CH525902A - Verfahren zur Herstellung von basisch substituierten Bis-benzimidazol-derivaten - Google Patents

Verfahren zur Herstellung von basisch substituierten Bis-benzimidazol-derivaten

Info

Publication number
CH525902A
CH525902A CH429167A CH429167A CH525902A CH 525902 A CH525902 A CH 525902A CH 429167 A CH429167 A CH 429167A CH 429167 A CH429167 A CH 429167A CH 525902 A CH525902 A CH 525902A
Authority
CH
Switzerland
Prior art keywords
preparation
benzimidazole derivatives
substituted bis
basic substituted
basic
Prior art date
Application number
CH429167A
Other languages
English (en)
Inventor
Loewe Heinz
Urbanietz Josef
Laemmler Georg
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Priority to CH594172A priority Critical patent/CH533124A/de
Publication of CH525902A publication Critical patent/CH525902A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/20—Two benzimidazolyl-2 radicals linked together directly or via a hydrocarbon or substituted hydrocarbon radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH429167A 1966-04-01 1967-03-28 Verfahren zur Herstellung von basisch substituierten Bis-benzimidazol-derivaten CH525902A (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CH594172A CH533124A (de) 1966-04-01 1967-03-28 Verfahren zur Herstellung von basisch substituierten Bis-benzimidazol-derivaten

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF0048833 1966-04-01

Publications (1)

Publication Number Publication Date
CH525902A true CH525902A (de) 1972-07-31

Family

ID=7102516

Family Applications (2)

Application Number Title Priority Date Filing Date
CH594172A CH533124A (de) 1966-04-01 1967-03-28 Verfahren zur Herstellung von basisch substituierten Bis-benzimidazol-derivaten
CH429167A CH525902A (de) 1966-04-01 1967-03-28 Verfahren zur Herstellung von basisch substituierten Bis-benzimidazol-derivaten

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH594172A CH533124A (de) 1966-04-01 1967-03-28 Verfahren zur Herstellung von basisch substituierten Bis-benzimidazol-derivaten

Country Status (9)

Country Link
US (1) US3538097A (de)
BE (1) BE696499A (de)
CH (2) CH533124A (de)
DE (1) DE1670684A1 (de)
FR (2) FR1519964A (de)
GB (1) GB1186723A (de)
MY (1) MY7100120A (de)
NL (1) NL6704539A (de)
OA (1) OA02583A (de)

