PL2126097T3 - Transgeny do supresji genu dominującego i sposoby ich stosowania - Google Patents

Transgeny do supresji genu dominującego i sposoby ich stosowania

Info

Publication number
PL2126097T3
PL2126097T3 PL08743883T PL08743883T PL2126097T3 PL 2126097 T3 PL2126097 T3 PL 2126097T3 PL 08743883 T PL08743883 T PL 08743883T PL 08743883 T PL08743883 T PL 08743883T PL 2126097 T3 PL2126097 T3 PL 2126097T3
Authority
PL
Poland
Prior art keywords
methods
same
gene suppression
dominant gene
transgenes
Prior art date
Application number
PL08743883T
Other languages
English (en)
Inventor
Andrew M Cigan
Tim W Fox
Howard P Hershey
Erica Unger
Yongzhong Wu
Original Assignee
Pioneer Hi Bred Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pioneer Hi Bred Int filed Critical Pioneer Hi Bred Int
Publication of PL2126097T3 publication Critical patent/PL2126097T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8287—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for fertility modification, e.g. apomixis
    • C12N15/8289—Male sterility
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8287—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for fertility modification, e.g. apomixis
    • C12N15/829—Female sterility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5097—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving plant cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Botany (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL08743883T 2007-03-14 2008-03-14 Transgeny do supresji genu dominującego i sposoby ich stosowania PL2126097T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/685,956 US20070169227A1 (en) 2003-12-16 2007-03-14 Dominant Gene Suppression Transgenes and Methods of Using Same
PCT/US2008/056989 WO2008112970A2 (en) 2007-03-14 2008-03-14 Dominant gene suppression transgenes and methods of using same
EP08743883A EP2126097B1 (en) 2007-03-14 2008-03-14 Dominant gene suppression transgenes and methods of using same

Publications (1)

Publication Number Publication Date
PL2126097T3 true PL2126097T3 (pl) 2013-04-30

Family

ID=39760793

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08743883T PL2126097T3 (pl) 2007-03-14 2008-03-14 Transgeny do supresji genu dominującego i sposoby ich stosowania

Country Status (14)

Country Link
US (4) US20070169227A1 (pl)
EP (1) EP2126097B1 (pl)
CN (1) CN101679998A (pl)
AU (1) AU2008224912B2 (pl)
BR (1) BRPI0808896A2 (pl)
CA (2) CA2821430A1 (pl)
ES (1) ES2396104T3 (pl)
MX (1) MX2009009796A (pl)
MY (1) MY147209A (pl)
PH (1) PH12013500640A1 (pl)
PL (1) PL2126097T3 (pl)
SG (1) SG179478A1 (pl)
WO (1) WO2008112970A2 (pl)
ZA (1) ZA200906478B (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090117255A1 (en) * 2007-09-12 2009-05-07 The Texas A&M University System Wheat Lines And Improved Food Compositions
WO2011057333A1 (en) * 2009-11-11 2011-05-19 La Trobe University Transgenic plant male sterility
EP2339008A1 (en) * 2009-12-23 2011-06-29 Universita' Degli Studi Di Milano Basal transcription factors silencing to induce recoverable male sterility in plants
EP2637780B1 (en) 2010-11-12 2022-02-09 Gen9, Inc. Protein arrays and methods of using and making the same
US20130059296A1 (en) 2011-08-26 2013-03-07 Gen9, Inc. Compositions and Methods For High Fidelity Assembly of Nucleic Acids
US9631203B2 (en) 2012-03-13 2017-04-25 Pioneer Hi-Bred International, Inc. Genetic reduction of male fertility in plants
CA2867377A1 (en) * 2012-03-13 2013-09-19 Pioneer Hi-Bred International, Inc. Genetic reduction of male fertility in plants
MX2014011038A (es) 2012-03-13 2015-06-02 Pioneer Hi Bred Int Reduccion genetica de la fertilidad masculina en plantas.
US9150853B2 (en) 2012-03-21 2015-10-06 Gen9, Inc. Methods for screening proteins using DNA encoded chemical libraries as templates for enzyme catalysis
CA2871505C (en) 2012-04-24 2021-10-12 Gen9, Inc. Methods for sorting nucleic acids and multiplexed preparative in vitro cloning
US9803214B2 (en) * 2013-03-12 2017-10-31 Pioneer Hi-Bred International, Inc. Breeding pair of wheat plants comprising an MS45 promoter inverted repeat that confers male sterility and a construct that restores fertility
US20160017350A1 (en) 2013-03-15 2016-01-21 Pioneer Hi-Bred International, Inc. Compositions and methods of use of acc oxidase polynucleotides and polypeptides
US10117390B2 (en) 2013-09-16 2018-11-06 Xingwang Investment Co., Ltd. Use of genic male sterility gene and mutation thereof in hybridization
BR112021004851A2 (pt) * 2018-09-14 2021-06-08 Pioneer Hi-Bred International, Inc. restauração da fertilidade em plantas
EP4376593A1 (en) * 2021-07-26 2024-06-05 Elsoms Developments Ltd Methods and compositions relating to maintainer lines for male-sterility

