PE20050341A1 - Uso de antibioticos de quinolona y 8-ciano-quinolona - Google Patents

Uso de antibioticos de quinolona y 8-ciano-quinolona

Info

Publication number
PE20050341A1
PE20050341A1 PE2004000780A PE2004000780A PE20050341A1 PE 20050341 A1 PE20050341 A1 PE 20050341A1 PE 2004000780 A PE2004000780 A PE 2004000780A PE 2004000780 A PE2004000780 A PE 2004000780A PE 20050341 A1 PE20050341 A1 PE 20050341A1
Authority
PE
Peru
Prior art keywords
alkyl
quinolone
spp
cyano
antibiotics
Prior art date
Application number
PE2004000780A
Other languages
English (en)
Inventor
Gert Daube
Markus Edingloh
Agnes Limet
Bernd Stephan
Franz Pirro
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34201505&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20050341(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Publication of PE20050341A1 publication Critical patent/PE20050341A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

SE REFIERE AL USO DE (a) ANTIBIOTICOS DE 8-CIANO-QUINOLONA o (b) ANTIBIOTICOS DE QUINOLONA ELEGIDOS DEL GRUPO FORMADO POR: GARENOXACINA, MARBOFLOXACINA, IBAFLOXACINA, DANOFLOXACINA, DIFLOXACINA y ORBIFLOXACINA. DICHO ANTIBIOTICO DE 8-CIANO-QUINOLONA TIENE LA FORMULA I, EN LA QUE X ES H, HALOGENO, ALQUILO C1-C4, ALCOXI C1-C4 o NH2; R1 ES ALQUILO C1-C3, CICLOPROPILO, 2-FLUORETILO, ENTRE OTROS; R2 ES H o ALQUILO C1-C6; A ES =C(CN); Y ES UN RESTO SELECCIONADO DEL GRUPO a ENTRE OTROS; R4 ES ALQUILO C1-C4; R5 ES H, METILO, FENILO, TIENILO O PIRIDILO; R6, R7 Y R8 SON, INDEPENDIENTEMENTE ENTRE SI, H o ALQUILO C1-C4. UNO DE LOS ANTIBIOTICO DE 8-CIANO-QUINOLONA PREFERIDOS ES LA PRADOFLOXACINA, 8-CIANO-1-CICLOPROPIL-7-((1S,6S)-2,8-DIAZABICICLO[4.3.0]NONAN-8-IL)-6-FLUOR-1,4-DIHIDRO-4-OXO-3-QUINOLINCARBOXILICO. LOS ANTIBIOTICOS MENCIONADOS SON UTILESS EN EL TRATAMIENTO SISTEMICO DE ENFERMEDADES BACTERIANAS EN LA CAVIDAD BUCAL PROVOCADAS POR LAS BACTERIAS DEL GRUPO Porphyromonas spp; Prevotella spp; Bacteroides spp; Actinobacillus actinomycetemcomitans; Fusobacterium spp; Peptostreptococcus spp; Eikenella corrodens; Capnocytophaga ochracea; Campylobacter rectus
PE2004000780A 2003-08-13 2004-08-11 Uso de antibioticos de quinolona y 8-ciano-quinolona PE20050341A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10337191A DE10337191A1 (de) 2003-08-13 2003-08-13 Neue Verwendung von Chinolon-Antibiotika

Publications (1)

Publication Number Publication Date
PE20050341A1 true PE20050341A1 (es) 2005-07-07

Family

ID=34201505

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2004000780A PE20050341A1 (es) 2003-08-13 2004-08-11 Uso de antibioticos de quinolona y 8-ciano-quinolona

Country Status (33)

Country Link
US (1) US8658645B2 (es)
EP (1) EP1656143B1 (es)
JP (2) JP5122814B2 (es)
KR (1) KR101209119B1 (es)
CN (1) CN100571702C (es)
AR (2) AR045093A1 (es)
AT (1) ATE528004T1 (es)
AU (2) AU2004266452A1 (es)
BR (1) BRPI0413509A (es)
CA (1) CA2535637C (es)
CY (1) CY1112167T1 (es)
DE (1) DE10337191A1 (es)
DK (1) DK1656143T3 (es)
ES (1) ES2374728T3 (es)
GT (1) GT200400156A (es)
HK (1) HK1098687A1 (es)
HR (1) HRP20120019T1 (es)
IL (1) IL173655A (es)
LU (1) LU91883I2 (es)
MX (1) MXPA06001597A (es)
MY (1) MY162652A (es)
NO (1) NO333116B1 (es)
NZ (1) NZ545261A (es)
PE (1) PE20050341A1 (es)
PL (1) PL1656143T3 (es)
PT (1) PT1656143E (es)
RU (1) RU2367437C2 (es)
SI (1) SI1656143T1 (es)
TW (1) TWI367095B (es)
UA (1) UA85685C2 (es)
UY (1) UY28465A1 (es)
WO (1) WO2005018641A2 (es)
ZA (1) ZA200601167B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10337191A1 (de) * 2003-08-13 2005-03-17 Bayer Healthcare Ag Neue Verwendung von Chinolon-Antibiotika
TW200510425A (en) * 2003-08-13 2005-03-16 Japan Tobacco Inc Nitrogen-containing fused ring compound and use thereof as HIV integrase inhibitor
FR2896416B1 (fr) * 2006-01-24 2010-08-13 Vetoquinol Composition anti-infectieuse comprenant un compose de type pyrido (3,2,1-ij)-benzoxadiazine
DE102006010643A1 (de) * 2006-03-08 2007-09-13 Bayer Healthcare Aktiengesellschaft Arzneimittel enthaltend Fluorchinolone
DE102006049520A1 (de) 2006-10-20 2008-04-24 Bayer Healthcare Ag Verfahren zur Herstellung von Pradofloxacin
DE102007055341A1 (de) * 2007-11-19 2009-05-20 Bayer Animal Health Gmbh Stabilisierung öliger Suspensionen enthaltend hydrophobe Kieselsäuren
WO2010069493A1 (de) * 2008-12-18 2010-06-24 Bayer Animal Health Gmbh Verbesserte wirkstoffkombination enthaltend ein antibiotikum und einen nichtsteroidalen entzündungshemmer (nsaid)
CN102988280B (zh) * 2012-10-08 2014-03-19 新乡医学院 一种加雷沙星滴眼剂
JP6358868B2 (ja) * 2014-06-17 2018-07-18 Ｄｓファーマアニマルヘルス株式会社 オルビフロキサシンを含有する製剤組成物
CN106831795B (zh) * 2017-01-16 2018-12-21 石家庄学院 喹诺酮异土木香内酯衍生物及其制备和应用
US11332444B2 (en) 2018-04-25 2022-05-17 Bayer Animal Health Gmbh Method for the hydrolysis of quinolonecarboxylic esters
JOP20220131A1 (ar) * 2019-11-28 2023-01-30 Bayer Ag مركبات أمينو كينولون تحمل بدائل تستخدم كمثبطات لـ dgkalpha من أجل تنشيط المناعة

