PL2018169T3 - Zastosowanie 4,17β-dihydroksyandrost-4-en-3-onu do leczenia raków - Google Patents

Zastosowanie 4,17β-dihydroksyandrost-4-en-3-onu do leczenia raków

Info

Publication number
PL2018169T3
PL2018169T3 PL07725140T PL07725140T PL2018169T3 PL 2018169 T3 PL2018169 T3 PL 2018169T3 PL 07725140 T PL07725140 T PL 07725140T PL 07725140 T PL07725140 T PL 07725140T PL 2018169 T3 PL2018169 T3 PL 2018169T3
Authority
PL
Poland
Prior art keywords
dihydroxyandrost
ene
beta
treating cancers
hormone
Prior art date
Application number
PL07725140T
Other languages
English (en)
Inventor
Alexander Tobias Teichmann
Original Assignee
Mabel Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mabel Gmbh filed Critical Mabel Gmbh
Publication of PL2018169T3 publication Critical patent/PL2018169T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26Androgens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL07725140T 2006-05-12 2007-05-11 Zastosowanie 4,17β-dihydroksyandrost-4-en-3-onu do leczenia raków PL2018169T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US74712406P 2006-05-12 2006-05-12
EP06009894A EP1854465A1 (en) 2006-05-12 2006-05-12 Use of 4,17 beta-dihydroxyandrost-4-ene-3-one for treating cancers
EP07725140A EP2018169B1 (en) 2006-05-12 2007-05-11 Use of 4,17 beta-dihydroxyandrost-4-ene-3-one for treating cancers
PCT/EP2007/004220 WO2007131736A2 (en) 2006-05-12 2007-05-11 Use of 4, 17 beta-dihydroxyandrost-4-ene-3-one for treating cancers

Publications (1)

Publication Number Publication Date
PL2018169T3 true PL2018169T3 (pl) 2011-04-29

Family

ID=37075285

Family Applications (2)

Application Number Title Priority Date Filing Date
PL07725140T PL2018169T3 (pl) 2006-05-12 2007-05-11 Zastosowanie 4,17β-dihydroksyandrost-4-en-3-onu do leczenia raków
PL07725141T PL2018170T3 (pl) 2006-05-12 2007-05-11 Lek na raka sutka

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL07725141T PL2018170T3 (pl) 2006-05-12 2007-05-11 Lek na raka sutka

Country Status (15)

Country Link
US (3) US9138477B2 (pl)
EP (3) EP1854465A1 (pl)
JP (2) JP5363310B2 (pl)
KR (2) KR101403893B1 (pl)
CN (2) CN101443016B (pl)
AT (1) ATE487483T1 (pl)
AU (2) AU2007251823B2 (pl)
CA (2) CA2651354C (pl)
DE (1) DE602007010447D1 (pl)
DK (2) DK2018169T3 (pl)
ES (2) ES2391839T3 (pl)
PL (2) PL2018169T3 (pl)
PT (2) PT2018169E (pl)
SI (2) SI2018170T1 (pl)
WO (2) WO2007131737A2 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1854465A1 (en) 2006-05-12 2007-11-14 Alexander Tobias Teichmann Use of 4,17 beta-dihydroxyandrost-4-ene-3-one for treating cancers
ES2574933T3 (es) * 2007-11-13 2016-06-23 Athenion Ag Esteroides de C-19 para usos cosméticos
ES2628507T3 (es) 2007-11-13 2017-08-03 Athenion Ag Esteroides C-19 para el tratamiento de la celulitis
FR2964323B1 (fr) * 2010-09-08 2012-11-09 Jean Pierre Raynaud Utilisation de la testosterone chez un patient en deficit androgenique et atteint d'un cancer de la prostate
AU2011308775B2 (en) * 2010-10-01 2016-11-17 Indiana University Research And Technology Corporation Treatment of symptoms associated with menopause
JP6091431B2 (ja) * 2011-01-31 2017-03-15 ルコラス−エム.ディー.リミテッド 医薬的使用
WO2015055179A1 (de) * 2013-10-15 2015-04-23 Chelac Holding Gmbh Steroid-carbonsäureester, zusammensetzungen, enthaltend steroid-carbonsäureester und verwendung dieser bei lokal topischer applikation für kosmetische oder dermatologische zwecke
SI3040075T1 (en) * 2014-12-30 2018-04-30 Curadis Gmbh C-19 STEROIDS FOR INHIBITION OF NEVASCULARIZATION
US20190201526A1 (en) * 2016-09-07 2019-07-04 The Wistar Institute Of Anatomy And Biology Methods and Compositions for Treating Cancers by Inhibiting Estrogen Signaling in Myeloid-Derived Suppressor Cells
CN108727453A (zh) * 2017-04-20 2018-11-02 华东理工大学 新型pd-1抑制剂及其应用
EP3632445A1 (en) * 2018-10-04 2020-04-08 Curadis GmbH Combinations with a c-19 steroid for treating cancers
RU2679625C1 (ru) * 2018-11-08 2019-02-12 Ильясов Шамиль Сионович ПРИМЕНЕНИЕ 3-О-СУЛЬФАМОИЛОКСИ-6-ОКСА-7β-МЕТИЛ-D-ГОМО-8α-ЭСТРА-1,3,5(10)-ТРИЕН-17а-ОНА ДЛЯ ЛЕЧЕНИЯ РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ, ВКЛЮЧАЯ ТРИЖДЫ-НЕГАТИВНУЮ ФОРМУ, И СПОСОБ ЕГО ПОЛУЧЕНИЯ
EP3666276A1 (en) 2018-12-14 2020-06-17 dcic Biopharmaceutical Limited Medication against estrogen-receptor beta (erbeta) positive breast tumor