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US4091101A (en) * 1977-06-15 1978-05-23 Merck & Co., Inc. 6-(1-Piperazinyl)quinoxaline
DE3611343A1 (de) * 1986-04-04 1987-10-08 Boehringer Mannheim Gmbh Heterocyclisch substituierte benzimidazole, verfahren zu ihrer herstellung, arzneimittel sowie zwischenprodukte
WO1996006831A1 (en) * 1994-08-26 1996-03-07 Auckland Division Cancer Society Of New Zealand Inc. Novel dna-targeted alkylating agents
AU695936B2 (en) * 1994-08-26 1998-08-27 Auckland Division Cancer Society Of New Zealand Inc Novel dna-targeted alkylating agents
US5767142A (en) * 1996-03-20 1998-06-16 Rutgers, The State University Of New Jersey Trisbenzimidazoles useful as topoisomerase I inhibitors
US5807874A (en) * 1995-05-17 1998-09-15 Rutgers, The State University Of New Jersey Trisbenzimidazoles useful as topoisomerase I inhibitors
AUPN449295A0 (en) 1995-07-28 1995-08-24 Inner And Eastern Health Care Network, The Radioprotectors
US5981541A (en) * 1996-09-23 1999-11-09 Rutgers, The State University Of New Jersey Substituted heterocycles as anti-tumor agents
US6140328A (en) * 1997-12-12 2000-10-31 Rutgers, The State University Of New Jersey Heterocyclic cytotoxic agents
CN1299358A (zh) 1997-12-31 2001-06-13 新泽西州州立大学(拉特格斯) 杂环拓扑异构酶毒性剂
IL137351A0 (en) 1998-02-12 2001-07-24 Univ Rutgers Heterocyclic topoisomerase poisons
US6740650B2 (en) 1999-10-29 2004-05-25 Rutgers, The State University Of New Jersey Heterocyclic cytotoxic agents
AU2002364953A1 (en) * 2001-11-14 2003-06-17 Edmond J. Lavoie Topoisomerase poison agents
AU2002365161B2 (en) * 2001-11-14 2008-07-03 Rutgers, The State University Solubilized topoisomerase poison agents
EP1453812B1 (de) * 2001-11-14 2008-08-20 Rutgers, The State University Cytotoxische mittel
PT1465625E (pt) * 2001-11-14 2010-03-09 Univ Rutgers Venenos de topoisomerase solubilizados
US20050119251A1 (en) * 2001-12-21 2005-06-02 Jian-Min Fu Nicotinamide derivatives and their use as therapeutic agents
US6992088B2 (en) * 2002-08-09 2006-01-31 Rutgers, The State University Of New Jersey Nitro and amino substituted heterocycles as topoisomerase I targeting agents
AU2003268075A1 (en) * 2002-08-09 2004-02-25 Edmond J. Lavoie Nitro and amino substituted dibenzonaphthyridines as topoisomerase agents
AU2003265406A1 (en) 2002-08-09 2004-02-25 Edmond J. Lavoie Nitro and amino substituted topoisomerase agents
AU2003290818A1 (en) * 2002-11-12 2004-06-03 Edmond J. Lavoie Topoisomerase-targeting agents
AR051093A1 (es) * 2004-09-20 2006-12-20 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de estearoil-coa desaturasa
MX2007003332A (es) 2004-09-20 2007-06-05 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de estearoil-coa-desaturasa.
EP2029138A1 (de) * 2005-06-03 2009-03-04 Xenon Pharmaceuticals Inc. Aminothiazolderivate als humane stearoyl-coa desaturasehemmer
PT2114896E (pt) * 2006-12-21 2015-11-04 Peter Maccallum Cancer Inst Compostos radio-protetores e métodos relacionados
GB0821913D0 (en) 2008-12-02 2009-01-07 Price & Co Antibacterial compounds
EP2403856B1 (de) 2009-03-06 2012-12-19 Rutgers, The State University of New Jersey Zur behandlung von krebs verwendete methylendioxybenzo[i]phenanthridinderivate
WO2010127363A1 (en) 2009-05-01 2010-11-04 Rutgers, The State University Of New Jersey Toposiomerase inhibitors
JP5712524B2 (ja) * 2009-10-28 2015-05-07 Jsr株式会社 液晶配向剤および液晶表示素子
WO2011151621A1 (en) * 2010-06-01 2011-12-08 Summit Corporation Plc Compounds for the treatment of clostridium difficile associated disease
AU2012267556B9 (en) 2011-06-09 2017-05-11 Rhizen Pharmaceuticals Sa Novel compounds as modulators of GPR-119
GB201506660D0 (en) 2015-04-20 2015-06-03 Cellcentric Ltd Pharmaceutical compounds
GB201506658D0 (en) 2015-04-20 2015-06-03 Cellcentric Ltd Pharmaceutical compounds
WO2017125944A1 (en) * 2016-01-23 2017-07-27 Jawaharlal Nehru University (Jnu) Broad spectrum antibacterial activity of novel bisbenzimidazoles targeting topoisomerase ia and the synergistic composition of bisbenzimidazole with efflux pump inhibitors against pathogenic bacteria
JP2019515025A (ja) 2016-04-04 2019-06-06 ラトガース ザ ステイト ユニバーシティー オブ ニュージャージー トポイソメラーゼ毒

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3103403A (en) * 1963-09-10 Dyeing of polyester fibers with com-
US2980690A (en) * 1957-08-30 1961-04-18 Ciba Pharm Prod Inc New basically substituted benzylbenzimidazoles
US3072661A (en) * 1960-08-24 1963-01-08 Interchem Corp New process for improved bis-imidazole vat dyestuff pigments
US3133056A (en) * 1961-05-15 1964-05-12 May & Baker Ltd N-phenylpiperazine derivatives of tetrahydrobenzodiazepines
BE631368A (de) * 1962-04-21
NL135043C (de) * 1963-10-11
GB1122988A (en) * 1964-10-22 1968-08-07 Fisons Pest Control Ltd Benzimidazole derivatives
US3336191A (en) * 1966-03-11 1967-08-15 Smith Kline French Lab Anthelmintic 2-amidobenzimidazoles
US3362956A (en) * 1965-08-19 1968-01-09 Sterling Drug Inc 1-[(heterocyclyl)-lower-alkyl]-4-substituted-piperazines

Also Published As

Publication number Publication date
CH533124A (de) 1973-01-31
GB1186723A (en) 1970-04-02
US3538097A (en) 1970-11-03
DE1670684A1 (de) 1970-12-03
NL6704539A (de) 1967-10-02
FR1519964A (fr) 1968-04-05
MY7100120A (en) 1971-12-31
OA02583A (fr) 1970-05-05
BE696499A (de) 1967-10-03
FR6681M (de) 1969-02-03

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Legal Events

Date Code Title Description
PL Patent ceased