PL1778680T3 - Spirocykliczne pochodne cykloheksanu - Google Patents
Spirocykliczne pochodne cykloheksanuInfo
- Publication number
- PL1778680T3 PL1778680T3 PL05776804T PL05776804T PL1778680T3 PL 1778680 T3 PL1778680 T3 PL 1778680T3 PL 05776804 T PL05776804 T PL 05776804T PL 05776804 T PL05776804 T PL 05776804T PL 1778680 T3 PL1778680 T3 PL 1778680T3
- Authority
- PL
- Poland
- Prior art keywords
- spirocyclic cyclohexane
- cyclohexane derivatives
- compounds
- spirocyclic
- treat
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004039382A DE102004039382A1 (de) | 2004-08-13 | 2004-08-13 | Spirocyclische Cyclohexan-Derivate |
PCT/EP2005/008625 WO2006018184A2 (de) | 2004-08-13 | 2005-08-09 | Spirocyclische cyclohexan-derivate |
EP05776804A EP1778680B1 (de) | 2004-08-13 | 2005-08-09 | Spirocyclische cyclohexan-derivate |
Publications (1)
Publication Number | Publication Date |
---|---|
PL1778680T3 true PL1778680T3 (pl) | 2009-04-30 |
Family
ID=35457057
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL05776804T PL1778680T3 (pl) | 2004-08-13 | 2005-08-09 | Spirocykliczne pochodne cykloheksanu |
Country Status (11)
Country | Link |
---|---|
US (1) | US7776848B2 (pl) |
EP (1) | EP1778680B1 (pl) |
AT (1) | ATE410424T1 (pl) |
CY (1) | CY1108794T1 (pl) |
DE (2) | DE102004039382A1 (pl) |
DK (1) | DK1778680T3 (pl) |
ES (1) | ES2314695T3 (pl) |
PL (1) | PL1778680T3 (pl) |
PT (1) | PT1778680E (pl) |
SI (1) | SI1778680T1 (pl) |
WO (1) | WO2006018184A2 (pl) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102006019597A1 (de) | 2006-04-27 | 2007-10-31 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
DE102006033114A1 (de) * | 2006-07-18 | 2008-01-24 | Grünenthal GmbH | Spirocyclische Azaindol-Derivate |
AU2009204048B2 (en) | 2008-01-11 | 2013-08-01 | Albany Molecular Research, Inc. | (1-azinone) -substituted pyridoindoles as MCH antagonists |
AR071066A1 (es) | 2008-03-27 | 2010-05-26 | Gruenenthal Chemie | Derivados de (hetero) aril-ciclohexano |
MX2010010337A (es) | 2008-03-27 | 2010-10-07 | Gruenenthal Gmbh | Derivados de espiro(5.5)undecano. |
CL2009000732A1 (es) | 2008-03-27 | 2009-05-15 | Gruenethal Gmbh | Compuestos derivados de hidroximetil ciclohexilaminas sustituidos; composicion farmaceutica que contiene a dicho compuesto y sus uso como moduladores del receptor de opiodes u y el receptor orl-1 para tratar el dolor, ansiedad, depresion, epilepsia, alzheimer, abuso del alcohol, hipertension, anorexia, obesidad y diarrea. |
DK2260042T3 (da) | 2008-03-27 | 2011-10-31 | Gruenenthal Gmbh | Substituerede spirocykliske cyklohexan-derivater |
ES2663398T3 (es) | 2008-03-27 | 2018-04-12 | Grünenthal GmbH | Derivados de 4-aminociclohexano sustituidos |
WO2009118174A1 (de) | 2008-03-27 | 2009-10-01 | Grünenthal GmbH | Substituierte cyclohexyldiamine |
US8629158B2 (en) | 2009-07-01 | 2014-01-14 | Albany Molecular Research, Inc. | Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof |
US8637501B2 (en) | 2009-07-01 | 2014-01-28 | Albany Molecular Research, Inc. | Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine MCH-1 antagonists, methods of making, and use thereof |
US9073925B2 (en) | 2009-07-01 | 2015-07-07 | Albany Molecular Research, Inc. | Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof |
WO2011003012A1 (en) | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Azinone-substituted azapolycycle mch-1 antagonists, methods of making, and use thereof |
