PE20010459A1 - Uso de un compuesto calciolitico con un agente antiresorcion - Google Patents
Uso de un compuesto calciolitico con un agente antiresorcionInfo
- Publication number
- PE20010459A1 PE20010459A1 PE2000000756A PE0007562000A PE20010459A1 PE 20010459 A1 PE20010459 A1 PE 20010459A1 PE 2000000756 A PE2000000756 A PE 2000000756A PE 0007562000 A PE0007562000 A PE 0007562000A PE 20010459 A1 PE20010459 A1 PE 20010459A1
- Authority
- PE
- Peru
- Prior art keywords
- phenoxy
- propyl
- hydroxy
- dimethyl
- amine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
SE REFIERE AL USO DE COMPUESTOS INHIBIDORES DE LA ACTIVIDAD DE LOS RECEPTORES DE CALCIO TAL COMO HIDROCLORURO DE N-[(2R-HIDROXI-3-[(3-CLORO-2-CIANO)FENOXI-PROPIL]-1,1-DIMETIL-2-(2-NAFTIL)-ETIL-AMINA, HIDROCLORURO DE N-[(2R-HIDROXI-3-[(3-CLORO-2-CIANO)FENOXI-PROPIL]-1,1-DIMETIL-2-(4-METOXIFENIL)ETIL-AMINA, HIDROCLORURO DE N-[(2R-HIDROXI-3-[(2,3-DICLORO)FENOXI-PROPIL]-1,1-DIMETIL-2-(4-METOXIFENIL)ETIL-AMINA, ENTRE OTROS; CON UN AGENTE DE ANTI-RESORCION TAL COMO ESTROGENOS, 1,25(OH)2-VITAMINA D3, CALCITONINA, MODULADORES SELECTIVOS DE LOS RECEPTORES DE ESTROGENOS, ANTAGONISTAS DEL RECEPTOR DE VITRONECTINA, INHIBIDORES DE LA V-H+-ADENOSINA-FOSFATASA, ANTAGONISTAS src DE SH2, BISFOSFONATOS Y LOS INHIBIDORES DE LA CATEPSINA K. EL AGENTE CALCIOLITICO PRODUCE UN AUMENTO EN LOS NIVELES DE LA HORMONA PARATIROIDEA EN SUERO DE TRES VECES O MAS. LA ADMINISTRACION CONJUNTA DE UN AGENTE CALCIOLITICO CON UN AGENTRE ANTI-RESORCION PUEDE SER UTIL PARA EL TRATAMIENTO DE UN TRASTORNO OSEO MINERAL TAL COMO ENFERMEDAD PERIODONTAL, CONSOLIDACION DE FRACTURAS, OSTEOARTRITIS, ARTRITIS REUMATOIDE, OSTEOPOROSIS, HIPERCALCEMIA HUMORAL MALIGNA, ENFERMEDAD METASTASICA DE LOS HUESOS, PROTESIS ARTICULARES
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14677899P | 1999-07-31 | 1999-07-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20010459A1 true PE20010459A1 (es) | 2001-06-11 |
Family
ID=22518969
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2000000756A PE20010459A1 (es) | 1999-07-31 | 2000-07-31 | Uso de un compuesto calciolitico con un agente antiresorcion |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP1200076A4 (es) |
JP (1) | JP2003505502A (es) |
KR (1) | KR20020016928A (es) |
CN (1) | CN1367687A (es) |
AU (1) | AU764716B2 (es) |
BR (1) | BR0012921A (es) |
CA (1) | CA2380081A1 (es) |
CO (1) | CO5180628A1 (es) |
CZ (1) | CZ2002360A3 (es) |
EC (1) | ECSP003590A (es) |
HK (1) | HK1046238A1 (es) |
HU (1) | HUP0202167A3 (es) |
IL (1) | IL147875A0 (es) |
MX (1) | MXPA02001204A (es) |
NO (1) | NO20020466L (es) |
PE (1) | PE20010459A1 (es) |
PL (1) | PL353318A1 (es) |
TR (1) | TR200200278T2 (es) |
UY (1) | UY26265A1 (es) |
WO (1) | WO2001008673A1 (es) |
ZA (1) | ZA200200784B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY159417A (en) * | 2000-01-24 | 2017-01-13 | Smithkline Beecham Corp | Calcilytic compounds |
US20030018203A1 (en) | 2002-07-17 | 2003-01-23 | Largo Maria Amparo | Calcilytic compounds |
US6756480B2 (en) | 2000-04-27 | 2004-06-29 | Amgen Inc. | Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein |
TWI316511B (en) | 2002-11-26 | 2009-11-01 | Smithkline Beecham Corp | Calcilytic compounds |
US7205322B2 (en) | 2003-02-12 | 2007-04-17 | Bristol-Myers Squibb Company | Thiazolidine compounds as calcium sensing receptor modulators |
US7265145B2 (en) | 2003-05-28 | 2007-09-04 | Bristol-Myers Squibb Company | Substituted piperidines and pyrrolidines as calcium sensing receptor modulators and method |
