NZ597442A - Hyr1 as a target for active and passive immunization against candida - Google Patents
Hyr1 as a target for active and passive immunization against candidaInfo
- Publication number
- NZ597442A NZ597442A NZ597442A NZ59744210A NZ597442A NZ 597442 A NZ597442 A NZ 597442A NZ 597442 A NZ597442 A NZ 597442A NZ 59744210 A NZ59744210 A NZ 59744210A NZ 597442 A NZ597442 A NZ 597442A
- Authority
- NZ
- New Zealand
- Prior art keywords
- hyr1
- target
- active
- passive immunization
- immunization against
- Prior art date
Links
- 241000222120 Candida <Saccharomycetales> Species 0.000 title 1
- 230000003053 immunization Effects 0.000 title 1
- 238000002649 immunization Methods 0.000 title 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 3
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000004927 fusion Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
- C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
- C07K14/40—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Candida
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0002—Fungal antigens, e.g. Trichophyton, Aspergillus, Candida
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Passenger Equipment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22300509P | 2009-07-03 | 2009-07-03 | |
| PCT/US2010/040949 WO2011003085A1 (en) | 2009-07-03 | 2010-07-02 | Hyr1 as a target for active and passive immunization against candida |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ597442A true NZ597442A (en) | 2014-01-31 |
Family
ID=43411487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ597442A NZ597442A (en) | 2009-07-03 | 2010-07-02 | Hyr1 as a target for active and passive immunization against candida |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US8709446B2 (https=) |
| EP (1) | EP2448959B1 (https=) |
| JP (2) | JP5690822B2 (https=) |
| KR (1) | KR20120085234A (https=) |
| CN (1) | CN102574895B (https=) |
| AU (2) | AU2010266114B2 (https=) |
| BR (1) | BR112012000036A2 (https=) |
| CA (1) | CA2766805A1 (https=) |
| ES (1) | ES2606555T3 (https=) |
| IL (1) | IL217261A0 (https=) |
| MX (1) | MX2012000018A (https=) |
| NZ (1) | NZ597442A (https=) |
| RU (2) | RU2559537C2 (https=) |
| SG (1) | SG177456A1 (https=) |
| WO (1) | WO2011003085A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070077256A1 (en) | 1999-11-19 | 2007-04-05 | Los Angeles Biomedical Research Institute | Pharmaceutical compositions and methods to vaccinate against disseminated candidiasis and other infectious agents |
| WO2011003085A1 (en) | 2009-07-03 | 2011-01-06 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Hyr1 as a target for active and passive immunization against candida |
| GEP201706766B (en) | 2011-07-22 | 2017-10-25 | Los Angeles Biomedical Res Center | Methods and compositions for vaccinating against staphylococcus aureus |
| BR112014005773A2 (pt) * | 2011-09-14 | 2019-09-24 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | composições derivadas de hyr1 e métodos of tratamento usando as mesmas |
| WO2014144024A1 (en) * | 2013-03-15 | 2014-09-18 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Hyr1 compositions and methods for treating fungal and bacterial pathogens |
| US10130691B2 (en) | 2013-03-15 | 2018-11-20 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Compositions and methods for treating fungal and bacterial pathogens |
| GB201306588D0 (en) | 2013-04-11 | 2013-05-29 | King S College London | Peptides and Binding Partners Therefor |
| EP3426287A4 (en) | 2016-03-09 | 2020-03-11 | Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center | Methods and kits for use in preventing and treating vulvovaginal candidiasis |
| CN113508176A (zh) | 2019-02-28 | 2021-10-15 | 米尼翁大学 | 用于控制白色念珠菌感染的反义寡聚物 |
| CN110229221B (zh) * | 2019-06-27 | 2022-04-12 | 上海交通大学医学院附属仁济医院 | 一种用于检测侵袭性白色念珠菌病的抗原及其用途 |
| US20220354935A1 (en) * | 2021-04-21 | 2022-11-10 | Lundquist Institute For Biomedical Innovation At Harbor-Ucla Medical Center | Vaccination against fungal epitopes to prevent inflammatory bowel diseases |
| WO2025248488A1 (en) * | 2024-05-29 | 2025-12-04 | Lundquist Institute For Biomedical Innovation At Harbor-Ucla Medical Center | Compositions and methods for preventing and treating healthcare-associated candida auris infections with dual antigen vaccine |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995031998A1 (en) | 1994-05-23 | 1995-11-30 | The Research & Development Institute, Inc. | Candida albicans adhesin as a vaccine |
| US6747137B1 (en) * | 1998-02-13 | 2004-06-08 | Genome Therapeutics Corporation | Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics |
| US20070077256A1 (en) * | 1999-11-19 | 2007-04-05 | Los Angeles Biomedical Research Institute | Pharmaceutical compositions and methods to vaccinate against disseminated candidiasis and other infectious agents |
| US20060083750A1 (en) * | 1999-11-19 | 2006-04-20 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Pharmaceutical compositions and methods to vaccinate against disseminated candidiasis |
| US6734344B2 (en) * | 1999-12-10 | 2004-05-11 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agrifood | Coniothyrium minitans β-(1,3) exoglucanase gene cbeg 1 |
| US7241613B1 (en) * | 2002-06-05 | 2007-07-10 | Oscient Pharmaceuticals Corporation | Identification of Candida cell surface proteins and their uses |
| RU2316595C1 (ru) * | 2006-06-16 | 2008-02-10 | Институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук | Способ получения антимикробного пептида ареницина |
| WO2011003085A1 (en) | 2009-07-03 | 2011-01-06 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Hyr1 as a target for active and passive immunization against candida |
-
2010
- 2010-07-02 WO PCT/US2010/040949 patent/WO2011003085A1/en not_active Ceased
- 2010-07-02 JP JP2012517920A patent/JP5690822B2/ja active Active
- 2010-07-02 US US13/382,088 patent/US8709446B2/en active Active
- 2010-07-02 CN CN201080039446.5A patent/CN102574895B/zh not_active Expired - Fee Related
- 2010-07-02 ES ES10794828.3T patent/ES2606555T3/es active Active
- 2010-07-02 RU RU2012103502/10A patent/RU2559537C2/ru active IP Right Revival
- 2010-07-02 CA CA2766805A patent/CA2766805A1/en not_active Abandoned
- 2010-07-02 NZ NZ597442A patent/NZ597442A/en not_active IP Right Cessation
- 2010-07-02 SG SG2011097680A patent/SG177456A1/en unknown
- 2010-07-02 KR KR1020127002540A patent/KR20120085234A/ko not_active Withdrawn
- 2010-07-02 RU RU2015122387/10A patent/RU2015122387A/ru not_active Application Discontinuation
- 2010-07-02 EP EP10794828.3A patent/EP2448959B1/en active Active
- 2010-07-02 MX MX2012000018A patent/MX2012000018A/es not_active Application Discontinuation
- 2010-07-02 AU AU2010266114A patent/AU2010266114B2/en not_active Ceased
- 2010-07-02 BR BR112012000036A patent/BR112012000036A2/pt not_active IP Right Cessation
-
2011
- 2011-12-28 IL IL217261A patent/IL217261A0/en unknown
-
2014
- 2014-04-17 US US14/255,072 patent/US20140335114A1/en not_active Abandoned
-
2015
- 2015-02-02 JP JP2015018131A patent/JP2015120722A/ja active Pending
-
2016
- 2016-10-12 AU AU2016244238A patent/AU2016244238A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20120085234A (ko) | 2012-07-31 |
| EP2448959B1 (en) | 2016-09-07 |
| AU2016244238A1 (en) | 2016-10-27 |
| EP2448959A4 (en) | 2013-01-02 |
| AU2010266114B2 (en) | 2016-07-14 |
| RU2012103502A (ru) | 2013-08-10 |
| SG177456A1 (en) | 2012-02-28 |
| RU2015122387A (ru) | 2015-10-27 |
| US8709446B2 (en) | 2014-04-29 |
| MX2012000018A (es) | 2012-03-29 |
| CN102574895B (zh) | 2014-06-11 |
| WO2011003085A1 (en) | 2011-01-06 |
| IL217261A0 (en) | 2012-02-29 |
| JP2015120722A (ja) | 2015-07-02 |
| ES2606555T3 (es) | 2017-03-24 |
| BR112012000036A2 (pt) | 2018-04-03 |
| RU2015122387A3 (https=) | 2019-01-28 |
| RU2559537C2 (ru) | 2015-08-10 |
| WO2011003085A9 (en) | 2011-07-28 |
| CA2766805A1 (en) | 2011-01-06 |
| CN102574895A (zh) | 2012-07-11 |
| JP5690822B2 (ja) | 2015-03-25 |
| JP2012532114A (ja) | 2012-12-13 |
| US20140335114A1 (en) | 2014-11-13 |
| EP2448959A1 (en) | 2012-05-09 |
| AU2010266114A1 (en) | 2012-02-02 |
| US20120237534A1 (en) | 2012-09-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ASS | Change of ownership |
Owner name: LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT H, US Free format text: OLD OWNER(S): LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBORUCLA MEDICAL CENTER; YUE FU; GUANPINGSHENG LUO; ASHRAF IBRAHIM; BRAD J SPELLBERG; JOHN E JR EDWARDS |
|
| S883 | Correction of error according to section 88(3) (mistake in register caused on part of patentee or applicant) |
Free format text: CORRECTION TO TITLE (54) |
|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 02 JUL 2017 BY AJ PARK Effective date: 20140829 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 02 JUL 2018 BY COMPUTER PACKAGES INC Effective date: 20170718 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 02 JUL 2019 BY COMPUTER PACKAGES INC Effective date: 20180619 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 02 JUL 2020 BY COMPUTER PACKAGES INC Effective date: 20190702 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 02 JUL 2021 BY COMPUTER PACKAGES INC Effective date: 20200701 |
|
| LAPS | Patent lapsed |