PL2173868T3 - Rekombinowane preparaty wybranych frakcji bromelainy - Google Patents

Rekombinowane preparaty wybranych frakcji bromelainy

Info

Publication number
PL2173868T3
PL2173868T3 PL08785459T PL08785459T PL2173868T3 PL 2173868 T3 PL2173868 T3 PL 2173868T3 PL 08785459 T PL08785459 T PL 08785459T PL 08785459 T PL08785459 T PL 08785459T PL 2173868 T3 PL2173868 T3 PL 2173868T3
Authority
PL
Poland
Prior art keywords
recombinant preparation
bromelain
fractions
bromelain fractions
recombinant
Prior art date
Application number
PL08785459T
Other languages
English (en)
Inventor
ROLF MüLLER
Nora Luniak
Klaus Eschmann
Original Assignee
Ursapharm Arzneimittel Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ursapharm Arzneimittel Gmbh filed Critical Ursapharm Arzneimittel Gmbh
Publication of PL2173868T3 publication Critical patent/PL2173868T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/63—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Botany (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
PL08785459T 2007-09-14 2008-08-08 Rekombinowane preparaty wybranych frakcji bromelainy PL2173868T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07018125A EP2036978A1 (en) 2007-09-14 2007-09-14 Recombinant preparation of selected bromelain fractions
PCT/EP2008/006564 WO2009033536A1 (en) 2007-09-14 2008-08-08 Recombinant preparation of selected bromelain fractions
EP08785459A EP2173868B1 (en) 2007-09-14 2008-08-08 Recombinant preparation of selected bromelain fractions

Publications (1)

Publication Number Publication Date
PL2173868T3 true PL2173868T3 (pl) 2013-03-29

Family

ID=39144517

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08785459T PL2173868T3 (pl) 2007-09-14 2008-08-08 Rekombinowane preparaty wybranych frakcji bromelainy

Country Status (11)

Country Link
US (1) US8409840B2 (pl)
EP (2) EP2036978A1 (pl)
JP (1) JP2010538622A (pl)
CN (1) CN101889083A (pl)
CA (1) CA2699429A1 (pl)
DK (1) DK2173868T3 (pl)
ES (1) ES2395591T3 (pl)
MX (1) MX2010002769A (pl)
PL (1) PL2173868T3 (pl)
PT (1) PT2173868E (pl)
WO (1) WO2009033536A1 (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL165334A0 (en) 2004-11-22 2006-01-15 Mediwound Ltd Debriding composition from bromelain and methods of producing same
MY190244A (en) * 2009-12-17 2022-04-08 International Islamic Univ Malaysia Method for producing recombinant stem bromelain
AU2013240271A1 (en) 2012-03-26 2014-10-02 Axcella Health Inc. Nutritive fragments, proteins and methods
CA2868522A1 (en) 2012-03-26 2013-10-03 Pronutria, Inc. Charged nutritive proteins and methods
EP2831100A4 (en) 2012-03-26 2016-02-10 Pronutria Inc NUTRIENT PROTEINS AND METHODS
EP2831099B1 (en) 2012-03-26 2020-04-22 Axcella Health Inc. Nutritive fragments, proteins and methods
AU2014324900A1 (en) 2013-09-25 2016-05-19 Axcella Health Inc. Compositions and formulations for prevention and reduction of tumorigenesis, cancer cell proliferation and invasion, and methods of production and use thereof in cancer treatment
KR102376345B1 (ko) 2016-01-31 2022-03-18 메디운드 리미티드 상처 치료용 괴사조직제거 조성물
JP6859158B2 (ja) * 2017-03-31 2021-04-14 第一工業製薬株式会社 ポリウレタン樹脂用ポリオール組成物、ポリウレタン樹脂形成性組成物、複合材料
CN110477100B (zh) * 2019-08-22 2023-11-07 内蒙古蒙牛乳业（集团）股份有限公司 一种两吃型酸奶固体饮料及其制备方法
WO2021255625A1 (en) * 2020-06-16 2021-12-23 Anatara Lifesciences Limited Protease composition

