PL2137202T3 - Sposób syntezy IB-MECA - Google Patents

Sposób syntezy IB-MECA

Info

Publication number
PL2137202T3
PL2137202T3 PL08719985T PL08719985T PL2137202T3 PL 2137202 T3 PL2137202 T3 PL 2137202T3 PL 08719985 T PL08719985 T PL 08719985T PL 08719985 T PL08719985 T PL 08719985T PL 2137202 T3 PL2137202 T3 PL 2137202T3
Authority
PL
Poland
Prior art keywords
meca
synthesis
Prior art date
Application number
PL08719985T
Other languages
English (en)
Inventor
Paul Bruzinski
Xuejun Liu
Cameron Gibb
Pedro Hernandez-Abad
Original Assignee
Can-Fite Biopharma Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Can-Fite Biopharma Ltd. filed Critical Can-Fite Biopharma Ltd.
Publication of PL2137202T3 publication Critical patent/PL2137202T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
PL08719985T 2007-03-14 2008-03-13 Sposób syntezy IB-MECA PL2137202T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US90683807P 2007-03-14 2007-03-14
PCT/IL2008/000360 WO2008111082A1 (en) 2007-03-14 2008-03-13 Process for the synthesis of ib-meca
EP08719985.7A EP2137202B1 (en) 2007-03-14 2008-03-13 Process for the synthesis of ib-meca

Publications (1)

Publication Number Publication Date
PL2137202T3 true PL2137202T3 (pl) 2017-12-29

Family

ID=39530638

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08719985T PL2137202T3 (pl) 2007-03-14 2008-03-13 Sposób syntezy IB-MECA

Country Status (10)

Country Link
US (1) US9102698B2 (pl)
EP (1) EP2137202B1 (pl)
JP (1) JP5467872B2 (pl)
CN (1) CN101646685B (pl)
DK (1) DK2137202T3 (pl)
ES (1) ES2641190T3 (pl)
HU (1) HUE034474T2 (pl)
PL (1) PL2137202T3 (pl)
PT (1) PT2137202T (pl)
WO (1) WO2008111082A1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019105388A1 (zh) * 2017-11-29 2019-06-06 苏州科睿思制药有限公司 一种a3腺苷受体激动剂药物的晶型及其制备方法和用途
CN110003211A (zh) * 2019-05-06 2019-07-12 江苏联昇化学有限公司 一种抗癌药物cf-102的合成新工艺

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4930392A (pl) * 1972-07-18 1974-03-18
DE2244328A1 (de) * 1972-09-09 1974-03-21 Boehringer Mannheim Gmbh Neue n(6)-disubstituierte adenosinderivate und verfahren zur herstellung derselben
AU7331094A (en) 1993-07-13 1995-02-13 United States Of America, As Represented By The Secretary, Department Of Health And Human Services, The A3 adenosine receptor agonists
IL127947A0 (en) 1999-01-07 1999-11-30 Can Fite Technologies Ltd Pharmaceutical use of adenosine agonists
CN1259056C (zh) 2001-01-16 2006-06-14 坎-菲特生物药物有限公司 腺苷a3受体激动剂用于抑制病毒复制的用途
ATE371191T1 (de) 2002-10-22 2007-09-15 Can Fite Biopharma Ltd Die verwendung von dem a3 adenosin rezeptor als marker eines krankheitszustandes
US7141553B2 (en) 2002-11-19 2006-11-28 Can-Fite Biopharma Ltd. Israel A3AR agonists for the treatment of inflammatory arthritis
JPWO2004065403A1 (ja) 2003-01-17 2006-05-18 味の素株式会社 ヌクレオシド化合物の製造方法
FI115172B (fi) 2003-07-24 2005-03-15 Filtronic Lk Oy Antennijärjestely ulkoisen laitteen liittämiseksi radiolaitteeseen
PL1699459T3 (pl) 2003-12-29 2007-12-31 Can Fite Biopharma Ltd Sposób leczenia stwardnienia rozsianego
PL1778239T3 (pl) 2004-07-28 2014-01-31 Can Fite Biopharma Ltd Agoniści receptora adenozynowego A3 do leczenia zaburzeń suchego oka w tym zespołu Sjogrena
US7825102B2 (en) 2004-07-28 2010-11-02 Can-Fite Biopharma Ltd. Treatment of dry eye conditions
MX2007005525A (es) 2004-11-08 2007-07-05 Can Fite Biopharma Ltd Tratamiento terapeutico de resorcion ose acelerada.
AU2005310874B2 (en) 2004-12-02 2008-11-27 Can-Fite Biopharma Ltd. Treatment of inflammation
EP1959939B1 (en) 2005-11-30 2012-01-11 Can-Fite Biopharma Ltd. Use of a3 adenosine receptor agonist in osteoarthritis treatment
EP1976494A1 (en) 2006-01-27 2008-10-08 Can-Fite Biopharma Ltd. Adenosine a3 receptor agonists for the treatment of dry eye disorders

Also Published As

Publication number Publication date
HUE034474T2 (en) 2018-02-28
EP2137202A1 (en) 2009-12-30
JP5467872B2 (ja) 2014-04-09
PT2137202T (pt) 2017-10-02
US20100087636A1 (en) 2010-04-08
CN101646685A (zh) 2010-02-10
JP2010521452A (ja) 2010-06-24
ES2641190T3 (es) 2017-11-08
CN101646685B (zh) 2014-12-17
EP2137202B1 (en) 2017-06-21
US9102698B2 (en) 2015-08-11
WO2008111082A1 (en) 2008-09-18
DK2137202T3 (en) 2017-10-02

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PL2137202T3 (pl) Sposób syntezy IB-MECA