6306387B1 (en) 1997-05-29 2001-10-23 The Research Foundation Of State University Of New York Antigen delivery system
US20030045492A1 (en) 1997-08-13 2003-03-06 Tang De-Chu C. Vaccination by topical application of recombinant vectors
US6969609B1 (en) 1998-12-09 2005-11-29 The United States Of America As Represented By The Department Of Health And Human Serivces Recombinant vector expressing multiple costimulatory molecules and uses thereof
CA2223225A1 (en) 1997-11-28 1999-05-28 Canadian Red Cross Society Method for inhibiting in vivo immune response
IL136731A0 (en) 1997-12-19 2001-06-14 Immunex Corp Method for reducing susceptibility to hiv infection
GB9806449D0 (en) 1998-03-25 1998-05-27 Peptide Therapeutics Ltd Attenuated bacteria useful in vaccines
US6190669B1 (en) 1998-05-13 2001-02-20 University Of Maryland, Baltimore Attenuated mutants of salmonella which constitutively express the Vi antigen
ATE486940T1 (de) 1998-09-04 2010-11-15 Emergent Product Dev Uk Ltd Abgeschwächte salmonella sp12 mutante als antigen-träger.
US7300774B1 (en) 1999-12-09 2007-11-27 The Regents Of The University Of California Multimeric fusion proteins of the TNF superfamily ligands
EP1067194A1 (en) 1999-04-16 2001-01-10 F. Hoffmann-La Roche Ag Vectors containing a gene coding for CD40 and/or CD40L under the control of a cytokine-inducible promoter which is a human acute phase amyloid A gene promoter. Methods for their production and uses thereof
WO2000063395A1 (en) 1999-04-16 2000-10-26 F. Hoffmann-La Roche Ag Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof
US7803765B2 (en) * 1999-05-05 2010-09-28 Phylogica Limited Methods of constructing biodiverse gene fragment libraries and biological modulators isolated therefrom
WO2001026608A2 (en) 1999-10-14 2001-04-19 Ledbetter Jeffrey A Dna vaccines encoding antigen linked to a domain that binds cd40
DK1112747T3 (da) 1999-12-28 2004-10-25 Akzo Nobel Nv Salmonellavaccine, som ikke inducerer antistoffer mod flagellin eller flageller
WO2001056602A2 (en) 2000-02-02 2001-08-09 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Cd40 ligand adjuvant for respiratory syncytial virus
ES2244617T3 (es) 2000-03-17 2005-12-16 Pharmacia & Upjohn Co Llc Vacunas a base de salmonelas en las cuales los genes ssa han sido inactivados.
GB0015426D0 (en) 2000-06-24 2000-08-16 Univ Southampton Method for generating soluble highly multimeric proteins
WO2002000232A2 (en) 2000-06-26 2002-01-03 Maxygen, Inc. Methods and compositions for developing spore display systems for medicinal and industrial applications
AU2002221780A1 (en) 2000-10-31 2002-05-15 F.Hoffmann-La Roche Ag Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof
US6855493B2 (en) * 2000-11-28 2005-02-15 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
EP2107110A3 (en) 2001-05-15 2011-10-26 Ortho-McNeil Pharmaceutical, Inc. Ex-vivo priming for generating cytotoxic T lymphocytes specific for non-tumor antigens to treat autoimmune and allergic disease
WO2003004684A2 (en) 2001-07-06 2003-01-16 David Witcombe NUCLEIC ACIDS ENCODING A RECOMBINANT 250 kDa ANTIGEN FROM SPOROZOITES/MEROZOITES OF EIMERIA MAXIMA AND THEIR USES
ZA200400479B (en) * 2001-07-06 2006-05-31 Abic Biolog Lab Teva Nucleic acids encoding recombinant 56 a 82 KDA antigens from gametocytes of Eimeria maxima and their use
ITMI20011986A1 (it) 2001-09-25 2003-03-25 San Raffaele Centro Fond Metodo e composizione per l'attivazione di cellule presentanti l'antigene
US7378089B2 (en) 2001-10-02 2008-05-27 The Board Of Trustees Of The Leland Stanford Junior University Gene therapy for the prevention of autoimmune disease
US7238499B2 (en) * 2001-12-21 2007-07-03 Immunex Corporation Trimeric macrophage scavenger receptor fusion proteins and encoding nucleic acids
US6929798B2 (en) * 2002-02-13 2005-08-16 Immunology Laboratories, Inc. Compositions and methods for treatment of microbial infections
US6923958B2 (en) 2002-03-02 2005-08-02 The Scripps Research Institute DNA vaccines encoding CEA and a CD40 ligand and methods of use thereof
