ES530082A0 - Procedimiento para preparar ibuprofen cristalino - Google Patents

Procedimiento para preparar ibuprofen cristalino

Info

Publication number
ES530082A0
ES530082A0 ES530082A ES530082A ES530082A0 ES 530082 A0 ES530082 A0 ES 530082A0 ES 530082 A ES530082 A ES 530082A ES 530082 A ES530082 A ES 530082A ES 530082 A0 ES530082 A0 ES 530082A0
Authority
ES
Spain
Prior art keywords
procedure
preparing crystalline
crystalline ibuprofen
ibuprofen
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES530082A
Other languages
English (en)
Other versions
ES8504658A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of ES8504658A1 publication Critical patent/ES8504658A1/es
Publication of ES530082A0 publication Critical patent/ES530082A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
ES530082A 1983-02-28 1984-02-27 Procedimiento para preparar ibuprofen cristalino Granted ES530082A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47082083A 1983-02-28 1983-02-28
US06/517,116 US4476248A (en) 1983-02-28 1983-07-25 Crystallization of ibuprofen

Publications (2)

Publication Number Publication Date
ES8504658A1 ES8504658A1 (es) 1985-05-01
ES530082A0 true ES530082A0 (es) 1985-05-01

Family

ID=27043233

Family Applications (1)

Application Number Title Priority Date Filing Date
ES530082A Granted ES530082A0 (es) 1983-02-28 1984-02-27 Procedimiento para preparar ibuprofen cristalino

Country Status (10)

