NZ572308A - Compositions of less immunogenic and long-circulating protein-lipid complexes - Google Patents
Compositions of less immunogenic and long-circulating protein-lipid complexesInfo
- Publication number
- NZ572308A NZ572308A NZ572308A NZ57230807A NZ572308A NZ 572308 A NZ572308 A NZ 572308A NZ 572308 A NZ572308 A NZ 572308A NZ 57230807 A NZ57230807 A NZ 57230807A NZ 572308 A NZ572308 A NZ 572308A
- Authority
- NZ
- New Zealand
- Prior art keywords
- particles
- protein
- factor
- lipidic
- cholesterol
- Prior art date
Links
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- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 claims abstract description 24
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Classifications
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
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- A—HUMAN NECESSITIES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/37—Factors VIII
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
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- A—HUMAN NECESSITIES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Dispersion Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78741106P | 2006-03-30 | 2006-03-30 | |
| US78758606P | 2006-03-30 | 2006-03-30 | |
| US86506206P | 2006-11-09 | 2006-11-09 | |
| US87017706P | 2006-12-15 | 2006-12-15 | |
| PCT/US2007/008311 WO2007117469A2 (en) | 2006-03-30 | 2007-03-30 | Compositions of less immunogenic and long-circulating protein-lipid complexes |
Publications (1)
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| NZ572308A true NZ572308A (en) | 2011-09-30 |
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| NZ572308A NZ572308A (en) | 2006-03-30 | 2007-03-30 | Compositions of less immunogenic and long-circulating protein-lipid complexes |
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|---|---|
| US (2) | US7875289B2 (https=) |
| EP (1) | EP2007357B1 (https=) |
| JP (1) | JP5160534B2 (https=) |
| AU (1) | AU2007235463B2 (https=) |
| CA (1) | CA2660310C (https=) |
| NZ (1) | NZ572308A (https=) |
| WO (1) | WO2007117469A2 (https=) |
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| WO2007117469A2 (en) * | 2006-03-30 | 2007-10-18 | The Research Foundation Of State University Of New York | Compositions of less immunogenic and long-circulating protein-lipid complexes |
| CN106310293A (zh) | 2007-09-27 | 2017-01-11 | 免疫疫苗技术有限公司 | 在包括连续疏水相的载体中的脂质体在体内输送多核苷酸中的应用 |
| KR20100127842A (ko) * | 2008-03-26 | 2010-12-06 | 유니버시티 오브 옥스퍼드 | 소포체 표적화 리포좀 |
| WO2009146523A1 (en) | 2008-06-05 | 2009-12-10 | Immunovaccine Technologies Inc. | Compositions comprising liposomes, an antigen, a polynucleotide and a carrier comprising a continuous phase of a hydrophobic substance |
| EP3058953A1 (en) * | 2009-07-07 | 2016-08-24 | The Research Foundation Of State University Of New York | Lipidic compositions for induction of immune tolerance |
| US10617640B2 (en) | 2009-07-07 | 2020-04-14 | The Research Foundation For The State University Of New York | Phosphoserine containing compositions for immune tolerance induction |
| WO2013070362A1 (en) | 2011-10-06 | 2013-05-16 | The Research Foundation Of State University Of New York | Compositions and methods for immune tolerance induction |
| CN113876945A (zh) | 2011-10-06 | 2022-01-04 | 免疫疫苗技术有限公司 | 包括激活或增加tlr2活性的佐剂的脂质体组合物及其应用 |
| MA37610B1 (fr) | 2012-05-09 | 2017-07-31 | Univ Western Health Sciences | Formulations de testostérone proliposomales |
| AU2014243701A1 (en) * | 2013-03-13 | 2015-11-05 | Stemetrix, Inc. | Skin compositions and uses |
| US20160243220A1 (en) * | 2013-09-24 | 2016-08-25 | The Research Foundation For The State University Of New York | Compositions and methods for reducing antigen-specific immunogenicity |
| CA3184687A1 (en) * | 2020-07-01 | 2022-01-06 | Sathy V. Balu-Iyer | Method for preparation of liposomes |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US4127502A (en) | 1977-06-10 | 1978-11-28 | Eastman Kodak Company | Stabilizers for reconstituted, lyophilized samples |
| US4837028A (en) * | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US4920016A (en) | 1986-12-24 | 1990-04-24 | Linear Technology, Inc. | Liposomes with enhanced circulation time |
