NZ546552A - A method for increasing CD8+ cytotoxic T cell reponses and for treating multiple sclerosis - Google Patents

A method for increasing CD8+ cytotoxic T cell reponses and for treating multiple sclerosis

Info

Publication number
NZ546552A
NZ546552A NZ546552A NZ54655204A NZ546552A NZ 546552 A NZ546552 A NZ 546552A NZ 546552 A NZ546552 A NZ 546552A NZ 54655204 A NZ54655204 A NZ 54655204A NZ 546552 A NZ546552 A NZ 546552A
Authority
NZ
New Zealand
Prior art keywords
cells
mbp
autologous
cell
associated antigen
Prior art date
Application number
NZ546552A
Other languages
English (en)
Inventor
Ying Zang
Original Assignee
Baylor College Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor College Medicine filed Critical Baylor College Medicine
Publication of NZ546552A publication Critical patent/NZ546552A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/22—Immunosuppressive or immunotolerising
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/416—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/45—Bacterial antigens
    • A61K40/453—Clostridium, e.g. Clostridium tetani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NZ546552A 2003-10-17 2004-10-18 A method for increasing CD8+ cytotoxic T cell reponses and for treating multiple sclerosis NZ546552A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51221203P 2003-10-17 2003-10-17
PCT/US2004/034448 WO2005037309A1 (en) 2003-10-17 2004-10-18 A method for increasing cd8+ cytotoxic t cell reponses and for treating multiple sclerosis

Publications (1)

Publication Number Publication Date
NZ546552A true NZ546552A (en) 2009-10-30

Family

ID=34465326

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ546552A NZ546552A (en) 2003-10-17 2004-10-18 A method for increasing CD8+ cytotoxic T cell reponses and for treating multiple sclerosis

Country Status (10)

Country Link
US (2) US20080107664A1 (enExample)
EP (1) EP1677821B1 (enExample)
JP (1) JP2007509063A (enExample)
CN (1) CN1893971A (enExample)
AU (1) AU2004281817B2 (enExample)
BR (1) BRPI0415519A (enExample)
CA (1) CA2542668C (enExample)
IL (1) IL174935A (enExample)
NZ (1) NZ546552A (enExample)
WO (1) WO2005037309A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007509063A (ja) * 2003-10-17 2007-04-12 ベイラー カレッジ オブ メディスン Cd8+細胞傷害性t細胞応答を増大させる方法、および多発性硬化症を処置するための方法
CA2651328A1 (en) * 2006-05-05 2007-11-15 Opexa Therapeutics T-cell vaccine
EP2050814A1 (en) * 2007-10-17 2009-04-22 Txcell Compositions for treating multiple sclerosis
AU2010319323B2 (en) * 2009-11-14 2015-01-15 Cardiovax, Llc Immunomodulatory methods and systems for treatment and/or prevention of atherosclerosis
RU2435556C1 (ru) * 2010-04-23 2011-12-10 Владимир Васильевич Лантух Способ лечения дистрофических заболеваний заднего полюса глаза
WO2013063713A1 (zh) * 2011-10-31 2013-05-10 鑫品生医科技股份有限公司 诱发产生综合免疫细胞的方法
CN105085615A (zh) * 2014-05-23 2015-11-25 上海市普陀区中心医院 一种多肽序列及其应用
CN105085616A (zh) * 2014-05-23 2015-11-25 上海市普陀区中心医院 一种氨基酸序列及其应用
CA3050299A1 (en) * 2017-01-20 2018-07-26 Atara Biotherapeutics, Inc. Methods of treating multiple sclerosis using autologous t cells

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69331501T2 (de) 1992-04-09 2002-08-29 Autoimmune, Inc. Unterdrückung der Proliferation von T-Zellen mittels Peptidfragmenten des basischen Proteins aus Myelin
US6410518B1 (en) * 1994-05-31 2002-06-25 Isis Pharmaceuticals, Inc. Antisense oligonucleotide inhibition of raf gene expression
CA2330458A1 (en) 1998-04-29 1999-11-04 Georgetown University Methods of identifying and using hla binding compounds as hla-agonists and antagonists
ATE438710T1 (de) * 2001-05-15 2009-08-15 Ortho Mcneil Janssen Pharm Ex-vivo-priming zur erzeugung cd40-ligand spezifischer zytotoxischer t-lymphozyten zur behandlung von autoimmun- und allergischen erkrankungen
US7658926B2 (en) * 2001-09-14 2010-02-09 Opexa Pharmaceuticals, Inc. Autologous T-cell vaccines materials and methods
IL164376A0 (en) 2002-04-03 2005-12-18 Applied Research Systems Ox4or binding agents, their preparation and pharmaceutical compositions containing them
JP2007509063A (ja) * 2003-10-17 2007-04-12 ベイラー カレッジ オブ メディスン Cd8+細胞傷害性t細胞応答を増大させる方法、および多発性硬化症を処置するための方法

Also Published As

Publication number Publication date
BRPI0415519A (pt) 2006-12-26
US20100183546A1 (en) 2010-07-22
EP1677821A1 (en) 2006-07-12
IL174935A (en) 2012-01-31
CN1893971A (zh) 2007-01-10
CA2542668C (en) 2014-04-29
US20080107664A1 (en) 2008-05-08
CA2542668A1 (en) 2005-04-28
JP2007509063A (ja) 2007-04-12
IL174935A0 (en) 2006-08-20
AU2004281817B2 (en) 2010-07-22
EP1677821B1 (en) 2013-02-27
WO2005037309A1 (en) 2005-04-28
AU2004281817A1 (en) 2005-04-28

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Legal Events

Date Code Title Description
PSEA Patent sealed
RENW Renewal (renewal fees accepted)
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Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 18 OCT 2017 BY CPA GLOBAL

Effective date: 20140903

LAPS Patent lapsed