NZ590833A - Genetic variants for breast cancer risk assessment - Google Patents
Genetic variants for breast cancer risk assessmentInfo
- Publication number
- NZ590833A NZ590833A NZ590833A NZ59083309A NZ590833A NZ 590833 A NZ590833 A NZ 590833A NZ 590833 A NZ590833 A NZ 590833A NZ 59083309 A NZ59083309 A NZ 59083309A NZ 590833 A NZ590833 A NZ 590833A
- Authority
- NZ
- New Zealand
- Prior art keywords
- breast cancer
- individual
- marker
- linkage disequilibrium
- markers
- Prior art date
Links
- 206010006187 Breast cancer Diseases 0.000 title abstract 5
- 208000026310 Breast neoplasm Diseases 0.000 title abstract 5
- 230000002068 genetic effect Effects 0.000 title abstract 3
- 238000012502 risk assessment Methods 0.000 title 1
- 239000003550 marker Substances 0.000 abstract 6
- 102000054766 genetic haplotypes Human genes 0.000 abstract 3
- 108700028369 Alleles Proteins 0.000 abstract 2
- 238000004590 computer program Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B99/00—Subject matter not provided for in other groups of this subclass
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
- G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
- G16C20/60—In silico combinatorial chemistry
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Theoretical Computer Science (AREA)
- Evolutionary Biology (AREA)
- Medical Informatics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Library & Information Science (AREA)
- Medicinal Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Computing Systems (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IS8746 | 2008-07-07 | ||
| PCT/IS2009/000008 WO2010004591A2 (en) | 2008-07-07 | 2009-07-03 | Genetic variants for breast cancer risk assessment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ590833A true NZ590833A (en) | 2013-01-25 |
Family
ID=41110719
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ590833A NZ590833A (en) | 2008-07-07 | 2009-07-03 | Genetic variants for breast cancer risk assessment |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8951735B2 (https=) |
| EP (1) | EP2313525A2 (https=) |
| JP (1) | JP2011527565A (https=) |
| KR (1) | KR20110036608A (https=) |
| CN (1) | CN102144036B (https=) |
| AU (1) | AU2009269542A1 (https=) |
| CA (1) | CA2729934A1 (https=) |
| IL (1) | IL210504A0 (https=) |
| NZ (1) | NZ590833A (https=) |
| WO (1) | WO2010004591A2 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011095999A1 (en) * | 2010-02-05 | 2011-08-11 | Decode Genetics Ehf | Genetic variants for predicting risk of breast cancer |
| HK1197085A1 (en) * | 2011-06-16 | 2015-01-02 | Decode Genetics Ehf | Genetic variants for predicting risk of breast cancer |
| CN102643905B (zh) * | 2012-04-01 | 2014-06-11 | 周宏灏 | 焦磷酸测序法检测他莫昔芬个体化用药基因多态性的试剂盒及方法 |
| WO2014119914A1 (ko) * | 2013-02-01 | 2014-08-07 | 에스케이텔레콤 주식회사 | 유전자 서열 기반 개인 마커에 관한 정보를 제공하는 방법 및 이를 이용한 장치 |
| KR101770962B1 (ko) * | 2013-02-01 | 2017-08-24 | 에스케이텔레콤 주식회사 | 유전자 서열 기반 개인 마커에 관한 정보를 제공하는 방법 및 이를 이용한 장치 |
| WO2014145705A2 (en) | 2013-03-15 | 2014-09-18 | Battelle Memorial Institute | Progression analytics system |
| CN103981273B (zh) * | 2014-05-30 | 2017-01-18 | 复旦大学附属肿瘤医院 | 一组评估乳腺癌风险的突变基因群及其检测试剂盒 |
| US10395759B2 (en) | 2015-05-18 | 2019-08-27 | Regeneron Pharmaceuticals, Inc. | Methods and systems for copy number variant detection |
| CN105069322B (zh) * | 2015-07-24 | 2018-01-12 | 上海尔云信息科技有限公司 | 疾病易感风险预测装置 |
| CA3014292A1 (en) | 2016-02-12 | 2017-08-17 | Regeneron Pharmaceuticals, Inc. | Methods and systems for detection of abnormal karyotypes |
| CN105586427B (zh) * | 2016-03-10 | 2020-06-19 | 厦门艾德生物医药科技股份有限公司 | 检测人类brca1和brca2基因突变的引物、试剂盒及方法 |
