PH19715A - Antidepressant imidazolines and related compounds - Google Patents

Antidepressant imidazolines and related compounds

Info

Publication number
PH19715A
PH19715A PH30284A PH30284A PH19715A PH 19715 A PH19715 A PH 19715A PH 30284 A PH30284 A PH 30284A PH 30284 A PH30284 A PH 30284A PH 19715 A PH19715 A PH 19715A
Authority
PH
Philippines
Prior art keywords
imidazolines
antidepressant
related compounds
compounds
antidepressant imidazolines
Prior art date
Application number
PH30284A
Other languages
English (en)
Inventor
Denis Mahlon Bailey
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of PH19715A publication Critical patent/PH19715A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/58Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/18Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/34Monohydroxylic alcohols containing six-membered aromatic rings and other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/06Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PH30284A 1983-03-14 1984-02-23 Antidepressant imidazolines and related compounds PH19715A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/475,193 US4540705A (en) 1983-03-14 1983-03-14 Antidepressant imidazolines and related compounds

Publications (1)

Publication Number Publication Date
PH19715A true PH19715A (en) 1986-06-17

Family

ID=23886585

Family Applications (1)

Application Number Title Priority Date Filing Date
PH30284A PH19715A (en) 1983-03-14 1984-02-23 Antidepressant imidazolines and related compounds

Country Status (16)

Country Link
US (1) US4540705A (member.php)
EP (1) EP0125410A3 (member.php)
JP (1) JPS59193875A (member.php)
KR (1) KR900001216B1 (member.php)
AU (1) AU568839B2 (member.php)
CA (1) CA1215369A (member.php)
DK (1) DK112984A (member.php)
ES (1) ES530345A0 (member.php)
FI (1) FI840839A7 (member.php)
GR (1) GR81813B (member.php)
IL (1) IL70966A (member.php)
NO (1) NO840893L (member.php)
NZ (1) NZ207184A (member.php)
PH (1) PH19715A (member.php)
PT (1) PT78195B (member.php)
ZA (1) ZA841323B (member.php)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9016800D0 (en) * 1990-07-31 1990-09-12 Shell Int Research Tetrahydropyrimidine derivatives
US6559157B2 (en) 1997-10-02 2003-05-06 Daiichi Pharmaceutical Co., Ltd. Dihydronaphthalene compounds
ZA988954B (en) * 1997-10-02 1999-04-12 Snow Brand Milk Products Co Ltd Novel dihydronaphthalene compound and production process of the same
US6329369B1 (en) 1997-12-04 2001-12-11 Allergan Sales, Inc. Methods of treating pain and other conditions
US6841684B2 (en) 1997-12-04 2005-01-11 Allergan, Inc. Imidiazoles having reduced side effects
PT924209E (pt) * 1997-12-19 2003-08-29 Lilly Co Eli Compostos de imidazolina hipoglicemicos
EP1266897A3 (en) * 1997-12-19 2003-12-03 Eli Lilly And Company Hypoglycemic imidazoline compounds
US6410562B1 (en) 1998-12-18 2002-06-25 Eli Lilly And Company Hypoglycemic imidazoline compounds
FR2787451B1 (fr) * 1998-12-18 2001-01-26 Adir Nouveaux composes imidazoliniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2007085557A2 (en) * 2006-01-27 2007-08-02 F. Hoffmann-La Roche Ag Use of substituted 2-imidazole of imidazoline derivatives
ES2381589T3 (es) 2006-10-19 2012-05-29 F. Hoffmann-La Roche Ag Aminometil-4-imidazoles
EP2086959B1 (en) 2006-11-02 2011-11-16 F. Hoffmann-La Roche AG Substituted 2-imidazoles as modulators of the trace amine associated receptors
CN101535298A (zh) 2006-11-16 2009-09-16 弗·哈夫曼-拉罗切有限公司 取代的4-咪唑类化合物
CA2672617A1 (en) 2006-12-13 2008-06-19 F. Hoffmann-La Roche Ag Novel 2-imidazoles as ligands for trace amine associated receptors (taar)
US20080146523A1 (en) 2006-12-18 2008-06-19 Guido Galley Imidazole derivatives
US7582691B2 (en) * 2007-01-17 2009-09-01 Sabic Innovative Plastics Ip B.V. Poly(arylene ether) compositions and articles
UA98951C2 (ru) 2007-02-02 2012-07-10 Ф. Хоффманн-Ля Рош Аг 2-аминооксазолины и лекарственное средство, которое их содержит
JP5130305B2 (ja) 2007-02-15 2013-01-30 エフ.ホフマン−ラ ロシュ アーゲー Taar1リガンドとしての2−アミノオキサゾリン
CA2691082A1 (en) 2007-07-02 2009-01-08 F. Hoffmann-La Roche Ag 2 -imidazolines having a good affinity to the trace amine associated receptors (taars)
EP2173719A1 (en) 2007-07-03 2010-04-14 F. Hoffmann-Roche AG 4-imidazolines and their use as antidepressants
RU2010104632A (ru) 2007-07-27 2011-09-20 Ф.Хоффманн-Ля Рош Аг (Ch) 2-азетидинметанамины и 2-пирролидинметанамины в качестве лигандов taar
KR101167773B1 (ko) 2007-08-03 2012-07-24 에프. 호프만-라 로슈 아게 Taar1 리간드로서의 피리딘카복스아마이드 및 벤즈아마이드 유도체
US8242153B2 (en) 2008-07-24 2012-08-14 Hoffmann-La Roche Inc. 4,5-dihydro-oxazol-2YL derivatives
US8354441B2 (en) 2009-11-11 2013-01-15 Hoffmann-La Roche Inc. Oxazoline derivatives
US9452980B2 (en) 2009-12-22 2016-09-27 Hoffmann-La Roche Inc. Substituted benzamides
RS60825B1 (sr) 2016-03-17 2020-10-30 Hoffmann La Roche Aktivnost derivata 5-etiol-4-metil-pirazol-3-karboksamida kao agonista taar-a

