OA02583A - Procédé de préparation de bis-benzimidazoles porteurs de substituants basiques. - Google Patents

Procédé de préparation de bis-benzimidazoles porteurs de substituants basiques.

Info

Publication number
OA02583A
OA02583A OA52892A OA52892A OA02583A OA 02583 A OA02583 A OA 02583A OA 52892 A OA52892 A OA 52892A OA 52892 A OA52892 A OA 52892A OA 02583 A OA02583 A OA 02583A
Authority
OA
OAPI
Prior art keywords
bis
preparation
basic substituents
carrying basic
benzimidazoles
Prior art date
Application number
OA52892A
Other languages
English (en)
French (fr)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of OA02583A publication Critical patent/OA02583A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/20—Two benzimidazolyl-2 radicals linked together directly or via a hydrocarbon or substituted hydrocarbon radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
OA52892A 1966-04-01 1967-04-01 Procédé de préparation de bis-benzimidazoles porteurs de substituants basiques. OA02583A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF0048833 1966-04-01

Publications (1)

Publication Number Publication Date
OA02583A true OA02583A (fr) 1970-05-05

Family

ID=7102516

Family Applications (1)

Application Number Title Priority Date Filing Date
OA52892A OA02583A (fr) 1966-04-01 1967-04-01 Procédé de préparation de bis-benzimidazoles porteurs de substituants basiques.

Country Status (9)

