PE20030744A1 - Transdiferenciacion de celulas acinosas pancreaticas - Google Patents
Transdiferenciacion de celulas acinosas pancreaticasInfo
- Publication number
- PE20030744A1 PE20030744A1 PE2003000035A PE2003000035A PE20030744A1 PE 20030744 A1 PE20030744 A1 PE 20030744A1 PE 2003000035 A PE2003000035 A PE 2003000035A PE 2003000035 A PE2003000035 A PE 2003000035A PE 20030744 A1 PE20030744 A1 PE 20030744A1
- Authority
- PE
- Peru
- Prior art keywords
- cells
- mammal
- beta cells
- acine
- transdifferentiation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/998—Proteins not provided for elsewhere
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Marine Sciences & Fisheries (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
SE REFIERE A UN METODO PARA INDUCIR LA PRODUCCION DE CELULAS BETA EN UN MAMIFERO QUE COMPRENDE ADMINISTRAR LOCALMENTE MICROESFERAS DE UNA CANTIDAD EFECTIVA DEL PENTADECAPEPTIDO INGAP, O UNA PORCION ACTIVA EL MISMO, A CELULAS ACINOSAS DE UN MAMIFERO LAS QUE SE TRASDIFERENCIAN Y ADQUIEREN LAS CARACTERISTICAS DE CELULAS BETA Y PRODUCEN INSULINA. EL INGAP ES UNA PROTEINA CELULAR ACINOSA Y ACTUA PARA ESTIMULAR LAS CELULAS DUCTALES PARA DIFERENCIARLAS, PARA LLEGAR A SER CELULAS BETA LAS QUE PUEDEN SER USADAS INTER ALIA PARA TRASPLANTE Y MEJORAR EL ESTADO GLICEMICO DEL MAMIFERO
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34689002P | 2002-01-11 | 2002-01-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20030744A1 true PE20030744A1 (es) | 2003-10-24 |
Family
ID=23361448
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2003000035A PE20030744A1 (es) | 2002-01-11 | 2003-01-09 | Transdiferenciacion de celulas acinosas pancreaticas |
Country Status (20)
Country | Link |
---|---|
US (1) | US7662768B2 (es) |
EP (1) | EP1463801B1 (es) |
JP (1) | JP2005514426A (es) |
KR (1) | KR20040072680A (es) |
CN (1) | CN1610693A (es) |
AR (1) | AR038281A1 (es) |
AT (1) | ATE404661T1 (es) |
AU (1) | AU2003201553A1 (es) |
BR (1) | BR0306656A (es) |
CA (1) | CA2469052A1 (es) |
DE (1) | DE60322831D1 (es) |
IL (1) | IL162749A0 (es) |
MA (1) | MA27413A1 (es) |
MX (1) | MXPA04006385A (es) |
NO (1) | NO20042205L (es) |
PE (1) | PE20030744A1 (es) |
PL (1) | PL371260A1 (es) |
RU (1) | RU2004119417A (es) |
TW (1) | TW200302228A (es) |
WO (1) | WO2003057862A2 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2003275853A1 (en) * | 2002-10-24 | 2004-05-13 | Mcgill University | Use of ingap for reversing diabetes |
US20160039877A1 (en) | 2013-03-15 | 2016-02-11 | Shenzhen Hightide Biopharmaceutical, Ltd. | Compositions and methods of using islet neogenesis peptides and analogs thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0815129B1 (en) * | 1995-02-22 | 2011-01-05 | Eastern Virginia Medical School of the Medical College of Hampton Roads | Ingap protein involved in pancreatic islet neogenesis |
US5834590A (en) * | 1995-02-22 | 1998-11-10 | Eastern Virginia Medical School Of The Medical College Of Hampton Roads | Ingap protein involved in pancreatic islet neogenesis |
CA2463914A1 (en) * | 2001-10-18 | 2003-04-24 | Ixion Biotechnology, Inc. | Conversion of liver stem and progenitor cells to pancreatic functional cells |
-
2003
- 2003-01-08 US US10/338,028 patent/US7662768B2/en not_active Expired - Fee Related
- 2003-01-09 AR ARP030100050A patent/AR038281A1/es unknown
- 2003-01-09 PE PE2003000035A patent/PE20030744A1/es not_active Application Discontinuation
- 2003-01-10 KR KR10-2004-7010139A patent/KR20040072680A/ko not_active Application Discontinuation
- 2003-01-10 AT AT03700250T patent/ATE404661T1/de not_active IP Right Cessation
- 2003-01-10 DE DE60322831T patent/DE60322831D1/de not_active Expired - Lifetime
- 2003-01-10 TW TW092100552A patent/TW200302228A/zh unknown
- 2003-01-10 AU AU2003201553A patent/AU2003201553A1/en not_active Abandoned
- 2003-01-10 JP JP2003558163A patent/JP2005514426A/ja active Pending
- 2003-01-10 CN CNA038018616A patent/CN1610693A/zh active Pending
- 2003-01-10 PL PL03371260A patent/PL371260A1/xx unknown
- 2003-01-10 MX MXPA04006385A patent/MXPA04006385A/es not_active Application Discontinuation
- 2003-01-10 BR BR0306656-8A patent/BR0306656A/pt not_active Application Discontinuation
- 2003-01-10 IL IL16274903A patent/IL162749A0/xx unknown
- 2003-01-10 RU RU2004119417/14A patent/RU2004119417A/ru not_active Application Discontinuation
- 2003-01-10 WO PCT/CA2003/000013 patent/WO2003057862A2/en active IP Right Grant
- 2003-01-10 EP EP03700250A patent/EP1463801B1/en not_active Expired - Lifetime
- 2003-01-10 CA CA002469052A patent/CA2469052A1/en not_active Abandoned
-
2004
- 2004-05-28 NO NO20042205A patent/NO20042205L/no not_active Application Discontinuation
- 2004-06-28 MA MA27750A patent/MA27413A1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
BR0306656A (pt) | 2004-10-05 |
KR20040072680A (ko) | 2004-08-18 |
CN1610693A (zh) | 2005-04-27 |
US20030203850A1 (en) | 2003-10-30 |
AU2003201553A1 (en) | 2003-07-24 |
ATE404661T1 (de) | 2008-08-15 |
AR038281A1 (es) | 2005-01-12 |
NO20042205L (no) | 2004-09-13 |
DE60322831D1 (de) | 2008-09-25 |
EP1463801A2 (en) | 2004-10-06 |
TW200302228A (en) | 2003-08-01 |
MA27413A1 (fr) | 2005-07-01 |
PL371260A1 (en) | 2005-06-13 |
US7662768B2 (en) | 2010-02-16 |
JP2005514426A (ja) | 2005-05-19 |
WO2003057862A2 (en) | 2003-07-17 |
RU2004119417A (ru) | 2005-02-27 |
IL162749A0 (en) | 2005-11-20 |
CA2469052A1 (en) | 2003-07-17 |
EP1463801B1 (en) | 2008-08-13 |
MXPA04006385A (es) | 2004-10-04 |
WO2003057862A3 (en) | 2003-10-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |