PL2007391T3 - Kombinacja zawierająca A) pirymidyloaminobenzamid i B) inhibitor kinazy THR315LLE - Google Patents

Kombinacja zawierająca A) pirymidyloaminobenzamid i B) inhibitor kinazy THR315LLE

Info

Publication number
PL2007391T3
PL2007391T3 PL07727881T PL07727881T PL2007391T3 PL 2007391 T3 PL2007391 T3 PL 2007391T3 PL 07727881 T PL07727881 T PL 07727881T PL 07727881 T PL07727881 T PL 07727881T PL 2007391 T3 PL2007391 T3 PL 2007391T3
Authority
PL
Poland
Prior art keywords
thr315lle
combination
kinase inhibitor
pyrimidylaminobenzamide compound
pyrimidylaminobenzamide
Prior art date
Application number
PL07727881T
Other languages
English (en)
Inventor
Paul W Manley
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL2007391T3 publication Critical patent/PL2007391T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL07727881T 2006-04-07 2007-04-05 Kombinacja zawierająca A) pirymidyloaminobenzamid i B) inhibitor kinazy THR315LLE PL2007391T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US79043806P 2006-04-07 2006-04-07
US79115006P 2006-04-11 2006-04-11
PCT/EP2007/053413 WO2007116029A2 (en) 2006-04-07 2007-04-05 Combination comprising a) a pyrimidylaminobenzamide compound, and b) a thr315lle kinase inhibitor
EP07727881.0A EP2007391B8 (en) 2006-04-07 2007-04-05 Combination comprising a) a pyrimidylaminobenzamide compound, and b) a thr315ile kinase inhibitor

Publications (1)

Publication Number Publication Date
PL2007391T3 true PL2007391T3 (pl) 2013-05-31

Family

ID=38229305

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07727881T PL2007391T3 (pl) 2006-04-07 2007-04-05 Kombinacja zawierająca A) pirymidyloaminobenzamid i B) inhibitor kinazy THR315LLE

Country Status (13)

Country Link
US (1) US20090286803A1 (pl)
EP (2) EP2007391B8 (pl)
JP (2) JP2009532440A (pl)
KR (1) KR20090023561A (pl)
AU (1) AU2007235900A1 (pl)
BR (1) BRPI0710496A2 (pl)
CA (1) CA2647803C (pl)
ES (1) ES2400375T3 (pl)
MX (1) MX2008012971A (pl)
PL (1) PL2007391T3 (pl)
PT (1) PT2007391E (pl)
RU (2) RU2481840C2 (pl)
WO (1) WO2007116029A2 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8217045B2 (en) * 2007-04-17 2012-07-10 Novartis Ag Organic compounds
JO3265B1 (ar) 2008-12-09 2018-09-16 Novartis Ag مثبطات بيريديلوكسى اندولات vegf-r2 واستخدامها لعلاج المرض
MX2012005023A (es) * 2009-10-30 2012-06-19 Ariad Pharma Inc Metodos y composiciones para tratar cancer.
CN102822141A (zh) * 2010-01-20 2012-12-12 普罗诺瓦生物医药挪威公司 水杨酸脂肪酸衍生物
CN109730996B (zh) * 2017-03-01 2021-08-24 浙江大学 喹啉结构类型雄激素受体拮抗剂及其应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002068415A1 (en) 2000-12-21 2002-09-06 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
AU2002337410A1 (en) * 2001-09-05 2003-03-18 Oncopharm Corporation Treatment of chronic myelogenous leukemia, resistant or intolerant to sti571, involving homoharringtonine alone or combined with other agents
EP1578346A4 (en) * 2001-12-04 2007-11-28 Onyx Pharma Inc INHIBITORS OF THE RAF-MEK-ERK PATHWAY TO TREAT CANCER
AR037647A1 (es) 2002-05-29 2004-12-01 Novartis Ag Derivados de diarilurea utiles para el tratamiento de enfermedades dependientes de la cinasa de proteina
FR2841116B1 (fr) 2002-06-19 2004-11-26 Seb Sa Cafetiere du type expresso a reservoir d'eau amovible
GB0215676D0 (en) 2002-07-05 2002-08-14 Novartis Ag Organic compounds
AU2003270668A1 (en) * 2002-09-19 2004-04-08 University Of South Florida Method of treating leukemia with a combination of suberoylanilide hydromaxic acid and imatinib mesylate
DE10330916A1 (de) 2003-07-04 2005-02-03 Pilz Gmbh & Co. Kg Vorrichtung und Verfahren zum automatisierten Steuern eines Betriebsablaufs bei einer technischen Anlage
US7338957B2 (en) 2003-08-28 2008-03-04 Irm Llc Compounds and compositions as protein kinase inhibitors
RU2401265C2 (ru) 2004-06-10 2010-10-10 Айрм Ллк Соединения и композиции в качестве ингибиторов протеинкиназы
KR20070050918A (ko) * 2004-07-02 2007-05-16 뉴텍 파마 피엘씨 암의 치료
PE20060664A1 (es) 2004-09-15 2006-08-04 Novartis Ag Amidas biciclicas como inhibidores de cinasa
GB0421525D0 (en) * 2004-09-28 2004-10-27 Novartis Ag Inhibitors of protein kineses
WO2007056023A2 (en) * 2005-11-02 2007-05-18 Targegen, Inc. Thiazole inhibitors targeting resistant kinase mutations

Also Published As

Publication number Publication date
ES2400375T8 (es) 2013-09-10
EP2007391B8 (en) 2013-05-29
CA2647803C (en) 2014-05-27
PT2007391E (pt) 2013-03-11
EP2574340A2 (en) 2013-04-03
MX2008012971A (es) 2008-10-15
RU2008143704A (ru) 2010-05-20
KR20090023561A (ko) 2009-03-05
EP2007391B1 (en) 2012-12-19
WO2007116029A3 (en) 2008-12-11
BRPI0710496A2 (pt) 2011-08-16
EP2574340A3 (en) 2013-04-17
CA2647803A1 (en) 2007-10-18
EP2007391A2 (en) 2008-12-31
JP2009532440A (ja) 2009-09-10
WO2007116029A2 (en) 2007-10-18
ES2400375T3 (es) 2013-04-09
RU2481840C2 (ru) 2013-05-20
AU2007235900A1 (en) 2007-10-18
RU2013103746A (ru) 2014-08-10
JP2013224304A (ja) 2013-10-31
US20090286803A1 (en) 2009-11-19

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