PE20220582A1 - Sensor y sistema de deteccion - Google Patents

Sensor y sistema de deteccion

Info

Publication number
PE20220582A1
PE20220582A1 PE2019002656A PE2019002656A PE20220582A1 PE 20220582 A1 PE20220582 A1 PE 20220582A1 PE 2019002656 A PE2019002656 A PE 2019002656A PE 2019002656 A PE2019002656 A PE 2019002656A PE 20220582 A1 PE20220582 A1 PE 20220582A1
Authority
PE
Peru
Prior art keywords
electrodes
polynucleotide chains
polynucleotide
modulable
nucleic acid
Prior art date
Application number
PE2019002656A
Other languages
English (en)
Inventor
John Moon
Original Assignee
Illumina Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina Inc filed Critical Illumina Inc
Publication of PE20220582A1 publication Critical patent/PE20220582A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nanotechnology (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Electrochemistry (AREA)
  • Evolutionary Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Burglar Alarm Systems (AREA)
  • Geophysics And Detection Of Objects (AREA)

Abstract

Un sensor incluye dos electrodos y un canal conductor de electricidad modulable unido a los dos electrodos. El canal electricamente conductor modulable incluye un polimero de acido nucleico parcialmente bicatenario, modificado, conectado electricamente a los dos electrodos y puenteando el espacio entre los dos electrodos. El polimero de acido nucleico parcialmente bicatenario modificado incluye dos cadenas de polinucleotidos parcialmente unidas entre si, un hueco en la primera de las cadenas de polinucleotidos en el que faltan bases de nucleotidos, y una pluralidad de bases de nucleotidos de una segunda de las cadenas de polinucleotidos expuesta en el hueco en la primera de las cadenas de polinucleotidos.
PE2019002656A 2018-06-29 2019-06-13 Sensor y sistema de deteccion PE20220582A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862692468P 2018-06-29 2018-06-29
NL2021376A NL2021376B1 (en) 2018-06-29 2018-07-23 Sensor and sensing system
PCT/US2019/036979 WO2020005557A1 (en) 2018-06-29 2019-06-13 Sensor and sensing system

Publications (1)

Publication Number Publication Date
PE20220582A1 true PE20220582A1 (es) 2022-04-20

Family

ID=67001730

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2019002656A PE20220582A1 (es) 2018-06-29 2019-06-13 Sensor y sistema de deteccion

Country Status (21)

Country Link
US (2) US11332786B2 (es)
EP (1) EP3587591B1 (es)
JP (1) JP7034185B2 (es)
KR (2) KR102530252B1 (es)
CN (2) CN212199257U (es)
AU (1) AU2019279958B2 (es)
BR (1) BR112019028107A2 (es)
CA (1) CA3064903C (es)
CL (1) CL2019003785A1 (es)
CO (1) CO2019014758A2 (es)
CR (1) CR20190589A (es)
IL (1) IL271292A (es)
MX (1) MX2019015851A (es)
NL (1) NL2021376B1 (es)
PE (1) PE20220582A1 (es)
PH (1) PH12019502904A1 (es)
RU (1) RU2747795C1 (es)
SG (1) SG11201913460RA (es)
TW (1) TWI699528B (es)
WO (1) WO2020005557A1 (es)
ZA (1) ZA201908277B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL2021376B1 (en) * 2018-06-29 2020-01-06 Illumina Inc Sensor and sensing system
US20240002928A1 (en) * 2020-04-21 2024-01-04 Roche Sequencing Solutions, Inc. High-throughput nucleic acid sequencing with single-molecule-sensor arrays
EP4146823A1 (en) * 2020-05-04 2023-03-15 Illumina, Inc. Compositions and methods for sequencing using polymer bridges
WO2022005395A1 (en) * 2020-06-30 2022-01-06 Illumina Singapore Pte. Ltd. Compositions and methods for sequencing using at least altering electrical characteristics of bridges between electrodes
CA3182087A1 (en) * 2020-06-30 2022-01-06 Illumina, Inc. Compositions and methods for sequencing using at least electrical characteristics
CN112525961A (zh) * 2020-10-28 2021-03-19 重庆第二师范学院 一种基于纳米复合材料的生物传感器及其构建方法
WO2022211905A1 (en) * 2021-03-30 2022-10-06 Illumina, Inc. Compositions and methods for sequencing using polymers with metal-coated regions and exposed regions
US20240094189A1 (en) 2021-03-31 2024-03-21 Illumina, Inc. Scalable circuit for molecular detection

