FR2223030B1 - - Google Patents
Info
- Publication number
- FR2223030B1 FR2223030B1 FR7410583A FR7410583A FR2223030B1 FR 2223030 B1 FR2223030 B1 FR 2223030B1 FR 7410583 A FR7410583 A FR 7410583A FR 7410583 A FR7410583 A FR 7410583A FR 2223030 B1 FR2223030 B1 FR 2223030B1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/347,064 US4110351A (en) | 1973-04-02 | 1973-04-02 | Hypolipidemic agents RO- or RS- substituted furoic acids, esters and salts |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2223030A1 FR2223030A1 (fr) | 1974-10-25 |
| FR2223030B1 true FR2223030B1 (fr) | 1977-05-06 |
Family
ID=23362171
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7410583A Expired FR2223030B1 (fr) | 1973-04-02 | 1974-03-27 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US4110351A (fr) |
| JP (1) | JPS5844668B2 (fr) |
| AU (1) | AU473143B2 (fr) |
| BE (1) | BE813040A (fr) |
| CA (1) | CA1077051A (fr) |
| CH (1) | CH593960A5 (fr) |
| DE (1) | DE2414680C2 (fr) |
| FR (1) | FR2223030B1 (fr) |
| GB (1) | GB1413648A (fr) |
| NL (1) | NL178967C (fr) |
| PH (1) | PH17946A (fr) |
| SE (1) | SE417512B (fr) |
| ZA (1) | ZA741420B (fr) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4017514A (en) * | 1975-06-16 | 1977-04-12 | Richardson-Merrell Inc. | Hypolipidemic agents |
| GB1565966A (en) * | 1976-08-04 | 1980-04-23 | Allen & Hanburys Ltd | Aminoalkyl furan derivatives |
| JPS621279U (fr) * | 1985-06-17 | 1987-01-07 | ||
| US4980371A (en) * | 1988-12-21 | 1990-12-25 | Merrell Dow Pharmaceuticals | Antiretroviral furan ketones |
| US5665874A (en) * | 1989-01-17 | 1997-09-09 | John Hopkins University | Cancer related antigen |
| US5759837A (en) * | 1989-01-17 | 1998-06-02 | John Hopkins University | Chemotherapy for cancer by inhibiting the fatty acid biosynthetic pathway |
| US5759791A (en) * | 1989-01-17 | 1998-06-02 | The Johns Hopkins University | Cancer related antigen |
| US5614551A (en) * | 1994-01-24 | 1997-03-25 | The Johns Hopkins University | Inhibitors of fatty acid synthesis as antimicrobial agents |
| US5981575A (en) * | 1996-11-15 | 1999-11-09 | Johns Hopkins University, The | Inhibition of fatty acid synthase as a means to reduce adipocyte mass |
| US6262118B1 (en) | 1999-06-04 | 2001-07-17 | Metabolex, Inc. | Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia |
| US6624194B1 (en) | 1999-06-04 | 2003-09-23 | Metabolex, Inc. | Use of (−) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia |
| US7576131B2 (en) * | 1999-06-04 | 2009-08-18 | Metabolex, Inc. | Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia |
| US7199259B2 (en) * | 2003-06-20 | 2007-04-03 | Metabolex, Inc. | Resolution of α-(phenoxy)phenylacetic acid derivatives |
| CA2567437A1 (fr) * | 2004-05-25 | 2005-12-08 | Metabolex, Inc. | Triazoles substitues comme modulateurs de ppar et methodes de preparation |
| JP2008500358A (ja) * | 2004-05-25 | 2008-01-10 | メタボレックス インコーポレーティッド | Ｐｐａｒのモジュレーターとしての、二環式の置換されたトリアゾール、およびこれらの調製方法 |
