PL1991680T3 - Układ do ekspresji ortogonalnych składników translacji w eubakteryjnych komórkach gospodarza - Google Patents

Układ do ekspresji ortogonalnych składników translacji w eubakteryjnych komórkach gospodarza

Info

Publication number
PL1991680T3
PL1991680T3 PL07752601T PL07752601T PL1991680T3 PL 1991680 T3 PL1991680 T3 PL 1991680T3 PL 07752601 T PL07752601 T PL 07752601T PL 07752601 T PL07752601 T PL 07752601T PL 1991680 T3 PL1991680 T3 PL 1991680T3
Authority
PL
Poland
Prior art keywords
expression
host cells
translation components
orthogonal translation
eubacterial host
Prior art date
Application number
PL07752601T
Other languages
English (en)
Inventor
Youngha Ryu
Peter G Schultz
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of PL1991680T3 publication Critical patent/PL1991680T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL07752601T 2006-03-09 2007-03-07 Układ do ekspresji ortogonalnych składników translacji w eubakteryjnych komórkach gospodarza PL1991680T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US78097306P 2006-03-09 2006-03-09
US78349706P 2006-03-17 2006-03-17
US85533606P 2006-10-29 2006-10-29
PCT/US2007/005914 WO2007103490A2 (en) 2006-03-09 2007-03-07 System for the expression of orthogonal translation components in eubacterial host cells
EP07752601.0A EP1991680B1 (en) 2006-03-09 2007-03-07 System for the expression of orthogonal translation components in eubacterial host cells

Publications (1)

Publication Number Publication Date
PL1991680T3 true PL1991680T3 (pl) 2014-01-31

Family

ID=38475556

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07752601T PL1991680T3 (pl) 2006-03-09 2007-03-07 Układ do ekspresji ortogonalnych składników translacji w eubakteryjnych komórkach gospodarza

Country Status (14)

Country Link
US (3) US7960141B2 (pl)
EP (1) EP1991680B1 (pl)
JP (1) JP5589186B2 (pl)
KR (1) KR20080106430A (pl)
CN (1) CN101400796B (pl)
AU (1) AU2007223830A1 (pl)
BR (1) BRPI0709935A2 (pl)
CA (1) CA2638763A1 (pl)
ES (1) ES2432391T3 (pl)
IL (1) IL193394A0 (pl)
MX (1) MX2008011470A (pl)
PL (1) PL1991680T3 (pl)
PT (1) PT1991680E (pl)
WO (1) WO2007103490A2 (pl)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1456360B1 (en) * 2001-04-19 2015-06-03 The Scripps Research Institute Methods and composition for the production of orthoganal trna-aminoacyltrna synthetase pairs
US6927042B2 (en) * 2002-10-16 2005-08-09 The Scripps Research Institute Glycoprotein synthesis
US7618775B2 (en) 2003-04-17 2009-11-17 The Scripps Research Institute Expanding the eukaryotic genetic code
US7638297B2 (en) 2003-07-07 2009-12-29 The Scripps Research Institute Compositions of orthogonal lysyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof
WO2006036779A2 (en) * 2004-09-22 2006-04-06 The Scripps Research Institute Site-specific labeling of proteins for nmr studies
CN102827827B (zh) 2004-10-27 2014-10-29 斯克利普斯研究院 体内掺入非天然氨基酸的正交翻译组分
PL1991680T3 (pl) 2006-03-09 2014-01-31 Scripps Research Inst Układ do ekspresji ortogonalnych składników translacji w eubakteryjnych komórkach gospodarza
EP1994165B1 (en) 2006-03-16 2014-11-05 The Scripps Research Institute Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine
WO2007139870A1 (en) 2006-05-23 2007-12-06 The Scripps Research Institute Genetically encoded fluorescent coumarin amino acids
BRPI0716963A2 (pt) 2006-09-21 2013-11-05 Scripps Research Inst Expressão geneticamente programada de proteínas seletivamente sulfatadas em eubactéria
US20080166766A1 (en) 2006-10-18 2008-07-10 The Scripps Research Institute Genetic incorporation of unnatural amino acids into proteins in mammalian cells
EP2220218A4 (en) * 2007-11-02 2010-12-08 Scripps Research Inst GENETICALLY ENCODED BORONATE AMINO ACID
AU2008335778B2 (en) * 2007-12-11 2014-04-10 The Scripps Research Institute In vivo unnatural amino acid expression in the methylotrophic yeast Pichia pastoris
AU2009210677A1 (en) * 2008-02-08 2009-08-13 The Scripps Research Institute Breaking immunological tolerance with a genetically encoded unnatural amino acid
CA2738033C (en) 2008-09-26 2019-11-26 Ambrx, Inc. Non-natural amino acid replication-dependent microorganisms and vaccines
US20090197339A1 (en) * 2008-12-10 2009-08-06 The Scripps Research Institute In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris
US8609383B2 (en) 2008-12-10 2013-12-17 The Scripps Research Institute Production of carrier-peptide conjugates using chemically reactive unnatural amino acids
AU2011291943B2 (en) * 2010-08-17 2015-01-22 Ambrx, Inc. Modified relaxin polypeptides and their uses
KR20160027217A (ko) 2012-05-23 2016-03-09 에프. 호프만-라 로슈 아게 내배엽 및 간세포를 수득하고 사용하는 조성물 및 방법
UY35368A (es) 2013-03-08 2014-10-31 Irm Llc Péptidos y composiciones para el tratamiento de daño articular
WO2015009948A1 (en) 2013-07-19 2015-01-22 Regents Of The University Of California Milk fat globule epidermal growth factor 8 regulates fatty acid uptake
KR20240045351A (ko) 2016-11-14 2024-04-05 노파르티스 아게 연골 손상 및 관절염 치료 방법 및 조성물
EP3538546B1 (en) 2016-11-14 2025-01-08 Novartis AG Compositions, methods, and therapeutic uses related to fusogenic protein minion
KR102670432B1 (ko) 2017-02-08 2024-05-28 브리스톨-마이어스 스큅 컴퍼니 약동학적 인핸서를 포함하는 변형된 렐락신 폴리펩티드 및 그의 용도
CA3157470A1 (en) * 2019-11-05 2021-05-14 Neil Butler Biosynthesis of para-nitro-l-phenylalanine
CN111304234A (zh) * 2020-02-27 2020-06-19 江南大学 一种适用于枯草芽孢杆菌的非天然氨基酸利用工具
CN113322267B (zh) * 2021-03-15 2024-01-05 天津大学 系统在提高非天然氨基酸的插入效率中的应用
WO2024091824A1 (en) 2022-10-26 2024-05-02 Ada Forsyth Institute, Inc. Differentiation and reprogramming of chondrocyte