Family Cites Families (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3484215D1 (de) 1983-01-17 1991-04-11 Monsanto Co Chimaerische gene geeignet zur expression in pflanzenzellen.
NL8300698A (nl) 1983-02-24 1984-09-17 Univ Leiden Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten.
GB2159173B (en) 1984-05-11 1988-10-12 Ciba Geigy Ag Transformation of hereditary material of plants
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US4918006A (en) 1985-07-01 1990-04-17 E. I. Du Pont De Nemours And Company Gene coding for insecticidal crystal protein
GB8810120D0 (en) 1988-04-28 1988-06-02 Plant Genetic Systems Nv Transgenic nuclear male sterile plants
US5633441A (en) 1989-08-04 1997-05-27 Plant Genetic Systems, N.V. Plants with genetic female sterility
JPH05502370A (ja) 1989-09-13 1993-04-28 エムエル　テクノロジー　ヴェンチャーズ　エル．ピー． 分子量３９ｋＤａの赤痢病原体抗原およびそれに対する遺伝子暗号付与
US5641876A (en) 1990-01-05 1997-06-24 Cornell Research Foundation, Inc. Rice actin gene and promoter
EP0528857B1 (en) 1990-04-26 2002-01-30 Aventis CropScience N.V. New bacillus thuringiensis strain and its gene encoding insecticidal toxin
US5451513A (en) 1990-05-01 1995-09-19 The State University of New Jersey Rutgers Method for stably transforming plastids of multicellular plants
US5478369A (en) * 1990-06-12 1995-12-26 Pioneer Hi-Bred International, Inc. Nucleotide sequences mediating male fertility and method of using same
US5277905A (en) 1991-01-16 1994-01-11 Mycogen Corporation Coleopteran-active bacillus thuringiensis isolate
EP0602064B1 (en) 1991-08-02 1998-12-16 Mycogen Corporation Novel microorganism and insecticide
GB9304200D0 (en) 1993-03-02 1993-04-21 Sandoz Ltd Improvements in or relating to organic compounds
JPH07501701A (ja) 1991-12-04 1995-02-23 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 植物由来の脂肪酸不飽和化酵素遺伝子
WO1993025695A1 (en) 1992-06-12 1993-12-23 Plant Genetic Systems N.V. Maintenance of male-sterile plants
US5750867A (en) * 1992-06-12 1998-05-12 Plant Genetic Systems, N.V. Maintenance of male-sterile plants
ATE398679T1 (de) 1992-07-07 2008-07-15 Japan Tobacco Inc Verfahren zur transformation einer monokotyledon pflanze
ATE147434T1 (de) 1992-07-09 1997-01-15 Pioneer Hi Bred Int Pollen spezifische polygalacturonase gen aus mais
HUT70467A (en) 1992-07-27 1995-10-30 Pioneer Hi Bred Int An improved method of agrobactenium-mediated transformation of cultvred soyhean cells
US5332808A (en) 1992-09-08 1994-07-26 North Carolina State University DNA encoding a ribosome inactivating protein
US5409823A (en) * 1992-09-24 1995-04-25 Ciba-Geigy Corporation Methods for the production of hybrid seed
JP3818540B2 (ja) 1992-11-17 2006-09-06 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 植物由来のミクロソームデルタ−１２脂肪酸デサチュラーゼおよび関連酵素の遺伝子
AU5676394A (en) 1992-11-20 1994-06-22 Agracetus, Inc. Transgenic cotton plants producing heterologous bioplastic
CA2161881C (en) 1993-01-13 2001-03-27 A. Gururaj Rao High lysine derivatives of alpha-hordothionin
ATE193729T1 (de) 1993-02-26 2000-06-15 Calgene Llc Geminivirus-basiertes-genexpressionsystem
US5576198A (en) 1993-12-14 1996-11-19 Calgene, Inc. Controlled expression of transgenic constructs in plant plastids
US5837458A (en) 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5545818A (en) 1994-03-11 1996-08-13 Calgene Inc. Expression of Bacillus thuringiensis cry proteins in plant plastids
US5545817A (en) 1994-03-11 1996-08-13 Calgene, Inc. Enhanced expression in a plant plastid
US5470359A (en) 1994-04-21 1995-11-28 Pioneer Hi-Bred Internation, Inc. Regulatory element conferring tapetum specificity
US5593881A (en) 1994-05-06 1997-01-14 Mycogen Corporation Bacillus thuringiensis delta-endotoxin
US5767373A (en) 1994-06-16 1998-06-16 Novartis Finance Corporation Manipulation of protoporphyrinogen oxidase enzyme activity in eukaryotic organisms
US5792931A (en) 1994-08-12 1998-08-11 Pioneer Hi-Bred International, Inc. Fumonisin detoxification compositions and methods
US5608144A (en) 1994-08-12 1997-03-04 Dna Plant Technology Corp. Plant group 2 promoters and uses thereof
US5631152A (en) 1994-10-26 1997-05-20 Monsanto Company Rapid and efficient regeneration of transgenic plants
BR9408621A (pt) 1994-10-28 1998-07-21 Pioneer Hi Bred Int Sequéncia de nucleotídeo (seq-id no-2) molécula de rna molécula de dna vetor plasmídeo célula de planta processo de mediar fertilidade de planta processo de mediar fertilidade masculina em planta planta com fertilidade masculina intermediada processo para fornecer esterilidade masculina controlável externamente herdável em planta processo para reproduzir planta planta macho controlavelmente estéril processo de produzir semente híbrida e cassete de expressao
