CH525902A - Verfahren zur Herstellung von basisch substituierten Bis-benzimidazol-derivaten - Google Patents

Verfahren zur Herstellung von basisch substituierten Bis-benzimidazol-derivaten

Info

Publication number
CH525902A
CH525902A CH429167A CH429167A CH525902A CH 525902 A CH525902 A CH 525902A CH 429167 A CH429167 A CH 429167A CH 429167 A CH429167 A CH 429167A CH 525902 A CH525902 A CH 525902A
Authority
CH
Switzerland
Prior art keywords
preparation
benzimidazole derivatives
substituted bis
basic substituted
basic
Prior art date
Application number
CH429167A
Other languages
English (en)
Inventor
Loewe Heinz
Urbanietz Josef
Laemmler Georg
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Priority to CH594172A priority Critical patent/CH533124A/de
Publication of CH525902A publication Critical patent/CH525902A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/20—Two benzimidazolyl-2 radicals linked together directly or via a hydrocarbon or substituted hydrocarbon radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH429167A 1966-04-01 1967-03-28 Verfahren zur Herstellung von basisch substituierten Bis-benzimidazol-derivaten CH525902A (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CH594172A CH533124A (de) 1966-04-01 1967-03-28 Verfahren zur Herstellung von basisch substituierten Bis-benzimidazol-derivaten

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF0048833 1966-04-01

Publications (1)

Publication Number Publication Date
CH525902A true CH525902A (de) 1972-07-31

Family

ID=7102516

Family Applications (2)

Application Number Title Priority Date Filing Date
CH594172A CH533124A (de) 1966-04-01 1967-03-28 Verfahren zur Herstellung von basisch substituierten Bis-benzimidazol-derivaten
CH429167A CH525902A (de) 1966-04-01 1967-03-28 Verfahren zur Herstellung von basisch substituierten Bis-benzimidazol-derivaten

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH594172A CH533124A (de) 1966-04-01 1967-03-28 Verfahren zur Herstellung von basisch substituierten Bis-benzimidazol-derivaten

Country Status (9)