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6706473B1 (en) * 1996-12-06 2004-03-16 Nanogen, Inc. Systems and devices for photoelectrophoretic transport and hybridization of oligonucleotides
US20030203394A1 (en) * 1998-05-04 2003-10-30 Yoav Eichen Detection of a target in a sample
JP4555484B2 (ja) 1999-04-07 2010-09-29 デニス マイケル コノリー 高解像度のｄｎａ検出の方法および装置
US7176482B1 (en) * 2000-11-28 2007-02-13 Ramot At Tel-Aviv University DNA-based electronics
US20020072054A1 (en) 2000-12-13 2002-06-13 The Regents Of The University Of California Sensor using impedance change to detect the end-point for PCR DNA amplification
DE10113550A1 (de) * 2001-03-20 2002-10-02 Infineon Technologies Ag Verfahren zum Erfassen von makromolekularen Biopolymeren mittels einer Elektrodenanordnung
US6824974B2 (en) * 2001-06-11 2004-11-30 Genorx, Inc. Electronic detection of biological molecules using thin layers
CA2450109A1 (en) * 2001-06-11 2003-05-22 Genorx, Inc. Electronic detection of biological molecules using thin layers
US7245370B2 (en) 2005-01-06 2007-07-17 Hewlett-Packard Development Company, L.P. Nanowires for surface-enhanced Raman scattering molecular sensors
TWI287041B (en) * 2005-04-27 2007-09-21 Jung-Tang Huang An ultra-rapid DNA sequencing method with nano-transistors array based devices
US8597492B2 (en) 2007-01-30 2013-12-03 The Florida International University Board Of Trustees Nanoscale DNA detection system using species-specific and/or disease-specific probes for rapid identification
AT505495A1 (de) 2007-07-04 2009-01-15 Arc Austrian Res Centers Gmbh Verfahren zur identifizierung und quantifizierung von organischen und biochemischen substanzen
US20120058470A1 (en) * 2009-05-13 2012-03-08 University Of Southern California Electrical wiring of polynucleotides for nanoelectronic applications
KR101220869B1 (ko) * 2010-01-05 2013-01-11 한국생명공학연구원 Ｄｎａ를 이용한 금속 나노와이어 제조 및 ｄｎａ 측정 방법
CN102384934A (zh) * 2011-09-23 2012-03-21 东南大学 在纳米孔表面制备纳米间隙电极的方法
KR101974577B1 (ko) 2012-05-21 2019-05-02 삼성전자주식회사 나노입자 제작용 주형 및 이를 이용한 나노입자의 제조 방법
WO2016010975A2 (en) * 2014-07-15 2016-01-21 Illumina, Inc. Biochemically activated electronic device
JP7166586B2 (ja) * 2015-06-25 2022-11-08 ロズウェル バイオテクノロジーズ，インコーポレイテッド 生体分子センサーおよび方法
CN115595360A (zh) * 2016-04-27 2023-01-13 因美纳剑桥有限公司（Gb） 用于生物分子的测量和测序的系统和方法
NL2021376B1 (en) * 2018-06-29 2020-01-06 Illumina Inc Sensor and sensing system