UA107943C2 (en) * | 2009-11-16 | 2015-03-10 | Lilly Co Eli | Compounds of spiropiperidines as antagonists of the orl-1 receptors |
DK2501704T3 (da) * | 2009-11-16 | 2013-10-14 | Lilly Co Eli | Spiropiperidinforbindelser som oral-1-receptorantagonister |
TWI582092B (zh) | 2010-07-28 | 2017-05-11 | 歌林達股份有限公司 | 順式-四氫-螺旋(環己烷-1,1’-吡啶[3,4-b]吲哚)-4-胺-衍生物 |
WO2012088124A2 (en) | 2010-12-21 | 2012-06-28 | Albany Molecular Research, Inc. | Tetrahydro-azacarboline mch-1 antagonists, methods of making, and uses thereof |
WO2012088038A2 (en) | 2010-12-21 | 2012-06-28 | Albany Molecular Research, Inc. | Piperazinone-substituted tetrahydro-carboline mch-1 antagonists, methods of making, and uses thereof |
TW201607923A (zh) | 2014-07-15 | 2016-03-01 | 歌林達有限公司 | 被取代之氮螺環(4.5)癸烷衍生物 |
CA2955071A1 (en) | 2014-07-15 | 2016-01-21 | Grunenthal Gmbh | Substituted azaspiro(4.5)decane derivatives |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1055203A (en) * | 1964-09-16 | 1967-01-18 | Ici Ltd | -ß-carboline derivatives, a process for their manufacture, and compositions containing them |
FR2663935A1 (fr) * | 1990-06-27 | 1992-01-03 | Adir | Nouveaux 1,2,3,4,5,6-hexahydroazepino [4,5-b] indoles et 1,2,3,4-tetrahydrobethacarbolines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. |
ATE229954T1 (de) * | 1998-06-12 | 2003-01-15 | Sod Conseils Rech Applic | Betacarbolinverbindungen |
CA2356269A1 (en) * | 1998-12-24 | 2000-07-06 | Yoshihisa Akiyama | Pain control agent |
DE10049481A1 (de) * | 2000-09-29 | 2002-05-02 | Gruenenthal Gmbh | Substituierte C-Cyclohexylmethylamin-Derivate |
DE10252667A1 (de) * | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
EP1633751A1 (en) * | 2003-06-16 | 2006-03-15 | Chroma Therapeutics Limited | Carboline and betacarboline derivatives for use as hdac enzyme inhibitors |
MXPA06003758A (es) * | 2003-10-02 | 2006-08-11 | Cephalon Inc | Derivados de indol substituido. |
-
2004
- 2004-08-13 DE DE102004039382A patent/DE102004039382A1/de not_active Withdrawn
-
2005
- 2005-08-09 PT PT05776804T patent/PT1778680E/pt unknown
- 2005-08-09 DE DE502005005636T patent/DE502005005636D1/de active Active
- 2005-08-09 SI SI200530533T patent/SI1778680T1/sl unknown
- 2005-08-09 ES ES05776804T patent/ES2314695T3/es active Active
- 2005-08-09 DK DK05776804T patent/DK1778680T3/da active
- 2005-08-09 EP EP05776804A patent/EP1778680B1/de not_active Expired - Fee Related
- 2005-08-09 PL PL05776804T patent/PL1778680T3/pl unknown
- 2005-08-09 WO PCT/EP2005/008625 patent/WO2006018184A2/de active Application Filing
- 2005-08-09 AT AT05776804T patent/ATE410424T1/de active
-
2007
- 2007-02-12 US US11/705,096 patent/US7776848B2/en not_active Expired - Fee Related
-
2008
- 2008-12-16 CY CY20081101451T patent/CY1108794T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP1778680B1 (de) | 2008-10-08 |
SI1778680T1 (sl) | 2009-02-28 |
WO2006018184A3 (de) | 2006-05-18 |
WO2006018184A2 (de) | 2006-02-23 |
DE102004039382A1 (de) | 2006-02-23 |
US20070213351A1 (en) | 2007-09-13 |
DE502005005636D1 (en) | 2008-11-20 |
PT1778680E (pt) | 2008-12-12 |
ATE410424T1 (de) | 2008-10-15 |
EP1778680A2 (de) | 2007-05-02 |
US7776848B2 (en) | 2010-08-17 |
DK1778680T3 (da) | 2008-12-15 |
CY1108794T1 (el) | 2014-04-09 |
ES2314695T3 (es) | 2009-03-16 |
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