Country Link
US (1) US3538097A (de)
BE (1) BE696499A (de)
CH (2) CH533124A (de)
DE (1) DE1670684A1 (de)
FR (2) FR1519964A (de)
GB (1) GB1186723A (de)
MY (1) MY7100120A (de)
NL (1) NL6704539A (de)
OA (1) OA02583A (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091101A (en) * 1977-06-15 1978-05-23 Merck & Co., Inc. 6-(1-Piperazinyl)quinoxaline
DE3611343A1 (de) * 1986-04-04 1987-10-08 Boehringer Mannheim Gmbh Heterocyclisch substituierte benzimidazole, verfahren zu ihrer herstellung, arzneimittel sowie zwischenprodukte
EP0777656B1 (de) * 1994-08-26 2004-04-14 Auckland Division Cancer Society Of New Zealand (Incorporated) Neue auf dna gerichtete alkylierungsmittel
AU695936B2 (en) * 1994-08-26 1998-08-27 Auckland Division Cancer Society Of New Zealand Inc Novel dna-targeted alkylating agents
US5767142A (en) * 1996-03-20 1998-06-16 Rutgers, The State University Of New Jersey Trisbenzimidazoles useful as topoisomerase I inhibitors
US5807874A (en) * 1995-05-17 1998-09-15 Rutgers, The State University Of New Jersey Trisbenzimidazoles useful as topoisomerase I inhibitors
AUPN449295A0 (en) 1995-07-28 1995-08-24 Inner And Eastern Health Care Network, The Radioprotectors
JP2001501197A (ja) * 1996-09-23 2001-01-30 ルトガーズ，ザ ステイト ユニバーシティ オブ ニュージャージー 抗―腫瘍剤としての置換された複素環式化合物類
US6140328A (en) 1997-12-12 2000-10-31 Rutgers, The State University Of New Jersey Heterocyclic cytotoxic agents
PL341539A1 (en) * 1997-12-31 2001-04-23 Rutgers Heterocyclic toxins of topoisomerases
US6063801A (en) 1998-02-12 2000-05-16 Rutgers, The State University Of New Jersey Heterocyclic topoisomerase poisons
US6740650B2 (en) 1999-10-29 2004-05-25 Rutgers, The State University Of New Jersey Heterocyclic cytotoxic agents
EP1453812B1 (de) 2001-11-14 2008-08-20 Rutgers, The State University Cytotoxische mittel
WO2003047505A2 (en) * 2001-11-14 2003-06-12 Rutgers, The State University Topoisomerase poison agents
WO2003041660A2 (en) * 2001-11-14 2003-05-22 Rutgers, The State University Solubilized topoisomerase poisons
EP1453507B1 (de) * 2001-11-14 2009-03-04 Rutgers, The State University Solubilisierte topoisomerase-gift-mittel
US20050119251A1 (en) * 2001-12-21 2005-06-02 Jian-Min Fu Nicotinamide derivatives and their use as therapeutic agents
AU2003268075A1 (en) * 2002-08-09 2004-02-25 Edmond J. Lavoie Nitro and amino substituted dibenzonaphthyridines as topoisomerase agents
WO2004014918A1 (en) 2002-08-09 2004-02-19 Rutgers, The State University Nitro and amino substituted topoisomerase agents
WO2004014862A1 (en) * 2002-08-09 2004-02-19 Rutgers, The State University Nitro and amino substituted heterocycles as topoisomerase i targeting agents
CA2510337C (en) * 2002-11-12 2013-01-08 Rutgers, The State University Of New Jersey Topoisomerase-targeting agents
US8071603B2 (en) 2004-09-20 2011-12-06 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
US7592343B2 (en) * 2004-09-20 2009-09-22 Xenon Pharmaceuticals Inc. Pyridazine-piperazine compounds and their use as stearoyl-CoA desaturase inhibitors
BRPI0611187A2 (pt) * 2005-06-03 2010-08-24 Xenon Pharmaceuticals Inc derivados aminotiazàis como inibidores da estearoil-coa desaturase humana
JP5639763B2 (ja) * 2006-12-21 2014-12-10 ピーター・マッカラム・キャンサー・インスティチュート 放射線防護剤および関連する方法
GB0821913D0 (en) 2008-12-02 2009-01-07 Price & Co Antibacterial compounds
PT2403856E (pt) 2009-03-06 2013-03-25 Univ Rutgers Derivados de metilendioxibenzo[i]fenantridina utilizados para tratar o cancro
WO2010127363A1 (en) 2009-05-01 2010-11-04 Rutgers, The State University Of New Jersey Toposiomerase inhibitors
JP5712524B2 (ja) * 2009-10-28 2015-05-07 Jsr株式会社 液晶配向剤および液晶表示素子
WO2011151621A1 (en) * 2010-06-01 2011-12-08 Summit Corporation Plc Compounds for the treatment of clostridium difficile associated disease
JP6463631B2 (ja) * 2011-06-09 2019-02-06 ライゼン・ファーマシューティカルズ・エスアー Ｇｐｒ−１１９のモジュレータとしての新規化合物
GB201506658D0 (en) 2015-04-20 2015-06-03 Cellcentric Ltd Pharmaceutical compounds
GB201506660D0 (en) 2015-04-20 2015-06-03 Cellcentric Ltd Pharmaceutical compounds
CA3011672C (en) * 2016-01-23 2022-11-01 Vibha Tandon Broad spectrum antibacterial activity of bisbenzimidazoles targeting topoisomerase ia
CN109219610A (zh) 2016-04-04 2019-01-15 新泽西州立拉特格斯大学 拓扑异构酶毒物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3103403A (en) * 1963-09-10 Dyeing of polyester fibers with com-
US2980690A (en) * 1957-08-30 1961-04-18 Ciba Pharm Prod Inc New basically substituted benzylbenzimidazoles
US3072661A (en) * 1960-08-24 1963-01-08 Interchem Corp New process for improved bis-imidazole vat dyestuff pigments
US3133056A (en) * 1961-05-15 1964-05-12 May & Baker Ltd N-phenylpiperazine derivatives of tetrahydrobenzodiazepines
NL128199C (de) * 1962-04-21
NL135043C (de) * 1963-10-11
GB1122988A (en) * 1964-10-22 1968-08-07 Fisons Pest Control Ltd Benzimidazole derivatives
US3336191A (en) * 1966-03-11 1967-08-15 Smith Kline French Lab Anthelmintic 2-amidobenzimidazoles
US3362956A (en) * 1965-08-19 1968-01-09 Sterling Drug Inc 1-[(heterocyclyl)-lower-alkyl]-4-substituted-piperazines

Also Published As

Publication number Publication date
FR6681M (de) 1969-02-03
NL6704539A (de) 1967-10-02
BE696499A (de) 1967-10-03
CH525902A (de) 1972-07-31
MY7100120A (en) 1971-12-31
US3538097A (en) 1970-11-03
FR1519964A (fr) 1968-04-05
CH533124A (de) 1973-01-31
GB1186723A (en) 1970-04-02
DE1670684A1 (de) 1970-12-03

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