PH20032A - Crystallization of ibuprofen - Google Patents

Crystallization of ibuprofen

Info

Publication number
PH20032A
PH20032A PH30294A PH30294A PH20032A PH 20032 A PH20032 A PH 20032A PH 30294 A PH30294 A PH 30294A PH 30294 A PH30294 A PH 30294A PH 20032 A PH20032 A PH 20032A
Authority
PH
Philippines
Prior art keywords
ibuprofen
crystallization
Prior art date
Application number
PH30294A
Other languages
English (en)
Inventor
Roger Eugene Gordon
Sanjay Indubhai Amin
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of PH20032A publication Critical patent/PH20032A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
PH30294A 1983-02-28 1984-02-24 Crystallization of ibuprofen PH20032A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47082083A 1983-02-28 1983-02-28
US06/517,116 US4476248A (en) 1983-02-28 1983-07-25 Crystallization of ibuprofen

Publications (1)

Publication Number Publication Date
PH20032A true PH20032A (en) 1986-09-04

Family

ID=27043233

Family Applications (1)

Application Number Title Priority Date Filing Date
PH30294A PH20032A (en) 1983-02-28 1984-02-24 Crystallization of ibuprofen

Country Status (10)

Country Link
US (1) US4476248A (es)
EP (1) EP0120587B1 (es)
JP (1) JPH0623126B2 (es)
KR (1) KR900003298B1 (es)
AU (1) AU567125B2 (es)
CA (1) CA1212693A (es)
DE (1) DE3460098D1 (es)
ES (1) ES530082A0 (es)
MX (1) MX161333A (es)
PH (1) PH20032A (es)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
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GB8606762D0 (en) * 1986-03-19 1986-04-23 Boots Co Plc Therapeutic agents
US5015646A (en) * 1987-08-28 1991-05-14 Bristol-Myers Squibb Co. Pharmaceutically useful polymorphic modification of buspirone
US4810789A (en) * 1987-08-28 1989-03-07 Bristol-Myers Company Process for buspirone hydrochloride polymorphic crystalline form conversion
SE463541B (sv) 1987-08-31 1990-12-10 Lejus Medical Ab Granulaer produkt oeverdragen av en smaelta av sig sjaelv samt foerfarande foer dess framstaellning
ATE121619T1 (de) * 1990-04-11 1995-05-15 Upjohn Co Verfahren zum geschmacksabdecken von ibuprofen.
US5151551A (en) * 1990-09-06 1992-09-29 Hoechst Celanese Corporation Method for purification of ibuprofen comprising mixtures
WO1992008686A1 (en) * 1990-11-19 1992-05-29 Ethyl Corporation Process for improving flow characteristics of crystalline ibuprofen
US5191114A (en) * 1991-10-09 1993-03-02 Sage Pharmaceuticals, Inc. Process for enhancing the flow characteristics of ibuprofen
US5300301A (en) * 1992-12-02 1994-04-05 Hoechst Celanese Corporation Isolation of ibuprofen from tablets
AT401871B (de) * 1994-01-28 1996-12-27 Gebro Broschek Gmbh Verfahren zur herstellung von s(+)-ibuprofen- partikeln mit verbesserten fliesseigenschaften und deren verwendung zur arzneimittelherstellung
US5608048A (en) * 1995-06-05 1997-03-04 Bristol-Myers Squibb Company d4 T polymorphic Form 1 process
US5922695A (en) * 1996-07-26 1999-07-13 Gilead Sciences, Inc. Antiviral phosphonomethyoxy nucleotide analogs having increased oral bioavarilability
GB2315661B (en) * 1996-07-26 2000-05-03 Unilever Plc Frozen food product
TR199902202T2 (xx) * 1997-03-14 1999-12-21 Unilever N.V. Dondurulmu� g�da �r�n�.
US5935946A (en) * 1997-07-25 1999-08-10 Gilead Sciences, Inc. Nucleotide analog composition and synthesis method
ZA986614B (en) 1997-07-25 1999-01-27 Gilead Sciences Nucleotide analog composition
FI122018B (fi) * 2000-01-31 2011-07-29 Danisco Menetelmä betaiinin kiteyttämiseksi
HRP20000328A2 (en) * 2000-05-19 2002-02-28 Pliva Farmaceutska Ind Dionik Novel polymorph v of torasemide
