PA8798801A1 - Dioxalano timina fosforamidatos como agentes anti-vih. - Google Patents

Dioxalano timina fosforamidatos como agentes anti-vih.

Info

Publication number
PA8798801A1
PA8798801A1 PA20088798801A PA8798801A PA8798801A1 PA 8798801 A1 PA8798801 A1 PA 8798801A1 PA 20088798801 A PA20088798801 A PA 20088798801A PA 8798801 A PA8798801 A PA 8798801A PA 8798801 A1 PA8798801 A1 PA 8798801A1
Authority
PA
Panama
Prior art keywords
dioxalano
timina
phosphoramidates
hiv agents
hiv
Prior art date
Application number
PA20088798801A
Other languages
English (en)
Inventor
Michael J Sofia
Peiyuan Wang
Suguna H Rachakonda
Jinfa Du
Original Assignee
Pharmasset Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40194640&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PA8798801(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmasset Inc filed Critical Pharmasset Inc
Publication of PA8798801A1 publication Critical patent/PA8798801A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE DESCRIBEN COMPUESTOS, COMPOSICIONES DE DIOXOLAN FOSFAMIDATO, Y MÈTODOS PARA USAR COMPUESTOS Y COMPOSICIONES DE DIOXOLAN FOSFORAMIDATO PARA TRATAR INFECCIONES VIRALES, TALES COMO VIH.
PA20088798801A 2007-10-15 2008-10-15 Dioxalano timina fosforamidatos como agentes anti-vih. PA8798801A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US97996107P 2007-10-15 2007-10-15

Publications (1)

Publication Number Publication Date
PA8798801A1 true PA8798801A1 (es) 2009-08-26

Family

ID=40194640

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20088798801A PA8798801A1 (es) 2007-10-15 2008-10-15 Dioxalano timina fosforamidatos como agentes anti-vih.

Country Status (8)

Country Link
US (1) US20090099136A1 (es)
AR (1) AR068783A1 (es)
CL (1) CL2008003045A1 (es)
PA (1) PA8798801A1 (es)
PE (1) PE20090599A1 (es)
TW (1) TW200932753A (es)
UY (1) UY31393A1 (es)
WO (1) WO2009052050A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107312039B (zh) 2012-08-30 2019-06-25 江苏豪森药业集团有限公司 一种替诺福韦前药的制备方法
US10030044B2 (en) 2013-11-27 2018-07-24 Idenix Pharmaceuticals Llc Nucleotides for the treatment of liver cancer
JP7337539B2 (ja) * 2018-06-21 2023-09-04 メディヴィル・アクチエボラーグ 白血病療法のための塩基修飾シチジンヌクレオチド

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5276151A (en) * 1990-02-01 1994-01-04 Emory University Method of synthesis of 1,3-dioxolane nucleosides
US5204466A (en) * 1990-02-01 1993-04-20 Emory University Method and compositions for the synthesis of bch-189 and related compounds
US5179104A (en) * 1990-12-05 1993-01-12 University Of Georgia Research Foundation, Inc. Process for the preparation of enantiomerically pure β-D-(-)-dioxolane-nucleosides
EP1569659A4 (en) * 2002-12-09 2009-03-25 Univ Georgia Res Found DIOXOLAN THYMIN AND COMBINATIONS AGAINST 3TC / AZT RESISTANT HIV STRAINS
CA2623522C (en) * 2005-09-26 2015-12-08 Pharmasset, Inc. Modified 4'-nucleosides as antiviral agents

Also Published As

Publication number Publication date
CL2008003045A1 (es) 2009-10-09
PE20090599A1 (es) 2009-05-16
WO2009052050A1 (en) 2009-04-23
TW200932753A (en) 2009-08-01
US20090099136A1 (en) 2009-04-16
UY31393A1 (es) 2009-05-29
AR068783A1 (es) 2009-12-02

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