PH21087A - Dibenzodiazepin derivatives and process for their preparation - Google Patents

Dibenzodiazepin derivatives and process for their preparation

Info

Publication number
PH21087A
PH21087A PH30678A PH30678A PH21087A PH 21087 A PH21087 A PH 21087A PH 30678 A PH30678 A PH 30678A PH 30678 A PH30678 A PH 30678A PH 21087 A PH21087 A PH 21087A
Authority
PH
Philippines
Prior art keywords
dibenzodiazepin
derivatives
preparation
dibenzodiazepin derivatives
Prior art date
Application number
PH30678A
Other languages
English (en)
Inventor
Edward J Glamkowski
Ching Yulin
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of PH21087A publication Critical patent/PH21087A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C07D215/06Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
PH30678A 1983-05-18 1984-05-16 Dibenzodiazepin derivatives and process for their preparation PH21087A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/495,569 US4761411A (en) 1983-05-18 1983-05-18 Dihydrobenzopyrrolobenzodiazepines useful for treating pyschoses

Publications (1)

Publication Number Publication Date
PH21087A true PH21087A (en) 1987-07-16

Family

ID=23969143

Family Applications (1)

Application Number Title Priority Date Filing Date
PH30678A PH21087A (en) 1983-05-18 1984-05-16 Dibenzodiazepin derivatives and process for their preparation

Country Status (16)

Country Link
US (1) US4761411A (da)
EP (1) EP0129692A3 (da)
JP (1) JPS59219285A (da)
KR (1) KR840009310A (da)
AU (1) AU575830B2 (da)
CA (1) CA1244414A (da)
DK (1) DK246984A (da)
ES (1) ES532509A0 (da)
FI (1) FI77865C (da)
GR (1) GR82273B (da)
HU (1) HU193010B (da)
IL (1) IL71856A0 (da)
NZ (1) NZ208180A (da)
PH (1) PH21087A (da)
PT (1) PT78599B (da)
ZA (1) ZA843722B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751223A (en) * 1986-10-14 1988-06-14 Hoechst-Roussel Pharmaceuticals, Inc. Antiinflammatory and analgesic aminoalkyl tetracyclic benzodiazepines
US4840947A (en) * 1986-10-14 1989-06-20 Hoechst-Roussel Pharmaceuticals, Inc. Antiinflammatory and analgesic piperidin-4-yl-tetracyclic benzodiazepines and use thereas
US5008262A (en) * 1988-04-19 1991-04-16 The United States Of America As Represented By The Department Of Health And Human Services Method of treating trichotillomania and onchyphagia
US4929615A (en) * 1989-06-12 1990-05-29 Hoechst-Roussel Pharmaceuticals Inc. 7H-benzo[b]pyrazino[1,2-d]pyrrolo[3,2,1-jk][1,4]benzodiazepines
US5312819A (en) * 1990-08-20 1994-05-17 Sandoz Ltd. Pharmaceutical compositions comprising clozapine and a radical scavenger
US6043358A (en) 1995-11-01 2000-03-28 Merck & Co., Inc. Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
CA2234641A1 (en) * 1995-11-01 1997-05-09 Merck & Co., Inc. Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
US7550499B2 (en) 2004-05-12 2009-06-23 Bristol-Myers Squibb Company Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
MX2007008434A (es) 2005-01-19 2007-07-25 Squibb Bristol Myers Co Derivados de 2-fenoxi-n-(1,3,4-tiadizol-2il)piridin-3-amina y compuestos relacionados como inhibidores del receptor p2y1 para el tratamiento de trastornos tromboembolicos.
WO2007002634A1 (en) 2005-06-27 2007-01-04 Bristol-Myers Squibb Company Carbocycle and heterocycle antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
AU2006261828A1 (en) 2005-06-27 2007-01-04 Bristol-Myers Squibb Company N-linked heterocyclic antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
EP1896417B1 (en) 2005-06-27 2011-03-23 Bristol-Myers Squibb Company Linear urea mimics antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
DE602006017694D1 (de) 2005-06-27 2010-12-02 Bristol Myers Squibb Co C-verknüpfte zyklische antagonisten des p2y1-rezeptors mit eignung bei der behandlung thrombotischer leiden
US7960569B2 (en) 2006-10-17 2011-06-14 Bristol-Myers Squibb Company Indole antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
US9453021B2 (en) 2011-05-10 2016-09-27 Kyowa Hakko Kirin Co., Ltd. Pyrimidodiazepinone compound