| US11332530B2 (en) | 2016-09-23 | 2022-05-17 | Memorial Sloan Kettering Cancer Center | Determinants of cancer response to immunotherapy |
| CN106676169B (zh) * | 2016-11-15 | 2021-01-12 | 上海派森诺医学检验所有限公司 | 一种用于乳腺癌易感基因brca1和brca2突变检测的杂交捕获试剂盒及其方法 |
| JP2020508643A (ja) * | 2017-01-24 | 2020-03-26 | ジェネティック テクノロジーズ リミテッド | 乳癌発症リスクの改良された評価法 |
| CN107341347A (zh) * | 2017-06-27 | 2017-11-10 | 天方创新（北京）信息技术有限公司 | 基于评分模型对乳腺癌进行风险评分的方法及装置 |
| CN112534070B (zh) * | 2018-06-29 | 2024-07-30 | 杰克逊实验室 | 乳腺癌剪接变体 |
| CN108676890B (zh) * | 2018-07-12 | 2022-01-28 | 吉林大学 | 一种女性乳腺恶性肿瘤易感性预测试剂盒及系统 |
| US20230170045A1 (en) * | 2020-04-20 | 2023-06-01 | Myriad Genetics, Inc. | Comprehensive polygenic risk prediction for breast cancer |
| WO2024085660A1 (ko) * | 2022-10-18 | 2024-04-25 | 제노플랜 인크 | 질병 발생 위험도 예측 장치 및 방법 |
| EP4646208A1 (en) | 2023-01-06 | 2025-11-12 | Ideaya Biosciences, Inc. | Treatment of er+ breast cancer comprising homologous recombination deficiency using parg inhibitor |
| CN119446277B (zh) * | 2024-10-31 | 2026-03-27 | 中国人民解放军总医院 | 分子检测方法、装置、计算机设备、存储介质和程序产品 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| GB8810400D0 (en) | 1988-05-03 | 1988-06-08 | Southern E | Analysing polynucleotide sequences |
| US5700637A (en) | 1988-05-03 | 1997-12-23 | Isis Innovation Limited | Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays |
| US6054270A (en) | 1988-05-03 | 2000-04-25 | Oxford Gene Technology Limited | Analying polynucleotide sequences |
| EP0436597B1 (en) | 1988-09-02 | 1997-04-02 | Protein Engineering Corporation | Generation and selection of recombinant varied binding proteins |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| US5288644A (en) | 1990-04-04 | 1994-02-22 | The Rockefeller University | Instrument and method for the sequencing of genome |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| EP0585287B1 (en) | 1990-07-10 | 1999-10-13 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| CA2405246A1 (en) | 1990-12-03 | 1992-06-11 | Genentech, Inc. | Enrichment method for variant proteins with alterred binding properties |
| EP0575485A1 (en) | 1991-03-01 | 1993-12-29 | Dyax Corp. | Process for the development of binding mini-proteins |
| DK0580737T3 (da) | 1991-04-10 | 2004-11-01 | Scripps Research Inst | Heterodimere receptorbiblioteker ved anvendelse af phagemider |
| DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
| US6287850B1 (en) | 1995-06-07 | 2001-09-11 | Affymetrix, Inc. | Bioarray chip reaction apparatus and its manufacture |
| EP0695941B1 (en) | 1994-06-08 | 2002-07-31 | Affymetrix, Inc. | Method and apparatus for packaging a chip |
| US6300063B1 (en) | 1995-11-29 | 2001-10-09 | Affymetrix, Inc. | Polymorphism detection |
| EP1736554B1 (en) | 1996-05-29 | 2013-10-09 | Cornell Research Foundation, Inc. | Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions |
| US6429027B1 (en) | 1998-12-28 | 2002-08-06 | Illumina, Inc. | Composite arrays utilizing microspheres |
| US20040009481A1 (en) * | 2001-06-11 | 2004-01-15 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of human prostate cancer |
| DE10228081A1 (de) * | 2002-06-18 | 2004-01-08 | InViTek Gesellschaft für Biotechnik & Biodesign mbH | Verfahren zum Nachweis einer gesteigerten Tumorsuszeptibilität |
| KR100763902B1 (ko) * | 2004-02-20 | 2007-10-05 | 삼성전자주식회사 | 유방암 특이적 단백질, 그를 코딩하는 유전자, 및 상기단백질 또는 유전자를 이용한 유방암의 진단 방법 |
| WO2006063285A2 (en) * | 2004-12-10 | 2006-06-15 | Sequenom, Inc. | Methods for identifying risk of breast cancer or prostate cancer and treatments thereof |
| CN101037690B (zh) * | 2006-03-16 | 2011-07-20 | 国家人口计生委科学技术研究所 | 具有新的单核苷酸多态性的brca1基因变体和其编码的蛋白质变体 |
| JP5631000B2 (ja) * | 2006-10-27 | 2014-11-26 | デコード・ジェネティクス・イーエイチエフ | Ｃｈｒ８ｑ２４．２１上の癌感受性変異体 |
