PH17946A - Alkoxy and alkylthio furoic acids and their use as hypolipidemic agents - Google Patents

Alkoxy and alkylthio furoic acids and their use as hypolipidemic agents

Info

Publication number
PH17946A
PH17946A PH15598A PH15598A PH17946A PH 17946 A PH17946 A PH 17946A PH 15598 A PH15598 A PH 15598A PH 15598 A PH15598 A PH 15598A PH 17946 A PH17946 A PH 17946A
Authority
PH
Philippines
Prior art keywords
alkylthio
alkoxy
hypolipidemic agents
furoic acids
furoic
Prior art date
Application number
PH15598A
Other languages
English (en)
Inventor
Roger Alan Parker
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of PH17946A publication Critical patent/PH17946A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PH15598A 1973-04-02 1974-03-08 Alkoxy and alkylthio furoic acids and their use as hypolipidemic agents PH17946A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/347,064 US4110351A (en) 1973-04-02 1973-04-02 Hypolipidemic agents RO- or RS- substituted furoic acids, esters and salts

Publications (1)

Publication Number Publication Date
PH17946A true PH17946A (en) 1985-02-11

Family

ID=23362171

Family Applications (1)

Application Number Title Priority Date Filing Date
PH15598A PH17946A (en) 1973-04-02 1974-03-08 Alkoxy and alkylthio furoic acids and their use as hypolipidemic agents

Country Status (13)

Country Link
US (2) US4110351A (ja)
JP (1) JPS5844668B2 (ja)
AU (1) AU473143B2 (ja)
BE (1) BE813040A (ja)
CA (1) CA1077051A (ja)
CH (1) CH593960A5 (ja)
DE (1) DE2414680C2 (ja)
FR (1) FR2223030B1 (ja)
GB (1) GB1413648A (ja)
NL (1) NL178967C (ja)
PH (1) PH17946A (ja)
SE (1) SE417512B (ja)
ZA (1) ZA741420B (ja)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4017514A (en) * 1975-06-16 1977-04-12 Richardson-Merrell Inc. Hypolipidemic agents
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
JPS621279U (ja) * 1985-06-17 1987-01-07
US4980371A (en) * 1988-12-21 1990-12-25 Merrell Dow Pharmaceuticals Antiretroviral furan ketones
US5665874A (en) * 1989-01-17 1997-09-09 John Hopkins University Cancer related antigen
US5759837A (en) * 1989-01-17 1998-06-02 John Hopkins University Chemotherapy for cancer by inhibiting the fatty acid biosynthetic pathway
US5759791A (en) * 1989-01-17 1998-06-02 The Johns Hopkins University Cancer related antigen
US5614551A (en) * 1994-01-24 1997-03-25 The Johns Hopkins University Inhibitors of fatty acid synthesis as antimicrobial agents
US5981575A (en) * 1996-11-15 1999-11-09 Johns Hopkins University, The Inhibition of fatty acid synthase as a means to reduce adipocyte mass
US6262118B1 (en) 1999-06-04 2001-07-17 Metabolex, Inc. Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia
US6624194B1 (en) 1999-06-04 2003-09-23 Metabolex, Inc. Use of (−) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia
US7576131B2 (en) * 1999-06-04 2009-08-18 Metabolex, Inc. Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia
US7199259B2 (en) * 2003-06-20 2007-04-03 Metabolex, Inc. Resolution of α-(phenoxy)phenylacetic acid derivatives
CA2567437A1 (en) * 2004-05-25 2005-12-08 Metabolex, Inc. Substituted triazoles as modulators of ppar and methods of their preparation
JP2008500358A (ja) * 2004-05-25 2008-01-10 メタボレックス インコーポレーティッド Ｐｐａｒのモジュレーターとしての、二環式の置換されたトリアゾール、およびこれらの調製方法
US7714131B2 (en) * 2005-09-23 2010-05-11 Metabolex, Inc. Process for the stereoselective preparation of (−)-halofenate and derivatives thereof
US20100204317A1 (en) * 2006-11-03 2010-08-12 Qlt Inc. Methods of treating dermatological disorders or conditions
CN105017187B (zh) * 2009-07-08 2017-10-24 德米拉(加拿大)公司 用于治疗皮肤病症或疾病状态的tofa类似物
AU2013203113B2 (en) * 2009-07-08 2015-03-26 Dermira (Canada), Inc. TOFA analogs useful in treating dermatological disorders or conditions
ES2742412T3 (es) 2015-02-05 2020-02-14 Dermira Inc Proceso de síntesis para la preparación de derivados del ácido 2-furoico
WO2019072478A1 (en) 2017-10-10 2019-04-18 Galderma Research & Development SPECIFIC ACETYL-COA CARBOXYLASE INHIBITORS FOR USE IN THE TREATMENT AND / OR PREVENTION OF ACNE
WO2024026012A1 (en) * 2022-07-29 2024-02-01 The Regents Of The University Of California Compositions and methods for treating metabolic disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3517050A (en) * 1966-10-03 1970-06-23 Merck & Co Inc Ester and amide derivative of (3-trifluoromethylphenoxy) (4 - halophenyl)acetic acid
US3716644A (en) * 1971-07-15 1973-02-13 American Cyanamid Co Hypolipidemic agents

Also Published As

Publication number Publication date
FR2223030A1 (ja) 1974-10-25
SE417512B (sv) 1981-03-23
DE2414680C2 (de) 1983-12-22
FR2223030B1 (ja) 1977-05-06
DE2414680A1 (de) 1974-10-17
ZA741420B (en) 1975-01-29
CA1077051A (en) 1980-05-06
GB1413648A (en) 1975-11-12
NL178967C (nl) 1986-06-16
CH593960A5 (ja) 1977-12-30
BE813040A (fr) 1974-07-15
JPS5844668B2 (ja) 1983-10-04
JPS49127963A (ja) 1974-12-07
NL7404425A (ja) 1974-10-04
US4146623A (en) 1979-03-27
AU473143B2 (en) 1976-06-17
NL178967B (nl) 1986-01-16
AU6640974A (en) 1975-09-11
US4110351A (en) 1978-08-29

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