US5750868A (en) 1994-12-08 1998-05-12 Pioneer Hi-Bred International, Inc. Reversible nuclear genetic system for male sterility in transgenic plants
US5795753A (en) 1994-12-08 1998-08-18 Pioneer Hi-Bred International Inc. Reversible nuclear genetic system for male sterility in transgenic plants
US5659026A (en) 1995-03-24 1997-08-19 Pioneer Hi-Bred International ALS3 promoter
BR9609200A (pt) 1995-06-02 1999-05-11 Pioneer Hi Bred Int Derivados de alta treonina de alpha-hordotionina
HUP9900878A2 (hu) 1995-06-02 1999-07-28 Pioneer Hi-Bred International, Inc. Alfa-hordotionin nagy metionintartalmú származéka
US6008437A (en) * 1995-06-06 1999-12-28 Plant Genetic Systems Use of anthocyanin genes to maintain male sterile plants
US5737514A (en) 1995-11-29 1998-04-07 Texas Micro, Inc. Remote checkpoint memory system and protocol for fault-tolerant computer system
US5703049A (en) 1996-02-29 1997-12-30 Pioneer Hi-Bred Int'l, Inc. High methionine derivatives of α-hordothionin for pathogen-control
US5850016A (en) 1996-03-20 1998-12-15 Pioneer Hi-Bred International, Inc. Alteration of amino acid compositions in seeds
US6072050A (en) 1996-06-11 2000-06-06 Pioneer Hi-Bred International, Inc. Synthetic promoters
US6232529B1 (en) 1996-11-20 2001-05-15 Pioneer Hi-Bred International, Inc. Methods of producing high-oil seed by modification of starch levels
US6096947A (en) 1997-01-14 2000-08-01 Pioneer Hi-Bred International, Inc. Methods for improving transformation efficiency
GB9710475D0 (en) * 1997-05-21 1997-07-16 Zeneca Ltd Gene silencing
US6037523A (en) * 1997-06-23 2000-03-14 Pioneer Hi-Bred International Male tissue-preferred regulatory region and method of using same
NZ504300A (en) 1997-11-18 2002-06-28 Pioneer Hi Bred Int A method for directional stable transformation of eukaryotic cells using non-identical recombination sites
EP1056864B1 (en) 1998-02-26 2004-10-06 Pioneer Hi-Bred International, Inc. Constitutive maize promoters
JP2002512775A (ja) 1998-03-17 2002-05-08 ノバルティス アクチエンゲゼルシャフト Ｍｌｏタンパク質をコードし、植物に真菌耐性を付与する遺伝子
EP1080197A2 (en) 1998-05-22 2001-03-07 Pioneer Hi-Bred International, Inc. Cell cycle genes, proteins and uses thereof
EP1104469B1 (en) 1998-08-20 2005-11-09 Pioneer Hi-Bred International, Inc. Seed-preferred promoters
AU5788299A (en) 1998-08-28 2000-03-21 Pioneer Hi-Bred International, Inc. Seed-preferred promoters from (end) genes
WO2000015791A1 (en) 1998-09-10 2000-03-23 Pioneer Hi-Bred International, Inc. Ecdysone receptors and methods for their use
US6518487B1 (en) 1998-09-23 2003-02-11 Pioneer Hi-Bred International, Inc. Cyclin D polynucleotides, polypeptides and uses thereof
WO2000055315A1 (en) 1999-03-16 2000-09-21 Pioneer Hi-Bred International, Inc. Sf3 promoter and methods of use
US6429357B1 (en) 1999-05-14 2002-08-06 Dekalb Genetics Corp. Rice actin 2 promoter and intron and methods for use thereof
GB9925459D0 (en) * 1999-10-27 1999-12-29 Plant Bioscience Ltd Gene silencing
HUP0301053A3 (en) * 2000-02-15 2004-10-28 Pioneer Hi Bred Internat Inc D Male tissue-specific regulatory region and method of using same
US7517975B2 (en) * 2000-09-26 2009-04-14 Pioneer Hi-Bred International, Inc. Nucleotide sequences mediating male fertility and method of using same
EP1320618B1 (en) 2000-09-26 2012-03-07 Pioneer Hi-Bred International, Inc. Nucleotide sequences mediating male fertility and method of using same
US6956118B2 (en) 2001-02-08 2005-10-18 Pioneer Hi-Bred International, Inc. Promoter sequences providing male tissue-preferred expression in plants
WO2003057848A2 (en) 2001-12-31 2003-07-17 Yeda Research And Development Co., Ltd A method to maintain a genic male-sterile female parental line of wheat through selfing of the maintainer line
US7074985B2 (en) 2002-02-15 2006-07-11 Pioneer Hi-Bred International, Inc. Development of a stress-responsive promoter from maize
DE10224889A1 (de) 2002-06-04 2003-12-18 Metanomics Gmbh & Co Kgaa Verfahren zur stabilen Expression von Nukleinsäuren in transgenen Pflanzen
EP1527183B1 (de) * 2002-07-26 2008-08-20 BASF Plant Science GmbH Neue selektionsverfahren
US20030175968A1 (en) * 2002-10-30 2003-09-18 Golic Kent G. Gene targeting method
WO2005059121A2 (en) * 2003-12-16 2005-06-30 Pioneer Hi-Bred International, Inc. Dominant gene suppression transgenes and methods of using same

