PL1858915T3 - Warianty wirusa zapalenia wątroby typu B oporne na pewne analogi nukleozydów ale wrażliwe na inne i ich zastosowania - Google Patents

Warianty wirusa zapalenia wątroby typu B oporne na pewne analogi nukleozydów ale wrażliwe na inne i ich zastosowania

Info

Publication number
PL1858915T3
PL1858915T3 PL06723428T PL06723428T PL1858915T3 PL 1858915 T3 PL1858915 T3 PL 1858915T3 PL 06723428 T PL06723428 T PL 06723428T PL 06723428 T PL06723428 T PL 06723428T PL 1858915 T3 PL1858915 T3 PL 1858915T3
Authority
PL
Poland
Prior art keywords
hepatitis
variants
sensitive
nucleoside analogues
resistant against
Prior art date
Application number
PL06723428T
Other languages
English (en)
Inventor
Oliver Schildgen
Martin Vogel
Bertfried Matz
Juergen Rockstroh
Rolf Kaiser
Martin Daeumer
Martin Helm
Lutwin Weitner
Carl Knud Schewe
Wolfram Gerlich
Original Assignee
Univ Bonn Rheinische Friedrich Wilhelms
Univ Koeln
Univ Justus Liebig Giessen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Bonn Rheinische Friedrich Wilhelms, Univ Koeln, Univ Justus Liebig Giessen filed Critical Univ Bonn Rheinische Friedrich Wilhelms
Publication of PL1858915T3 publication Critical patent/PL1858915T3/pl

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241Nucleotidyltransferases (2.7.7)
    • C12N9/1276RNA-directed DNA polymerase (2.7.7.49), i.e. reverse transcriptase or telomerase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/706Specific hybridization probes for hepatitis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5761Hepatitis B
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10121Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01DNA viruses
    • G01N2333/02Hepadnaviridae, e.g. hepatitis B virus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL06723428T 2005-03-15 2006-03-14 Warianty wirusa zapalenia wątroby typu B oporne na pewne analogi nukleozydów ale wrażliwe na inne i ich zastosowania PL1858915T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US66148305P 2005-03-15 2005-03-15
EP05102014 2005-03-15
PCT/EP2006/002351 WO2006097284A1 (en) 2005-03-15 2006-03-14 Variants of hepatitis b virus resistant against some nucleoside analogues, but sensitive to others, and uses thereof
EP06723428.6A EP1858915B1 (en) 2005-03-15 2006-03-14 Variants of hepatitis b virus resistant against some nucleoside analogues, but sensitive to others, and uses thereof

Publications (1)

Publication Number Publication Date
PL1858915T3 true PL1858915T3 (pl) 2015-01-30

Family

ID=35276399

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06723428T PL1858915T3 (pl) 2005-03-15 2006-03-14 Warianty wirusa zapalenia wątroby typu B oporne na pewne analogi nukleozydów ale wrażliwe na inne i ich zastosowania

Country Status (7)

