PL2064337T3 - Oparty na FACS i białku reporterowym układ do wysokowydajnego opracowywania białek terapeutycznych - Google Patents
Oparty na FACS i białku reporterowym układ do wysokowydajnego opracowywania białek terapeutycznychInfo
- Publication number
- PL2064337T3 PL2064337T3 PL07838397T PL07838397T PL2064337T3 PL 2064337 T3 PL2064337 T3 PL 2064337T3 PL 07838397 T PL07838397 T PL 07838397T PL 07838397 T PL07838397 T PL 07838397T PL 2064337 T3 PL2064337 T3 PL 2064337T3
- Authority
- PL
- Poland
- Prior art keywords
- facs
- based system
- high throughput
- therapeutic proteins
- reporter protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1086—Preparation or screening of expression libraries, e.g. reporter assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70592—CD52
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84622306P | 2006-09-20 | 2006-09-20 | |
| US84770506P | 2006-09-27 | 2006-09-27 | |
| EP07838397A EP2064337B1 (en) | 2006-09-20 | 2007-09-18 | A facs-and reporter protein-based system for high throughput development of therapeutic proteins |
| PCT/US2007/020180 WO2008036255A2 (en) | 2006-09-20 | 2007-09-18 | A facs-and reporter protein-based system for high throughput development of therapeutic proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2064337T3 true PL2064337T3 (pl) | 2012-12-31 |
Family
ID=39201056
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07838397T PL2064337T3 (pl) | 2006-09-20 | 2007-09-18 | Oparty na FACS i białku reporterowym układ do wysokowydajnego opracowywania białek terapeutycznych |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20090239235A1 (pl) |
| EP (1) | EP2064337B1 (pl) |
| AR (1) | AR062916A1 (pl) |
| ES (1) | ES2388003T3 (pl) |
| PL (1) | PL2064337T3 (pl) |
| PT (1) | PT2064337E (pl) |
| WO (1) | WO2008036255A2 (pl) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2404869A1 (en) * | 2010-07-06 | 2012-01-11 | Ammonia Casale S.A. | Process for producing ammonia synthesis gas |
| US9821159B2 (en) | 2010-11-16 | 2017-11-21 | The Board Of Trustees Of The Leland Stanford Junior University | Stimulation devices and methods |
| EP2640461B1 (en) | 2010-11-16 | 2019-06-19 | The Board Of Trustees Of The Leland Stanford Junior University | Systems for treatment of dry eye |
| EP2967817B1 (en) | 2013-03-12 | 2021-03-10 | Oculeve, Inc. | Implant delivery devices and systems |
| HK1220934A1 (zh) | 2013-04-19 | 2017-05-19 | Oculeve, Inc. | 鼻刺激装置和方法 |
| EP3110405B1 (en) | 2014-02-25 | 2020-05-06 | Oculeve, Inc. | Polymer formulations for nasolacrimal stimulation |
| EP3673952A1 (en) | 2014-07-25 | 2020-07-01 | Oculeve, Inc. | Stimulation patterns for treating dry eye |
| AU2015335772B2 (en) | 2014-10-22 | 2020-07-09 | Oculeve, Inc. | Contact lens for increasing tear production |
| WO2016065215A1 (en) | 2014-10-22 | 2016-04-28 | Oculeve, Inc. | Stimulation devices and methods for treating dry eye |
| US10137222B2 (en) | 2015-03-27 | 2018-11-27 | 3M Innovative Properties Company | Fibrin composition, method and wound articles |
| HUE069884T2 (hu) * | 2015-10-09 | 2025-04-28 | Genzyme Corp | Javított flare (áramlási citometriával csillapított reporter expresszió) technológia gyors tömeges válogatáshoz |
| US10426958B2 (en) | 2015-12-04 | 2019-10-01 | Oculeve, Inc. | Intranasal stimulation for enhanced release of ocular mucins and other tear proteins |
