PL2191006T3 - Sposoby oznaczania aktywności enzymatycznej alfa-L-duronidazy - Google Patents
Sposoby oznaczania aktywności enzymatycznej alfa-L-duronidazyInfo
- Publication number
- PL2191006T3 PL2191006T3 PL08827775T PL08827775T PL2191006T3 PL 2191006 T3 PL2191006 T3 PL 2191006T3 PL 08827775 T PL08827775 T PL 08827775T PL 08827775 T PL08827775 T PL 08827775T PL 2191006 T3 PL2191006 T3 PL 2191006T3
- Authority
- PL
- Poland
- Prior art keywords
- methods
- enzymatic activity
- iduronidase enzymatic
- assaying
- alpha
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/18—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted otherwise than in position 3 or 7
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01076—L-Iduronidase (3.2.1.76)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95664407P | 2007-08-17 | 2007-08-17 | |
| EP08827775A EP2191006B1 (en) | 2007-08-17 | 2008-08-18 | Methods for assaying alpha-l-iduronidase enzymatic activity |
| PCT/US2008/073516 WO2009026252A1 (en) | 2007-08-17 | 2008-08-18 | Methods for assaying alpha-l-iduronidase enzymatic activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2191006T3 true PL2191006T3 (pl) | 2013-05-31 |
Family
ID=39929712
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08827775T PL2191006T3 (pl) | 2007-08-17 | 2008-08-18 | Sposoby oznaczania aktywności enzymatycznej alfa-L-duronidazy |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US8088745B2 (pl) |
| EP (1) | EP2191006B1 (pl) |
| JP (1) | JP2010536347A (pl) |
| ES (1) | ES2396797T3 (pl) |
| PL (1) | PL2191006T3 (pl) |
| PT (1) | PT2191006E (pl) |
| WO (1) | WO2009026252A1 (pl) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2396797T3 (es) | 2007-08-17 | 2013-02-27 | University Of Washington | Procedimientos de ensayo de la actividad enzimática alfa-L-iduronidasa |
| WO2012027612A1 (en) * | 2010-08-25 | 2012-03-01 | Michael Gelb | Mass spectrometric compositions and methods for lysosomal storage disease screening |
| WO2013070953A1 (en) | 2011-11-08 | 2013-05-16 | University Of Washington | Lysosomal enzyme assay methods and compositions |
| JP6128808B2 (ja) * | 2011-11-15 | 2017-05-17 | 栄研化学株式会社 | 酵素活性の検出、測定方法およびこれを利用したキット |
| CN103487414A (zh) * | 2012-06-14 | 2014-01-01 | 北京和信非凡生物技术有限公司 | 一种α-L-艾杜糖醛酸酶活性检测方法、底物和试剂 |
| JP6585052B2 (ja) | 2013-09-05 | 2019-10-02 | ユニヴァーシティ・オブ・ワシントン・スルー・イッツ・センター・フォー・コマーシャリゼーション | Ｍｐｓ ｉ、ｉｉ、ｉｉｉａ、ｉｉｉｂ、ｉｖａ、ｖｉ、およびｖｉｉをスクリーニングするための試薬および方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0603266B1 (en) * | 1991-08-23 | 1999-05-12 | Molecular Probes, Inc. | Use of haloalkyl derivatives of reporter molecules to analyze metabolic activity in cells |
| US5773236A (en) * | 1997-04-25 | 1998-06-30 | Molecule Probes, Inc. | Assay for glutathiane transferase using polyhaloaryl-substituted reporter molecules |
| US5998593A (en) * | 1998-03-10 | 1999-12-07 | Abbott Laboratories | Fluorescent enzyme substrates |
| US6670194B1 (en) * | 1998-08-25 | 2003-12-30 | University Of Washington | Rapid quantitative analysis of proteins or protein function in complex mixtures |
| WO2006102958A1 (en) * | 2005-03-29 | 2006-10-05 | Newron Pharmaceuticals S.P.A. | Substituted aminoalkyl- and amidoalkyl-benzopyran derivatives |
| ES2396797T3 (es) * | 2007-08-17 | 2013-02-27 | University Of Washington | Procedimientos de ensayo de la actividad enzimática alfa-L-iduronidasa |
-
2008
- 2008-08-18 ES ES08827775T patent/ES2396797T3/es active Active
- 2008-08-18 PT PT88277751T patent/PT2191006E/pt unknown
- 2008-08-18 PL PL08827775T patent/PL2191006T3/pl unknown
- 2008-08-18 WO PCT/US2008/073516 patent/WO2009026252A1/en active Application Filing
- 2008-08-18 JP JP2010521227A patent/JP2010536347A/ja active Pending
- 2008-08-18 EP EP08827775A patent/EP2191006B1/en active Active
-
2010
- 2010-02-17 US US12/706,794 patent/US8088745B2/en active Active
-
2011
- 2011-11-09 US US13/292,371 patent/US9012663B2/en active Active
-
2015
- 2015-03-16 US US14/659,483 patent/US9790536B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20150353985A1 (en) | 2015-12-10 |
| US8088745B2 (en) | 2012-01-03 |
| US20120052519A1 (en) | 2012-03-01 |
| JP2010536347A (ja) | 2010-12-02 |
| PT2191006E (pt) | 2013-01-04 |
| US9012663B2 (en) | 2015-04-21 |
| EP2191006B1 (en) | 2012-11-21 |
| US9790536B2 (en) | 2017-10-17 |
| US20100209951A1 (en) | 2010-08-19 |
| EP2191006A1 (en) | 2010-06-02 |
| ES2396797T3 (es) | 2013-02-27 |
| WO2009026252A1 (en) | 2009-02-26 |
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