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2731471A (en) * 1956-01-17 Nxg hi
US2161938A (en) * 1934-07-31 1939-06-13 Soc Of Chemical Ind Imidazolines
FR926661A (fr) * 1941-07-09 1947-10-08 Lovens Kemiske Fabrik V Aug Ko Méthyle-imidazolines substituées et leur procédé de préparation
GB757650A (en) * 1953-06-15 1956-09-19 Pfizer & Co C Improvements in or relating to substituted imidazolines and the preparation thereof
DE1150180B (de) * 1962-04-12 1963-06-12 Merck Ag E Mittel zur Vorbehandlung der Haut fuer die Rasur
GB1317514A (en) * 1970-11-30 1973-05-23 Erba Carlo Spa Imidazoline derivatives
US4085209A (en) * 1975-02-05 1978-04-18 Rohm And Haas Company Preparation and safening effect of 1-substituted imidazole metal salt complexes

Also Published As

Publication number Publication date
FI840839A7 (fi) 1984-09-15
ES8601907A1 (es) 1985-11-16
JPS59193875A (ja) 1984-11-02
NZ207184A (en) 1986-12-05
US4540705A (en) 1985-09-10
CA1215369A (en) 1986-12-16
NO840893L (no) 1984-09-17
GR81813B (member.php) 1984-12-12
DK112984D0 (da) 1984-02-28
ES530345A0 (es) 1985-11-16
ZA841323B (en) 1984-10-31
EP0125410A2 (en) 1984-11-21
PT78195A (en) 1984-04-01
IL70966A (en) 1987-08-31
AU568839B2 (en) 1988-01-14
AU2487784A (en) 1984-09-20
FI840839A0 (fi) 1984-03-02
KR840008327A (ko) 1984-12-14
KR900001216B1 (ko) 1990-02-28
PT78195B (en) 1986-04-24
DK112984A (da) 1984-09-15
IL70966A0 (en) 1984-05-31
EP0125410A3 (en) 1987-01-14

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