Country Link
US (1) US3538097A (de)
BE (1) BE696499A (de)
CH (2) CH533124A (de)
DE (1) DE1670684A1 (de)
FR (2) FR1519964A (de)
GB (1) GB1186723A (de)
MY (1) MY7100120A (de)
NL (1) NL6704539A (de)
OA (1) OA02583A (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091101A (en) * 1977-06-15 1978-05-23 Merck & Co., Inc. 6-(1-Piperazinyl)quinoxaline
DE3611343A1 (de) * 1986-04-04 1987-10-08 Boehringer Mannheim Gmbh Heterocyclisch substituierte benzimidazole, verfahren zu ihrer herstellung, arzneimittel sowie zwischenprodukte
EP0777656B1 (de) * 1994-08-26 2004-04-14 Auckland Division Cancer Society Of New Zealand (Incorporated) Neue auf dna gerichtete alkylierungsmittel
AU695936B2 (en) * 1994-08-26 1998-08-27 Auckland Division Cancer Society Of New Zealand Inc Novel dna-targeted alkylating agents
US5807874A (en) * 1995-05-17 1998-09-15 Rutgers, The State University Of New Jersey Trisbenzimidazoles useful as topoisomerase I inhibitors
US5767142A (en) * 1996-03-20 1998-06-16 Rutgers, The State University Of New Jersey Trisbenzimidazoles useful as topoisomerase I inhibitors
AUPN449295A0 (en) * 1995-07-28 1995-08-24 Inner And Eastern Health Care Network, The Radioprotectors
CZ102499A3 (cs) * 1996-09-23 1999-09-15 Rutgers, The State University Of New Jersey Heterocyklické sloučeniny a farmaceutický prostředek
US6140328A (en) 1997-12-12 2000-10-31 Rutgers, The State University Of New Jersey Heterocyclic cytotoxic agents
WO1999033824A1 (en) * 1997-12-31 1999-07-08 Rutgers, The State University Of New Jersey Heterocyclic topoisomerase poisons
US6063801A (en) 1998-02-12 2000-05-16 Rutgers, The State University Of New Jersey Heterocyclic topoisomerase poisons
US6740650B2 (en) 1999-10-29 2004-05-25 Rutgers, The State University Of New Jersey Heterocyclic cytotoxic agents
SI1465625T1 (sl) * 2001-11-14 2010-06-30 Univ Rutgers Solubilizirani topoizomerazni strupi
DE60228484D1 (de) 2001-11-14 2008-10-02 Univ Rutgers Cytotoxische mittel
MXPA04004607A (es) * 2001-11-14 2004-09-10 Univ Rutgers Agentes de venenos de topoisomerasa solubilizados.
AU2002364953A1 (en) * 2001-11-14 2003-06-17 Edmond J. Lavoie Topoisomerase poison agents
US20050119251A1 (en) * 2001-12-21 2005-06-02 Jian-Min Fu Nicotinamide derivatives and their use as therapeutic agents
WO2004014918A1 (en) 2002-08-09 2004-02-19 Rutgers, The State University Nitro and amino substituted topoisomerase agents
AU2003268075A1 (en) * 2002-08-09 2004-02-25 Edmond J. Lavoie Nitro and amino substituted dibenzonaphthyridines as topoisomerase agents
US6992088B2 (en) * 2002-08-09 2006-01-31 Rutgers, The State University Of New Jersey Nitro and amino substituted heterocycles as topoisomerase I targeting agents
AU2003290818A1 (en) * 2002-11-12 2004-06-03 Edmond J. Lavoie Topoisomerase-targeting agents
EP1804799B1 (de) * 2004-09-20 2013-08-21 Xenon Pharmaceuticals Inc. Heterozyklische Derivate und ihre Verwendung als Stearoyl-Coa-Desaturase-Inhibitoren
CA2580856A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
MX2007015216A (es) * 2005-06-03 2008-02-22 Xenon Pharmaceuticals Inc Derivados de aminotiazol y sus usos como agentes terapeuticos.
JP5639763B2 (ja) * 2006-12-21 2014-12-10 ピーター・マッカラム・キャンサー・インスティチュート 放射線防護剤および関連する方法
GB0821913D0 (en) 2008-12-02 2009-01-07 Price & Co Antibacterial compounds
ES2401563T3 (es) 2009-03-06 2013-04-22 Rutgers, The State University Of New Jersey Derivados de metilendioxibenzo [I]fenantridina usados para tratar el cáncer
WO2010127363A1 (en) 2009-05-01 2010-11-04 Rutgers, The State University Of New Jersey Toposiomerase inhibitors
JP5712524B2 (ja) * 2009-10-28 2015-05-07 Jsr株式会社 液晶配向剤および液晶表示素子
WO2011151621A1 (en) * 2010-06-01 2011-12-08 Summit Corporation Plc Compounds for the treatment of clostridium difficile associated disease
ES2602813T3 (es) * 2011-06-09 2017-02-22 Rhizen Pharmaceuticals S.A. Nuevos compuestos como moduladores de GPR-119
GB201506660D0 (en) 2015-04-20 2015-06-03 Cellcentric Ltd Pharmaceutical compounds
GB201506658D0 (en) 2015-04-20 2015-06-03 Cellcentric Ltd Pharmaceutical compounds
US11434227B2 (en) * 2016-01-23 2022-09-06 Vibha TANDON Broad spectrum antibacterial activity of novel bisbenzimidazoles targeting topoisomerase IA and the synergistic composition of bisbenzimidazole with efflux pump inhibitors against pathogenic bacteria
WO2017176648A1 (en) 2016-04-04 2017-10-12 Rutgers, The State University Of New Jersey Topoisomerase poisons