| US4795806A (en) | 1987-07-16 | 1989-01-03 | Miles Laboratories, Inc. | Phospholipid affinity purification of Factor VIII:C |
| US5997864A (en) | 1995-06-07 | 1999-12-07 | Novo Nordisk A/S | Modified factor VII |
| AU668934B2 (en) * | 1992-04-10 | 1996-05-23 | Hisamitsu Pharmaceutical Co., Inc. | Liposome composition |
| DE4416166C2 (de) * | 1994-05-06 | 1997-11-20 | Immuno Ag | Stabiles Präparat zur Behandlung von Blutgerinnungsstörungen |
| DE4416180C2 (de) | 1994-05-06 | 1997-08-14 | Immuno Ag | Stabiles Präparat zur Behandlung von Blutgerinnungsstörungen und Verfahren zur Herstellung dieses Präparats |
| US5580856A (en) | 1994-07-15 | 1996-12-03 | Prestrelski; Steven J. | Formulation of a reconstituted protein, and method and kit for the production thereof |
| CA2181390C (en) | 1995-07-18 | 2001-04-24 | Pankaj Modi | Phospholipid formulations |
| AT403764B (de) | 1996-03-15 | 1998-05-25 | Immuno Ag | Stabiler faktor viii/vwf-komplex |
| EP0979102A4 (en) | 1997-04-30 | 2005-11-23 | Enzon Inc | DETAILED POLYPEPTIDE MODIFIED BY POLYALKYLENE OXIDE |
| US6593294B1 (en) * | 1998-04-27 | 2003-07-15 | Opperbas Holding B.V. | Pharmaceutical composition comprising Factor VIII and neutral liposomes |
| AU2002239607A1 (en) | 2000-11-30 | 2002-06-11 | Baxter Healthcare Corporation | Ahf associated dispersion system and method for preparation |
| ZA200305980B (en) | 2001-02-12 | 2007-01-31 | Res Dev Foundation | Modified proteins, designer toxins, and methods of making thereof |
| WO2003013245A1 (en) | 2001-08-07 | 2003-02-20 | Wisconsin Alumni Research Foundation | Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy |
| ES2387886T3 (es) * | 2001-11-13 | 2012-10-03 | Celator Pharmaceuticals, Inc. | Composiciones que transportan lípidos con una mejor estabilidad sanguínea |
| US7351688B2 (en) * | 2003-02-05 | 2008-04-01 | The Research Foundation Of State University Of New York | Compositions and methods for less immunogenic protein formulations |
| US20040229793A1 (en) | 2003-02-05 | 2004-11-18 | Balasubramanian Sathyamangalam V. | Compositions and methods for less immunogenic protein formulations |
| TWI433693B (zh) * | 2003-02-14 | 2014-04-11 | Childrens Hosp & Res Ct Oak | 親脂藥物傳送媒介物及其使用方法 |
| MX2007004955A (es) * | 2004-11-08 | 2007-06-14 | Transave Inc | Metodo de tratar cancer con formulaciones de compeusto de platino a base de lipido administradas intraperitonealmente. |
| CA2613705A1 (en) | 2005-06-29 | 2007-01-04 | The Research Foundation Of State University Of New York | Compositions and methods for less immunogenic pr0tein-lip1d complexes |
| WO2007117469A2 (en) * | 2006-03-30 | 2007-10-18 | The Research Foundation Of State University Of New York | Compositions of less immunogenic and long-circulating protein-lipid complexes |
| US7875288B2 (en) * | 2006-03-30 | 2011-01-25 | The Research Foundation Of State University Of New York | Method for treating blood coagulation disorders |
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2007
- 2007-03-30 WO PCT/US2007/008311 patent/WO2007117469A2/en not_active Ceased
- 2007-03-30 CA CA2660310A patent/CA2660310C/en not_active Expired - Fee Related
- 2007-03-30 JP JP2009503092A patent/JP5160534B2/ja not_active Expired - Fee Related
- 2007-03-30 AU AU2007235463A patent/AU2007235463B2/en not_active Ceased
- 2007-03-30 EP EP07754777.6A patent/EP2007357B1/en not_active Not-in-force
- 2007-03-30 NZ NZ572308A patent/NZ572308A/en not_active IP Right Cessation
- 2007-03-30 US US11/731,648 patent/US7875289B2/en not_active Expired - Fee Related
-
2010
- 2010-12-28 US US12/979,621 patent/US20110123625A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20110123625A1 (en) | 2011-05-26 |
| WO2007117469A2 (en) | 2007-10-18 |
| US20070274980A1 (en) | 2007-11-29 |
| EP2007357A4 (en) | 2013-07-17 |
| AU2007235463B2 (en) | 2012-11-22 |
| JP2009532371A (ja) | 2009-09-10 |
| JP5160534B2 (ja) | 2013-03-13 |
| AU2007235463A1 (en) | 2007-10-18 |
| WO2007117469A3 (en) | 2008-07-03 |
| CA2660310A1 (en) | 2007-10-18 |
| EP2007357A2 (en) | 2008-12-31 |
| CA2660310C (en) | 2015-04-21 |
| US7875289B2 (en) | 2011-01-25 |
| EP2007357B1 (en) | 2016-11-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) | ||
| LAPS | Patent lapsed |