NZ535684A - Use of a GLP-1 (glucagon like peptide-1) compound to treat gastroparesis by increasing gastric emptying - Google Patents
Use of a GLP-1 (glucagon like peptide-1) compound to treat gastroparesis by increasing gastric emptyingInfo
- Publication number
- NZ535684A NZ535684A NZ535684A NZ53568403A NZ535684A NZ 535684 A NZ535684 A NZ 535684A NZ 535684 A NZ535684 A NZ 535684A NZ 53568403 A NZ53568403 A NZ 53568403A NZ 535684 A NZ535684 A NZ 535684A
- Authority
- NZ
- New Zealand
- Prior art keywords
- glp
- glucagon
- peptide
- gastric emptying
- compound
- Prior art date
Links
- DTHNMHAUYICORS-KTKZVXAJSA-N Glucagon-like peptide 1 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 DTHNMHAUYICORS-KTKZVXAJSA-N 0.000 title abstract 5
- 101800000224 Glucagon-like peptide 1 Proteins 0.000 title abstract 3
- 206010021518 Impaired gastric emptying Diseases 0.000 title abstract 3
- 102100040918 Pro-glucagon Human genes 0.000 title abstract 3
- 230000030136 gastric emptying Effects 0.000 title abstract 3
- 208000001288 gastroparesis Diseases 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Nutrition Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37165002P | 2002-04-10 | 2002-04-10 | |
PCT/US2003/008457 WO2003087139A2 (en) | 2002-04-10 | 2003-03-27 | Treatment of gastroparesis |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ535684A true NZ535684A (en) | 2006-03-31 |
Family
ID=29250714
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ535684A NZ535684A (en) | 2002-04-10 | 2003-03-27 | Use of a GLP-1 (glucagon like peptide-1) compound to treat gastroparesis by increasing gastric emptying |
Country Status (18)
Country | Link |
---|---|
US (1) | US20050164925A1 (ko) |
EP (1) | EP1496924A4 (ko) |
JP (1) | JP2005530732A (ko) |
KR (1) | KR20040098063A (ko) |
CN (1) | CN1735423A (ko) |
AU (1) | AU2003220403A1 (ko) |
BR (1) | BR0308904A (ko) |
CA (1) | CA2480858A1 (ko) |
EA (1) | EA200401345A1 (ko) |
EC (1) | ECSP045345A (ko) |
HR (1) | HRP20040939A2 (ko) |
IL (1) | IL164266A0 (ko) |
MX (1) | MXPA04009929A (ko) |
NO (1) | NO20044815L (ko) |
NZ (1) | NZ535684A (ko) |
PL (1) | PL373658A1 (ko) |
WO (1) | WO2003087139A2 (ko) |
ZA (1) | ZA200408111B (ko) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8666495B2 (en) | 1999-03-05 | 2014-03-04 | Metacure Limited | Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar |
US9101765B2 (en) | 1999-03-05 | 2015-08-11 | Metacure Limited | Non-immediate effects of therapy |
US8792985B2 (en) | 2003-07-21 | 2014-07-29 | Metacure Limited | Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar |
KR101241862B1 (ko) * | 2003-09-19 | 2013-03-13 | 노보 노르디스크 에이/에스 | 신규 glp-1 유도체 |
TW200522976A (en) | 2003-09-19 | 2005-07-16 | Novo Nordisk As | Novel plasma protein affinity tags |
ATE532459T1 (de) | 2004-08-18 | 2011-11-15 | Metacure Ltd | Überwachung, analyse und regulierung von essgewohnheiten |
US9821158B2 (en) | 2005-02-17 | 2017-11-21 | Metacure Limited | Non-immediate effects of therapy |
WO2006087712A2 (en) | 2005-02-17 | 2006-08-24 | Metacure N.V. | Charger with data transfer capabilities |
WO2006097538A1 (en) | 2005-03-18 | 2006-09-21 | Novo Nordisk A/S | Extended glp-1 compounds |
TWI372629B (en) | 2005-03-18 | 2012-09-21 | Novo Nordisk As | Acylated glp-1 compounds |
