PE20020260A1 - Proceso para preparar 2-(4-piridil) amino-6-dialquiloxifenil-pirido [2,3-d]pirimidin-7-onas - Google Patents
Proceso para preparar 2-(4-piridil) amino-6-dialquiloxifenil-pirido [2,3-d]pirimidin-7-onasInfo
- Publication number
- PE20020260A1 PE20020260A1 PE2001000775A PE2001000775A PE20020260A1 PE 20020260 A1 PE20020260 A1 PE 20020260A1 PE 2001000775 A PE2001000775 A PE 2001000775A PE 2001000775 A PE2001000775 A PE 2001000775A PE 20020260 A1 PE20020260 A1 PE 20020260A1
- Authority
- PE
- Peru
- Prior art keywords
- pyrid
- phenyl
- formula
- pyrimidine
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
SE REFIERE A UN PROCESO PARA PREPARAR 2-(PIRIDIN-4-ILAMINO)-PIRIDO[2,3-d]PIRIMIDINA DE FORMULA II; QUE COMPRENDE REACCIONAR 4-AMINOPIRIDINA DE FORMULA a; CON UN HIDRURO O AMIDA DE METAL ALCALINO Y 2-ALQUILSULFANILPIRIDO[2,3-d]PIRIMIDINA DE FORMULA I; R' Y R" SON H, ALQUILO C1-C6, HALOGENO, FENILO; R2 ES H, CH2)nPh, CICLOALQUILO, ALQUILO C1-C6 OPCIONALMENTE SUSTITUIDOS CON NR5R6; Ph ES FENILO; n ES 0-3; Ar ES FENILO HETEROAROMATICO; R5 Y R6 SON H, ALQUILO C1-C6, ALQUENILO C2-C6, (CH2)nPh O JUNTOS FORMAN UN ANILLO DE 3-7 MIEMBROS. LOS COMPUESTOS PIRIDO[2,3-d]PIRIMIDINAS INHIBEN LA PROLIFERACION CELULAR MEDIADA POR TIROSINQUINASA Y PUEDEN SER UTILES PARA TRATAR CANCER
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22286600P | 2000-08-04 | 2000-08-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20020260A1 true PE20020260A1 (es) | 2002-04-19 |
Family
ID=22834051
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2001000775A PE20020260A1 (es) | 2000-08-04 | 2001-08-03 | Proceso para preparar 2-(4-piridil) amino-6-dialquiloxifenil-pirido [2,3-d]pirimidin-7-onas |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6900316B2 (es) |
| EP (1) | EP1417207B1 (es) |
| JP (1) | JP2005507392A (es) |
| AP (1) | AP1334A (es) |
| AR (1) | AR031121A1 (es) |
| AT (1) | ATE303385T1 (es) |
| AU (1) | AU2001298008A1 (es) |
| BR (1) | BR0113037A (es) |
| CA (1) | CA2424057A1 (es) |
| DE (1) | DE60113161T2 (es) |
| DK (1) | DK1417207T3 (es) |
| DO (1) | DOP2001000226A (es) |
| ES (1) | ES2248233T3 (es) |
| GT (1) | GT200100157A (es) |
| HN (1) | HN2001000172A (es) |
| MX (1) | MXPA03000865A (es) |
| PA (1) | PA8524001A1 (es) |
| PE (1) | PE20020260A1 (es) |
| PT (1) | PT1417207E (es) |
| SV (1) | SV2002000573A (es) |
| TN (1) | TNSN01117A1 (es) |
| UY (1) | UY26866A1 (es) |
| WO (1) | WO2003027110A2 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6960662B2 (en) * | 2000-08-04 | 2005-11-01 | Warner-Lambert Company | Process for preparing 2-(4-pyridyl)amino-6-dialkyloxyphenyl-pyrido[2,3-d]pyrimidin-7-ones |
| MXPA02011263A (es) * | 2000-08-04 | 2003-03-10 | Warner Lambert Co | 2-(4-piridil)amino-6-dialcoxifenil- pirido(2,3-d) pirimidin-7-onas. |
| US6518276B2 (en) * | 2000-08-31 | 2003-02-11 | Syntex (U.S.A.) Llc | 7-oxo-pyridopyrimidines (II) |
| US7196090B2 (en) * | 2002-07-25 | 2007-03-27 | Warner-Lambert Company | Kinase inhibitors |
| BRPI0507852A (pt) * | 2004-02-18 | 2007-07-10 | Warner Lambert Co | 2-(piridin-3-ilamino)-pirido[2,3-d]pirimidin-7-onas |