Also Published As

Publication number Publication date
US20110030084A1 (en) 2011-02-03
ES2396104T3 (es) 2013-02-19
US8785722B2 (en) 2014-07-22
SG179478A1 (en) 2012-04-27
CA2821430A1 (en) 2008-09-18
US20140289895A1 (en) 2014-09-25
AU2008224912B2 (en) 2012-06-28
PH12013500640A1 (en) 2016-01-25
CA2680799A1 (en) 2008-09-18
CA2680799C (en) 2013-10-08
ZA200906478B (en) 2010-05-26
MX2009009796A (es) 2009-10-16
WO2008112970A3 (en) 2009-01-15
US20070169227A1 (en) 2007-07-19
EP2126097B1 (en) 2012-09-26
AU2008224912A1 (en) 2008-09-18
WO2008112970A2 (en) 2008-09-18
CN101679998A (zh) 2010-03-24
BRPI0808896A2 (pt) 2014-09-02
EP2126097A2 (en) 2009-12-02
US20180201946A1 (en) 2018-07-19
MY147209A (en) 2012-11-14

Similar Documents

Publication Publication Date Title
ZA200906478B (en) Dominant gene suppression transgenes and methods of using same
HK1147254A1 (en) 5-anilinoimidazopyridines and methods of use 5-
HK1148220A1 (en) Methods of reducing eosinophil levels
HRP20160902T1 (hr) Pripravci i postupci uporabe forbolskih estera
PT2170403E (pt) Composições e métodos para inibição da expressão de genes pró-apoptóticos
EP2334185A4 (en) COMPOSITIONS AND METHODS FOR USE OF (R) -PRAMIPEXOL
HK1149933A1 (en) Diazacarbazoles and methods of use
IL206125A0 (en) Azaindolizines and methods of use
EP2069467A4 (en) SEPARATION COMPOSITIONS AND METHOD FOR THEIR USE
IL209548A0 (en) Diazacarbazoles and methods of use
IL207827A0 (en) Apoaequorin-containing compositions and methods of using same
EP2142672A4 (en) COMPOSITIONS AND METHODS FOR SILENCING GENES
GB2473390B (en) Nutritive compositions and methods of using same
IL201228A0 (en) Methods of gene amplification and expression
AU2008901690A0 (en) Methods of Inducing Photoprotection and DNA Protection
ZA200908464B (en) Methods of reducing eosinophil levels
GB0702107D0 (en) Method and Uses of Compunds