NZ546552A - A method for increasing CD8+ cytotoxic T cell reponses and for treating multiple sclerosis - Google Patents

A method for increasing CD8+ cytotoxic T cell reponses and for treating multiple sclerosis

Info

Publication number
NZ546552A
NZ546552A NZ546552A NZ54655204A NZ546552A NZ 546552 A NZ546552 A NZ 546552A NZ 546552 A NZ546552 A NZ 546552A NZ 54655204 A NZ54655204 A NZ 54655204A NZ 546552 A NZ546552 A NZ 546552A
Authority
NZ
New Zealand
Prior art keywords
cells
mbp
autologous
cell
associated antigen
Prior art date
Application number
NZ546552A
Other languages
English (en)
Inventor
Ying Zang
Original Assignee
Baylor College Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor College Medicine filed Critical Baylor College Medicine
Publication of NZ546552A publication Critical patent/NZ546552A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0008Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/20Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/22Immunosuppressive or immunotolerising
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/416Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/45Bacterial antigens
    • A61K40/453Clostridium, e.g. Clostridium tetani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NZ546552A 2003-10-17 2004-10-18 A method for increasing CD8+ cytotoxic T cell reponses and for treating multiple sclerosis NZ546552A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51221203P 2003-10-17 2003-10-17
PCT/US2004/034448 WO2005037309A1 (en) 2003-10-17 2004-10-18 A method for increasing cd8+ cytotoxic t cell reponses and for treating multiple sclerosis

Publications (1)

Publication Number Publication Date
NZ546552A true NZ546552A (en) 2009-10-30

Family

ID=34465326

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ546552A NZ546552A (en) 2003-10-17 2004-10-18 A method for increasing CD8+ cytotoxic T cell reponses and for treating multiple sclerosis

Country Status (10)

Country Link
US (2) US20080107664A1 (enExample)
EP (1) EP1677821B1 (enExample)
JP (1) JP2007509063A (enExample)
CN (1) CN1893971A (enExample)
AU (1) AU2004281817B2 (enExample)
BR (1) BRPI0415519A (enExample)
CA (1) CA2542668C (enExample)
IL (1) IL174935A (enExample)
NZ (1) NZ546552A (enExample)
WO (1) WO2005037309A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004281817B2 (en) * 2003-10-17 2010-07-22 Baylor College Of Medicine A method for increasing CD8+ cytotoxic T cell reponses and for treating multiple sclerosis
ES2552667T3 (es) * 2006-05-05 2015-12-01 Opexa Therapeutics Vacuna de células T
EP2050814A1 (en) * 2007-10-17 2009-04-22 Txcell Compositions for treating multiple sclerosis
AU2010319323B2 (en) * 2009-11-14 2015-01-15 Cardiovax, Llc Immunomodulatory methods and systems for treatment and/or prevention of atherosclerosis
RU2435556C1 (ru) * 2010-04-23 2011-12-10 Владимир Васильевич Лантух Способ лечения дистрофических заболеваний заднего полюса глаза
WO2013063713A1 (zh) * 2011-10-31 2013-05-10 鑫品生医科技股份有限公司 诱发产生综合免疫细胞的方法
CN105085616A (zh) * 2014-05-23 2015-11-25 上海市普陀区中心医院 一种氨基酸序列及其应用
CN105085615A (zh) * 2014-05-23 2015-11-25 上海市普陀区中心医院 一种多肽序列及其应用
EP3570852B1 (en) * 2017-01-20 2025-07-30 Atara Biotherapeutics, Inc. Autologous cytotoxic t cells (ctls) expressing an ebv-binding t cell receptor for use in treating or preventing primary progressive multiple sclerosis (ms) or secondary progressive ms

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3434510B2 (ja) 1992-04-09 2003-08-11 オートイミューン インク ミエリン塩基性タンパク質のペプチドフラグメントを用いたt‐細胞増殖の抑制
US6410518B1 (en) * 1994-05-31 2002-06-25 Isis Pharmaceuticals, Inc. Antisense oligonucleotide inhibition of raf gene expression
US20020042423A1 (en) 1998-04-29 2002-04-11 John R. Richert Methods for identifying compounds that bind to hla molecules and use of such compounds as hla-agonists or antagonists
AU2002308732A1 (en) * 2001-05-15 2002-11-25 Ortho-Mcneil Pharmaceutical, Inc. Ex-vivo priming for generating cytotoxic t lymphocytes specific for non-tumor antigens to treat autoimmune and allergic disease
US7658926B2 (en) * 2001-09-14 2010-02-09 Opexa Pharmaceuticals, Inc. Autologous T-cell vaccines materials and methods
IL164376A0 (en) 2002-04-03 2005-12-18 Applied Research Systems Ox4or binding agents, their preparation and pharmaceutical compositions containing them
AU2004281817B2 (en) * 2003-10-17 2010-07-22 Baylor College Of Medicine A method for increasing CD8+ cytotoxic T cell reponses and for treating multiple sclerosis

Also Published As

Publication number Publication date
CA2542668A1 (en) 2005-04-28
CA2542668C (en) 2014-04-29
WO2005037309A1 (en) 2005-04-28
EP1677821B1 (en) 2013-02-27
CN1893971A (zh) 2007-01-10
BRPI0415519A (pt) 2006-12-26
JP2007509063A (ja) 2007-04-12
IL174935A0 (en) 2006-08-20
EP1677821A1 (en) 2006-07-12
AU2004281817A1 (en) 2005-04-28
IL174935A (en) 2012-01-31
US20100183546A1 (en) 2010-07-22
AU2004281817B2 (en) 2010-07-22
US20080107664A1 (en) 2008-05-08

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Legal Events

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Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 18 OCT 2017 BY CPA GLOBAL

Effective date: 20140903

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