PL1888643T3 - Przeciwciała przeciwko GM-CSF i ich zastosowania - Google Patents

Przeciwciała przeciwko GM-CSF i ich zastosowania

Info

Publication number
PL1888643T3
PL1888643T3 PL06742970T PL06742970T PL1888643T3 PL 1888643 T3 PL1888643 T3 PL 1888643T3 PL 06742970 T PL06742970 T PL 06742970T PL 06742970 T PL06742970 T PL 06742970T PL 1888643 T3 PL1888643 T3 PL 1888643T3
Authority
PL
Poland
Prior art keywords
uses therefor
csf antibodies
csf
antibodies
therefor
Prior art date
Application number
PL06742970T
Other languages
English (en)
Inventor
Stefan Steidl
Elisabeth Thomassen-Wolf
Original Assignee
Morphosys Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morphosys Ag filed Critical Morphosys Ag
Publication of PL1888643T3 publication Critical patent/PL1888643T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/243—Colony Stimulating Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL06742970T 2005-05-18 2006-05-17 Przeciwciała przeciwko GM-CSF i ich zastosowania PL1888643T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68200905P 2005-05-18 2005-05-18
EP06742970.4A EP1888643B1 (en) 2005-05-18 2006-05-17 Anti-gm-csf antibodies and uses therefor
PCT/EP2006/004696 WO2006122797A2 (en) 2005-05-18 2006-05-17 Anti-gm-csf antibodies and uses therefor

Publications (1)

Publication Number Publication Date
PL1888643T3 true PL1888643T3 (pl) 2015-04-30

Family

ID=37114333

Family Applications (2)

Application Number Title Priority Date Filing Date
PL19180152.1T PL3620171T3 (pl) 2005-05-18 2006-05-17 Przeciwciała anty-gm-csf i ich zastosowania
PL06742970T PL1888643T3 (pl) 2005-05-18 2006-05-17 Przeciwciała przeciwko GM-CSF i ich zastosowania

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL19180152.1T PL3620171T3 (pl) 2005-05-18 2006-05-17 Przeciwciała anty-gm-csf i ich zastosowania

Country Status (26)

Country Link
US (5) US7867495B2 (pl)
EP (4) EP3620171B1 (pl)
JP (2) JP5295759B2 (pl)
KR (1) KR101308087B1 (pl)
CN (2) CN103087190B (pl)
AR (1) AR053608A1 (pl)
AU (1) AU2006249062B2 (pl)
BR (1) BRPI0610796B8 (pl)
CA (1) CA2608498C (pl)
CY (2) CY1115920T1 (pl)
DK (2) DK3620171T3 (pl)
ES (2) ES2918209T3 (pl)
HR (2) HRP20220755T3 (pl)
HU (1) HUE058876T2 (pl)
IL (1) IL187375A (pl)
LT (1) LT3620171T (pl)
ME (1) ME02059B (pl)
NO (1) NO344992B1 (pl)
NZ (1) NZ564027A (pl)
PL (2) PL3620171T3 (pl)
PT (2) PT1888643E (pl)
RS (2) RS53743B1 (pl)
RU (1) RU2447085C2 (pl)
SI (2) SI1888643T1 (pl)
TW (1) TWI477512B (pl)
WO (1) WO2006122797A2 (pl)

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CA2641169C (en) * 2006-02-08 2017-05-02 Morphotek, Inc. Antigenic gm-csf peptides and antibodies to gm-csf
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US8398972B2 (en) 2006-11-21 2013-03-19 Kalobios Pharmaceuticals, Inc. Methods of treating dementia using a GM-CSF antagonist
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EP2914289B1 (en) 2012-10-31 2019-05-22 Takeda GmbH Lyophilized formulation comprising gm-csf neutralizing compound
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US11078264B2 (en) 2018-10-17 2021-08-03 University Of Connecticut Inhibiting granulocyte macrophage-colony stimulating factor (GM-CSF) prevents preterm birth
US20220010007A1 (en) 2018-11-09 2022-01-13 Kiniksa Pharmaeuticals, Ltd. Treatment for Giant Cell Arteritis
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Also Published As

Publication number Publication date
US7867495B2 (en) 2011-01-11
PT3620171T (pt) 2022-06-30
US20170218061A1 (en) 2017-08-03
TWI477512B (zh) 2015-03-21
CN101218255A (zh) 2008-07-09
JP5769744B2 (ja) 2015-08-26
US20200024340A1 (en) 2020-01-23
KR101308087B1 (ko) 2013-10-16
US20210347879A1 (en) 2021-11-11
HUE058876T2 (hu) 2022-09-28
ES2527428T3 (es) 2015-01-23
EP2468773A2 (en) 2012-06-27
US20090053213A1 (en) 2009-02-26
NZ564027A (en) 2011-06-30
AU2006249062B2 (en) 2012-12-20
BRPI0610796B1 (pt) 2020-01-21
EP1888643A2 (en) 2008-02-20
AU2006249062A1 (en) 2006-11-23
HRP20220755T3 (hr) 2022-09-02
JP2013116912A (ja) 2013-06-13
DK1888643T3 (en) 2015-01-05
AR053608A1 (es) 2007-05-09
EP3620171B1 (en) 2022-04-20
WO2006122797A3 (en) 2007-02-15
BRPI0610796B8 (pt) 2021-05-25
DK3620171T3 (da) 2022-06-07
PT1888643E (pt) 2015-01-14
PL3620171T3 (pl) 2022-08-08
EP2468773A3 (en) 2012-09-19
BRPI0610796A2 (pt) 2010-11-09
IL187375A0 (en) 2008-02-09
WO2006122797B1 (en) 2007-04-19
US9751939B2 (en) 2017-09-05
CN103087190A (zh) 2013-05-08
NO20076437L (no) 2007-12-13
JP2008545632A (ja) 2008-12-18
CA2608498A1 (en) 2006-11-23
ES2918209T3 (es) 2022-07-14
CY1115920T1 (el) 2017-01-25
EP3150221A1 (en) 2017-04-05
IL187375A (en) 2012-06-28
RS63382B1 (sr) 2022-08-31
KR20080015008A (ko) 2008-02-15
WO2006122797A2 (en) 2006-11-23
RS53743B1 (sr) 2015-06-30
SI3620171T1 (sl) 2022-09-30
US20110045000A1 (en) 2011-02-24
EP3620171A1 (en) 2020-03-11
RU2447085C2 (ru) 2012-04-10
ME02059B (me) 2015-05-20
US11028165B2 (en) 2021-06-08
HRP20150023T1 (hr) 2015-02-27
LT3620171T (lt) 2022-06-10
RU2007147870A (ru) 2009-06-27
SI1888643T1 (sl) 2015-03-31
TW200716674A (en) 2007-05-01
JP5295759B2 (ja) 2013-09-18
CA2608498C (en) 2017-04-04
NO344992B1 (no) 2020-08-17
CN103087190B (zh) 2016-08-03
US10377820B2 (en) 2019-08-13
HK1114620A1 (en) 2008-11-07
EP1888643B1 (en) 2014-10-29
CY1125427T1 (el) 2025-05-09
CN101218255B (zh) 2013-01-09

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