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA639855A (en) 1962-04-17 Societa Farmaceutici Italia 4-halo-3-keto-.delta.4-steroids
BE552152A (pl) *
US2744120A (en) 1953-01-14 1956-05-01 Olin Mathieson 1-dehydrotestololactone
US2762818A (en) * 1955-05-26 1956-09-11 Searle & Co 4-hydroxytestosterone and esters thereof
US4235893A (en) * 1978-05-08 1980-11-25 Brodie Angela M Ester derivatives of 4-hydroxy-4-androstene-3,17-dione and a method for inhibiting estrogen biosynthesis
US4289762A (en) 1980-06-27 1981-09-15 Merrell Dow Pharmaceuticals Inc. 10-(1,2-Propadienyl) steroids as irreversible aromatase inhibitors
US4322416A (en) * 1980-06-27 1982-03-30 Merrell Dow Pharmaceuticals Inc. 10-Alkynyl steroids
DE3121153A1 (de) 1981-05-22 1982-12-09 Schering Ag, 1000 Berlin Und 4619 Bergkamen "verwendung von aromatase-hemmern zur prophylaxe und therapie der prostatahyperplasie"
DE3362176D1 (en) 1982-07-14 1986-03-27 Akzo Nv Novel 19-thio-androstane derivatives
GB8721384D0 (en) * 1987-09-11 1987-10-21 Erba Farmitalia 17-substituted andro-sta-1 4-dien-3-one derivatives
AU7736300A (en) 1999-09-30 2001-04-30 Hollis-Eden Pharmaceuticals, Inc. Therapeutic treatment of androgen receptor driven conditions
DE10049736A1 (de) * 2000-09-29 2002-04-18 Jenapharm Gmbh 17alpha-Fluoralkylsteroide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
DE10054294A1 (de) * 2000-11-02 2002-05-16 Heinrich Wieland Topische Behandlung bei der Mastalgie
US20030229063A1 (en) * 2002-06-05 2003-12-11 Llewellyn William Charles Use of 4-hydroxytestosterone to lower estrogen levels in humans
US20030049307A1 (en) * 2002-08-15 2003-03-13 Gyurik Robert J. Pharmaceutical composition
GB2398495B (en) * 2003-01-23 2007-08-22 Kent G Lau A drug delivery preparation comprising at least one anti-tumour drug and a topical carrier for the drug
TW200510384A (en) * 2003-08-07 2005-03-16 Schering Corp Novel farnesyl protein transferase inhibitors as antitumor agents
CA2542096A1 (en) 2003-10-09 2005-04-21 Aton Pharma, Inc. Thiophene and benzothiophene hydroxamic acid derivatives
WO2005062760A2 (en) * 2003-12-12 2005-07-14 University Of Rochester Non-androgen dependent roles for androgen receptor and non-androgen related inhibitors of androgen receptor
EP1802341A1 (en) 2004-07-16 2007-07-04 Pfizer Products Inc. Combination treatment for non-hematologic malignancies using an anti-igf-1r antibody
EP1854465A1 (en) 2006-05-12 2007-11-14 Alexander Tobias Teichmann Use of 4,17 beta-dihydroxyandrost-4-ene-3-one for treating cancers

Also Published As

Publication number Publication date
PT2018170E (pt) 2012-10-25
ES2355530T3 (es) 2011-03-28
EP2018169B1 (en) 2010-11-10
AU2007251822A1 (en) 2007-11-22
EP2018169A2 (en) 2009-01-28
US9114163B2 (en) 2015-08-25
DK2018170T3 (da) 2012-10-22
KR20090010189A (ko) 2009-01-29
US20090111784A1 (en) 2009-04-30
WO2007131736A2 (en) 2007-11-22
PL2018170T3 (pl) 2013-01-31
CN101443017B (zh) 2013-07-31
WO2007131736A3 (en) 2008-03-06
US9138477B2 (en) 2015-09-22
KR20090009855A (ko) 2009-01-23
SI2018169T1 (sl) 2011-02-28
CA2651354C (en) 2015-11-17
JP5363310B2 (ja) 2013-12-11
JP2009536932A (ja) 2009-10-22
WO2007131737A3 (en) 2008-05-02
EP2018170B1 (en) 2012-07-25
CA2652057C (en) 2015-07-07
AU2007251823B2 (en) 2012-09-06
AU2007251822B2 (en) 2012-08-16
JP2009536931A (ja) 2009-10-22
KR101403893B1 (ko) 2014-06-20
EP2018170A2 (en) 2009-01-28
KR101403895B1 (ko) 2014-06-20
ATE487483T1 (de) 2010-11-15
CA2651354A1 (en) 2007-11-22
SI2018170T1 (sl) 2012-12-31
JP5363309B2 (ja) 2013-12-11
CA2652057A1 (en) 2007-11-22
US20100061975A1 (en) 2010-03-11
DK2018169T3 (da) 2011-02-07
DE602007010447D1 (de) 2010-12-23
AU2007251823A1 (en) 2007-11-22
EP1854465A1 (en) 2007-11-14
CN101443017A (zh) 2009-05-27
US9610292B2 (en) 2017-04-04
ES2391839T3 (es) 2012-11-30
CN101443016A (zh) 2009-05-27
US20160030448A1 (en) 2016-02-04
WO2007131737A2 (en) 2007-11-22
CN101443016B (zh) 2012-09-05
PT2018169E (pt) 2011-01-19

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