| DE102004054215A1 (de) | 2004-11-10 | 2006-05-11 | Merck Patent Gmbh | Pyridopyrimidinonderivate |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL117923A (en) | 1995-05-03 | 2000-06-01 | Warner Lambert Co | Anti-cancer pharmaceutical compositions containing polysubstituted pyrido¬2,3-d¾pyrimidine derivatives and certain such novel compounds |
| US5620981A (en) * | 1995-05-03 | 1997-04-15 | Warner-Lambert Company | Pyrido [2,3-D]pyrimidines for inhibiting protein tyrosine kinase mediated cellular proliferation |
| US5945422A (en) * | 1997-02-05 | 1999-08-31 | Warner-Lambert Company | N-oxides of amino containing pyrido 2,3-D! pyrimidines |
| CA2394650A1 (en) | 1999-12-17 | 2001-06-21 | Chi B. Vu | Novel heterocycles |
| US6960662B2 (en) * | 2000-08-04 | 2005-11-01 | Warner-Lambert Company | Process for preparing 2-(4-pyridyl)amino-6-dialkyloxyphenyl-pyrido[2,3-d]pyrimidin-7-ones |
| MXPA02011263A (es) * | 2000-08-04 | 2003-03-10 | Warner Lambert Co | 2-(4-piridil)amino-6-dialcoxifenil- pirido(2,3-d) pirimidin-7-onas. |
| GEP20063909B (en) * | 2002-01-22 | 2006-08-25 | Warner Lambert Co | 2-(PYRIDIN-2-YLAMINO)-PYRIDO[2,3d] PYRIMIDIN-7-ONES |
-
2001
- 2001-07-12 AU AU2001298008A patent/AU2001298008A1/en not_active Abandoned
- 2001-07-12 EP EP01274395A patent/EP1417207B1/en not_active Expired - Lifetime
- 2001-07-12 CA CA002424057A patent/CA2424057A1/en not_active Abandoned
- 2001-07-12 AT AT01274395T patent/ATE303385T1/de not_active IP Right Cessation
- 2001-07-12 US US10/343,803 patent/US6900316B2/en not_active Expired - Fee Related
- 2001-07-12 MX MXPA03000865A patent/MXPA03000865A/es active IP Right Grant
- 2001-07-12 ES ES01274395T patent/ES2248233T3/es not_active Expired - Lifetime
- 2001-07-12 DK DK01274395T patent/DK1417207T3/da active
- 2001-07-12 DE DE60113161T patent/DE60113161T2/de not_active Expired - Fee Related
- 2001-07-12 PT PT01274395T patent/PT1417207E/pt unknown
- 2001-07-12 WO PCT/US2001/051422 patent/WO2003027110A2/en active IP Right Grant
- 2001-07-12 JP JP2003530698A patent/JP2005507392A/ja active Pending
- 2001-07-12 BR BR0113037-4A patent/BR0113037A/pt not_active IP Right Cessation
- 2001-07-20 AP APAP/P/2001/002231A patent/AP1334A/en active
- 2001-07-27 SV SV2001000573A patent/SV2002000573A/es not_active Application Discontinuation
- 2001-08-01 TN TNTNSN01117A patent/TNSN01117A1/en unknown
- 2001-08-03 PA PA20018524001A patent/PA8524001A1/es unknown
- 2001-08-03 PE PE2001000775A patent/PE20020260A1/es not_active Application Discontinuation
- 2001-08-03 AR ARP010103715A patent/AR031121A1/es not_active Application Discontinuation
- 2001-08-03 DO DO2001000226A patent/DOP2001000226A/es unknown
- 2001-08-03 UY UY26866A patent/UY26866A1/es not_active Application Discontinuation
- 2001-08-03 HN HN2001000172A patent/HN2001000172A/es unknown
- 2001-08-03 GT GT200100157A patent/GT200100157A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AP2001002231A0 (en) | 2001-09-30 |
| PA8524001A1 (es) | 2002-07-30 |
| PT1417207E (pt) | 2005-11-30 |
| UY26866A1 (es) | 2001-09-28 |
| US6900316B2 (en) | 2005-05-31 |