Country Link
US (1) US4476248A (es)
EP (1) EP0120587B1 (es)
JP (1) JPH0623126B2 (es)
KR (1) KR900003298B1 (es)
AU (1) AU567125B2 (es)
CA (1) CA1212693A (es)
DE (1) DE3460098D1 (es)
ES (1) ES530082A0 (es)
MX (1) MX161333A (es)
PH (1) PH20032A (es)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8606762D0 (en) * 1986-03-19 1986-04-23 Boots Co Plc Therapeutic agents
US4810789A (en) * 1987-08-28 1989-03-07 Bristol-Myers Company Process for buspirone hydrochloride polymorphic crystalline form conversion
US5015646A (en) * 1987-08-28 1991-05-14 Bristol-Myers Squibb Co. Pharmaceutically useful polymorphic modification of buspirone
SE463541B (sv) 1987-08-31 1990-12-10 Lejus Medical Ab Granulaer produkt oeverdragen av en smaelta av sig sjaelv samt foerfarande foer dess framstaellning
AU639988B2 (en) * 1990-04-11 1993-08-12 Pharmacia & Upjohn Company Taste masking of ibuprofen by fluid bed coating
US5151551A (en) * 1990-09-06 1992-09-29 Hoechst Celanese Corporation Method for purification of ibuprofen comprising mixtures
JP3167327B2 (ja) * 1990-11-19 2001-05-21 アルベマール・コーポレーシヨン 結晶性イブプロフェンの流れ特性を改良する方法
US5191114A (en) * 1991-10-09 1993-03-02 Sage Pharmaceuticals, Inc. Process for enhancing the flow characteristics of ibuprofen
US5300301A (en) * 1992-12-02 1994-04-05 Hoechst Celanese Corporation Isolation of ibuprofen from tablets
AT401871B (de) * 1994-01-28 1996-12-27 Gebro Broschek Gmbh Verfahren zur herstellung von s(+)-ibuprofen- partikeln mit verbesserten fliesseigenschaften und deren verwendung zur arzneimittelherstellung
US5608048A (en) * 1995-06-05 1997-03-04 Bristol-Myers Squibb Company d4 T polymorphic Form 1 process
GB2315661B (en) * 1996-07-26 2000-05-03 Unilever Plc Frozen food product
US5922695A (en) * 1996-07-26 1999-07-13 Gilead Sciences, Inc. Antiviral phosphonomethyoxy nucleotide analogs having increased oral bioavarilability
ES2241130T3 (es) * 1997-03-14 2005-10-16 Unilever N.V. Producto alimenticio congelado que contiene peptidos anticongelantes.
US5935946A (en) * 1997-07-25 1999-08-10 Gilead Sciences, Inc. Nucleotide analog composition and synthesis method
ZA986614B (en) 1997-07-25 1999-01-27 Gilead Sciences Nucleotide analog composition
FI122018B (fi) * 2000-01-31 2011-07-29 Danisco Menetelmä betaiinin kiteyttämiseksi
HRP20000328A2 (en) * 2000-05-19 2002-02-28 Pliva Farmaceutska Ind Dionik Novel polymorph v of torasemide
EP1903041B1 (en) * 2001-03-01 2015-02-18 AbbVie Inc. Polymorphic and other crystalline forms of cis-FTC
CN1523981A (zh) * 2001-04-26 2004-08-25 ����˹�ж�-����˹˹������˾ 具有高api含量的药物片剂
DE10153934A1 (de) * 2001-11-06 2003-05-22 Basf Ag Verfahren zur Kristallisation von Profenen
PT1583542E (pt) 2003-01-14 2008-09-17 Gilead Sciences Inc Composições e métodos para terapia de combinação antiviral
EP1477476B1 (en) * 2003-05-16 2009-09-09 Cephalon France Modafinil synthesis process
FR2857253B1 (fr) * 2003-07-07 2007-02-09 Ethypharm Sa Installation comprenant une machine de fabrication de comprimes en particulier a usage therapeuthique
US20050137262A1 (en) * 2003-12-22 2005-06-23 Hu Patrick C. Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses
EP1790192A4 (en) 2004-09-09 2010-06-02 Godehard A Guenther SPEAKERS AND SYSTEMS
TWI375560B (en) * 2005-06-13 2012-11-01 Gilead Sciences Inc Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
CL2007002425A1 (es) * 2006-08-22 2008-06-27 Albermarle Corp Procedimiento de preparacion controlado de sal sodica de ibuprofeno de tamano de particula mediano; y dichas particulas de sal sodica.
US8189840B2 (en) 2007-05-23 2012-05-29 Soundmatters International, Inc. Loudspeaker and electronic devices incorporating same
US20100222311A1 (en) * 2007-10-19 2010-09-02 Purdue Research Foundation Solid formulations of crystalline compounds
WO2011005478A2 (en) * 2009-06-22 2011-01-13 Wyeth Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
EP3378854B1 (en) 2010-01-27 2022-12-21 Arena Pharmaceuticals, Inc. Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof
JP5821247B2 (ja) * 2010-04-07 2015-11-24 大正製薬株式会社 イブプロフェンの昇華抑制方法
CN102311335B (zh) * 2010-06-29 2013-12-11 山东新华制药股份有限公司 高松密度布洛芬的制备工艺
KR101324862B1 (ko) * 2011-07-12 2013-11-01 (주)에이에스텍 클로피도그렐 황산수소염의 구형 입자, 이를 포함하는 약학적 조성물 및 이의 제조방법
CN102936194A (zh) * 2012-11-14 2013-02-20 陕西合成药业有限公司 一种高纯度的布洛芬的精制方法
WO2016209809A1 (en) 2015-06-22 2016-12-29 Arena Pharmaceuticals, Inc. Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid(compound1) for use in sipi receptor-associated disorders
CA3053416A1 (en) 2017-02-16 2018-08-23 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of inflammatory bowel disease with extra-intestinal manifestations
MA47504A (fr) 2017-02-16 2019-12-25 Arena Pharm Inc Composés et méthodes de traitement de l'angiocholite biliaire primitive
CN113200846B (zh) * 2021-04-23 2022-04-22 浙江新和成股份有限公司 一种高松密度布洛芬球形晶体的制备方法及其产品

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB971700A (en) * 1961-02-02 1964-09-30 Boots Pure Drug Co Ltd Anti-Inflammatory Agents
IT1059677B (it) * 1974-03-22 1982-06-21 Neopharmed Spa Sale di lisina ad azione terapeutica
JPS5614654B2 (es) * 1974-04-11 1981-04-06
CA1062721A (en) * 1975-12-15 1979-09-18 Anthony A. Sinkula Propionic acid derivatives
US4189596A (en) * 1976-05-24 1980-02-19 The Upjohn Company Preparing 2-arylalkanoic acid derivatives

Also Published As

Publication number Publication date
JPS59167536A (ja) 1984-09-21
KR840007554A (ko) 1984-12-08
US4476248A (en) 1984-10-09
ES8504658A1 (es) 1985-05-01
DE3460098D1 (en) 1986-05-28
CA1212693A (en) 1986-10-14
PH20032A (en) 1986-09-04
KR900003298B1 (ko) 1990-05-14
MX161333A (es) 1990-09-10
AU2377184A (en) 1984-09-06
EP0120587A1 (en) 1984-10-03
AU567125B2 (en) 1987-11-12
EP0120587B1 (en) 1986-04-23
JPH0623126B2 (ja) 1994-03-30

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Legal Events

Date Code Title Description
PC1A Transfer granted
FD1A Patent lapsed

Effective date: 20041004