| US7714131B2 (en) * | 2005-09-23 | 2010-05-11 | Metabolex, Inc. | Process for the stereoselective preparation of (−)-halofenate and derivatives thereof |
| US20100204317A1 (en) * | 2006-11-03 | 2010-08-12 | Qlt Inc. | Methods of treating dermatological disorders or conditions |
| CN105017187B (zh) * | 2009-07-08 | 2017-10-24 | 德米拉(加拿大)公司 | 用于治疗皮肤病症或疾病状态的tofa类似物 |
| AU2013203113B2 (en) * | 2009-07-08 | 2015-03-26 | Dermira (Canada), Inc. | TOFA analogs useful in treating dermatological disorders or conditions |
| ES2742412T3 (es) | 2015-02-05 | 2020-02-14 | Dermira Inc | Proceso de síntesis para la preparación de derivados del ácido 2-furoico |
| WO2019072478A1 (fr) | 2017-10-10 | 2019-04-18 | Galderma Research & Development | Inhibiteurs spécifiques de l'acétyl-coa carboxylase destinés à être utilisé dans le traitement et/ou la prévention de l'acné |
| WO2024026012A1 (fr) * | 2022-07-29 | 2024-02-01 | The Regents Of The University Of California | Compositions et méthodes pour le traitement de troubles métaboliques |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3517050A (en) * | 1966-10-03 | 1970-06-23 | Merck & Co Inc | Ester and amide derivative of (3-trifluoromethylphenoxy) (4 - halophenyl)acetic acid |
| US3716644A (en) * | 1971-07-15 | 1973-02-13 | American Cyanamid Co | Hypolipidemic agents |
-
1973
- 1973-04-02 US US05/347,064 patent/US4110351A/en not_active Expired - Lifetime
-
1974
- 1974-03-05 ZA ZA00741420A patent/ZA741420B/xx unknown
- 1974-03-06 CA CA194,208A patent/CA1077051A/fr not_active Expired
- 1974-03-07 AU AU66409/74A patent/AU473143B2/en not_active Expired
- 1974-03-08 PH PH15598A patent/PH17946A/en unknown
- 1974-03-27 DE DE2414680A patent/DE2414680C2/de not_active Expired
- 1974-03-27 FR FR7410583A patent/FR2223030B1/fr not_active Expired
- 1974-03-27 JP JP49033635A patent/JPS5844668B2/ja not_active Expired
- 1974-03-28 GB GB1380674A patent/GB1413648A/en not_active Expired
- 1974-03-29 BE BE142627A patent/BE813040A/fr not_active IP Right Cessation
- 1974-04-01 SE SE7404352A patent/SE417512B/xx not_active IP Right Cessation
- 1974-04-01 NL NLAANVRAGE7404425,A patent/NL178967C/xx not_active IP Right Cessation
- 1974-04-02 CH CH461074A patent/CH593960A5/xx not_active IP Right Cessation
-
1978
- 1978-04-24 US US05/899,310 patent/US4146623A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FR2223030A1 (fr) | 1974-10-25 |
| SE417512B (sv) | 1981-03-23 |
| DE2414680C2 (de) | 1983-12-22 |
| DE2414680A1 (de) | 1974-10-17 |
| ZA741420B (en) | 1975-01-29 |
| PH17946A (en) | 1985-02-11 |
| CA1077051A (fr) | 1980-05-06 |
| GB1413648A (en) | 1975-11-12 |
| NL178967C (nl) | 1986-06-16 |
| CH593960A5 (fr) | 1977-12-30 |
| BE813040A (fr) | 1974-07-15 |
| JPS5844668B2 (ja) | 1983-10-04 |
| JPS49127963A (fr) | 1974-12-07 |
| NL7404425A (fr) | 1974-10-04 |
| US4146623A (en) | 1979-03-27 |
| AU473143B2 (en) | 1976-06-17 |
| NL178967B (nl) | 1986-01-16 |
| AU6640974A (en) | 1975-09-11 |
| US4110351A (en) | 1978-08-29 |