NZ749319A - Rna-guided human genome engineering - Google Patents

Rna-guided human genome engineering

Info

Publication number
NZ749319A
NZ749319A NZ749319A NZ74931913A NZ749319A NZ 749319 A NZ749319 A NZ 749319A NZ 749319 A NZ749319 A NZ 749319A NZ 74931913 A NZ74931913 A NZ 74931913A NZ 749319 A NZ749319 A NZ 749319A
Authority
NZ
New Zealand
Prior art keywords
rna
human genome
genome engineering
guide rna
guided human
Prior art date
Application number
NZ749319A
Inventor
George M Church
Prashant Mali
Luhan Yang
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Priority claimed from NZ709429A external-priority patent/NZ709429B2/en
Publication of NZ749319A publication Critical patent/NZ749319A/en

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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention provides a method of altering a stem cell comprising providing to the stem cell a crRNA-tracrRNA fusion guide RNA sequence complementary to a target nucleic acid sequence, and a Cas9 protein which interacts with the guide RNA sequence, wherein the Cas9 protein and the guide RNA sequence form a co-localisation complex with the target nucleic acid sequence.
NZ749319A 2012-12-17 2013-12-16 Rna-guided human genome engineering NZ749319A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261738355P 2012-12-17 2012-12-17
US201361779169P 2013-03-13 2013-03-13
NZ709429A NZ709429B2 (en) 2012-12-17 2013-12-16 Rna-guided human genome engineering

Publications (1)

Publication Number Publication Date
NZ749319A true NZ749319A (en) 2020-06-26

Family

ID=72291340

Family Applications (2)

Application Number Title Priority Date Filing Date
NZ749319A NZ749319A (en) 2012-12-17 2013-12-16 Rna-guided human genome engineering
NZ749305A NZ749305A (en) 2012-12-17 2013-12-16 Rna-guided human genome engineering

Family Applications After (1)

Application Number Title Priority Date Filing Date
NZ749305A NZ749305A (en) 2012-12-17 2013-12-16 Rna-guided human genome engineering

Country Status (1)

Country Link
NZ (2) NZ749319A (en)

Also Published As

Publication number Publication date
NZ749305A (en) 2020-06-26

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