OA04785A - Esters d'amino acides. - Google Patents
Esters d'amino acides.Info
- Publication number
- OA04785A OA04785A OA55305A OA55305A OA04785A OA 04785 A OA04785 A OA 04785A OA 55305 A OA55305 A OA 55305A OA 55305 A OA55305 A OA 55305A OA 04785 A OA04785 A OA 04785A
- Authority
- OA
- OAPI
- Prior art keywords
- amino acid
- acid esters
- esters
- amino
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/40—2,5-Pyrrolidine-diones
- C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
- C07D207/444—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
- C07D207/448—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
- C07D207/452—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide with hydrocarbon radicals, substituted by hetero atoms, directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
- C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/44—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
- C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Indole Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40060973A | 1973-09-25 | 1973-09-25 | |
US05/482,102 US3983138A (en) | 1973-09-25 | 1974-06-25 | Amino acid esters |
AU30912/77A AU516398B2 (en) | 1973-09-25 | 1977-11-23 | Esters of methyl-3, 4-dihydroxyphenyl alanine |
Publications (1)
Publication Number | Publication Date |
---|---|
OA04785A true OA04785A (fr) | 1980-08-31 |
Family
ID=27153356
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
OA55305A OA04785A (fr) | 1973-09-25 | 1974-09-23 | Esters d'amino acides. |
Country Status (13)
Country | Link |
---|---|
US (1) | US3983138A (de) |
JP (1) | JPS5062944A (de) |
AT (1) | AT343639B (de) |
AU (1) | AU516398B2 (de) |
BE (1) | BE820253A (de) |
CA (1) | CA1057767A (de) |
CH (1) | CH606027A5 (de) |
DE (1) | DE2445584C3 (de) |
FR (1) | FR2244488B1 (de) |
GB (1) | GB1447599A (de) |
LU (1) | LU70966A1 (de) |
NL (1) | NL157010B (de) |
OA (1) | OA04785A (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4198413A (en) * | 1973-09-25 | 1980-04-15 | Merck & Co., Inc. | Amino acid esters |
SE7605911L (sv) * | 1975-06-11 | 1976-12-12 | Merck & Co Inc | Forbettrat forfarande for framstellning av estrar av alfa-metyl-3,4-dihydroxifenylalanin |
FR2365341A1 (fr) * | 1976-09-28 | 1978-04-21 | Synthelabo | Derives de l'acide l-(phenyl-3 amino-2 propionyloxy)-2 acetique |
US4120971A (en) * | 1977-03-01 | 1978-10-17 | Merck & Co., Inc. | Novel N-carboxy-alpha-amino acid anhydrides |
GB1583602A (en) * | 1977-05-26 | 1981-01-28 | Sterwin Ag | N-acetyl-para-aminophenyl-n'-acetyl-amino-thioalkanoic acid ester derivatives |
US4401676A (en) * | 1977-06-01 | 1983-08-30 | Merck & Co., Inc. | Novel α-amino acids |
US4271187A (en) * | 1978-06-05 | 1981-06-02 | Merck & Co., Inc. | Substituted phenyl alanine antihypertensive agents |
IL57609A (en) * | 1979-06-21 | 1983-05-15 | Yeda Res & Dev | Pharmaceutical compositions for the treatment of sickle cell disease comprising p-nitrobenzyl esters or amides of aromatic or hydrophobic aminoacids |
US4404392A (en) * | 1981-11-16 | 1983-09-13 | Merck & Co., Inc. | Resolution of α-pivaloyloxyethyl-(S)-3-(3,4-dihydroxyphenyl)-2-methylalantinate into its α and β isomers |
US4360533A (en) * | 1981-12-14 | 1982-11-23 | Merck & Co., Inc. | Glyceryl ester of 1-methyl-2-(3,4-dihydroxyphenyl)alanine |
US4440942A (en) * | 1982-03-01 | 1984-04-03 | Merck & Co., Inc. | Crystalline diastereomeric L-alpha-methyldopa POE ester and process for its preparation |
