NZ591108A - Dabigatran for percutaneous interventional cardiac catheterisation - Google Patents
Dabigatran for percutaneous interventional cardiac catheterisationInfo
- Publication number
- NZ591108A NZ591108A NZ591108A NZ59110809A NZ591108A NZ 591108 A NZ591108 A NZ 591108A NZ 591108 A NZ591108 A NZ 591108A NZ 59110809 A NZ59110809 A NZ 59110809A NZ 591108 A NZ591108 A NZ 591108A
- Authority
- NZ
- New Zealand
- Prior art keywords
- dabigatran
- interventional cardiac
- cardiac catheterisation
- percutaneous interventional
- percutaneous
- Prior art date
Links
- 230000000747 cardiac effect Effects 0.000 title abstract 2
- YBSJFWOBGCMAKL-UHFFFAOYSA-N dabigatran Chemical compound N=1C2=CC(C(=O)N(CCC(O)=O)C=3N=CC=CC=3)=CC=C2N(C)C=1CNC1=CC=C(C(N)=N)C=C1 YBSJFWOBGCMAKL-UHFFFAOYSA-N 0.000 title 1
- 229960003850 dabigatran Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 2
- 229960000288 dabigatran etexilate Drugs 0.000 abstract 1
- KSGXQBZTULBEEQ-UHFFFAOYSA-N dabigatran etexilate Chemical compound C1=CC(C(N)=NC(=O)OCCCCCC)=CC=C1NCC1=NC2=CC(C(=O)N(CCC(=O)OCC)C=3N=CC=CC=3)=CC=C2N1C KSGXQBZTULBEEQ-UHFFFAOYSA-N 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9001808P | 2008-08-19 | 2008-08-19 | |
| PCT/EP2009/060592 WO2010020602A1 (en) | 2008-08-19 | 2009-08-17 | Dabigatran for percutaneous interventional cardiac catheterisation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ591108A true NZ591108A (en) | 2012-11-30 |
Family
ID=41258283
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ591108A NZ591108A (en) | 2008-08-19 | 2009-08-17 | Dabigatran for percutaneous interventional cardiac catheterisation |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20110301201A1 (enExample) |
| EP (1) | EP2328580A1 (enExample) |
| JP (1) | JP2012500245A (enExample) |
| KR (1) | KR20110044230A (enExample) |
| CN (1) | CN102123707A (enExample) |
| AR (1) | AR073077A1 (enExample) |
| AU (1) | AU2009284217A1 (enExample) |
| BR (1) | BRPI0917507A2 (enExample) |
| CA (1) | CA2734794A1 (enExample) |
| CL (1) | CL2011000361A1 (enExample) |
| CO (1) | CO6290686A2 (enExample) |
| EA (1) | EA201100358A1 (enExample) |
| EC (1) | ECSP11010825A (enExample) |
| IL (1) | IL210005A0 (enExample) |
| MA (1) | MA32563B1 (enExample) |
| MX (1) | MX2011001612A (enExample) |
| NZ (1) | NZ591108A (enExample) |
| TW (1) | TW201022235A (enExample) |
| WO (1) | WO2010020602A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102209544A (zh) | 2008-11-11 | 2011-10-05 | 贝林格尔.英格海姆国际有限公司 | 使用达比加群酯或其盐治疗或预防血栓形成且与常规的华法林疗法相比具有改良安全性的方法 |
| CA2791561A1 (en) * | 2010-03-01 | 2011-09-09 | Ratiopharm Gmbh | Dabigatran etexilate-containing oral pharmaceutical composition |
| JP6155187B2 (ja) | 2010-03-30 | 2017-06-28 | ヴァーセオン コーポレイション | トロンビンの阻害剤としての多置換芳香族化合物 |
| CN102391250B (zh) * | 2011-08-29 | 2013-06-19 | 石药集团欧意药业有限公司 | 一种达比加群酯化合物、制备方法及其药物组合物 |
| CN102558153A (zh) * | 2012-02-08 | 2012-07-11 | 北京阜康仁生物制药科技有限公司 | 达比加群酯的新药用盐及其制备方法 |
| CN103420982B (zh) * | 2012-05-24 | 2015-07-08 | 天津药物研究院 | 达比加群酯衍生物及其制备方法和用途 |
| CN103420994B (zh) * | 2012-05-24 | 2016-04-06 | 天津药物研究院 | 作为前药的达比加群酯衍生物及其制备方法和用途 |
| CN103420985B (zh) * | 2012-05-24 | 2015-09-23 | 天津药物研究院 | 作为前药的达比加群酯衍生物及其制备方法和用途 |
| CN103420984B (zh) * | 2012-05-24 | 2015-07-08 | 天津药物研究院 | 作为前药的达比加群酯衍生物及其制备方法和用途 |
| CN103524559B (zh) * | 2012-07-05 | 2016-09-28 | 西藏海思科药业集团股份有限公司 | 多取代4-甲氨基苯甲脒的酯衍生物及其制备方法和用途 |
| CN103539779B (zh) * | 2012-07-13 | 2016-12-21 | 四川海思科制药有限公司 | 一种达比加群酯的羟基取代苯磺酸盐及其制备方法和用途 |
| US20150225370A1 (en) * | 2012-09-28 | 2015-08-13 | Ranbaxy Laboratories Limited | Process for the preparation of dabigatran etexilate or pharmaceutically acceptable salt thereof |
| US9399616B2 (en) * | 2012-10-22 | 2016-07-26 | Boehringer Ingelheim International Gmbh | Process for the manufacture of 4-aminobenzoamidine dihydrochloride |
