PL2167526T3 - Oczyszczanie czynnika VIII za pomocą żywicy o mieszanej funkcji lub wielofunkcyjnej - Google Patents

Oczyszczanie czynnika VIII za pomocą żywicy o mieszanej funkcji lub wielofunkcyjnej

Info

Publication number
PL2167526T3
PL2167526T3 PL08786090T PL08786090T PL2167526T3 PL 2167526 T3 PL2167526 T3 PL 2167526T3 PL 08786090 T PL08786090 T PL 08786090T PL 08786090 T PL08786090 T PL 08786090T PL 2167526 T3 PL2167526 T3 PL 2167526T3
Authority
PL
Poland
Prior art keywords
purification
factor viii
mixed
mode
multimodal resin
Prior art date
Application number
PL08786090T
Other languages
English (en)
Inventor
Susanne Bang
Lars Thim
Johan Karlsson
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of PL2167526T3 publication Critical patent/PL2167526T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL08786090T 2007-07-11 2008-07-11 Oczyszczanie czynnika VIII za pomocą żywicy o mieszanej funkcji lub wielofunkcyjnej PL2167526T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07112287 2007-07-11
EP08786090A EP2167526B1 (en) 2007-07-11 2008-07-11 Purification of factor viii using a mixed-mode or multimodal resin
PCT/EP2008/059094 WO2009007451A1 (en) 2007-07-11 2008-07-11 Purification of factor viii using a mixed-mode or multimodal resin

Publications (1)

Publication Number Publication Date
PL2167526T3 true PL2167526T3 (pl) 2011-09-30

Family

ID=38472947

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08786090T PL2167526T3 (pl) 2007-07-11 2008-07-11 Oczyszczanie czynnika VIII za pomocą żywicy o mieszanej funkcji lub wielofunkcyjnej

Country Status (15)

Country Link
US (1) US8399620B2 (pl)
EP (1) EP2167526B1 (pl)
JP (1) JP5323072B2 (pl)
KR (1) KR101293504B1 (pl)
CN (1) CN101730707B (pl)
AT (1) ATE503763T1 (pl)
AU (1) AU2008274195B2 (pl)
BR (1) BRPI0814220B8 (pl)
CA (1) CA2692814A1 (pl)
DE (1) DE602008005885D1 (pl)
ES (1) ES2364118T3 (pl)
NL (1) NL300663I2 (pl)
PL (1) PL2167526T3 (pl)
RU (1) RU2493163C2 (pl)
WO (1) WO2009007451A1 (pl)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5619738B2 (ja) * 2008-06-24 2014-11-05 オクタファルマ アクチェンゲゼルシャフト 凝固第viii因子の精製方法
MX2011001624A (es) 2008-08-21 2011-03-28 Octapharma Ag Factor viii y ix humano producido en forma recombinante.
US8945895B2 (en) 2009-07-31 2015-02-03 Baxter International Inc. Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof
US8277649B2 (en) 2009-12-14 2012-10-02 General Electric Company Membranes and associated methods for purification of antibodies
US8974780B2 (en) 2010-02-24 2015-03-10 Zymenex A/S Process for production and purification of recombinant lysosomal alpha-mannosidase
RU2015149979A (ru) 2010-03-30 2019-01-15 Октафарма Аг Способ очистки белка фактора роста
WO2011121020A1 (en) 2010-03-30 2011-10-06 Octapharma Ag A process for purifying vitamin k dependent proteins such as coagulation factor ix
US9422329B2 (en) 2010-11-05 2016-08-23 Hoffmann-La Roche Inc. Optimized method for antibody capturing by mixed mode chromatography
CA2821711C (en) 2010-12-15 2017-10-10 Baxter International Inc. Eluate collection using conductivity gradient
WO2013075740A1 (en) 2011-11-23 2013-05-30 Sanofi Antibody purification method
CN105777862A (zh) 2012-10-24 2016-07-20 建新公司 使用mes和mops作为流动相改性剂从多峰树脂洗脱生物分子
US10188965B2 (en) 2012-12-05 2019-01-29 Csl Behring Gmbh Hydrophobic charge induction chromatographic depletion of a protein from a solution
US20140154233A1 (en) 2012-12-05 2014-06-05 Csl Limited Method of purifying therapeutic proteins
CN103396494B (zh) * 2013-04-27 2015-04-01 江苏省疾病预防控制中心 一种凝血因子ix的单克隆抗体
TWI631132B (zh) 2013-05-06 2018-08-01 賽諾菲公司 用於純化抗體之連續多步驟方法
TW201617360A (zh) * 2014-06-25 2016-05-16 桂格 史考特 布蘭克 用於純化蛋白質之方法及試劑
MX2017000862A (es) 2014-08-04 2017-05-01 Csl Ltd Formulacion de factor viii.
DK3265483T3 (da) 2015-03-06 2020-03-02 CSL Behring Lengnau AG Modificeret von Willebrand-faktor med forbedret halveringstid
GB201506117D0 (en) 2015-04-10 2015-05-27 Ge Healthcare Bio Sciences Ab Method for chromatography
GB201506113D0 (en) 2015-04-10 2015-05-27 Ge Healthcare Bio Sciences Ab Method for chromatography
EP3205665A1 (en) * 2016-02-11 2017-08-16 Octapharma AG Method of separating factor viii from blood products
GB201617240D0 (en) * 2016-10-11 2016-11-23 Profactor Pharma Ltd Purification process
CN111183151B (zh) 2017-06-23 2024-06-07 武田药品工业株式会社 因子viii亚种的纯化
KR20220029733A (ko) 2019-07-04 2022-03-08 체에스엘 베링 렝나우 아게 응고 인자 viii의 시험관내 안정성을 증가시키기 위한 절단된 폰 빌레브란트 인자 (vwf)
JP2023500953A (ja) 2019-11-11 2023-01-11 ツェー・エス・エル・ベーリング・レングナウ・アクチエンゲゼルシャフト 第viii因子に対する寛容を誘導するためのポリペプチド