PT79107B (en) * | 1983-08-29 | 1986-11-14 | Merck & Co Inc | Process for preparing crystalline salts of l or (s)-3-(3,4-dihydroxyphenyl)-2-methylalanine esters |
US4670578A (en) * | 1983-08-29 | 1987-06-02 | Merck & Co., Inc. | Process for crystalline salts of L or (S)-3-(3,4-dihydroxyphenyl)-2-methylalanine esters |
US4914222A (en) * | 1983-08-29 | 1990-04-03 | Merck & Co., Inc. | Crystalline salts of L or (S)-3-(3,4-dihydroxyphenyl)-2-methylalanine esters and process |
JPH02138A (ja) * | 1987-09-18 | 1990-01-05 | Banyu Pharmaceut Co Ltd | L‐ドーパ誘導体 |
ZA200610042B (en) | 2004-06-04 | 2008-06-25 | Xenoport Inc | Levodopa prodrugs, and compositions and uses thereof |
WO2007067495A2 (en) | 2005-12-05 | 2007-06-14 | Xenoport, Inc. | Levodopa prodrug mesylate, compositions thereof, and uses thereof |
WO2008076458A1 (en) | 2006-12-21 | 2008-06-26 | Xenoport, Inc. | Levodopa dimethyl-substituted diester prodrugs, compositions, and methods of use |
US7829592B2 (en) | 2006-12-21 | 2010-11-09 | Xenoport, Inc. | Catechol protected levodopa diester prodrugs, compositions, and methods of use |
US8399513B2 (en) | 2008-10-20 | 2013-03-19 | Xenoport, Inc. | Levodopa prodrug mesylate hydrate |
CN102186804A (zh) | 2008-10-20 | 2011-09-14 | 克塞诺波特公司 | 合成左旋多巴酯前药的方法 |
US9605112B2 (en) * | 2009-10-11 | 2017-03-28 | Rutgers, The State University Of New Jersey | Biocompatible polymers for medical devices |
ES2565644T3 (es) | 2009-11-09 | 2016-04-06 | Xenoport, Inc. | Composiciones farmacéuticas y formas de dosificación oral de un pre medicamento de levodopa y los métodos de utilización |
CN103694127B (zh) * | 2013-12-30 | 2015-04-01 | 上海交通大学 | 链霉菌属菌种所产的化合物及该化合物的制备方法和应用 |
CN113176369B (zh) * | 2021-04-09 | 2022-05-31 | 浙江省海洋生态环境监测中心 | 一种海洋贝类产品中有机锡的测定方法 |
-
1974
- 1974-06-25 US US05/482,102 patent/US3983138A/en not_active Expired - Lifetime
- 1974-09-10 NL NL7412030.A patent/NL157010B/xx not_active IP Right Cessation
- 1974-09-16 FR FR7431204A patent/FR2244488B1/fr not_active Expired
- 1974-09-18 GB GB4071474A patent/GB1447599A/en not_active Expired
- 1974-09-19 CA CA209,616A patent/CA1057767A/en not_active Expired
- 1974-09-19 CH CH1273474A patent/CH606027A5/xx not_active IP Right Cessation
- 1974-09-23 OA OA55305A patent/OA04785A/xx unknown
- 1974-09-23 LU LU70966A patent/LU70966A1/xx unknown
- 1974-09-24 AT AT767874A patent/AT343639B/de not_active IP Right Cessation
- 1974-09-24 BE BE148813A patent/BE820253A/xx not_active IP Right Cessation
- 1974-09-24 DE DE2445584A patent/DE2445584C3/de not_active Expired
- 1974-09-25 JP JP49109657A patent/JPS5062944A/ja active Pending
-
1977
- 1977-11-23 AU AU30912/77A patent/AU516398B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
NL157010B (nl) | 1978-06-15 |
AU3091277A (en) | 1978-05-04 |
GB1447599A (en) | 1976-08-25 |
LU70966A1 (de) | 1975-06-16 |
DE2445584B2 (de) | 1978-08-31 |
DE2445584A1 (de) | 1975-03-27 |
US3983138A (en) | 1976-09-28 |
FR2244488B1 (de) | 1978-06-30 |
CH606027A5 (de) | 1978-10-13 |
FR2244488A1 (de) | 1975-04-18 |
BE820253A (fr) | 1975-03-24 |
CA1057767A (en) | 1979-07-03 |
AT343639B (de) | 1978-06-12 |
AU516398B2 (en) | 1981-06-04 |
DE2445584C3 (de) | 1979-05-10 |
ATA767874A (de) | 1977-10-15 |
AU7336674A (en) | 1976-03-25 |
JPS5062944A (de) | 1975-05-29 |
NL7412030A (nl) | 1975-03-27 |
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