NZ574216A - Treatment of cartilage disorders with fgf-18 - Google Patents
Treatment of cartilage disorders with fgf-18Info
- Publication number
- NZ574216A NZ574216A NZ574216A NZ57421607A NZ574216A NZ 574216 A NZ574216 A NZ 574216A NZ 574216 A NZ574216 A NZ 574216A NZ 57421607 A NZ57421607 A NZ 57421607A NZ 574216 A NZ574216 A NZ 574216A
- Authority
- NZ
- New Zealand
- Prior art keywords
- lys
- arg
- leu
- thr
- val
- Prior art date
Links
- 102000003977 fibroblast growth factor 18 Human genes 0.000 title claims abstract description 177
- 108090000370 fibroblast growth factor 18 Proteins 0.000 title claims abstract description 177
- 238000011282 treatment Methods 0.000 title claims abstract description 99
- 208000015100 cartilage disease Diseases 0.000 title claims abstract description 52
- 150000001875 compounds Chemical class 0.000 claims abstract description 60
- 206010061762 Chondropathy Diseases 0.000 claims abstract description 41
- 239000003814 drug Substances 0.000 claims abstract description 25
- 238000004519 manufacturing process Methods 0.000 claims abstract description 15
- 201000008482 osteoarthritis Diseases 0.000 claims description 58
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- 238000001990 intravenous administration Methods 0.000 claims description 11
- 241000282414 Homo sapiens Species 0.000 claims description 10
- 108010068380 arginylarginine Proteins 0.000 claims description 10
- 108010047857 aspartylglycine Proteins 0.000 claims description 10
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06119557 | 2006-08-25 | ||
| US84060006P | 2006-08-28 | 2006-08-28 | |
| PCT/EP2007/058830 WO2008023063A2 (en) | 2006-08-25 | 2007-08-24 | Treatment of cartilage disorders with fgf-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ574216A true NZ574216A (en) | 2011-11-25 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ574216A NZ574216A (en) | 2006-08-25 | 2007-08-24 | Treatment of cartilage disorders with fgf-18 |
Country Status (11)
| Country | Link |
|---|---|
| CN (1) | CN101505787B (da) |
| BR (1) | BRPI0715728A8 (da) |
| DK (1) | DK2054050T3 (da) |
| ES (1) | ES2392883T3 (da) |
| MY (1) | MY148277A (da) |
| NZ (1) | NZ574216A (da) |
| PT (1) | PT2054050E (da) |
| RS (1) | RS52710B (da) |
| SI (1) | SI2054050T1 (da) |
| UA (1) | UA99818C2 (da) |
| ZA (1) | ZA200900426B (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2880179B1 (en) * | 2012-08-06 | 2017-12-13 | Merck Patent GmbH | Genetic markers for predicting responsiveness to fgf-18 compound |
| EP3107591B1 (en) * | 2014-02-20 | 2018-04-18 | Merck Patent GmbH | Fgf-18 in graft transplantation and tissue engineering procedures |
| PL3107592T3 (pl) * | 2014-02-20 | 2019-02-28 | Merck Patent Gmbh | Implant zawierający FGF-18 |
| MX2016010872A (es) * | 2014-02-20 | 2016-11-17 | Merck Patent Gmbh | Regimen de dosificacion del compuesto de factor de crecimiento de fibroblastos 18. |
| WO2016112176A1 (en) * | 2015-01-08 | 2016-07-14 | University Of Iowa Research Foundation | Methods for the regeneration of articular cartilage in vivo |
| EP3957654A1 (en) * | 2015-07-15 | 2022-02-23 | Prosit Sole Biotechnology (Beijing) Co., Ltd | Fusion polypeptides and methods of use |
| US20180236032A1 (en) * | 2015-08-13 | 2018-08-23 | Merck Patent Gmbh | Combination composition comprising fgf-18 compound |
| CA3162235A1 (en) * | 2019-11-21 | 2021-05-27 | Remedium Bio, Inc. | Growth factor restoration |
| US11904006B2 (en) | 2019-12-11 | 2024-02-20 | University Of Iowa Research Foundation | Poly(diaminosulfide) particle-based vaccine |
| CN117721115A (zh) * | 2022-09-06 | 2024-03-19 | 深圳瑞吉生物科技有限公司 | 用于治疗骨关节炎的mRNA及其制备方法与应用 |
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| ES2493840T3 (es) * | 2002-10-07 | 2014-09-12 | Zymogenetics, Inc. | Procedimiento de administración de FGF-18 |
| EP1896053B1 (en) * | 2004-07-06 | 2018-10-31 | ZymoGenetics, Inc. | Pharmaceutical composition comprising fgf18 and il-1 antagonist and method of use |
| US7858341B2 (en) * | 2004-12-10 | 2010-12-28 | Zymogenetics, Inc. | FGF18 production in prokaryotic hosts |
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2007
- 2007-08-24 RS RS20120483A patent/RS52710B/en unknown
- 2007-08-24 SI SI200731047T patent/SI2054050T1/sl unknown
- 2007-08-24 BR BRPI0715728A patent/BRPI0715728A8/pt not_active Application Discontinuation
- 2007-08-24 PT PT07802876T patent/PT2054050E/pt unknown
- 2007-08-24 ES ES07802876T patent/ES2392883T3/es active Active
- 2007-08-24 MY MYPI20090702A patent/MY148277A/en unknown
- 2007-08-24 ZA ZA200900426A patent/ZA200900426B/xx unknown
- 2007-08-24 DK DK07802876.8T patent/DK2054050T3/da active
- 2007-08-24 NZ NZ574216A patent/NZ574216A/en unknown
- 2007-08-24 CN CN2007800312016A patent/CN101505787B/zh active Active
- 2007-08-24 UA UAA200902217A patent/UA99818C2/ru unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0715728A8 (pt) | 2018-04-03 |
| BRPI0715728A2 (pt) | 2013-09-17 |
| CN101505787A (zh) | 2009-08-12 |
| DK2054050T3 (da) | 2012-09-03 |
| PT2054050E (pt) | 2012-09-17 |
| RS52710B (en) | 2013-08-30 |
| MY148277A (en) | 2013-03-29 |
| UA99818C2 (ru) | 2012-10-10 |
| ES2392883T3 (es) | 2012-12-14 |
| SI2054050T1 (sl) | 2012-12-31 |
| ZA200900426B (en) | 2010-04-28 |
| CN101505787B (zh) | 2013-09-04 |
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