WO2003096812A1 (en) 2002-04-15 2003-11-27 Washington University Regulated attenuation of live vaccines to enhance cross protective immunogenicity
US7495090B2 (en) 2002-05-23 2009-02-24 The Regents Of The University Of California Nucleic acids encoding chimeric CD154 polypeptides
US20060014248A1 (en) 2003-01-06 2006-01-19 Xencor, Inc. TNF super family members with altered immunogenicity
US20050181994A1 (en) 2003-01-06 2005-08-18 Xencor, Inc. Novel variants of CD40L protein
US7754209B2 (en) 2003-07-26 2010-07-13 Trubion Pharmaceuticals Binding constructs and methods for use thereof
WO2005035570A2 (en) 2003-10-10 2005-04-21 Xencor, Inc. Variants of cd40l protein
US8828957B2 (en) 2003-12-11 2014-09-09 Microvax, Llc Methods for generating immunity to antigen
EP1720905A2 (en) 2003-12-11 2006-11-15 Sidney Kimmel Cancer Center Methods for generating immunity to antigen
WO2005113598A2 (en) 2004-05-21 2005-12-01 Xencor, Inc. Tnf super family members with altered immunogenicity
WO2006042177A2 (en) 2004-10-07 2006-04-20 Argos Therapeutics, Inc. Mature dendritic cell compositions and methods for culturing same
US8513008B2 (en) 2004-10-07 2013-08-20 Argos Therapeutics, Inc. Mature dendritic cell compositions and methods for culturing same
WO2006105972A1 (en) 2005-04-07 2006-10-12 Universite Libre De Bruxelles Transgenic organism expressing cd40l and uses thereof
US20060286074A1 (en) 2005-05-31 2006-12-21 Yucheng Tang Methods for immunotherapy of cancer
RU2431499C2 (ru) 2005-10-07 2011-10-20 Пройекто Де Биомедисина Сима, С.Л. Иммуностимулирующая комбинация для профилактики и лечения гепатита с
WO2007056266A2 (en) 2005-11-07 2007-05-18 Sidney Kimmel Cancer Center Cd40 ligand fusion protein vaccine
DE102005054643B3 (de) 2005-11-10 2007-02-15 Assa Abloy Sicherheitstechnik Gmbh Schließzylinder
WO2007054658A1 (en) 2005-11-14 2007-05-18 King's College London Control of immune responses
CU23576A1 (es) * 2006-02-28 2010-09-30 Ct Ingenieria Genetica Biotech Antígenos vacunales quiméricos contra el virus de la influenza aviar
WO2007103048A2 (en) 2006-03-01 2007-09-13 Regents Of The University Of Colorado Tlr agonist (flagellin)/cd40 agonist/antigen protein and dna conjugates and use thereof for inducing synergistic enhancement in immunity
US8802419B2 (en) 2006-03-02 2014-08-12 University Of Massachusetts Modified pathogens for use as vaccines
FR2898905B1 (fr) * 2006-03-24 2008-05-09 Rhodia Recherches & Tech Composition polyisocyanate a proprietes anti-chocs ameliorees
US20090246220A1 (en) * 2006-08-28 2009-10-01 Ertl Hildegund C J Constructs for enhancing immune responses
ES2520026T3 (es) 2006-09-18 2014-11-11 The Board Of Trustees Of The University Of Arkansas Composiciones y métodos para potenciar respuestas inmunitarias
WO2008109825A2 (en) 2007-03-08 2008-09-12 Mayo Foundation For Medical Education And Research Inducing immune-mediated tumor cell death
CN101024076B (zh) * 2007-03-29 2010-08-18 中国农业大学 球虫的新用途
EP3072903B1 (en) * 2007-07-10 2017-10-25 Apogenix AG Tnf superfamily collectin fusion proteins
NZ585776A (en) * 2007-10-30 2012-07-27 Univ Arkansas Compositions and methods of enhancing immune responses to flagellated bacterium
CA3051748C (en) 2007-11-01 2022-07-12 The Board Of Trustees Of The University Of Arkansas Compositions and methods of enhancing immune responses to eimeria
EP3103875A1 (en) * 2008-07-21 2016-12-14 Apogenix AG Tnfsf single chain molecules
US8316310B2 (en) 2008-08-05 2012-11-20 International Business Machines Corporation System and method for human identification proof for use in virtual environments
PT2184229E (pt) * 2008-11-11 2012-12-20 Agustawestland Spa Rotor de helicóptero
US20100150958A1 (en) * 2008-12-15 2010-06-17 Vectogen Pty Ltd. Methods and Compositions for Use of a Coccidiosis Vaccine
PL2525817T3 (pl) * 2010-01-21 2018-01-31 Univ Arkansas Wektory szczepionkowe i sposoby wzmacniania odpowiedzi immunologicznych
SG10201707813YA (en) * 2011-10-11 2017-11-29 Medimmune Llc Cd40l-specific tn3-derived scaffolds and methods of use thereof