| US20030176700A1 (en) | 2003-09-18 |
| JP2005507392A (ja) | 2005-03-17 |
| SV2002000573A (es) | 2002-01-16 |
| MXPA03000865A (es) | 2003-06-18 |
| WO2003027110A2 (en) | 2003-04-03 |
| WO2003027110A3 (en) | 2004-02-26 |
| EP1417207B1 (en) | 2005-08-31 |
| TNSN01117A1 (en) | 2005-11-10 |
| BR0113037A (pt) | 2004-01-20 |
| DOP2001000226A (es) | 2002-06-15 |
| GT200100157A (es) | 2002-07-18 |
| HN2001000172A (es) | 2005-03-04 |
| DK1417207T3 (da) | 2005-12-27 |
| CA2424057A1 (en) | 2003-04-03 |
| AR031121A1 (es) | 2003-09-10 |
| ES2248233T3 (es) | 2006-03-16 |
| AU2001298008A1 (en) | 2003-04-07 |
| DE60113161T2 (de) | 2006-06-14 |
| AP1334A (en) | 2004-11-29 |
| DE60113161D1 (de) | 2005-10-06 |
| EP1417207A2 (en) | 2004-05-12 |
| ATE303385T1 (de) | 2005-09-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PE20020305A1 (es) | 2-(4-PIRIDIL) AMINO-6-DIALCOXIFENIL-PIRIDO [2,3-d] PIRIMIDIN-7-ONAS COMO INHIBIDORES DE LA TIROSINA QUINASA | |
| AR082864A2 (es) | Preparacion de compuestos de aminopirimidina | |
| CY1119099T1 (el) | Διαδικασια για την παρασκευη αναστολεων του μεταβολισμου των νουκλεοζιτων | |
| BR9611618A (pt) | Composto processo para sua preparação composição farmacêutica e utilização de um compostos | |
| TW359670B (en) | Process for producing quinazolin-4-one derivatives | |
| DK0847392T3 (da) | Fremgangsmåde til fremstilling af quinazolinderivater | |
| PE20020219A1 (es) | Derivados de 6-fenilpirrolpirimidindiona como inhibidores de fosfodiesterasa 5 | |
| SE8301412L (sv) | Substituerade 1h-pyrazolo(1,5)pyrimidiner och forfarande for deras framstellning | |
| KR840006633A (ko) | 벤족사졸리논 유도체의 제조방법 | |
| AU3415599A (en) | Benzoheterocyclic distamycin derivatives, process for preparing them, and their use as antitumor agents | |
| PE20020260A1 (es) | Proceso para preparar 2-(4-piridil) amino-6-dialquiloxifenil-pirido [2,3-d]pirimidin-7-onas | |
| TW352383B (en) | Hydroximic acid derivatives, processes for their preparation, and compositions comprising them | |
| ATE217869T1 (de) | Verfahren zur herstellung von fluoralkenylthio heterozyclische derivate | |
| RS51126B (sr) | Postupak za pripremanje mezilata piperazin derivata | |
| DK176890A (da) | Analogifremgangsmaade til fremstilling af dialkylaminoethenyl-2(1h)pyridinoner | |
| NZ333229A (es) | ||
| UA72934C2 (uk) | Феніл- і піридилтетрагідропіридини, що інгібують фактор некрозу пухлин, спосіб їх одержання та фармацевтична композиція | |
| IS2419B (is) | Glýsín-setin þíeno[2,3-d]pýrimidín með sameinaða LH og FSH gerandefnisvirkni | |
| NO911224D0 (no) | Smoereoljeadditiver, deres fremstilling og anvendelse. | |
| HU0001127D0 (en) | Process for producing n-[5-(diphenyl-phosphinoyl-methyl)-4-(4-fluorphenyl-6-isopropyl-pyrimidin-2-yl]-n-methylmethan sulfonamid | |
| MXPA01008189A (es) | Proceso para la preparacion de compuestos 6-)perfluoroalquil) uracilo a partir de compuestos de urea. | |
| ECSP972062A (es) | Nuevos derivados de 2 -(3h) -oxazolona | |
| ECSP920821A (es) | Composiciones heterocyclicas | |
| TR200402333T4 (tr) | Artropodisidal karboksanilidler |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |