PL1937626T3 - Sposób i związki do otrzymywania salmeterolu - Google Patents
Sposób i związki do otrzymywania salmeteroluInfo
- Publication number
- PL1937626T3 PL1937626T3 PL06794800T PL06794800T PL1937626T3 PL 1937626 T3 PL1937626 T3 PL 1937626T3 PL 06794800 T PL06794800 T PL 06794800T PL 06794800 T PL06794800 T PL 06794800T PL 1937626 T3 PL1937626 T3 PL 1937626T3
- Authority
- PL
- Poland
- Prior art keywords
- salmeterol
- intermediates
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
- C07C217/10—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/16—Preparation of ethers by reaction of esters of mineral or organic acids with hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/17—Unsaturated ethers containing halogen
- C07C43/174—Unsaturated ethers containing halogen containing six-membered aromatic rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1298MU2005 | 2005-10-17 | ||
IN827MU2006 | 2006-05-31 | ||
EP06794800.0A EP1937626B1 (en) | 2005-10-17 | 2006-10-17 | Process and intermediates for the preparation of Salmeterol |
PCT/GB2006/003857 WO2007045857A1 (en) | 2005-10-17 | 2006-10-17 | Novel process |
Publications (1)
Publication Number | Publication Date |
---|---|
PL1937626T3 true PL1937626T3 (pl) | 2016-08-31 |
Family
ID=37716215
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL06794800T PL1937626T3 (pl) | 2005-10-17 | 2006-10-17 | Sposób i związki do otrzymywania salmeterolu |
Country Status (8)
Country | Link |
---|---|
US (1) | US8648214B2 (pl) |
EP (2) | EP1937626B1 (pl) |
JP (1) | JP5599974B2 (pl) |
AU (1) | AU2006303124B2 (pl) |
CA (2) | CA2838520C (pl) |
ES (1) | ES2570597T3 (pl) |
PL (1) | PL1937626T3 (pl) |
WO (1) | WO2007045857A1 (pl) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080319086A1 (en) * | 2007-06-20 | 2008-12-25 | Protia, Llc | Deuterium-enriched salmeterol |
CN101712622B (zh) * | 2009-11-10 | 2012-10-03 | 浙江万里学院 | 抗哮喘药物沙美特罗的制备方法 |
WO2012032546A2 (en) | 2010-09-08 | 2012-03-15 | Cadila Healthcare Limited | Process for the preparation of salmeterol and its intermediates |
CN102993031B (zh) * | 2011-09-19 | 2014-03-26 | 北京桑普生物化学技术有限公司 | 一种制备芳基多氧烷基季铵类化合物的方法 |
US20160168161A1 (en) * | 2013-07-25 | 2016-06-16 | Nissan Chemical Industies, Ltd. | Method for producing heterocyclic compound |
CN103641727A (zh) * | 2013-12-02 | 2014-03-19 | 山东永泰化工有限公司 | 一种羟萘酸沙美特罗的制备方法 |
US9447067B2 (en) | 2014-10-03 | 2016-09-20 | Amphastar Pahmaceuticals, Inc. | Method of preparing intermediate of salmeterol |
WO2016142582A1 (en) | 2015-03-11 | 2016-09-15 | Fermion Oy | Process for the preparation of crystalline salmeterol and its xinafoate salt |
WO2017168431A1 (en) * | 2016-03-30 | 2017-10-05 | Davuluri Ramamohan Rao | Process for the preparation of salmeterol xinafoate |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3468881A (en) * | 1966-08-15 | 1969-09-23 | Upjohn Co | Allylic amines |
ZW6584A1 (en) | 1983-04-18 | 1985-04-17 | Glaxo Group Ltd | Phenethanolamine derivatives |
US5011993A (en) | 1986-09-05 | 1991-04-30 | Schering Corporation | Method for the preparation of α1 [[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol |
US4952729A (en) | 1986-09-05 | 1990-08-28 | Schering-Plough Corp. | Intermediates in the preparation of alpha1(((1,1-dimethylethyl) amino) methyl)-4-hydroxy-1,3-benzenedimethanol |
PT95542B (pt) * | 1989-10-10 | 1999-09-30 | Glaxo Group Ltd | Processo para a prparacao de derivados de fenetanolamina |
JPH1112219A (ja) * | 1997-06-24 | 1999-01-19 | Chemprokasei Kaisha Ltd | ポリヒドロキシベンゾフェノン類の部分アルキル化法 |
US6620977B1 (en) * | 1998-01-30 | 2003-09-16 | Daiso Co., Ltd. | Process for producing butanetriol derivative |
ES2142771B1 (es) * | 1998-09-28 | 2001-01-01 | Vita Invest Sa | Nuevos derivados de la 6-(4-fenil-butoxi) hexilamina y procedimiento para la obtencion de salmeterol. |
JP2001247517A (ja) * | 2000-03-07 | 2001-09-11 | Sumitomo Chem Co Ltd | 溶液中のα−ハロエステル化合物の低減方法 |
FR2807039A1 (fr) * | 2000-03-31 | 2001-10-05 | Adir | NOUVEAU PROCEDE DE PREPARATION DE LA 11-AMINO-3-CHLORO-6,11- DIHYDRO-5,5-DIOXO-6-METHYL-DIBENZO[c,f][1,2]-THIAZEPINE ET APPLICATION A LA SYNTHESE DE LA TIANEPTINE |
GB0014546D0 (en) * | 2000-06-14 | 2000-08-09 | Glaxo Group Ltd | A novel process |
US6835857B2 (en) | 2002-03-05 | 2004-12-28 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Process for the manufacture of 4-(6-bromohexyloxy)-butylbenzene |
US20040152720A1 (en) * | 2002-12-20 | 2004-08-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powdered medicaments containing a tiotropium salt and salmeterol xinafoate |
-
2006
- 2006-10-17 WO PCT/GB2006/003857 patent/WO2007045857A1/en active Application Filing
- 2006-10-17 EP EP06794800.0A patent/EP1937626B1/en not_active Not-in-force
- 2006-10-17 AU AU2006303124A patent/AU2006303124B2/en not_active Ceased
- 2006-10-17 ES ES06794800T patent/ES2570597T3/es active Active
- 2006-10-17 JP JP2008536115A patent/JP5599974B2/ja not_active Expired - Fee Related
- 2006-10-17 PL PL06794800T patent/PL1937626T3/pl unknown
- 2006-10-17 CA CA2838520A patent/CA2838520C/en not_active Expired - Fee Related
- 2006-10-17 CA CA2625337A patent/CA2625337C/en not_active Expired - Fee Related
- 2006-10-17 EP EP13154981.8A patent/EP2641893A1/en not_active Withdrawn
-
2008
- 2008-04-16 US US12/103,999 patent/US8648214B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2838520C (en) | 2017-02-21 |
EP2641893A1 (en) | 2013-09-25 |
AU2006303124A1 (en) | 2007-04-26 |
EP1937626A1 (en) | 2008-07-02 |
CA2625337A1 (en) | 2007-04-26 |
EP1937626B1 (en) | 2016-02-17 |
JP5599974B2 (ja) | 2014-10-01 |
AU2006303124B2 (en) | 2013-03-28 |
ES2570597T3 (es) | 2016-05-19 |
CA2625337C (en) | 2014-03-18 |
CA2838520A1 (en) | 2007-04-26 |
US20080262267A1 (en) | 2008-10-23 |
WO2007045857A1 (en) | 2007-04-26 |
US8648214B2 (en) | 2014-02-11 |
JP2009513578A (ja) | 2009-04-02 |
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