Country Link
US (1) US7807437B2 (pl)
EP (1) EP1858915B1 (pl)
AU (1) AU2006224788B2 (pl)
ES (1) ES2470318T3 (pl)
PL (1) PL1858915T3 (pl)
PT (1) PT1858915E (pl)
WO (1) WO2006097284A1 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO351996A0 (en) * 1996-11-08 1996-12-05 Western Health Care Network Viral variants and methods for detecting same
USRE40233E1 (en) 1996-11-08 2008-04-08 Melbourne Health Viral variants and methods for detecting same
US7405039B2 (en) * 2002-02-07 2008-07-29 Austin Health Viral variants with altered susceptibility to nucleoside analogs and uses thereof
US8278432B2 (en) * 2002-03-29 2012-10-02 Innogenetics N.V. HBV drug resistance methods
WO2003087351A1 (en) 2002-04-12 2003-10-23 Melbourne Health Hepatitis b viral variants with redused susceptibility to nucleoside analogs and uses thereof
PT1858916E (pt) 2005-03-15 2014-10-06 Fujirebio Europ N V Variantes virais da hepatite b com uma susceptibilidade reduzida para análogos de nucleósidos e as suas utilizações
PL1858915T3 (pl) 2005-03-15 2015-01-30 Univ Bonn Rheinische Friedrich Wilhelms Warianty wirusa zapalenia wątroby typu B oporne na pewne analogi nukleozydów ale wrażliwe na inne i ich zastosowania
AU2006230802A1 (en) * 2005-04-08 2006-10-12 Austin Health Variants of hepatitis B virus with resistance to anti-viral nucleoside agents and applications thereof
EP1874923A4 (en) * 2005-04-08 2010-08-04 Melbourne Health VARIANTS OF THE HEPATITIS B VIRUS WITH RESISTANCE TO ANTIVIRAL NUCLEOSIDAGENTS AND APPLICATIONS THEREOF
US9682109B2 (en) 2005-10-21 2017-06-20 Abl Sa Antiviral resistance mutants and applications thereof
CN101548014B (zh) 2006-06-06 2012-07-04 墨尔本保健公司 抗病毒抗性突变的检测和应用
DE102007062962A1 (de) 2007-12-21 2009-06-25 Siemens Healthcare Diagnostics Products Gmbh Neue Oberflächen-Protein-Mutante des Hepatitis B Virus HBV surface Antigen (HBsAg)
US9963751B2 (en) 2015-11-24 2018-05-08 The Penn State Research Foundation Compositions and methods for identifying agents to reduce hepatitis B virus covalently closed circular DNA

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5595739A (en) 1993-05-07 1997-01-21 Abbott Laboratories Hepatitis B virus mutants, reagents and methods for detection
ZA973367B (en) 1996-04-19 1997-11-18 Innogenetics Nv Method for typing and detecting HBV.
AUPO351996A0 (en) * 1996-11-08 1996-12-05 Western Health Care Network Viral variants and methods for detecting same
JP2000270876A (ja) 1999-03-26 2000-10-03 Genome Science Laboratories Co Ltd B型肝炎ウイルス遺伝子の変異検出方法および検出キット
AUPP967999A0 (en) 1999-04-09 1999-05-06 North Western Health Care Network Viral variants
CN100497604C (zh) 2002-02-07 2009-06-10 墨尔本保健公司 对核苷类似物具有改变的敏感性的病毒变体及其应用
US8278432B2 (en) * 2002-03-29 2012-10-02 Innogenetics N.V. HBV drug resistance methods
WO2003087351A1 (en) * 2002-04-12 2003-10-23 Melbourne Health Hepatitis b viral variants with redused susceptibility to nucleoside analogs and uses thereof
US20040194155A1 (en) * 2002-10-01 2004-09-30 Gilead Sciences, Inc. HBV mutations associated with reduced susceptibility to adefovir
PT1858916E (pt) * 2005-03-15 2014-10-06 Fujirebio Europ N V Variantes virais da hepatite b com uma susceptibilidade reduzida para análogos de nucleósidos e as suas utilizações
PL1858915T3 (pl) 2005-03-15 2015-01-30 Univ Bonn Rheinische Friedrich Wilhelms Warianty wirusa zapalenia wątroby typu B oporne na pewne analogi nukleozydów ale wrażliwe na inne i ich zastosowania

Also Published As

Publication number Publication date
US7807437B2 (en) 2010-10-05
ES2470318T3 (es) 2014-06-23
AU2006224788A1 (en) 2006-09-21
WO2006097284A1 (en) 2006-09-21
EP1858915A1 (en) 2007-11-28
PT1858915E (pt) 2014-06-11
AU2006224788B2 (en) 2012-08-16
US20070042356A1 (en) 2007-02-22
EP1858915B1 (en) 2014-04-02

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