PL2101731T3 - Endoksyfen do zastosowania w leczeniu nowotworu - Google Patents
Endoksyfen do zastosowania w leczeniu nowotworuInfo
- Publication number
- PL2101731T3 PL2101731T3 PL07871563T PL07871563T PL2101731T3 PL 2101731 T3 PL2101731 T3 PL 2101731T3 PL 07871563 T PL07871563 T PL 07871563T PL 07871563 T PL07871563 T PL 07871563T PL 2101731 T3 PL2101731 T3 PL 2101731T3
- Authority
- PL
- Poland
- Prior art keywords
- endoxifen
- cancer
- treatment
- Prior art date
Links
- MHJBZVSGOZTKRH-IZHYLOQSSA-N 4-Hydroxy-N-desmethyltamoxifen Chemical compound C=1C=CC=CC=1C(/CC)=C(C=1C=CC(OCCNC)=CC=1)/C1=CC=C(O)C=C1 MHJBZVSGOZTKRH-IZHYLOQSSA-N 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86042006P | 2006-11-21 | 2006-11-21 | |
| US86078806P | 2006-11-22 | 2006-11-22 | |
| EP07871563.8A EP2101731B1 (en) | 2006-11-21 | 2007-11-21 | Endoxifen for use in the treatment of cancer |
| PCT/US2007/085443 WO2008070463A2 (en) | 2006-11-21 | 2007-11-21 | Endoxifen methods and compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2101731T3 true PL2101731T3 (pl) | 2018-07-31 |
Family
ID=39492975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07871563T PL2101731T3 (pl) | 2006-11-21 | 2007-11-21 | Endoksyfen do zastosowania w leczeniu nowotworu |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9333190B2 (show.php) |
| EP (1) | EP2101731B1 (show.php) |
| JP (1) | JP2010510327A (show.php) |
| CA (1) | CA2669913C (show.php) |
| DK (1) | DK2101731T3 (show.php) |
| ES (1) | ES2665917T3 (show.php) |
| HU (1) | HUE037109T2 (show.php) |
| IN (1) | IN2014MN00139A (show.php) |
| PL (1) | PL2101731T3 (show.php) |
| PT (1) | PT2101731T (show.php) |
| WO (1) | WO2008070463A2 (show.php) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090291134A1 (en) | 2006-11-21 | 2009-11-26 | Jina Pharmaceuticals, Inc. | Endoxifen methods and compositions in the treatment of psychiatric and neurodegenerative diseases |
| PT2101731T (pt) | 2006-11-21 | 2018-04-18 | Jina Pharmaceuticals Inc | Endoxifeno para utilização no tratamento de cancro |
| DK2373305T3 (en) * | 2008-12-11 | 2017-05-15 | Besins Healthcare Lu Sarl | TRANSDERMAL PHARMACEUTICAL COMPOSITIONS INCLUDING A SERM |
| KR102122416B1 (ko) | 2011-04-28 | 2020-06-12 | 온코펩타이드즈 아베 | 세포독성 디펩티드의 동결건조 제제 |
| EP2668945A1 (de) | 2012-06-01 | 2013-12-04 | Bayer Technology Services GmbH | Genotyp- bzw. Phänotyp-basierte Arzeimittelformulierungen |
| US10285946B2 (en) * | 2012-10-26 | 2019-05-14 | Oncopeptides Ab | Lyophilized preparations of melphalan flufenamide |
| AU2016294526A1 (en) * | 2015-07-14 | 2018-02-08 | Atossa Genetics Inc. | Transpapillary methods and compositions for treating breast disorders |
| DE102015222031A1 (de) | 2015-11-10 | 2017-05-11 | Robert Bosch Gesellschaft Für Medizinische Forschung Mbh | Synthese von (Z)-Endoxifenhydrochlorid |
| US20170304232A1 (en) * | 2016-04-20 | 2017-10-26 | Northwestern University | Endoxifen For Local Transdermal Therapy To The Breast |
| US20200215006A1 (en) * | 2017-09-11 | 2020-07-09 | Atossa Therapeutics, Inc. | Topical compositions and methods for treatment |
| IL304863B2 (en) | 2017-09-11 | 2025-08-01 | Atossa Therapeutics Inc | Methods for making and using endoxifen |
| AU2020300624A1 (en) | 2019-07-03 | 2022-02-03 | Atossa Therapeutics, Inc. | Sustained release compositions of endoxifen |
| BR112022020320A2 (pt) | 2020-04-10 | 2022-12-13 | Jina Pharmaceuticals Inc | Método para manter uma concentração terapeuticamente eficaz de endoxifeno para tratamento de um paciente com distúrbio bipolar i |
| CA3185993A1 (en) | 2020-04-10 | 2021-10-14 | Jina Pharmaceuticals, Inc. | Endoxifen for the treatment of bipolar i disorder |
