PE20000423A1 - Derivado del acido 2-metilpropionico y composicion farmaceutica que lo contiene - Google Patents
Derivado del acido 2-metilpropionico y composicion farmaceutica que lo contieneInfo
- Publication number
- PE20000423A1 PE20000423A1 PE1999000296A PE00029699A PE20000423A1 PE 20000423 A1 PE20000423 A1 PE 20000423A1 PE 1999000296 A PE1999000296 A PE 1999000296A PE 00029699 A PE00029699 A PE 00029699A PE 20000423 A1 PE20000423 A1 PE 20000423A1
- Authority
- PE
- Peru
- Prior art keywords
- cafiles
- methylpropionic acid
- pharmaceutical composition
- composition containing
- acid derivative
- Prior art date
Links
- KQNPFQTWMSNSAP-UHFFFAOYSA-N isobutyric acid Chemical class CC(C)C(O)=O KQNPFQTWMSNSAP-UHFFFAOYSA-N 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 206010052402 Gastrointestinal hypermotility Diseases 0.000 abstract 1
- 101000740162 Homo sapiens Sodium- and chloride-dependent transporter XTRP3 Proteins 0.000 abstract 1
- -1 IMINO Chemical class 0.000 abstract 1
- 206010021639 Incontinence Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 102100037189 Sodium- and chloride-dependent transporter XTRP3 Human genes 0.000 abstract 1
- 206010046543 Urinary incontinence Diseases 0.000 abstract 1
- 108040005346 beta3-adrenergic receptor activity proteins Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 201000001421 hyperglycemia Diseases 0.000 abstract 1
- 208000018936 intestinal hypermotility Diseases 0.000 abstract 1
- 230000037036 intestinal hypermotility Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 230000002485 urinary effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/60—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/18—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to carbon atoms of six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE REFIERE A UN DERIVADO DEL ACIDO 2-METILPROPIONICO DE FORMULA I, DONDE R1 ES H, ALQUILO, ARALQUILO; R2 ES H, ALQUILO, HALOGENO; A ES O, IMINO. TAMBIEN SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION. EL COMPUESTO I TIENE EFECTOS ESTIMULANTES DE ß3-ADRENOCEPTORES Y PUEDE SER UTIL PARA LA PREVENCION O TRATAMIENTO DE LA OBESIDAD, HIPERGLICEMIA, ENFERMEDADES CAUSADAS POR LA HIPERMOTILIDAD INTESTINAL, POLAQUIURIA, INCONTINENCIA URINARIA, DEPRESION, ENFERMEDDES CAUSADAS POR CALCULOS BILIARES, HIPERMOTILIDAD DEL TRACTO BILIAR
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14202898 | 1998-04-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20000423A1 true PE20000423A1 (es) | 2000-05-22 |
Family
ID=15305697
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE1999000296A PE20000423A1 (es) | 1998-04-14 | 1999-04-12 | Derivado del acido 2-metilpropionico y composicion farmaceutica que lo contiene |
Country Status (19)
Country | Link |
---|---|
US (2) | US6696489B1 (es) |
EP (1) | EP1072583B1 (es) |
JP (1) | JP4212771B2 (es) |
KR (1) | KR100576131B1 (es) |
AR (1) | AR015761A1 (es) |
AT (1) | ATE275126T1 (es) |
AU (1) | AU768217C (es) |
CA (1) | CA2328348C (es) |
CO (1) | CO5021214A1 (es) |
DE (1) | DE69919860T2 (es) |
ES (1) | ES2228028T3 (es) |
IL (1) | IL138994A (es) |
MY (1) | MY122400A (es) |
NO (1) | NO20005164L (es) |
NZ (1) | NZ507486A (es) |
PE (1) | PE20000423A1 (es) |
TW (1) | TW581754B (es) |
WO (1) | WO1999052856A1 (es) |
ZA (1) | ZA200005589B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE309978T1 (de) * | 1999-01-21 | 2005-12-15 | Kissei Pharmaceutical | Kristall-polymorphismus von derivaten der aminoethyl-phenoxyessigsäure |
CA2503570C (en) | 2002-11-07 | 2011-04-19 | Yamanouchi Pharmaceutical Co., Ltd. | Remedy for overactive bladder comprising acetic acid anilide derivative as the active ingredient |
EP1424079A1 (en) * | 2002-11-27 | 2004-06-02 | Boehringer Ingelheim International GmbH | Combination of a beta-3-receptor agonist and of a reuptake inhibitor of serotonin and/or norepinephrine |