Also Published As

Publication number Publication date
JP2021501562A (ja) 2021-01-21
US20200002758A1 (en) 2020-01-02
CA3064903A1 (en) 2019-12-29
MX2019015851A (es) 2020-08-17
CA3064903C (en) 2023-07-25
JP7034185B2 (ja) 2022-03-11
KR20210135345A (ko) 2021-11-12
KR102530252B1 (ko) 2023-05-09
ZA201908277B (en) 2022-07-27
CN212199257U (zh) 2020-12-22
CN110656035A (zh) 2020-01-07
AU2019279958A1 (en) 2020-01-16
CL2019003785A1 (es) 2020-07-10
EP3587591B1 (en) 2022-10-05
US20220259650A1 (en) 2022-08-18
PH12019502904A1 (en) 2020-09-14
KR20200026214A (ko) 2020-03-10
SG11201913460RA (en) 2020-01-30
BR112019028107A2 (pt) 2020-07-14
IL271292A (en) 2020-01-30
CR20190589A (es) 2020-02-26
CO2019014758A2 (es) 2020-01-17
EP3587591A1 (en) 2020-01-01
US11332786B2 (en) 2022-05-17
RU2747795C1 (ru) 2021-05-14
TW202001237A (zh) 2020-01-01
TWI699528B (zh) 2020-07-21
AU2019279958B2 (en) 2022-03-10
NL2021376B1 (en) 2020-01-06
WO2020005557A1 (en) 2020-01-02

Similar Documents

Publication Publication Date Title
PE20220582A1 (es) Sensor y sistema de deteccion
ES2618728T3 (es) Sensores, interfaces y sistemas de sensores para la recolección de data y la integración del monitoreo remoto de condiciones cercanas o sobre las superficies del cuerpo
CY1124072T1 (el) Δομοστοιχειωτες μοναδες προστασιας απο υπερταση
EP4303314A3 (en) Polypeptide tagged nucleotides and use thereof in nucleic acid sequencing by nanopore detection
AR096706A1 (es) Conjunto conductor
EP2958000A3 (en) Touch panel and touch detection circuit
DE602008002429D1 (de) Elektrischer verbinder mit übersprechauslöschmerkmalen
PE20191676A1 (es) Montaje para medir la corriente electrica en un electrodo individual en un sistema de electrolisis
BR112017021192A2 (pt) lista de retransmissão ue-para-ue e determinação de arbitragem de acessibilidade
EA201790003A1 (ru) Гибридный гальванический элемент
GB2549164A (en) Detection of translocation events using graphene-based nanopore assemblies
EA201692178A1 (ru) Электрический соединительный элемент для контактирования электропроводной структуры на подложке
CO6511265A2 (es) Monitoreo de un medio de suspension y traccion de un sistema de ascensor
WO2012048168A3 (en) Analyte monitoring devices and methods
MX2016006191A (es) Montaje de sensores de proximidad que tiene una configuracion de electrodos intercalados.
BR112016018795A2 (pt) Nó b melhorado (enb), ue e método para selecionar sinais de detecção de células em redes lte
CL2016003415A1 (es) Un sensor y un sistema para monitorear la integridad de un sistema o membrana de impermeabilización
PE20151703A1 (es) Medicion de la corriente electrica en un electrodo individual en un sistema de electrolisis
CL2015001550A1 (es) Polïmeros electroactivas dieléctrica que comprenden una estructura iónica supramolecular.
CL2011002151A1 (es) Metodo y sistema para el monitoreo de la integridad de un conector.
WO2019014218A3 (en) SEQUENCING METHOD FOR DETECTION OF GENOMIC REARRANGEMENTS
BR112018009434A2 (pt) imageamento de resistividade usando sensores capacitivos e indutivos de combinação
FR3044962B1 (fr) Vitrage muni d'un dispositif conducteur electrique et possedant une resistance amelioree aux tests cycliques de temperature.
AR101784A1 (es) Un conector para bus serial con seguridad mejorada
BR102015017209A2 (pt) aparelho e método para a disposição de elementos de detecção de campo magnético em sensores