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2733371A (en) * 1970-04-14 1972-10-12 A. H. Robins Company, Incorporated 5, 7-DISUBSTITUTED-l, 9-ALKYLENE-l, 4-BENZODIAZEPIN-2 ONES
GB1451389A (en) * 1974-07-03 1976-09-29 Pierrel Spa Indolobenzazepines
US4192874A (en) * 1978-11-02 1980-03-11 American Hoechst Corporation Substituted 1,2,6,7-tetrahydroindolo[1,7-ab][1,5]benzodiazepines
US4186199A (en) * 1978-11-02 1980-01-29 American Hoechst Corporation Indolo-,1,2-dihydroindolo-, and 1,2,6,7-tetrahydroindolo [1,7-ab][1,5] benzodiazepines
IE57646B1 (en) * 1983-12-16 1993-02-10 Wyeth John & Brother Ltd Derivatives of imidazoquinolines and analogues thereof
GB8333581D0 (en) * 1983-12-16 1984-01-25 Wyeth John & Brother Ltd Heterocyclic compounds

Also Published As

Publication number Publication date
NZ208180A (en) 1988-01-08
ES8506652A1 (es) 1985-08-01
US4761411A (en) 1988-08-02
AU575830B2 (en) 1988-08-11
EP0129692A2 (en) 1985-01-02
HUT37432A (en) 1985-12-28
AU2834784A (en) 1984-11-22
FI841965A0 (fi) 1984-05-16
GR82273B (da) 1984-12-13
FI77865B (fi) 1989-01-31
FI77865C (fi) 1989-05-10
PT78599A (en) 1984-06-01
CA1244414A (en) 1988-11-08
HU193010B (en) 1987-08-28
PT78599B (en) 1986-07-17
FI841965A (fi) 1984-11-19
ES532509A0 (es) 1985-08-01
EP0129692A3 (en) 1987-07-29
JPS59219285A (ja) 1984-12-10
IL71856A0 (en) 1984-09-30
KR840009310A (ko) 1984-12-26
DK246984A (da) 1984-11-19
ZA843722B (en) 1985-01-30
DK246984D0 (da) 1984-05-17

Similar Documents

Publication Publication Date Title
DE3470737D1 (en) 2-aminonitropyridine derivatives and process for the preparation thereof
IL73190A0 (en) Cephalosporin derivatives and processes for their preparation
PH19919A (en) Macrocin derivatives and process for their preparation
PH21087A (en) Dibenzodiazepin derivatives and process for their preparation
ZA832385B (en) Substituted penem derivatives and process for their preparation
DE3479494D1 (en) Prostacyclines and process for their preparation
DE3471943D1 (en) Aminogroup containing phenol-novolaks and process for their preparation
DE3166969D1 (en) 6-quinazolinesulfonyl derivatives and process for preparation thereof
ZA849985B (en) Gonadoliberin derivatives and process for the preparation thereof
PT78916B (en) Formamidoxime derivatives preparation process
ZA847825B (en) Caphalosporin derivatives and processes for their preparations
ZA846580B (en) 16-fluoro-16,17-didehydro-prostanoids and process for their preparation
GB2146329B (en) Naphthalenylimidazopyridine and derivatives and their preparation
DE3476381D1 (en) Process for the preparation of pentadienol derivatives
DE3466685D1 (en) Process for preparing 3-phenoxy-1-azetidines and carboxamide derivatives
DE3364995D1 (en) Thiophene-2-carboxylic-acid derivatives and process for their preparation
GB2146028B (en) Spf-100 and process for the preparation thereof
DE3264631D1 (en) 4-halogenostilbene derivatives and process for their preparation
GB2071655B (en) N-amidazolyl derivatives of1-chroman and process for their preparation
IL67581A (en) Aminopropylaminobleomycin derivatives and process for preparation thereof
PL249198A1 (en) Process for preparing n-phosphonmethylglycine and its derivatives
DE3470541D1 (en) Tetrahydro-beta-carboline derivatives and process for the preparation thereof
GB2145722B (en) Process for the preparation of 6-demethyl-6-deoxy-6-methylene-5-oxytetracyclin and the 11a-chloro-derivative thereof
EP0123719A3 (en) 5-acyloxymethyloxazolidin-2-one derivative and process for preparing the same
IL68812A (en) Trans-d1-1-alkyl-6-alkoxy-octahydroquinolines and process for their preparation