CA2788498C (en) * 2001-03-01 2016-02-16 Gilead Sciences, Inc. Polymorphic and other crystalline forms of cis-ftc
PL367262A1 (en) * 2001-04-26 2005-02-21 Bristol-Myers Squibb Company A pharmaceutical tablet having a high api content
DE10153934A1 (de) * 2001-11-06 2003-05-22 Basf Ag Verfahren zur Kristallisation von Profenen
DE602004014470D1 (de) 2003-01-14 2008-07-31 Gilead Sciences Inc Zusammensetzungen und verfahren zur antiviralen kombinationstherapie
ATE442352T1 (de) * 2003-05-16 2009-09-15 Cephalon France Verfahren zur herstellung von modafinil
FR2857253B1 (fr) * 2003-07-07 2007-02-09 Ethypharm Sa Installation comprenant une machine de fabrication de comprimes en particulier a usage therapeuthique
US20050137262A1 (en) * 2003-12-22 2005-06-23 Hu Patrick C. Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses
US20080247582A1 (en) 2004-09-09 2008-10-09 Guenther Godehard A Loudspeaker and Systems
TWI375560B (en) 2005-06-13 2012-11-01 Gilead Sciences Inc Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
CL2007002425A1 (es) * 2006-08-22 2008-06-27 Albermarle Corp Procedimiento de preparacion controlado de sal sodica de ibuprofeno de tamano de particula mediano; y dichas particulas de sal sodica.
US8189840B2 (en) 2007-05-23 2012-05-29 Soundmatters International, Inc. Loudspeaker and electronic devices incorporating same
JP2011500724A (ja) * 2007-10-19 2011-01-06 パーデュ リサーチ ファンデーション 結晶性化合物の固体製剤
EP2445486B1 (en) * 2009-06-22 2017-11-08 Wyeth LLC Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
CN103221391B (zh) 2010-01-27 2018-07-06 艾尼纳制药公司 (R)-2-(7-(4-环戊基-3-(三氟甲基)苄基氧基)-1,2,3,4-四氢环戊二烯并[b]吲哚-3-基)乙酸及其盐的制备方法
JP5821247B2 (ja) * 2010-04-07 2015-11-24 大正製薬株式会社 イブプロフェンの昇華抑制方法
CN102311335B (zh) * 2010-06-29 2013-12-11 山东新华制药股份有限公司 高松密度布洛芬的制备工艺
KR101324862B1 (ko) * 2011-07-12 2013-11-01 (주)에이에스텍 클로피도그렐 황산수소염의 구형 입자, 이를 포함하는 약학적 조성물 및 이의 제조방법
CN102936194A (zh) * 2012-11-14 2013-02-20 陕西合成药业有限公司 一种高纯度的布洛芬的精制方法
US10301262B2 (en) 2015-06-22 2019-05-28 Arena Pharmaceuticals, Inc. Crystalline L-arginine salt of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta [b]indol-3-yl)acetic acid(Compund1) for use in SIPI receptor-associated disorders
EP3582772A1 (en) 2017-02-16 2019-12-25 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
MA47503A (fr) 2017-02-16 2021-04-21 Arena Pharm Inc Composés et méthodes pour le traitement de maladies inflammatoires chroniques de l'intestin avec manifestations extra-intestinales
CN113200846B (zh) * 2021-04-23 2022-04-22 浙江新和成股份有限公司 一种高松密度布洛芬球形晶体的制备方法及其产品

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB971700A (en) * 1961-02-02 1964-09-30 Boots Pure Drug Co Ltd Anti-Inflammatory Agents
IT1059677B (it) * 1974-03-22 1982-06-21 Neopharmed Spa Sale di lisina ad azione terapeutica
JPS553336B2 (es) * 1974-04-11 1980-01-24
CA1062721A (en) * 1975-12-15 1979-09-18 Anthony A. Sinkula Propionic acid derivatives
US4189596A (en) * 1976-05-24 1980-02-19 The Upjohn Company Preparing 2-arylalkanoic acid derivatives

Also Published As

Publication number Publication date
JPS59167536A (ja) 1984-09-21
EP0120587A1 (en) 1984-10-03
KR840007554A (ko) 1984-12-08
MX161333A (es) 1990-09-10
ES8504658A1 (es) 1985-05-01
AU2377184A (en) 1984-09-06
CA1212693A (en) 1986-10-14
AU567125B2 (en) 1987-11-12
ES530082A0 (es) 1985-05-01
JPH0623126B2 (ja) 1994-03-30
US4476248A (en) 1984-10-09
DE3460098D1 (en) 1986-05-28
KR900003298B1 (ko) 1990-05-14
EP0120587B1 (en) 1986-04-23

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