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3103403A (en) * 1963-09-10 Dyeing of polyester fibers with com-
US2980690A (en) * 1957-08-30 1961-04-18 Ciba Pharm Prod Inc New basically substituted benzylbenzimidazoles
US3072661A (en) * 1960-08-24 1963-01-08 Interchem Corp New process for improved bis-imidazole vat dyestuff pigments
US3133056A (en) * 1961-05-15 1964-05-12 May & Baker Ltd N-phenylpiperazine derivatives of tetrahydrobenzodiazepines
BE631368A (de) * 1962-04-21
NL135043C (de) * 1963-10-11
GB1122988A (en) * 1964-10-22 1968-08-07 Fisons Pest Control Ltd Benzimidazole derivatives
US3336191A (en) * 1966-03-11 1967-08-15 Smith Kline French Lab Anthelmintic 2-amidobenzimidazoles
US3362956A (en) * 1965-08-19 1968-01-09 Sterling Drug Inc 1-[(heterocyclyl)-lower-alkyl]-4-substituted-piperazines

Also Published As

Publication number Publication date
GB1186723A (en) 1970-04-02
FR6681M (de) 1969-02-03
OA02583A (fr) 1970-05-05
MY7100120A (en) 1971-12-31
US3538097A (en) 1970-11-03
BE696499A (de) 1967-10-03
DE1670684A1 (de) 1970-12-03
CH533124A (de) 1973-01-31
FR1519964A (fr) 1968-04-05
NL6704539A (de) 1967-10-02

Similar Documents

Publication Publication Date Title
CH525902A (de) Verfahren zur Herstellung von basisch substituierten Bis-benzimidazol-derivaten
CH492676A (de) Verfahren zur Herstellung von 1-Phenyl-2-aminoäthanol-Derivaten
CH518940A (de) Verfahren zur Herstellung von Isochinuclidin-Derivaten
CH491119A (de) Verfahren zur Herstellung von N6-Aralkyl-adenosin-derivaten
CH489517A (de) Verfahren zur Herstellung von N-Acylsydnoniminderivaten
CH541580A (de) Verfahren zur Herstellung von Bis-thioureidobenzol-derivaten
CH529145A (de) Verfahren zur Herstellung von 1-Aminoalkylbenzodiazepinderivaten
CH508632A (de) Verfahren zur Herstellung von Imidazolderivaten
CH482720A (de) Verfahren zur Herstellung von Benzimidazolderivaten
CH505836A (de) Verfahren zur Herstellung von basisch substituierten Alkoxyanthranilamiden
CH437318A (de) Verfahren zur Herstellung von Benzimidazolderivaten
CH518255A (de) Verfahren zur Herstellung von Diarylcyclopropan-Derivaten
AT273953B (de) Verfahren zur Herstellung von v-Triazolyl-cumarinderivaten
CH457452A (de) Verfahren zur Herstellung von basisch substituierten Alkylxanthinderivaten
CH486484A (de) Verfahren zur Herstellung von Dibenzothiazinderivaten
CH487899A (de) Verfahren zur Herstellung von Nitroimidazolderivaten
CH481901A (de) Verfahren zur Herstellung von 16-Methylen-19-norprogesteron-derivaten
CH496663A (de) Verfahren zur Herstellung von 2-Benzyliden-cyclopentanonderivaten
CH461475A (de) Verfahren zur Herstellung von Cycloheptenderivaten
CH507233A (de) Verfahren zur Herstellung von Kalamycinderivaten
CH458370A (de) Verfahren zur Herstellung von Imidazolidinonsulfonamidderivaten
CH494225A (de) Verfahren zur Herstellung von Chinolinderivaten
CH472410A (de) Verfahren zur Herstellung von Hexahydropyrimidinderivaten
CH513879A (de) Verfahren zur Herstellung von Imidazolderivaten
CH534650A (de) Verfahren zur Herstellung von Cyclopropanophenanthren- Derivaten

Legal Events

Date Code Title Description
PL Patent ceased