NZ567048A - Novel diazabicyclic aryl derivatives and their medical use - Google Patents
Novel diazabicyclic aryl derivatives and their medical useInfo
- Publication number
- NZ567048A NZ567048A NZ567048A NZ56704806A NZ567048A NZ 567048 A NZ567048 A NZ 567048A NZ 567048 A NZ567048 A NZ 567048A NZ 56704806 A NZ56704806 A NZ 56704806A NZ 567048 A NZ567048 A NZ 567048A
- Authority
- NZ
- New Zealand
- Prior art keywords
- diaza
- bicyclo
- nonane
- methyl
- pyridazin
- Prior art date
Links
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- 239000000203 mixture Substances 0.000 claims description 44
- 150000003839 salts Chemical class 0.000 claims description 41
- 125000000217 alkyl group Chemical group 0.000 claims description 24
- 125000000623 heterocyclic group Chemical group 0.000 claims description 21
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 18
- 125000003545 alkoxy group Chemical group 0.000 claims description 15
- 239000008194 pharmaceutical composition Substances 0.000 claims description 15
- 125000002541 furyl group Chemical group 0.000 claims description 14
- 125000001624 naphthyl group Chemical group 0.000 claims description 14
- 125000000168 pyrrolyl group Chemical group 0.000 claims description 14
- 125000001544 thienyl group Chemical group 0.000 claims description 14
- 125000002837 carbocyclic group Chemical group 0.000 claims description 13
- 125000001424 substituent group Chemical group 0.000 claims description 13
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- 239000001257 hydrogen Substances 0.000 claims description 10
- 229910052739 hydrogen Inorganic materials 0.000 claims description 10
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- 125000001715 oxadiazolyl group Chemical group 0.000 claims description 10
- 125000002098 pyridazinyl group Chemical group 0.000 claims description 10
- 125000001113 thiadiazolyl group Chemical group 0.000 claims description 10
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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Landscapes
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200501724 | 2005-12-06 | ||
| US74822205P | 2005-12-08 | 2005-12-08 | |
| PCT/EP2006/069316 WO2007065892A1 (en) | 2005-12-06 | 2006-12-05 | Novel diazabicyclic aryl derivatives and their medical use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ567048A true NZ567048A (en) | 2010-12-24 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ567048A NZ567048A (en) | 2005-12-06 | 2006-12-05 | Novel diazabicyclic aryl derivatives and their medical use |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8173658B2 (https=) |
| EP (2) | EP1963323B1 (https=) |
| JP (1) | JP2009518357A (https=) |
| KR (1) | KR20080079250A (https=) |
| CN (1) | CN101305004B (https=) |
| AT (1) | ATE473978T1 (https=) |
| AU (1) | AU2006323986A1 (https=) |
| BR (1) | BRPI0617772A2 (https=) |
| CA (1) | CA2632642A1 (https=) |
| DE (1) | DE602006015523D1 (https=) |
| DK (1) | DK1963323T3 (https=) |
| NZ (1) | NZ567048A (https=) |
| RU (1) | RU2008110911A (https=) |
| WO (1) | WO2007065892A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007213670A1 (en) | 2006-02-10 | 2007-08-16 | Neurosearch A/S | 3,9-diazabicyclo[3.3.1]nonane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| AU2007213671A1 (en) | 2006-02-10 | 2007-08-16 | Neurosearch A/S | 3-heteroaryl- 3,9-diazabicyclo[3.3.1]nonane derivatives as nicotinic acetylcholine receptor agonists |
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| US3293251A (en) * | 1966-12-20 | Rearrangement process for j,b-diaza- bicyclo-(j,z,i)-octane derivatives | ||
