PH9532A - Trifluoromethylmercapto-acetamidocephalosporins and composition thereof - Google Patents

Trifluoromethylmercapto-acetamidocephalosporins and composition thereof

Info

Publication number
PH9532A
PH9532A PH14825*UA PH14825A PH9532A PH 9532 A PH9532 A PH 9532A PH 14825 A PH14825 A PH 14825A PH 9532 A PH9532 A PH 9532A
Authority
PH
Philippines
Prior art keywords
acetamidocephalosporins
trifluoromethylmercapto
composition
Prior art date
Application number
PH14825*UA
Other languages
English (en)
Inventor
J Hoover
R Demarinis
Original Assignee
J Hoover
R Demarinis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by J Hoover, R Demarinis filed Critical J Hoover
Publication of PH9532A publication Critical patent/PH9532A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36Methylene radicals, substituted by sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/28Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an aliphatic carboxylic acid, which is substituted by hetero atoms
PH14825*UA 1972-07-20 1973-07-16 Trifluoromethylmercapto-acetamidocephalosporins and composition thereof PH9532A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00273571A US3828037A (en) 1972-07-20 1972-07-20 Trifluoromethylmercaptoacetamidocephalosporins

Publications (1)

Publication Number Publication Date
PH9532A true PH9532A (en) 1976-01-09

Family

ID=23044497

Family Applications (1)

Application Number Title Priority Date Filing Date
PH14825*UA PH9532A (en) 1972-07-20 1973-07-16 Trifluoromethylmercapto-acetamidocephalosporins and composition thereof

Country Status (24)

Country Link
US (1) US3828037A (xx)
JP (1) JPS5919959B2 (xx)
AR (1) AR197514A1 (xx)
AT (1) AT324562B (xx)
AU (1) AU467469B2 (xx)
BE (1) BE802199A (xx)
CA (1) CA1023347A (xx)
CH (1) CH584227A5 (xx)
CS (1) CS168037B2 (xx)
DD (1) DD114088A5 (xx)
DE (1) DE2336345C2 (xx)
ES (1) ES416980A1 (xx)
FI (1) FI57110C (xx)
FR (1) FR2193574B1 (xx)
GB (1) GB1393348A (xx)
HU (1) HU169129B (xx)
IE (1) IE37916B1 (xx)
IL (1) IL42737A (xx)
LU (1) LU68041A1 (xx)
NL (1) NL7309869A (xx)
PH (1) PH9532A (xx)
PL (1) PL85513B1 (xx)
SE (1) SE416205B (xx)
ZA (1) ZA734129B (xx)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE793448A (fr) * 1971-12-31 1973-06-28 Roussel Uclaf Procede de preparation de nouveaux derives des cephalosporines et produits obtenus
US3898220A (en) * 1972-07-20 1975-08-05 Smithkline Corp Trifluoromethylmercaptoacetamidocephalosporins
US3898221A (en) * 1972-07-20 1975-08-05 Smithkline Corp Trifluoromethylmercaptoacetamidocephalosporins
US3943128A (en) * 1973-06-18 1976-03-09 Smithkline Corporation 7-Trifluoromethylsulfinylacetamido cephalosporins
US3880848A (en) * 1973-06-18 1975-04-29 Smithkline Corp 7-Trifluorome thylsulfinylacetamido cephalosporins
US3943127A (en) * 1973-06-18 1976-03-09 Smithkline Corporation 7-Trifluoromethylsulfinylacetamido cephalosporins
US4013765A (en) * 1973-12-26 1977-03-22 Smithkline Corporation Compositions and methods for treating bacterial infections with substituted acetamidocephalosporins
US3998818A (en) * 1973-12-26 1976-12-21 Smithkline Corporation Trifluoroethylmercapto, -sulfinyl or -sulfonyl acetamidocephalosporins
US3957770A (en) * 1973-12-26 1976-05-18 Smithkline Corporation Substituted acetamidocephalosporins
US3998819A (en) * 1973-12-26 1976-12-21 Smithkline Corporation Trifluoroethyl-mercapto, -sulfinyl or -sulfonyl acetamidocephalosporins
US3907788A (en) * 1974-03-01 1975-09-23 American Home Prod Sulfenyl derivatives of 7-aminocephalosporanic acid
US3965099A (en) * 1974-06-26 1976-06-22 Smithkline Corporation Cephalosporin esters with antibacterial activity
US4286089A (en) * 1974-12-27 1981-08-25 Smithkline Corporation 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins
DK586175A (da) * 1974-12-28 1976-06-29 Asahi Chemical Ind Cephalosporin-forbindelser
US4093723A (en) * 1976-05-19 1978-06-06 Smithkline Corporation 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl) cephalosporins
US4020057A (en) * 1975-06-18 1977-04-26 Smithkline Corporation 7β-Acyloxy cephalosporins
US4025626A (en) * 1975-12-09 1977-05-24 Smithkline Corporation 7-Acyl-3-(ureidoalkyl substituted tetrazolylthiomethyl)-cephalosporins
US4075338A (en) * 1975-12-29 1978-02-21 Smithkline Corporation Substituted acetamidocephalosporins
US4041162A (en) * 1976-03-11 1977-08-09 Smithkline Corporation 7-Acyl-3-(sulfoalkyl substituted oxadiazolylthiomethyl) cephalosporins
US4034092A (en) * 1976-05-03 1977-07-05 Smithkline Corporation 7-Acyl-3-(carboxyalkyl and carbamoylalkyl substituted oxadiazolylthiomethyl) cephalosporins
US4058609A (en) * 1976-06-28 1977-11-15 Smithkline Corporation 7-Dithioacetamido cephalosporins
US4316016A (en) * 1979-03-19 1982-02-16 Bristol-Myers Company Cephalosporin intermediates
US4223135A (en) * 1979-03-19 1980-09-16 Bristol-Myers Company Production of cephalosporins
US4316017A (en) * 1979-03-19 1982-02-16 Bristol-Myers Company Cephalosporin intermediates
JPS57109761A (en) * 1980-12-26 1982-07-08 Shionogi & Co Ltd Fluoromethylthioacetic acid compound and its preparation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds

Also Published As

Publication number Publication date
BE802199A (fr) 1974-01-11
DD114088A5 (xx) 1975-07-12
HU169129B (xx) 1976-09-28
ES416980A1 (es) 1976-03-01
CH584227A5 (xx) 1977-01-31
SE416205B (sv) 1980-12-08
IL42737A (en) 1977-03-31
DE2336345A1 (de) 1974-02-07
AR197514A1 (es) 1974-04-15
FI57110C (fi) 1980-06-10
CS168037B2 (xx) 1976-05-28
AT324562B (de) 1975-09-10
FR2193574A1 (xx) 1974-02-22
JPS4943997A (xx) 1974-04-25
AU467469B2 (en) 1975-12-04
AU5831473A (en) 1975-01-23
JPS5919959B2 (ja) 1984-05-09
FI57110B (fi) 1980-02-29
DE2336345C2 (de) 1982-05-13
CA1023347A (en) 1977-12-27
ZA734129B (en) 1974-05-29
FR2193574B1 (xx) 1977-07-15
IE37916B1 (en) 1977-11-09
PL85513B1 (xx) 1976-04-30
GB1393348A (en) 1975-05-07
US3828037A (en) 1974-08-06
NL7309869A (xx) 1974-01-22
IL42737A0 (en) 1973-10-25
LU68041A1 (xx) 1973-09-26
IE37916L (en) 1974-01-20

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