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3658651A (en) * 1970-04-28 1972-04-25 Castle & Cooke Ion exchange treatment of bromelain
US4286064A (en) * 1979-11-05 1981-08-25 Riker Laboratories, Inc. Process for isolating active debriding agent from bromelain
GB9313188D0 (en) * 1993-06-25 1993-08-11 Cortecs Ltd Medical use of enzymes
KR100201008B1 (ko) * 1996-10-09 1999-06-15 박종헌 글루텐 펩타이드를 외인성 고지혈증 및 고콜레스트레롤증 억제에 이용하는 방법
CN1091152C (zh) 1996-12-23 2002-09-18 茂名市茂辉公司化州分公司 菠萝蛋白酶的物理提取方法
WO1998038320A1 (en) * 1997-02-25 1998-09-03 Cortecs (Uk) Limited Component of bromelain
US6803038B1 (en) * 1998-07-15 2004-10-12 Ursapharm Arzneimittel Gmbh Use of bromelaine proteases for inhibiting blood coagulation
GB9819138D0 (en) * 1998-09-02 1998-10-28 Cortecs Uk Ltd Nucleic acids and proteins from pineapple stem
JP2002003362A (ja) * 2000-06-22 2002-01-09 Kyoei Kagaku Kogyo Kk 皮膚外用剤
JP4969741B2 (ja) * 2001-07-26 2012-07-04 株式会社ノエビア 皮膚外用剤
JP4411192B2 (ja) * 2003-12-05 2010-02-10 エフ．ホフマン−ラ ロシュ アーゲー 組換えで発現されるカルボキシペプチダーゼｂおよびその精製
AU2004318207B2 (en) * 2004-03-08 2009-12-17 Syngenta Participations Ag Self-processing plants and plant parts
WO2008021543A2 (en) * 2006-08-17 2008-02-21 Monsanto Technology, Llc Transgenic plants with enhanced agronomic traits

Also Published As

Publication number Publication date
PT2173868E (pt) 2013-01-08
EP2173868A1 (en) 2010-04-14
US20100272659A1 (en) 2010-10-28
EP2173868B1 (en) 2012-10-17
WO2009033536A1 (en) 2009-03-19
EP2036978A1 (en) 2009-03-18
ES2395591T3 (es) 2013-02-13
JP2010538622A (ja) 2010-12-16
CA2699429A1 (en) 2009-03-19
DK2173868T3 (da) 2013-02-18
CN101889083A (zh) 2010-11-17
MX2010002769A (es) 2010-09-07
US8409840B2 (en) 2013-04-02

Similar Documents

Publication Publication Date Title
PL2173868T3 (pl) Rekombinowane preparaty wybranych frakcji bromelainy
IL245994A0 (en) Extended substituted polypeptides and preparations comprising them
IL196004A0 (en) Refolding of recombinant proteins
EP2348049A4 (en) NEW APPLICATION OF AIMP1 POLYPEPTIDE
ZA201109364B (en) Stabilized protein compositions
IL209983A (en) Compounds of proteins and polypeptides with cross-linking
IL194120A0 (en) Stabilized polypeptide compositions
GB0700523D0 (en) The Stabilisation Of Proteins
IL199547A (en) Preparation of romidapsine
ZA200810456B (en) Lyophilized formulations of anti-EGFR antibodies
EP2152304A4 (en) THERAPEUTIC COMPOSITIONS IN NANOEMULSION FORM AND METHOD OF APPLICATION THEREFOR
HK1144823A1 (en) Compositions and methods of using proislet peptides and analogs thereof
IL220386B (en) Preparations for the elimination of cancer tumors and their uses
GB0626021D0 (en) The stabilisation of proteins
IL219470A0 (en) Compositions containing fractalknie-binding proteins and uses thereof
ZA200807964B (en) Stabilized polypeptide compositions
IL198659A (en) Targeted signals and recombinant proteins containing them
EP2270141A4 (en) Lacritin PART PEPTIDE
IL216199A (en) A peptide containing the sequence ednimvtfrnqasr
GB0724953D0 (en) Methods of peptide modification
EP2172550A4 (en) C-TERMINAL-A-AMIDATED RECOMBINANT ENZYME DERIVATIVE
GB0601251D0 (en) Protein solubilisation composition
GB0709037D0 (en) Isolation of proteins
PL380652A1 (pl) Rozcieracz minicząstek
GB0915735D0 (en) Recombinant protein separation