| US5478939A (en) * | 1994-07-20 | 1995-12-26 | American Cyanamid Company | (R,R) and (S,S) 2,5-diazabicyclo [2,2,1]heptane derivatives |
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| CA2289574C (en) | 1997-05-30 | 2007-04-24 | Neurosearch A/S | 8-azabicyclo(3,2,1)oct-2-ene and octane derivatives as cholinergic ligands at nicotinic ach receptors |
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| FR2809732B1 (fr) | 2000-05-31 | 2002-07-19 | Sanofi Synthelabo | DERIVES DE 4(-2-PHENYLTHIAZOL-5-yl)-1,4-DIAZABICYCLO-[3.2.2] NONANE, LEUR PREPARATION ET LEUR APPLICATION ENTHERAPEUTIQUE |
| FR2809731B1 (fr) | 2000-05-31 | 2002-07-19 | Sanofi Synthelabo | Derives de 1,4-diazabicyclo-[3.2.2] nonane-pheylisoxazole, leur preparation et leur application en therapeutique |
| ATE287888T1 (de) * | 2000-07-04 | 2005-02-15 | Neurosearch As | Aryl- und heteroaryldiazabicycloalkane, deren zubereitung und verwendung |
| WO2002096911A1 (en) * | 2001-06-01 | 2002-12-05 | Neurosearch A/S | Novel heteroaryl-diazabicyclo-alkanes as cns-modulators |
| FR2832713B1 (fr) | 2001-11-23 | 2004-02-13 | Sanofi Synthelabo | Derives de 4-(1,3,4-thiadiazol-2-yl)-1,4-diazabicyclo[3.2.2] nonane, leur preparation et leur application en therapeutique |
| FR2832712B1 (fr) | 2001-11-23 | 2004-02-13 | Sanofi Synthelabo | Derives de 4-(oxadiazol-3-yl)-1,4-diazabicyclo[3.2.2]nonane, leur preparation et leur application en therapeutique |
| DE60310548T2 (de) | 2002-05-07 | 2007-05-10 | Neurosearch A/S | Diazabicyclische biarylderivate |
| DK1562945T3 (da) | 2002-11-11 | 2007-03-05 | Neurosearch As | Hidtil ukendte diazebicykliske biarylderivater |
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-
2006
- 2006-12-05 CA CA002632642A patent/CA2632642A1/en not_active Abandoned
- 2006-12-05 AT AT06830366T patent/ATE473978T1/de active
- 2006-12-05 EP EP06830366A patent/EP1963323B1/en not_active Not-in-force
- 2006-12-05 KR KR1020087013706A patent/KR20080079250A/ko not_active Withdrawn
- 2006-12-05 DK DK06830366.8T patent/DK1963323T3/da active
- 2006-12-05 BR BRPI0617772-7A patent/BRPI0617772A2/pt not_active IP Right Cessation
- 2006-12-05 US US12/093,655 patent/US8173658B2/en not_active Expired - Fee Related
- 2006-12-05 DE DE602006015523T patent/DE602006015523D1/de active Active
- 2006-12-05 WO PCT/EP2006/069316 patent/WO2007065892A1/en not_active Ceased
- 2006-12-05 RU RU2008110911/04A patent/RU2008110911A/ru unknown
- 2006-12-05 JP JP2008543818A patent/JP2009518357A/ja not_active Abandoned
- 2006-12-05 NZ NZ567048A patent/NZ567048A/en not_active IP Right Cessation
- 2006-12-05 CN CN2006800416608A patent/CN101305004B/zh not_active Expired - Fee Related
- 2006-12-05 EP EP10164285A patent/EP2246352A1/en not_active Withdrawn
- 2006-12-05 AU AU2006323986A patent/AU2006323986A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0617772A2 (pt) | 2011-08-09 |
| CN101305004B (zh) | 2011-11-16 |
| EP1963323A1 (en) | 2008-09-03 |
| JP2009518357A (ja) | 2009-05-07 |
| RU2008110911A (ru) | 2010-01-20 |
| EP1963323B1 (en) | 2010-07-14 |
| KR20080079250A (ko) | 2008-08-29 |
| US8173658B2 (en) | 2012-05-08 |
| WO2007065892A1 (en) | 2007-06-14 |
| US20080280912A1 (en) | 2008-11-13 |
| DE602006015523D1 (de) | 2010-08-26 |
| CA2632642A1 (en) | 2007-06-14 |
| EP2246352A1 (en) | 2010-11-03 |
| CN101305004A (zh) | 2008-11-12 |
| ATE473978T1 (de) | 2010-07-15 |
| DK1963323T3 (da) | 2010-10-25 |
| AU2006323986A1 (en) | 2007-06-14 |
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| Date | Code | Title | Description |
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| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) | ||
| LAPS | Patent lapsed |