WO2014043215A1 (en) * 2012-09-11 2014-03-20 The Texas A&M University System Bi-specifc diabodies for masking and targeting vaccines
PL2911676T3 (pl) * 2012-10-29 2020-12-28 The Board Of Trustees Of The University Of Arkansas Nowe adiuwanty śluzówkowe oraz systemy dostarczania
JP6532407B2 (ja) * 2013-02-14 2019-06-19 ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ アーカンソー アイメリアに対する免疫応答を強化するか又はアイメリア感染症を制限する組成物及び方法
CN105142653B (zh) * 2013-03-15 2019-11-15 阿肯色大学评议会 增强对肠病原体免疫应答的组合物和方法
SG11201609965XA (en) * 2014-06-05 2016-12-29 Univ Arkansas Antibody guided vaccines and methods of use for generation of rapid mature immune responses
WO2016054225A1 (en) * 2014-09-30 2016-04-07 Stc.Unm Plasmid delivery in the treatment of cancer and other disease states
AU2017244108B2 (en) * 2016-03-29 2021-03-18 University Of Southern California Chimeric antigen receptors targeting cancer
US10519243B2 (en) * 2016-05-27 2019-12-31 Abbvie Biotherapeutics Inc. Anti-CD40 antibodies
US10576167B2 (en) * 2016-08-17 2020-03-03 Factor Bioscience Inc. Nucleic acid products and methods of administration thereof

Also Published As

Publication number Publication date
WO2009059298A3 (en) 2009-09-24
BRPI0819229B1 (pt) 2019-01-22
EP2214701A2 (en) 2010-08-11
JP5480812B2 (ja) 2014-04-23
ES2761693T3 (es) 2020-05-20
DK3097926T3 (da) 2019-12-16
PT3097926T (pt) 2020-01-08
NZ585777A (en) 2012-09-28
PL3097926T3 (pl) 2020-04-30
US8956849B2 (en) 2015-02-17
US10016493B2 (en) 2018-07-10
WO2009059298A2 (en) 2009-05-07
HK1146575A1 (zh) 2011-06-24
CN103893747A (zh) 2014-07-02
BRPI0819229A2 (pt) 2015-05-05
DK2214701T3 (en) 2016-12-12
HUE047164T2 (hu) 2020-04-28
HUE030655T2 (en) 2017-05-29
CA3156538C (en) 2023-12-12
AU2008318357B2 (en) 2015-01-22
NZ601880A (en) 2013-12-20
ES2599905T3 (es) 2017-02-06
EP2214701B1 (en) 2016-08-03
US10842858B2 (en) 2020-11-24
EP2214701A4 (en) 2011-06-01
WO2009059298A8 (en) 2010-08-05
CA3156538A1 (en) 2009-05-07
AU2008318357A2 (en) 2010-06-24
CA2704422C (en) 2019-09-24
US20150216954A1 (en) 2015-08-06
CA2704422A1 (en) 2009-05-07
US20180333474A1 (en) 2018-11-22
PT2214701T (pt) 2016-11-02
CN103893747B (zh) 2016-01-06
EP3097926A1 (en) 2016-11-30
EP3097926B1 (en) 2019-10-02
JP2011503003A (ja) 2011-01-27
CA3051748C (en) 2022-07-12
CA3051748A1 (en) 2009-05-07
US20110111015A1 (en) 2011-05-12
CN101969990B (zh) 2014-07-09
CN101969990A (zh) 2011-02-09
AU2008318357A1 (en) 2009-05-07

Similar Documents

Publication Publication Date Title
PL2214701T3 (pl) Kompozycje i sposoby wzmacniania odpowiedzi odpornościowych na Eimeria
EP2066339A4 (en) COMPOSITIONS AND METHODS FOR IMPROVING IMMUNE RESPONSES
EP2334185A4 (en) COMPOSITIONS AND METHODS FOR USE OF (R) -PRAMIPEXOL
IL208946A0 (en) Immunomodulating compositions and methods of use thereof
SMT201800444T1 (it) Metodi e composizioni per indurre una risposta immunitaria contro egfrviii
EP2231665A4 (en) NEW COMPOSITIONS AND METHODS OF USE
ZA201101641B (en) Use of mtor inhibitors to enhance t cell immune responses
HRP20160902T1 (hr) Pripravci i postupci uporabe forbolskih estera
IL220715A0 (en) Nutritive compositions and methods of using same
IL201364A0 (en) Gas-effusing compositions and methods of making and using same
ZA201003964B (en) Compositions for and methods of enhancing the immune response to antigens
GB0812890D0 (en) Compositions and methods of making compositions
IL247929B (en) Stable compositions of 595–sns and methods for their preparation
GB0801479D0 (en) Improvements to methods of in field analysis
EP2349293A4 (en) CINNAMALDEHYDE-ALLICIN COMPOSITIONS AND METHODS OF USE
IL207827A0 (en) Apoaequorin-containing compositions and methods of using same
ZA200908300B (en) Natural honey-containing compositions and method of preparation
PL2328402T3 (pl) Sposoby i kompozycje do wydłużenia okresu przechowywania owoców
ZA201100114B (en) Nutritive compositions and methods of using same
EP2381950A4 (en) COMPOSITIONS AND METHOD FOR THEIR USE
SI2401400T1 (sl) Metode in sestavki za ocenjevanje kroničnih avtoimunskih bolezni
AU2009900926A0 (en) Compositions and methods for enhancing immune responses