| US10252048B2 (en) | 2016-02-19 | 2019-04-09 | Oculeve, Inc. | Nasal stimulation for rhinitis, nasal congestion, and ocular allergies |
| AU2017260237A1 (en) | 2016-05-02 | 2018-11-22 | Oculeve, Inc. | Intranasal stimulation for treatment of meibomian gland disease and blepharitis |
| WO2018067622A1 (en) | 2016-10-05 | 2018-04-12 | 3M Innovative Properties Company | Fibrinogen composition, method and wound articles |
| US11827754B2 (en) | 2016-10-05 | 2023-11-28 | 3M Innovative Properties Company | Fibrin composition comprising carrier material, method and wound articles |
| US20180119192A1 (en) * | 2016-10-07 | 2018-05-03 | Genzyme Corporation | Early post-transfection isolation of cells (epic) for biologics production |
| US10610095B2 (en) | 2016-12-02 | 2020-04-07 | Oculeve, Inc. | Apparatus and method for dry eye forecast and treatment recommendation |
| MX2023005938A (es) | 2020-11-19 | 2023-05-29 | Genzyme Corp | Sistema de indicadores multiples de expresion atenuada de indicadores por citometria de flujo (flare) y sus metodos de uso. |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4937190A (en) * | 1987-10-15 | 1990-06-26 | Wisconsin Alumni Research Foundation | Translation enhancer |
| WO1998037189A1 (en) * | 1997-02-25 | 1998-08-27 | Qbi Enterprises Ltd. | Ires sequences with high translational efficiency and expression vectors containing the sequence |
| GB9815909D0 (en) * | 1998-07-21 | 1998-09-16 | Btg Int Ltd | Antibody preparation |
| AU2001236624A1 (en) | 2000-02-02 | 2001-08-14 | Iconix Pharmaceuticals, Inc. | Rapid, parallel identification of cell lines |
| WO2002070710A1 (en) * | 2001-03-01 | 2002-09-12 | University Of California | Method to identify ires elements |
| DE10143237A1 (de) * | 2001-09-04 | 2003-03-20 | Icon Genetics Ag | Herstellung künstlicher interner ribosomaler Eingangsstellenelemente (Ires-Elemente) |
| DE10143238A1 (de) * | 2001-09-04 | 2003-03-20 | Icon Genetics Ag | Identifizierung eukaryotischer interner Ribosomen-Eingangsstellen (IRES)-Elemente |
| US7119187B2 (en) * | 2002-07-09 | 2006-10-10 | National Health Research Institutes | Internal ribosome entry site of the labial gene for protein expression |
| DK2332972T3 (en) * | 2003-06-24 | 2018-04-23 | Genzyme Corp | Hitherto UNKNOWN BETA-ACTIN AND RPS21 PROMOTORS AND APPLICATIONS |
| ES2384391T3 (es) * | 2004-11-08 | 2012-07-04 | Chromagenics B.V. | Selección de células hospedantes que expresan proteína a altos niveles |
| EA010863B1 (ru) * | 2004-11-08 | 2008-12-30 | Хромагеникс Б.В. | Отбор клеток-хозяев, экспрессирующих белок на высоких уровнях |
-
2007
- 2007-09-18 EP EP07838397A patent/EP2064337B1/en active Active
- 2007-09-18 PL PL07838397T patent/PL2064337T3/pl unknown
- 2007-09-18 PT PT07838397T patent/PT2064337E/pt unknown
- 2007-09-18 US US12/441,806 patent/US20090239235A1/en not_active Abandoned
- 2007-09-18 WO PCT/US2007/020180 patent/WO2008036255A2/en not_active Ceased
- 2007-09-18 ES ES07838397T patent/ES2388003T3/es active Active
- 2007-09-20 AR ARP070104155A patent/AR062916A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR062916A1 (es) | 2008-12-17 |
| EP2064337A2 (en) | 2009-06-03 |
| PT2064337E (pt) | 2012-07-26 |
| EP2064337B1 (en) | 2012-07-18 |
| WO2008036255A3 (en) | 2008-07-24 |
| US20090239235A1 (en) | 2009-09-24 |
| WO2008036255A2 (en) | 2008-03-27 |
| ES2388003T3 (es) | 2012-10-05 |
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