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62205060A (ja) * 1986-03-04 1987-09-09 Kyorin Pharmaceut Co Ltd ８位置換キノロンカルボン酸誘導体
DE3702393A1 (de) * 1987-01-28 1988-08-11 Bayer Ag 8-cyano-1-cyclopropyl-1,4-dihydro-4-oxo- 3-chinolincarbonsaeuren, verfahren zu ihrer herstellung und diese enthaltende antibakterielle mittel
DK0882049T3 (da) * 1996-02-23 2003-03-03 Bayer Ag Eventuelt substituerede 8-cyan-1-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-quinolincarboxylsyrer og deres derivater
TW415943B (en) * 1996-06-28 2000-12-21 Bayer Ag 7-(3-vinyl-1,4-piperazin-1-yl)-substituted quinolonecarboxylic acids
DE19633480A1 (de) * 1996-08-20 1998-02-26 Bayer Ag Oral applizierbare Formulierungen von Chinolon- und Naphthyridoncarbonsäuren
DE19652219A1 (de) * 1996-12-16 1998-06-18 Bayer Ag Verwendung von 7-(1-Aminomethyl-2-oxa-7-azabicyclo[3.3.0]oct-7-yl)-chinolon- und naphthyridoncarbonsäure-Derivaten zur Therapie von Helicobacter-pylori-Infektionen und den damit assoziierten gastroduodenalen Erkrankungen
WO1999010351A1 (fr) * 1997-08-22 1999-03-04 Dainippon Pharmaceutical Co., Ltd. Derives d'acide pyridonecarboxylique et intermediaires aux fins de leur preparation
DE19962470A1 (de) 1999-12-22 2001-07-12 Schulz Hans Herrmann Verwendung von Chemotherapeutika
DE10337191A1 (de) * 2003-08-13 2005-03-17 Bayer Healthcare Ag Neue Verwendung von Chinolon-Antibiotika

Also Published As

Publication number Publication date
CA2535637A1 (en) 2005-03-03
JP5122814B2 (ja) 2013-01-16
TW200517110A (en) 2005-06-01
CN100571702C (zh) 2009-12-23
NO20061127L (no) 2006-03-08
RU2006107497A (ru) 2006-08-10
SI1656143T1 (sl) 2012-03-30
AR109644A2 (es) 2019-01-09
EP1656143A2 (de) 2006-05-17
CA2535637C (en) 2011-11-08
KR101209119B1 (ko) 2012-12-07
HK1098687A1 (en) 2007-07-27
AU2011200356A1 (en) 2011-02-17
TWI367095B (en) 2012-07-01
PT1656143E (pt) 2012-01-12
EP1656143B1 (de) 2011-10-12
ATE528004T1 (de) 2011-10-15
JP2007501819A (ja) 2007-02-01
DK1656143T3 (da) 2012-02-06
US8658645B2 (en) 2014-02-25
NZ545261A (en) 2009-11-27
HRP20120019T1 (hr) 2012-02-29
DE10337191A1 (de) 2005-03-17
US20070082911A1 (en) 2007-04-12
ZA200601167B (en) 2007-04-25
GT200400156A (es) 2005-03-23
PL1656143T3 (pl) 2012-03-30
UA85685C2 (ru) 2009-02-25
NO333116B1 (no) 2013-03-04
AR045093A1 (es) 2005-10-12
JP2012211170A (ja) 2012-11-01
AU2011200356B2 (en) 2012-01-12
WO2005018641A3 (de) 2005-10-06
LU91883I2 (fr) 2013-04-12
KR20060061353A (ko) 2006-06-07
MXPA06001597A (es) 2006-05-19
RU2367437C2 (ru) 2009-09-20
WO2005018641A2 (de) 2005-03-03
IL173655A0 (en) 2006-07-05
UY28465A1 (es) 2005-03-31
CY1112167T1 (el) 2015-12-09
CN1867335A (zh) 2006-11-22
BRPI0413509A (pt) 2006-10-10
ES2374728T3 (es) 2012-02-21
AU2004266452A1 (en) 2005-03-03
IL173655A (en) 2013-07-31
MY162652A (en) 2017-06-30

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