| WO2022197988A1 (en) * | 2021-03-18 | 2022-09-22 | National Taiwan University | Lipid-based nanoparticle delivery system for hydrophilic charged compound |
| IL314075A (en) | 2022-01-12 | 2024-09-01 | Atossa Therapeutics Inc | Compositions of (Z)-endoxifen and methods for their enrichment |
| WO2023211939A1 (en) * | 2022-04-26 | 2023-11-02 | Atossa Therapeutics, Inc. | High dose endoxifen formulations and methods of use |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2817157A1 (de) * | 1978-04-17 | 1979-10-25 | Schering Ag | Verwendung von antioestrogenen und antigonadotrop wirkenden antiandrogenen zur prophylaxe und therapie der prostatahyperplasie |
| SK283026B6 (sk) * | 1994-08-04 | 2003-02-04 | Quadrant Holdings Cambridge Limited | Tuhý časticový prostriedok na terapeutické použitie a spôsob jeho prípravy |
| US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| ATE345682T1 (de) * | 1996-05-01 | 2006-12-15 | Imarx Pharmaceutical Corp | In vitro verfahren zum einbringen von nukleinsäuren in eine zelle |
| US6090407A (en) | 1997-09-23 | 2000-07-18 | Research Development Foundation | Small particle liposome aerosols for delivery of anti-cancer drugs |
| US7968532B2 (en) | 2003-12-15 | 2011-06-28 | Besins Healthcare Luxembourg | Treatment of gynecomastia with 4-hydroxy tamoxifen |
| HUE031951T2 (en) | 2006-10-10 | 2017-08-28 | Jina Pharmaceuticals Inc | Aqueous systems for lipid-based drug compounds; preparations, processes and their use |
| WO2008048194A1 (en) | 2006-10-20 | 2008-04-24 | Yesilogluj Aysegul Yildiz | Use of the protein kinase c inhibitor tamoxifen for the treatment of bipolar disorder |
| JP2010509355A (ja) | 2006-11-06 | 2010-03-25 | ジャイナ ファーマシューティカルズ，インコーポレーテッド | グッグルリン脂質の方法および組成物 |
| PT2101731T (pt) | 2006-11-21 | 2018-04-18 | Jina Pharmaceuticals Inc | Endoxifeno para utilização no tratamento de cancro |
| US20090291134A1 (en) | 2006-11-21 | 2009-11-26 | Jina Pharmaceuticals, Inc. | Endoxifen methods and compositions in the treatment of psychiatric and neurodegenerative diseases |
| JP5720881B2 (ja) | 2011-01-31 | 2015-05-20 | 東芝ライテック株式会社 | Ｌｅｄランプ点灯装置および照明装置 |
-
2007
- 2007-11-21 PT PT78715638T patent/PT2101731T/pt unknown
- 2007-11-21 ES ES07871563.8T patent/ES2665917T3/es active Active
- 2007-11-21 DK DK07871563.8T patent/DK2101731T3/en active
- 2007-11-21 CA CA2669913A patent/CA2669913C/en active Active
- 2007-11-21 JP JP2009538518A patent/JP2010510327A/ja active Pending
- 2007-11-21 EP EP07871563.8A patent/EP2101731B1/en not_active Revoked
- 2007-11-21 PL PL07871563T patent/PL2101731T3/pl unknown
- 2007-11-21 IN IN139MUN2014 patent/IN2014MN00139A/en unknown
- 2007-11-21 HU HUE07871563A patent/HUE037109T2/hu unknown
- 2007-11-21 WO PCT/US2007/085443 patent/WO2008070463A2/en not_active Ceased
- 2007-11-21 US US12/515,261 patent/US9333190B2/en active Active
-
2016
- 2016-04-27 US US15/139,687 patent/US10376479B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| DK2101731T3 (en) | 2018-04-16 |
| HUE037109T2 (hu) | 2018-08-28 |
| PT2101731T (pt) | 2018-04-18 |
| JP2010510327A (ja) | 2010-04-02 |
| EP2101731A2 (en) | 2009-09-23 |
| US20100112041A1 (en) | 2010-05-06 |
| WO2008070463A3 (en) | 2008-11-06 |
| CA2669913A1 (en) | 2008-06-12 |
| ES2665917T3 (es) | 2018-04-30 |
| US10376479B2 (en) | 2019-08-13 |
| EP2101731B1 (en) | 2018-01-31 |
| WO2008070463A9 (en) | 2008-09-18 |
| EP2101731A4 (en) | 2011-04-20 |
| CA2669913C (en) | 2012-09-18 |
| US20160346230A1 (en) | 2016-12-01 |
| WO2008070463A2 (en) | 2008-06-12 |
| US9333190B2 (en) | 2016-05-10 |
| IN2014MN00139A (show.php) | 2015-06-19 |
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