OA10239A - Distamycin a derivatives as anti-malarial agents - Google Patents

Distamycin a derivatives as anti-malarial agents Download PDF

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Publication number
OA10239A
OA10239A OA60725A OA60725A OA10239A OA 10239 A OA10239 A OA 10239A OA 60725 A OA60725 A OA 60725A OA 60725 A OA60725 A OA 60725A OA 10239 A OA10239 A OA 10239A
Authority
OA
OAPI
Prior art keywords
formula
compounds
above defined
case
group
Prior art date
Application number
OA60725A
Other languages
English (en)
Inventor
Fabio Animati
Federico Arcamone
Paolo Lombardi
Christina Rossi
Original Assignee
Menarini Farma Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Farma Ind filed Critical Menarini Farma Ind
Publication of OA10239A publication Critical patent/OA10239A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
OA60725A 1993-04-26 1995-10-24 Distamycin a derivatives as anti-malarial agents OA10239A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITFI930083A IT1263089B (it) 1993-04-26 1993-04-26 Composti pirrol-amidinici, processi di preparazione e composizioni farmaceutiche che li contengono.

Publications (1)

Publication Number Publication Date
OA10239A true OA10239A (en) 1997-10-07

Family

ID=11350437

Family Applications (1)

Application Number Title Priority Date Filing Date
OA60725A OA10239A (en) 1993-04-26 1995-10-24 Distamycin a derivatives as anti-malarial agents

Country Status (9)

Country Link
US (1) US5670534A (it)
EP (1) EP0698011A1 (it)
CN (1) CN1125437A (it)
AU (1) AU6646394A (it)
BR (1) BR9406509A (it)
CA (1) CA2161552A1 (it)
IT (1) IT1263089B (it)
OA (1) OA10239A (it)
WO (1) WO1994025436A1 (it)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9416005D0 (en) * 1994-08-08 1994-09-28 Erba Carlo Spa Peptidic compounds analogous to distamycin a and process for their preparation
AU734715B2 (en) 1996-02-26 2001-06-21 California Institute Of Technology Improved polyamides for binding in the minor groove of double stranded DNA
AU6757698A (en) 1996-02-26 1998-10-30 California Institute Of Technology Stereochemical control of the dna binding affinity, sequence specificity, and orientation-preference of chiral hairpin polyamides in the minor groove
US6090947A (en) 1996-02-26 2000-07-18 California Institute Of Technology Method for the synthesis of pyrrole and imidazole carboxamides on a solid support
US6506906B1 (en) 1996-02-26 2003-01-14 California Institute Of Technology Preparation and use of bifunctional molecules having DNA sequence binding specificity
US6635417B1 (en) 1996-07-31 2003-10-21 California Institute Of Technology Complex formation between DSDNA and oligomer of cyclic heterocycles
US6555692B1 (en) 1996-02-26 2003-04-29 California Institute Of Technology Preparation and use of bifunctional molecules having DNA sequence binding specificity
US6143901A (en) * 1996-07-31 2000-11-07 Genesoft, Inc. Complex formation between dsDNA and pyrrole imidazole polyamides
US5998140A (en) * 1996-07-31 1999-12-07 The Scripps Research Institute Complex formation between dsDNA and oligomer of cyclic heterocycles
JP2003529609A (ja) 2000-03-16 2003-10-07 ジーンソフト インコーポレイティッド 核酸結合部分を含む荷電した化合物およびその利用法
US7078536B2 (en) * 2001-03-14 2006-07-18 Genesoft Pharmaceuticals, Inc. Charged compounds comprising a nucleic acid binding moiety and uses therefor
WO2002101007A2 (en) * 2001-06-13 2002-12-19 Genesoft Pharmaceuticals, Inc Antipathogenic benzamide compounds
JP2005505508A (ja) * 2001-06-13 2005-02-24 ジーンソフト ファーマシューティカルズ インコーポレイテッド 抗感染活性を有するベンゾチオフェン化合物
ITTO20010633A1 (it) 2001-07-02 2003-01-02 Univ Ferrara Nuovo impiego di poliammidi eterocicliche e benzoeterocicliche strutturalmente correlate all'antibiotico naturale distamicina a.
WO2004012736A1 (en) 2002-08-02 2004-02-12 Genesoft Pharmaceuticals, Inc. Biaryl compounds having anti-infective activity
EP1562931A2 (en) * 2002-10-25 2005-08-17 Genesoft Pharmaceuticals, Inc. Anti-infective biaryl compounds
JP2006509027A (ja) 2002-12-10 2006-03-16 オーシェント ファーマシューティカルズ コーポレーション (ピロールカルボキサミド)−(ベンズアミド)−(イミダゾールカルボキサミド)モチーフを有する抗菌化合物
ITMI20031015A1 (it) * 2003-05-20 2004-11-21 Naxospharma S R L Poli-(amminopirrolcarbossammidi) per uso nella profilassi e nel trattamento delle endoparassitosi animali e loro composizioni con ciclodestrine.
ITMI20031111A1 (it) * 2003-06-03 2004-12-04 Naxospharma Srl Processo per la sintesi della distramicina e analoghi poli-4-(1-metilpirrolo)-2-carbossiammidici.
US7094791B2 (en) * 2003-07-31 2006-08-22 Avalon Pharmaceuticals, Inc. Derivatives of 3-hydroxy-pyrrole-2,4-dicarboxylic acid and uses thereof
SG155222A1 (en) * 2004-08-13 2009-09-30 Genentech Inc Thiazole based inhibitors of atp-utilizing enzymes
GB0619325D0 (en) * 2006-09-30 2006-11-08 Univ Strathclyde New compounds
US8494795B2 (en) * 2008-05-05 2013-07-23 Schweitzer Engineering Laboratories Inc Apparatus and method for estimating synchronized phasors at predetermined times referenced to a common time standard in an electrical system

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1243389B (it) * 1990-11-22 1994-06-10 Menarini Farma Ind Derivati poliaminopirrolcarbossiamidici, processi di preparazione e composizioni farmaceutiche che li contengono.
IT1262921B (it) * 1992-01-10 1996-07-22 Federico Arcamone Agenti antitumorali analoghi di oligopeptidi pirrol-amidinici retroversi processi di preparazione e prodotti farmaceutici che li contengono

Also Published As

Publication number Publication date
ITFI930083A0 (it) 1993-04-26
AU6646394A (en) 1994-11-21
US5670534A (en) 1997-09-23
CA2161552A1 (en) 1994-11-10
EP0698011A1 (en) 1996-02-28
WO1994025436A1 (en) 1994-11-10
BR9406509A (pt) 1996-01-09
CN1125437A (zh) 1996-06-26
IT1263089B (it) 1996-07-24
ITFI930083A1 (it) 1994-10-26

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