BRPI0407386A (pt) * | 2003-02-14 | 2006-02-07 | Kissei Pharmaceutical | Derivados de álcool de amino, composições farmacêuticas contendo os mesmos e uso destes |
ITMI20061581A1 (it) | 2006-08-04 | 2008-02-05 | Univ Bari | Ligandi del recettore beta-3 adrenergico e loro uso in terapia |
TWI478712B (zh) | 2008-09-30 | 2015-04-01 | Astellas Pharma Inc | 釋控性醫藥組成物 |
US20120070465A1 (en) | 2010-03-29 | 2012-03-22 | Astellas Pharma Inc. | Pharmaceutical composition for modified release |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4146638A (en) * | 1976-02-17 | 1979-03-27 | Boehringer Ingelheim Gmbh | N-(3-phenoxy-2-hydroxy-propyl)-n-(2-phenyl-2-hydroxy-ethyl)-amines |
EP0023385B1 (en) * | 1979-06-16 | 1982-12-15 | Beecham Group Plc | Ethanamine derivatives, their preparation and use in pharmaceutical compositions |
FR2750668B1 (fr) | 1996-07-03 | 1998-11-20 | Savard Franck | Dispositif de tension et de guidage d'une chaine pour un changement de vitesses de velo |
AU4320297A (en) * | 1996-09-26 | 1998-04-17 | Kissei Pharmaceutical Co. Ltd. | 2-amino-1-(4-hydroxy-2-methylphenyl)propanol derivatives |
ID24062A (id) * | 1997-07-25 | 2000-07-06 | Kissei Pharmaceutical | Turunan-turunan asam aminoetilfenoksiasetat dan obat untuk mengurangi nyeri dan membantu penyingkiran dalam litiasis saluran air kencing |
JP4156799B2 (ja) * | 1997-12-18 | 2008-09-24 | キッセイ薬品工業株式会社 | フェニルアミノアルキルカルボン酸誘導体およびそれを含有する医薬組成物 |
-
1999
- 1999-04-07 AU AU31661/99A patent/AU768217C/en not_active Ceased
- 1999-04-07 US US09/673,308 patent/US6696489B1/en not_active Expired - Fee Related
- 1999-04-07 DE DE69919860T patent/DE69919860T2/de not_active Expired - Lifetime
- 1999-04-07 IL IL13899499A patent/IL138994A/en not_active IP Right Cessation
- 1999-04-07 ES ES99913563T patent/ES2228028T3/es not_active Expired - Lifetime
- 1999-04-07 JP JP2000543419A patent/JP4212771B2/ja not_active Expired - Fee Related
- 1999-04-07 WO PCT/JP1999/001836 patent/WO1999052856A1/ja active IP Right Grant
- 1999-04-07 NZ NZ507486A patent/NZ507486A/xx unknown
- 1999-04-07 KR KR1020007011387A patent/KR100576131B1/ko not_active IP Right Cessation
- 1999-04-07 CA CA002328348A patent/CA2328348C/en not_active Expired - Fee Related
- 1999-04-07 EP EP99913563A patent/EP1072583B1/en not_active Expired - Lifetime
- 1999-04-07 AT AT99913563T patent/ATE275126T1/de not_active IP Right Cessation
- 1999-04-08 TW TW088105577A patent/TW581754B/zh not_active IP Right Cessation
- 1999-04-09 MY MYPI99001392A patent/MY122400A/en unknown
- 1999-04-12 PE PE1999000296A patent/PE20000423A1/es not_active Application Discontinuation
- 1999-04-13 CO CO99021754A patent/CO5021214A1/es unknown
- 1999-04-13 AR ARP990101685A patent/AR015761A1/es unknown
-
2000
- 2000-10-11 ZA ZA200005589A patent/ZA200005589B/en unknown
- 2000-10-13 NO NO20005164A patent/NO20005164L/no unknown
-
2003
- 2003-02-05 US US10/358,214 patent/US6790865B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2328348A1 (en) | 1999-10-21 |
MY122400A (en) | 2006-04-29 |
EP1072583A1 (en) | 2001-01-31 |
EP1072583B1 (en) | 2004-09-01 |
CA2328348C (en) | 2009-03-03 |
US20030166719A1 (en) | 2003-09-04 |
AR015761A1 (es) | 2001-05-16 |
IL138994A0 (en) | 2001-11-25 |
JP4212771B2 (ja) | 2009-01-21 |
AU768217B2 (en) | 2003-12-04 |
AU3166199A (en) | 1999-11-01 |
KR20010042683A (ko) | 2001-05-25 |
US6696489B1 (en) | 2004-02-24 |
IL138994A (en) | 2004-02-19 |
DE69919860T2 (de) | 2005-08-25 |
CO5021214A1 (es) | 2001-03-27 |
DE69919860D1 (de) | 2004-10-07 |
TW581754B (en) | 2004-04-01 |
US6790865B2 (en) | 2004-09-14 |
WO1999052856A1 (fr) | 1999-10-21 |
NO20005164L (no) | 2000-12-12 |
NO20005164D0 (no) | 2000-10-13 |
EP1072583A4 (en) | 2001-12-05 |
KR100576131B1 (ko) | 2006-05-03 |
ATE275126T1 (de) | 2004-09-15 |
AU768217C (en) | 2005-04-21 |
ZA200005589B (en) | 2002-01-11 |
ES2228028T3 (es) | 2005-04-01 |
NZ507486A (en) | 2003-03-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant, registration | ||
FD | Application declared void or lapsed |