PL2188306T3 - Fragmenty powstałe po cięciu immunoglobuliny jako wskaźniki choroby oraz kompozycje do ich wykrywania i wiązania - Google Patents

Fragmenty powstałe po cięciu immunoglobuliny jako wskaźniki choroby oraz kompozycje do ich wykrywania i wiązania

Info

Publication number
PL2188306T3
PL2188306T3 PL08782610T PL08782610T PL2188306T3 PL 2188306 T3 PL2188306 T3 PL 2188306T3 PL 08782610 T PL08782610 T PL 08782610T PL 08782610 T PL08782610 T PL 08782610T PL 2188306 T3 PL2188306 T3 PL 2188306T3
Authority
PL
Poland
Prior art keywords
binding
compositions
detecting
cleavage fragments
disease indicators
Prior art date
Application number
PL08782610T
Other languages
English (en)
Inventor
Robert Jordan
Diane D. Petrone
Mary Ryan
Original Assignee
Janssen Biotech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech, Inc. filed Critical Janssen Biotech, Inc.
Publication of PL2188306T3 publication Critical patent/PL2188306T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065Purification, fragmentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734Complement-dependent cytotoxicity [CDC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
PL08782610T 2007-08-10 2008-08-04 Fragmenty powstałe po cięciu immunoglobuliny jako wskaźniki choroby oraz kompozycje do ich wykrywania i wiązania PL2188306T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US95516207P 2007-08-10 2007-08-10

Publications (1)

Publication Number Publication Date
PL2188306T3 true PL2188306T3 (pl) 2017-01-31

Family

ID=40351057

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08782610T PL2188306T3 (pl) 2007-08-10 2008-08-04 Fragmenty powstałe po cięciu immunoglobuliny jako wskaźniki choroby oraz kompozycje do ich wykrywania i wiązania

Country Status (20)

Country Link
US (1) US20090155280A1 (pl)
EP (1) EP2188306B1 (pl)
JP (2) JP5530356B2 (pl)
KR (2) KR20150059813A (pl)
CN (2) CN101889021B (pl)
AU (1) AU2008287128B2 (pl)
BR (1) BRPI0814355A2 (pl)
CA (1) CA2696011A1 (pl)
DK (1) DK2188306T3 (pl)
EA (1) EA025220B1 (pl)
ES (1) ES2593791T3 (pl)
HU (1) HUE029649T2 (pl)
IL (1) IL203544A (pl)
MX (1) MX2010001616A (pl)
NZ (1) NZ582916A (pl)
PL (1) PL2188306T3 (pl)
PT (1) PT2188306T (pl)
SG (1) SG183701A1 (pl)
WO (1) WO2009023457A1 (pl)
ZA (1) ZA201001689B (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8501907B2 (en) * 2007-08-10 2013-08-06 Janssen Biotech, Inc. Immunoglobulin cleavage fragments as disease indicators and compositions for detecting and binding such
CA3031851C (en) 2009-10-23 2020-07-07 Amgen British Columbia Anti-gcc antibody molecules and related compositions and methods
BR112012010252A2 (pt) 2009-10-29 2016-12-06 Janssen Biotech Inc variantes de glicosilação de anticorpo
US8041225B2 (en) * 2009-12-21 2011-10-18 General Electric Company Contactless infrared data transmission for wind turbines
US20120269834A1 (en) * 2010-11-19 2012-10-25 Robert Jordan Immunoglobulin cleavage fragment vaccine compositions
KR101820558B1 (ko) 2010-12-23 2018-02-28 유리타 아. 게. 넓은 영역에 나노 구조체를 생산하기 위한 시스템 및 방법
JP6012624B2 (ja) 2010-12-23 2016-10-25 ヤンセン バイオテツク,インコーポレーテツド 活性プロテアーゼ耐性抗体Fc突然変異体
KR102046435B1 (ko) * 2012-04-27 2019-11-19 밀레니엄 파머슈티컬스 인코퍼레이티드 항-gcc 항체 분자 및 gcc-표적화 치료법에 대한 감수성을 평가하기 위한 그 용도
US10654933B2 (en) * 2013-12-27 2020-05-19 Chugai Seiyaku Kabushiki Kaisha Method for purifying antibody having low isoelectric point
ES2861600T3 (es) 2014-04-04 2021-10-06 Mayo Found Medical Education & Res Isotipaje de inmunoglobulinas usando masa molecular precisa
US11209439B2 (en) 2015-09-24 2021-12-28 Mayo Foundation For Medical Education And Research Identification of immunoglobulin free light chains by mass spectrometry
WO2018049001A1 (en) 2016-09-07 2018-03-15 Mayo Foundation For Medical Education And Research Identification and monitoring of cleaved immunoglobulins by molecular mass
WO2019055632A1 (en) 2017-09-13 2019-03-21 Mayo Foundation For Medical Education And Research IDENTIFICATION AND MONITORING OF IMMUNOGLOBULIN CHAINS J
US11946937B2 (en) 2017-09-13 2024-04-02 Mayo Foundation For Medical Education And Research Identification and monitoring of apoptosis inhibitor of macrophage
TW201925233A (zh) 2017-12-07 2019-07-01 日商中外製藥股份有限公司 抗體、用於在樣品中偵測或捕捉多肽的組成物以及在樣品中偵測或捕捉多肽的方法
US20210325380A1 (en) * 2020-04-20 2021-10-21 EnLiSense, LLC Disease diagnostics using a multi-configurable sensing array

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2162863T3 (es) * 1993-04-29 2002-01-16 Unilever Nv Produccion de anticuerpos o fragmentos (funcionalizados) de los mismos derivados de inmunoglobulinas de cadena pesada de camelidae.
AUPM322393A0 (en) * 1993-12-24 1994-01-27 Austin Research Institute, The Mucin carbohydrate compounds and their use in immunotherapy
US7129331B2 (en) * 2000-05-31 2006-10-31 Pestka Biomedical Laboratories, Inc. Phosphorylated polypeptides and uses related thereto
GB0130228D0 (en) * 2001-12-18 2002-02-06 Hansa Medica Ab Protein

Also Published As

Publication number Publication date
AU2008287128A1 (en) 2009-02-19
AU2008287128B2 (en) 2013-07-18
EP2188306B1 (en) 2016-06-29
CN103497254A (zh) 2014-01-08
JP5530356B2 (ja) 2014-06-25
CN103497254B (zh) 2016-12-28
CA2696011A1 (en) 2009-02-19
EP2188306A4 (en) 2011-03-02
BRPI0814355A2 (pt) 2015-01-27
HUE029649T2 (en) 2017-02-28
US20090155280A1 (en) 2009-06-18
CN101889021B (zh) 2016-06-08
ES2593791T3 (es) 2016-12-13
EP2188306A1 (en) 2010-05-26
WO2009023457A1 (en) 2009-02-19
NZ582916A (en) 2012-08-31
KR101588276B1 (ko) 2016-01-26
IL203544A (en) 2015-07-30
KR20100059850A (ko) 2010-06-04
ZA201001689B (en) 2011-06-29
CN101889021A (zh) 2010-11-17
JP2010536037A (ja) 2010-11-25
MX2010001616A (es) 2010-03-15
KR20150059813A (ko) 2015-06-02
SG183701A1 (en) 2012-09-27
DK2188306T3 (en) 2016-08-22
PT2188306T (pt) 2016-09-13
EA025220B1 (ru) 2016-12-30
JP2014058535A (ja) 2014-04-03
EA201070236A1 (ru) 2010-08-30

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