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5024939A (en) * 1987-07-09 1991-06-18 Genentech, Inc. Transient expression system for producing recombinant protein
JP2002526103A (ja) 1998-10-08 2002-08-20 アストラゼネカ・アクチエボラーグ 微細組み立てセル注入器
ATE508200T1 (de) 1999-02-23 2011-05-15 Caliper Life Sciences Inc Sequenzierung durch inkorporation
EP1456360B1 (en) 2001-04-19 2015-06-03 The Scripps Research Institute Methods and composition for the production of orthoganal trna-aminoacyltrna synthetase pairs
US8220494B2 (en) 2002-09-25 2012-07-17 California Institute Of Technology Microfluidic large scale integration
DE60327369D1 (de) * 2002-10-16 2009-06-04 Scripps Research Inst Stellenspezifischer einbau von ketoaminosäuren in proteine
US6927042B2 (en) * 2002-10-16 2005-08-09 The Scripps Research Institute Glycoprotein synthesis
US7642085B2 (en) 2002-12-22 2010-01-05 The Scripps Research Institute Protein arrays
US7618775B2 (en) * 2003-04-17 2009-11-17 The Scripps Research Institute Expanding the eukaryotic genetic code
EP2378288B1 (en) * 2003-06-18 2015-09-09 The Scripps Research Institute Unnatural reactive amino acid genetic code additions
US7638297B2 (en) * 2003-07-07 2009-12-29 The Scripps Research Institute Compositions of orthogonal lysyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof
US7527943B2 (en) 2003-07-07 2009-05-05 The Scripps Research Institute Compositions of orthogonal glutamyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof
US20060160175A1 (en) * 2003-07-07 2006-07-20 The Scripps Research Institute Compositions of orthogonal leucyl-trna and aminoacyl-trna synthetase pairs and uses thereof
US7494796B2 (en) 2003-10-14 2009-02-24 The Scripps Research Institute Site-specific incorporation of redox active amino acids into proteins
EP1725251A4 (en) 2003-12-18 2009-07-01 Scripps Research Inst SELECTIVE PROCESSING OF 5-HYDROXYTRYPTOPHANE IN PROTEINS IN MAMMALIAN CELLS
MXPA06013586A (es) 2004-05-25 2007-11-09 Scripss Res Inst Incorporacion especifica del sitio de aminoacidos no naturales que contienen atomos pesados en proteinas para la determinacion de la estructura cristalina.
JP2008513039A (ja) 2004-09-21 2008-05-01 ザ スクリップス リサーチ インスティテュート 真正細菌の蛋白質へのアルキニルアミノ酸のインビボ組込み
WO2006034410A2 (en) * 2004-09-21 2006-03-30 The Scripps Resarch Institute Adding photoregulated amino acids to the genetic code
WO2006036779A2 (en) * 2004-09-22 2006-04-06 The Scripps Research Institute Site-specific labeling of proteins for nmr studies
US7378263B2 (en) * 2004-10-20 2008-05-27 The Scripps Research Institute In vivo site-specific incorporation of N-acetyl-galactosamine amino acids in eubacteria
CN102827827B (zh) 2004-10-27 2014-10-29 斯克利普斯研究院 体内掺入非天然氨基酸的正交翻译组分
CN104789536A (zh) 2005-10-12 2015-07-22 斯克利普斯研究院 噬菌体展示多肽的选择性翻译后修饰
PL1991680T3 (pl) 2006-03-09 2014-01-31 Scripps Research Inst Układ do ekspresji ortogonalnych składników translacji w eubakteryjnych komórkach gospodarza
EP1994165B1 (en) * 2006-03-16 2014-11-05 The Scripps Research Institute Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine

Also Published As

Publication number Publication date
US20120252067A1 (en) 2012-10-04
CN101400796A (zh) 2009-04-01
US20090181429A1 (en) 2009-07-16
JP5589186B2 (ja) 2014-09-17
US8357512B2 (en) 2013-01-22
PT1991680E (pt) 2013-10-30
WO2007103490A2 (en) 2007-09-13
EP1991680A4 (en) 2009-10-21
EP1991680B1 (en) 2013-08-21
JP2009529328A (ja) 2009-08-20
AU2007223830A1 (en) 2007-09-13
KR20080106430A (ko) 2008-12-05
WO2007103490A3 (en) 2008-06-12
EP1991680A2 (en) 2008-11-19
US20070281335A1 (en) 2007-12-06
BRPI0709935A2 (pt) 2011-08-02
IL193394A0 (en) 2009-09-22
CN101400796B (zh) 2013-03-27
ES2432391T3 (es) 2013-12-03
CA2638763A1 (en) 2007-09-13
MX2008011470A (es) 2008-09-24
US8198044B2 (en) 2012-06-12
US7960141B2 (en) 2011-06-14

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