NZ754901A - Genome engineering - Google Patents

Genome engineering

Info

Publication number
NZ754901A
NZ754901A NZ754901A NZ75490114A NZ754901A NZ 754901 A NZ754901 A NZ 754901A NZ 754901 A NZ754901 A NZ 754901A NZ 75490114 A NZ75490114 A NZ 75490114A NZ 754901 A NZ754901 A NZ 754901A
Authority
NZ
New Zealand
Prior art keywords
stem cell
target dna
present
genome
genome engineering
Prior art date
Application number
NZ754901A
Inventor
George M Church
Luhan Yang
Marc Guell Cargol
Joyce Lichi Yang
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Priority claimed from NZ716606A external-priority patent/NZ716606B2/en
Publication of NZ754901A publication Critical patent/NZ754901A/en

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Abstract

The present invention relates to improved methods of genome engineering in cells using a TALEN lacking repeat sequences or Cas9. More specifically, the present invention provides an isolated stem cell including a first foreign nucleic acid integrated into the genome of the cell and encoding for a Cas9 enzyme that forms a co-localization complex with guide RNA complementary to target DNA and that cleaves the target DNA in a site specific manner, with the proviso that the isolated stem cell excludes a human totipotent stem cell.
NZ754901A 2013-07-26 2014-07-25 Genome engineering NZ754901A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361858866P 2013-07-26 2013-07-26
NZ716606A NZ716606B2 (en) 2013-07-26 2014-07-25 Genome engineering

Publications (1)

Publication Number Publication Date
NZ754901A true NZ754901A (en) 2021-12-24

Family

ID=80053544

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ754901A NZ754901A (en) 2013-07-26 2014-07-25 Genome engineering

Country Status (1)

Country Link
NZ (1) NZ754901A (en)

Also Published As

Publication number Publication date
NZ754902A (en) 2022-03-25
NZ754903A (en) 2021-10-29
NZ754904A (en) 2021-10-29

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Effective date: 20220630

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Effective date: 20230630