TW200845956A (en) * | 2006-12-18 | 2008-12-01 | Smithkline Beecham Corp | Calcilytic compounds |
WO2013098588A1 (en) * | 2011-12-27 | 2013-07-04 | Ubaldo Armato | Use of calcilytic drugs as a pharmacological approach to the treatment and prevention of alzheimer's disease, alzheimer's disease-related disorders, and down's syndrome neuropathies |
GB201217330D0 (en) | 2012-09-28 | 2012-11-14 | Univ Cardiff | Therapeutic for treating inflammatory lung disorders |
CN108420814A (zh) * | 2017-02-15 | 2018-08-21 | 四川大学 | 一种nps-2143用于抗菌的新用途 |
CN116173187B (zh) * | 2023-03-14 | 2024-05-10 | 哈尔滨医科大学 | 降钙素在制备防治支架内再狭窄药物中的应用、药物涂层支架及制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU726659B2 (en) * | 1996-04-09 | 2000-11-16 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
AR018177A1 (es) * | 1998-04-08 | 2001-10-31 | Smithkline Beecham Corp | Compuestos calciliticos, una composicion farmaceutica que los comprende y el uso de los mismos para la manufactura de un medicamento. |
AR014975A1 (es) * | 1998-04-08 | 2001-04-11 | Nps Pharma Inc | Compuestos calciliticos, una composicion farmaceutica que los comprende, y el uso de los mismos para la fabricacion de un medicamento |
-
2000
- 2000-07-28 EC EC2000003590A patent/ECSP003590A/es unknown
- 2000-07-28 CO CO00056902A patent/CO5180628A1/es not_active Application Discontinuation
- 2000-07-31 MX MXPA02001204A patent/MXPA02001204A/es active IP Right Grant
- 2000-07-31 PL PL00353318A patent/PL353318A1/xx unknown
- 2000-07-31 PE PE2000000756A patent/PE20010459A1/es not_active Application Discontinuation
- 2000-07-31 UY UY26265A patent/UY26265A1/es not_active Application Discontinuation
- 2000-07-31 BR BR0012921-6A patent/BR0012921A/pt not_active Application Discontinuation
- 2000-07-31 CZ CZ2002360A patent/CZ2002360A3/cs unknown
- 2000-07-31 KR KR1020027001298A patent/KR20020016928A/ko not_active Application Discontinuation
- 2000-07-31 CN CN00811177A patent/CN1367687A/zh active Pending
- 2000-07-31 AU AU65041/00A patent/AU764716B2/en not_active Ceased
- 2000-07-31 IL IL14787500A patent/IL147875A0/xx unknown
- 2000-07-31 WO PCT/US2000/020834 patent/WO2001008673A1/en active Application Filing
- 2000-07-31 TR TR2002/00278T patent/TR200200278T2/xx unknown
- 2000-07-31 CA CA002380081A patent/CA2380081A1/en not_active Abandoned
- 2000-07-31 EP EP00952319A patent/EP1200076A4/en not_active Withdrawn
- 2000-07-31 HU HU0202167A patent/HUP0202167A3/hu unknown
- 2000-07-31 JP JP2001513403A patent/JP2003505502A/ja not_active Withdrawn
-
2002
- 2002-01-29 NO NO20020466A patent/NO20020466L/no not_active Application Discontinuation
- 2002-01-29 ZA ZA200201784A patent/ZA200200784B/xx unknown
- 2002-10-15 HK HK02107473.9A patent/HK1046238A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
AU764716B2 (en) | 2003-08-28 |
ECSP003590A (es) | 2002-02-25 |
PL353318A1 (en) | 2003-11-17 |
NO20020466L (no) | 2002-03-20 |
CO5180628A1 (es) | 2002-07-30 |
CA2380081A1 (en) | 2001-02-08 |
JP2003505502A (ja) | 2003-02-12 |
BR0012921A (pt) | 2002-06-18 |
WO2001008673A1 (en) | 2001-02-08 |
CZ2002360A3 (cs) | 2002-10-16 |
MXPA02001204A (es) | 2004-05-21 |
IL147875A0 (en) | 2002-08-14 |
EP1200076A4 (en) | 2005-02-09 |
ZA200200784B (en) | 2003-01-29 |
KR20020016928A (ko) | 2002-03-06 |
CN1367687A (zh) | 2002-09-04 |
HK1046238A1 (zh) | 2003-01-03 |
TR200200278T2 (tr) | 2002-06-21 |
NO20020466D0 (no) | 2002-01-29 |
UY26265A1 (es) | 2001-03-16 |
HUP0202167A3 (en) | 2006-07-28 |
AU6504100A (en) | 2001-02-19 |
EP1200076A1 (en) | 2002-05-02 |
HUP0202167A2 (en) | 2002-10-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Refusal |