| WO2014145986A1 (en) | 2013-03-15 | 2014-09-18 | Verseon, Inc. | Multisubstituted aromatic compounds as serine protease inhibitors |
| ES2791749T3 (es) | 2013-03-15 | 2020-11-05 | Verseon Corp | Halogenopirazoles como inhibidores de la trombina |
| KR20170048410A (ko) | 2014-09-17 | 2017-05-08 | 베르선 코포레이션 | 세린 프로테아제 저해제로서의 피라졸릴-치환된 피리돈 화합물 |
| AU2016224974B2 (en) | 2015-02-27 | 2019-09-26 | Verseon Corporation | Substituted pyrazole compounds as serine protease inhibitors |
| IL280078B2 (en) | 2018-07-13 | 2024-04-01 | Verseon Int Corporation | Thrombin inhibitors, formulations, and uses thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1870100T1 (sl) * | 2002-03-07 | 2012-05-31 | Boehringer Ingelheim Int | Metansulfonat etil estra heksiloksikarbonilamino imino metil fenilamino metil metil H benzimidazol karbonil piridin il amino propionske kisline |
| CA2587026A1 (en) * | 2004-10-25 | 2006-05-04 | Boehringer Ingelheim International Gmbh | Use of dipyridamole in combination with antithrombotics for treatment and prevention of thromboembolic diseases |
| AR061996A1 (es) * | 2006-07-17 | 2008-08-10 | Boehringer Ingelheim Int | Indicaciones para los inhibidores directos de la trombina en el campo cardiovascular |
| JP2009543844A (ja) * | 2006-07-17 | 2009-12-10 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 直接トロンビン阻害剤の新しい小児適応症 |
| EP2074112A1 (en) * | 2006-10-10 | 2009-07-01 | Boehringer Ingelheim International GmbH | Physiologically acceptable salts of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1h-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester |
-
2009
- 2009-08-17 EA EA201100358A patent/EA201100358A1/ru unknown
- 2009-08-17 EP EP09781886A patent/EP2328580A1/en not_active Withdrawn
- 2009-08-17 AU AU2009284217A patent/AU2009284217A1/en not_active Abandoned
- 2009-08-17 KR KR1020117003645A patent/KR20110044230A/ko not_active Withdrawn
- 2009-08-17 JP JP2011523405A patent/JP2012500245A/ja active Pending
- 2009-08-17 WO PCT/EP2009/060592 patent/WO2010020602A1/en not_active Ceased
- 2009-08-17 BR BRPI0917507A patent/BRPI0917507A2/pt not_active IP Right Cessation
- 2009-08-17 NZ NZ591108A patent/NZ591108A/xx not_active IP Right Cessation
- 2009-08-17 CN CN2009801318235A patent/CN102123707A/zh active Pending
- 2009-08-17 CA CA2734794A patent/CA2734794A1/en not_active Abandoned
- 2009-08-17 MX MX2011001612A patent/MX2011001612A/es not_active Application Discontinuation
- 2009-08-17 US US13/058,920 patent/US20110301201A1/en not_active Abandoned
- 2009-08-18 AR ARP090103168A patent/AR073077A1/es unknown
- 2009-08-18 TW TW098127736A patent/TW201022235A/zh unknown
-
2010
- 2010-12-15 IL IL210005A patent/IL210005A0/en unknown
-
2011
- 2011-02-11 EC EC2011010825A patent/ECSP11010825A/es unknown
- 2011-02-15 MA MA33616A patent/MA32563B1/fr unknown
- 2011-02-17 CO CO11018905A patent/CO6290686A2/es not_active Application Discontinuation
- 2011-02-18 CL CL2011000361A patent/CL2011000361A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2328580A1 (en) | 2011-06-08 |
| CO6290686A2 (es) | 2011-06-20 |
| WO2010020602A1 (en) | 2010-02-25 |
| KR20110044230A (ko) | 2011-04-28 |
| MX2011001612A (es) | 2011-03-04 |
| BRPI0917507A2 (pt) | 2015-11-17 |
| CL2011000361A1 (es) | 2011-06-17 |
| MA32563B1 (fr) | 2011-08-01 |
| CA2734794A1 (en) | 2010-02-25 |
| JP2012500245A (ja) | 2012-01-05 |
| TW201022235A (en) | 2010-06-16 |
| CN102123707A (zh) | 2011-07-13 |
| EA201100358A1 (ru) | 2011-10-31 |
| ECSP11010825A (es) | 2011-03-31 |
| IL210005A0 (en) | 2011-02-28 |
| AR073077A1 (es) | 2010-10-13 |
| AU2009284217A1 (en) | 2010-02-25 |
| US20110301201A1 (en) | 2011-12-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| LAPS | Patent lapsed |