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9302006D0 (sv) * 1992-10-02 1993-06-11 Kabi Pharmacia Ab Protein formulation
SE9301581D0 (sv) * 1993-05-07 1993-05-07 Kabi Pharmacia Ab Protein formulation
SE503424C2 (sv) * 1994-11-14 1996-06-10 Pharmacia Ab Process för rening av rekombinant koagulationsfaktor VIII
IL157309A0 (en) * 2003-08-07 2004-02-19 Applied Research Systems Method for the purification of a non-immunoglobulin protein
EP1831242B1 (en) * 2004-12-23 2012-09-26 Novo Nordisk Health Care AG Reduction of the content of protein contaminants in compositions comprising a vitamin k-dependent protein of interest
EP1707634A1 (en) 2005-03-29 2006-10-04 Octapharma AG Method for isolation of recombinantly produced proteins
JP5619738B2 (ja) 2008-06-24 2014-11-05 オクタファルマ アクチェンゲゼルシャフト 凝固第viii因子の精製方法

Also Published As

Publication number Publication date
RU2010103528A (ru) 2011-08-20
BRPI0814220B8 (pt) 2021-05-25
AU2008274195A1 (en) 2009-01-15
DE602008005885D1 (de) 2011-05-12
BRPI0814220A2 (pt) 2015-01-06
KR20100051620A (ko) 2010-05-17
AU2008274195B2 (en) 2013-09-05
ES2364118T9 (es) 2014-05-19
JP2010533150A (ja) 2010-10-21
US20100204452A1 (en) 2010-08-12
CN101730707A (zh) 2010-06-09
CA2692814A1 (en) 2009-01-15
KR101293504B1 (ko) 2013-08-07
CN101730707B (zh) 2014-12-17
JP5323072B2 (ja) 2013-10-23
US8399620B2 (en) 2013-03-19
BRPI0814220B1 (pt) 2019-09-17
ATE503763T1 (de) 2011-04-15
RU2493163C2 (ru) 2013-09-20
EP2167526A1 (en) 2010-03-31
NL300663I2 (pl) 2016-09-22
EP2167526B1 (en) 2011-03-30
WO2009007451A1 (en) 2009-01-15
ES2364118T3 (es) 2011-08-25

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