NZ584269A - Inhaled aztreonam lysine for the treatment of deficits in health-related quality-of life in lung diseases - Google Patents
Inhaled aztreonam lysine for the treatment of deficits in health-related quality-of life in lung diseasesInfo
- Publication number
- NZ584269A NZ584269A NZ584269A NZ58426908A NZ584269A NZ 584269 A NZ584269 A NZ 584269A NZ 584269 A NZ584269 A NZ 584269A NZ 58426908 A NZ58426908 A NZ 58426908A NZ 584269 A NZ584269 A NZ 584269A
- Authority
- NZ
- New Zealand
- Prior art keywords
- domain
- day
- azli
- dose
- aerosol
- Prior art date
Links
- KPPBAEVZLDHCOK-JHBYREIPSA-N (2s,3s)-3-[[(2z)-2-(2-azaniumyl-1,3-thiazol-4-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-2-methyl-4-oxoazetidine-1-sulfonate;(2s)-2,6-diaminohexanoic acid Chemical compound NCCCC[C@H](N)C(O)=O.O=C1N(S([O-])(=O)=O)[C@@H](C)[C@@H]1NC(=O)C(=N/OC(C)(C)C(O)=O)\C1=CSC([NH3+])=N1 KPPBAEVZLDHCOK-JHBYREIPSA-N 0.000 title claims abstract description 107
- 229950010471 aztreonam lysine Drugs 0.000 title claims abstract description 106
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- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 269
- 239000011780 sodium chloride Substances 0.000 claims description 151
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- 229960003644 aztreonam Drugs 0.000 claims description 99
- WZPBZJONDBGPKJ-VEHQQRBSSA-N aztreonam Chemical compound O=C1N(S([O-])(=O)=O)[C@@H](C)[C@@H]1NC(=O)C(=N/OC(C)(C)C(O)=O)\C1=CSC([NH3+])=N1 WZPBZJONDBGPKJ-VEHQQRBSSA-N 0.000 claims description 97
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99707207P | 2007-10-01 | 2007-10-01 | |
| US99707107P | 2007-10-01 | 2007-10-01 | |
| PCT/US2008/076431 WO2009045706A1 (en) | 2007-10-01 | 2008-09-15 | Inhaled aztreonam lysine for the treatment of deficits in health-related quality-of life in lung diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ584269A true NZ584269A (en) | 2012-06-29 |
Family
ID=40032482
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ584269A NZ584269A (en) | 2007-10-01 | 2008-09-15 | Inhaled aztreonam lysine for the treatment of deficits in health-related quality-of life in lung diseases |
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| EP (1) | EP2200608A1 (enExample) |
| JP (1) | JP2010540539A (enExample) |
| KR (1) | KR20100093037A (enExample) |
| CN (1) | CN101951906A (enExample) |
| AR (1) | AR068514A1 (enExample) |
| AU (1) | AU2008307268A1 (enExample) |
| BR (1) | BRPI0817636A2 (enExample) |
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| EA (1) | EA201070336A1 (enExample) |
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| NZ (1) | NZ584269A (enExample) |
| TW (1) | TW200927193A (enExample) |
| WO (1) | WO2009045706A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7214364B2 (en) | 2000-12-27 | 2007-05-08 | Corus Pharma, Inc. | Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections |
| DK2301524T3 (da) | 2000-12-27 | 2013-07-15 | Gilead Sciences Inc | Inhalerbar aztreonam uden arginin til behandling og forebyggelse af bakterielle lungeinfektioner |
| CN104784159A (zh) * | 2015-04-15 | 2015-07-22 | 苏州惠仁生物科技有限公司 | 氨曲南粉雾剂的制备方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5152456A (en) | 1989-12-12 | 1992-10-06 | Bespak, Plc | Dispensing apparatus having a perforate outlet member and a vibrating device |
| EP0615470B1 (en) | 1991-12-04 | 1995-12-13 | The Technology Partnership Public Limited Company | Fluid droplet production apparatus and method |
| DE19953317C1 (de) | 1999-11-05 | 2001-02-01 | Pari Gmbh | Inhalationsvernebler |
| US6962151B1 (en) | 1999-11-05 | 2005-11-08 | Pari GmbH Spezialisten für effektive Inhalation | Inhalation nebulizer |
| US7214364B2 (en) | 2000-12-27 | 2007-05-08 | Corus Pharma, Inc. | Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections |
| US7138419B2 (en) * | 2000-12-27 | 2006-11-21 | Corus Pharma, Inc. | Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate |
| DK2301524T3 (da) | 2000-12-27 | 2013-07-15 | Gilead Sciences Inc | Inhalerbar aztreonam uden arginin til behandling og forebyggelse af bakterielle lungeinfektioner |
| DE10102846B4 (de) | 2001-01-23 | 2012-04-12 | Pari Pharma Gmbh | Aerosolgenerator |
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2008
- 2008-09-15 WO PCT/US2008/076431 patent/WO2009045706A1/en not_active Ceased
- 2008-09-15 KR KR1020107009839A patent/KR20100093037A/ko not_active Withdrawn
- 2008-09-15 NZ NZ584269A patent/NZ584269A/en not_active IP Right Cessation
- 2008-09-15 MX MX2010003618A patent/MX2010003618A/es not_active Application Discontinuation
- 2008-09-15 BR BRPI0817636A patent/BRPI0817636A2/pt not_active IP Right Cessation
- 2008-09-15 AU AU2008307268A patent/AU2008307268A1/en not_active Abandoned
- 2008-09-15 JP JP2010527021A patent/JP2010540539A/ja active Pending
- 2008-09-15 EP EP08836327A patent/EP2200608A1/en not_active Withdrawn
- 2008-09-15 CN CN2008801170106A patent/CN101951906A/zh active Pending
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- 2008-09-15 EA EA201070336A patent/EA201070336A1/ru unknown
- 2008-09-15 TW TW097135359A patent/TW200927193A/zh unknown
- 2008-09-15 CA CA2701118A patent/CA2701118A1/en not_active Abandoned
- 2008-09-15 AR ARP080104006A patent/AR068514A1/es not_active Application Discontinuation
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2010
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Also Published As
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| BRPI0817636A2 (pt) | 2019-09-24 |
| IL204593A0 (en) | 2010-11-30 |
| MX2010003618A (es) | 2010-04-21 |
| US7973029B2 (en) | 2011-07-05 |
| AR068514A1 (es) | 2009-11-18 |
| CN101951906A (zh) | 2011-01-19 |
| TW200927193A (en) | 2009-07-01 |
| JP2010540539A (ja) | 2010-12-24 |
| EP2200608A1 (en) | 2010-06-30 |
| CA2701118A1 (en) | 2009-04-09 |
| EA201070336A1 (ru) | 2011-06-30 |
| KR20100093037A (ko) | 2010-08-24 |
| US20090124594A1 (en) | 2009-05-14 |
| WO2009045706A1 (en) | 2009-04-09 |
| AU2008307268A1 (en) | 2009-04-09 |
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