BE813040A - Nouveaux acides et esters furoiques substitues utiles comme agents hypolipidemiants - Google Patents

Nouveaux acides et esters furoiques substitues utiles comme agents hypolipidemiants

Info

Publication number
BE813040A
BE813040A BE142627A BE142627A BE813040A BE 813040 A BE813040 A BE 813040A BE 142627 A BE142627 A BE 142627A BE 142627 A BE142627 A BE 142627A BE 813040 A BE813040 A BE 813040A
Authority
BE
Belgium
Prior art keywords
hypolipidemiting
agents
esters useful
new substitute
furoic acids
Prior art date
Application number
BE142627A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE813040A publication Critical patent/BE813040A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
BE142627A 1973-04-02 1974-03-29 Nouveaux acides et esters furoiques substitues utiles comme agents hypolipidemiants BE813040A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/347,064 US4110351A (en) 1973-04-02 1973-04-02 Hypolipidemic agents RO- or RS- substituted furoic acids, esters and salts

Publications (1)

Publication Number Publication Date
BE813040A true BE813040A (fr) 1974-07-15

Family

ID=23362171

Family Applications (1)

Application Number Title Priority Date Filing Date
BE142627A BE813040A (fr) 1973-04-02 1974-03-29 Nouveaux acides et esters furoiques substitues utiles comme agents hypolipidemiants

Country Status (13)

Country Link
US (2) US4110351A (fr)
JP (1) JPS5844668B2 (fr)
AU (1) AU473143B2 (fr)
BE (1) BE813040A (fr)
CA (1) CA1077051A (fr)
CH (1) CH593960A5 (fr)
DE (1) DE2414680C2 (fr)
FR (1) FR2223030B1 (fr)
GB (1) GB1413648A (fr)
NL (1) NL178967C (fr)
PH (1) PH17946A (fr)
SE (1) SE417512B (fr)
ZA (1) ZA741420B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4017514A (en) * 1975-06-16 1977-04-12 Richardson-Merrell Inc. Hypolipidemic agents
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
JPS621279U (fr) * 1985-06-17 1987-01-07
US4980371A (en) * 1988-12-21 1990-12-25 Merrell Dow Pharmaceuticals Antiretroviral furan ketones
US5665874A (en) * 1989-01-17 1997-09-09 John Hopkins University Cancer related antigen
US5759791A (en) * 1989-01-17 1998-06-02 The Johns Hopkins University Cancer related antigen
US5759837A (en) * 1989-01-17 1998-06-02 John Hopkins University Chemotherapy for cancer by inhibiting the fatty acid biosynthetic pathway
US5614551A (en) * 1994-01-24 1997-03-25 The Johns Hopkins University Inhibitors of fatty acid synthesis as antimicrobial agents
US5981575A (en) * 1996-11-15 1999-11-09 Johns Hopkins University, The Inhibition of fatty acid synthase as a means to reduce adipocyte mass
US6624194B1 (en) * 1999-06-04 2003-09-23 Metabolex, Inc. Use of (−) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia
US6262118B1 (en) 1999-06-04 2001-07-17 Metabolex, Inc. Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia
US7576131B2 (en) * 1999-06-04 2009-08-18 Metabolex, Inc. Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia
US7199259B2 (en) * 2003-06-20 2007-04-03 Metabolex, Inc. Resolution of α-(phenoxy)phenylacetic acid derivatives
WO2005115384A2 (fr) * 2004-05-25 2005-12-08 Metabolex, Inc. Triazoles substitués bicyliques comme modulateurs de ppar et méthodes de préparation
RU2006145872A (ru) * 2004-05-25 2008-06-27 Метаболекс, Инк. (Us) Замещенные триазолы в качестве модуляторов ppar и способы их получения
US7714131B2 (en) * 2005-09-23 2010-05-11 Metabolex, Inc. Process for the stereoselective preparation of (−)-halofenate and derivatives thereof
CA2668414C (fr) * 2006-11-03 2015-02-10 Qlt Inc. Procedes de traitement de troubles ou d'affections dermatologiques
AU2013203113B2 (en) * 2009-07-08 2015-03-26 Dermira (Canada), Inc. TOFA analogs useful in treating dermatological disorders or conditions
CN102482249B (zh) * 2009-07-08 2016-06-08 德米拉(加拿大)公司 用于治疗皮肤病症或疾病状态的tofa类似物
DK3253743T3 (da) 2015-02-05 2019-08-19 Dermira Inc Syntetisk fremgangsmåde til fremstilling af 2-furansyre-derivater
WO2019072478A1 (fr) 2017-10-10 2019-04-18 Galderma Research & Development Inhibiteurs spécifiques de l'acétyl-coa carboxylase destinés à être utilisé dans le traitement et/ou la prévention de l'acné
WO2024026012A1 (fr) * 2022-07-29 2024-02-01 The Regents Of The University Of California Compositions et méthodes pour le traitement de troubles métaboliques

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3517050A (en) * 1966-10-03 1970-06-23 Merck & Co Inc Ester and amide derivative of (3-trifluoromethylphenoxy) (4 - halophenyl)acetic acid
US3716644A (en) * 1971-07-15 1973-02-13 American Cyanamid Co Hypolipidemic agents

Also Published As

Publication number Publication date
FR2223030B1 (fr) 1977-05-06
AU473143B2 (en) 1976-06-17
JPS5844668B2 (ja) 1983-10-04
GB1413648A (en) 1975-11-12
JPS49127963A (fr) 1974-12-07
NL178967B (nl) 1986-01-16
NL7404425A (fr) 1974-10-04
CA1077051A (fr) 1980-05-06
NL178967C (nl) 1986-06-16
US4110351A (en) 1978-08-29
FR2223030A1 (fr) 1974-10-25
US4146623A (en) 1979-03-27
DE2414680C2 (de) 1983-12-22
DE2414680A1 (de) 1974-10-17
AU6640974A (en) 1975-09-11
SE417512B (sv) 1981-03-23
CH593960A5 (fr) 1977-12-30
ZA741420B (en) 1975-01-29
PH17946A (en) 1985-02-11

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: RICHARDSON MERRELL INC.

Effective date: 19940329