| EA019953B1 (ru) | 2007-03-26 | 2014-07-30 | Декоуд Дженетикс Ехф | Генетические варианты chr2 и chr16 в качестве маркеров для применения при оценке риска, диагностировании, прогнозировании и лечении рака молочной железы |
| CA2688312A1 (en) | 2007-05-25 | 2008-12-04 | Decode Genetics Ehf. | Genetic variants on chr 5p12 and 10q26 as markers for use in breast cancer risk assessment, diagnosis, prognosis and treatment |
-
2009
- 2009-07-03 JP JP2011517318A patent/JP2011527565A/ja active Pending
- 2009-07-03 WO PCT/IS2009/000008 patent/WO2010004591A2/en not_active Ceased
- 2009-07-03 CA CA2729934A patent/CA2729934A1/en not_active Abandoned
- 2009-07-03 CN CN200980134453.0A patent/CN102144036B/zh not_active Expired - Fee Related
- 2009-07-03 NZ NZ590833A patent/NZ590833A/xx not_active IP Right Cessation
- 2009-07-03 US US13/002,619 patent/US8951735B2/en not_active Expired - Fee Related
- 2009-07-03 EP EP09787620A patent/EP2313525A2/en not_active Withdrawn
- 2009-07-03 AU AU2009269542A patent/AU2009269542A1/en not_active Abandoned
- 2009-07-03 KR KR1020117002889A patent/KR20110036608A/ko not_active Ceased
-
2011
- 2011-01-06 IL IL210504A patent/IL210504A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN102144036B (zh) | 2014-07-16 |
| CA2729934A1 (en) | 2010-01-14 |
| US8951735B2 (en) | 2015-02-10 |
| AU2009269542A1 (en) | 2010-01-14 |
| IL210504A0 (en) | 2011-03-31 |
| WO2010004591A3 (en) | 2010-03-18 |
| US20110294673A1 (en) | 2011-12-01 |
| WO2010004591A2 (en) | 2010-01-14 |
| KR20110036608A (ko) | 2011-04-07 |
| EP2313525A2 (en) | 2011-04-27 |
| CN102144036A (zh) | 2011-08-03 |
| JP2011527565A (ja) | 2011-11-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NZ590833A (en) | Genetic variants for breast cancer risk assessment | |
| NZ580490A (en) | Genetic variaints on CHR2 and CHR16 in linkage disequilibrium with rs 13387042 as markers for use in breast cancer assesment | |
| NZ590893A (en) | Genetic variants as markers for use in urinary bladder cancer risk assessment, diagnosis, prognosis and treatment | |
| NZ593628A (en) | Genetic variants useful for risk assessment of thyroid cancer using rs944289 | |
| JP2011530306A5 (https=) | ||
| Chen et al. | Disentangling the roles of history and local selection in shaping clinal variation of allele frequencies and gene expression in Norway spruce (Picea abies) | |
| NZ590832A (en) | Genetic variants for schizophrenia risk assessment | |
| NZ598009A (en) | Genetic markers associated with risk of diabetes mellitus | |
| JP2010522555A5 (https=) | ||
| JP2010507388A5 (https=) | ||
| NZ587903A (en) | Susceptibility for lung cancer using the polymorphic marker rs1051730 | |
| JP2010520745A5 (https=) | ||
| NZ596070A (en) | Genetic variants contributing to risk of prostate cancer | |
| JP2011527565A5 (https=) | ||
| CN110358840B (zh) | 与剩余采食量相关的tpp2基因的snp分子遗传标记 | |
| NZ591711A (en) | A method for predicting athletic performance potential | |
| Karimi et al. | Comparison of linkage disequilibrium levels in Iranian indigenous cattle using whole genome SNPs data | |
| CN103045739A (zh) | 一种拟穴青蟹SNPs分子标记的筛选方法 | |
| CN101892312A (zh) | 一种鸡肉品质分子育种方法 | |
| Roca-Umbert et al. | Human genetic adaptation related to cellular zinc homeostasis | |
| CN110358839B (zh) | 与猪饲料转化率相关的gckr基因的snp分子遗传标记 | |
| CN110295236A (zh) | 猪饲料转化率的snp分子遗传标记 | |
| CN115948569A (zh) | 位于mc4r-ccbe1基因座的分子标记及其在猪背膘厚性状遗传改良中的应用 | |
| NZ586431A (en) | Genetic variants on chr hq and 6q as markers for prostate and colorectal cancer predisposition | |
| CN102220410A (zh) | 一种辅助鉴定具有不同体重性状鸡的方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 03 JUL 2016 BY LEA SKYLLERSTEDT Effective date: 20130802 |
|
| LAPS | Patent lapsed |