WO2006102626A2 (en) * | 2005-03-24 | 2006-09-28 | Metacure Nv | Wireless leads for gastrointestinal tract applications |
WO2007080595A2 (en) | 2006-01-12 | 2007-07-19 | Metacure N.V. | Electrode assemblies, tools, and methods for gastric wall implantation |
EP1890763A4 (en) | 2005-06-02 | 2017-05-03 | Metacure Limited | Gi lead implantation |
US8442841B2 (en) * | 2005-10-20 | 2013-05-14 | Matacure N.V. | Patient selection method for assisting weight loss |
US8295932B2 (en) | 2005-12-05 | 2012-10-23 | Metacure Limited | Ingestible capsule for appetite regulation |
AU2012203915B9 (en) * | 2006-04-20 | 2014-10-09 | Amgen Inc. | GLP-1 compounds |
EP2574624A1 (en) * | 2006-04-20 | 2013-04-03 | Amgen Inc. | GLP-1 compounds |
US8417329B2 (en) * | 2007-05-09 | 2013-04-09 | Metacure Ltd. | Analysis and regulation of food intake |
US8423130B2 (en) * | 2008-05-09 | 2013-04-16 | Metacure Limited | Optimization of thresholds for eating detection |
CA2733200A1 (en) | 2008-08-06 | 2010-02-11 | Novo Nordisk Health Care Ag | Conjugated proteins with prolonged in vivo efficacy |
CN102292349B (zh) | 2009-01-22 | 2016-04-13 | 诺沃—诺迪斯克保健股份有限公司 | 稳定的生长激素化合物 |
CN102612376A (zh) | 2009-08-06 | 2012-07-25 | 诺沃-诺迪斯克保健股份有限公司 | 具有延长的体内功效的生长激素 |
WO2011017554A2 (en) * | 2009-08-07 | 2011-02-10 | Mannkind Corporation | Val (8) glp-1 composition and method for treating functional dyspepsia and/or irritable bowel syndrome |
CN106139158A (zh) | 2010-01-22 | 2016-11-23 | 诺沃—诺迪斯克保健股份有限公司 | 体内功效延长的生长激素 |
EP2525833A2 (en) | 2010-01-22 | 2012-11-28 | Novo Nordisk Health Care AG | Stable growth hormone compounds |
US8934975B2 (en) | 2010-02-01 | 2015-01-13 | Metacure Limited | Gastrointestinal electrical therapy |
KR20130093470A (ko) | 2010-04-30 | 2013-08-22 | 가부시키가이샤산와카가쿠켄큐쇼 | 생리활성 물질 등의 생체 내 안정성 향상을 위한 펩티드 및 생체 내 안정성이 향상된 생리활성 물질 |
UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
ES2688367T3 (es) | 2012-12-21 | 2018-11-02 | Sanofi | Derivados de exendina-4 como agonistas duales de GLP1/GIP o trigonales de GLP1/GIP/glucagón |
US11045523B2 (en) | 2013-04-05 | 2021-06-29 | Novo Nordisk Healthcare Ag | Formulation of growth hormone albumin-binder conjugate |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6268343B1 (en) * | 1996-08-30 | 2001-07-31 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
US5981488A (en) * | 1997-03-31 | 1999-11-09 | Eli Lillly And Company | Glucagon-like peptide-1 analogs |
IL142707A0 (en) * | 2000-04-27 | 2002-03-10 | Pfizer Prod Inc | Methods of treating obesity using a neurotensin receptor ligand |
-
2003
- 2003-03-27 BR BR0308904-5A patent/BR0308904A/pt not_active IP Right Cessation
- 2003-03-27 JP JP2003584094A patent/JP2005530732A/ja active Pending
- 2003-03-27 KR KR10-2004-7016025A patent/KR20040098063A/ko not_active Application Discontinuation
- 2003-03-27 CN CNA038080079A patent/CN1735423A/zh active Pending
- 2003-03-27 AU AU2003220403A patent/AU2003220403A1/en not_active Abandoned
- 2003-03-27 PL PL03373658A patent/PL373658A1/xx unknown
- 2003-03-27 NZ NZ535684A patent/NZ535684A/xx unknown
- 2003-03-27 CA CA002480858A patent/CA2480858A1/en not_active Abandoned
- 2003-03-27 EA EA200401345A patent/EA200401345A1/ru unknown
- 2003-03-27 WO PCT/US2003/008457 patent/WO2003087139A2/en not_active Application Discontinuation
- 2003-03-27 US US10/508,762 patent/US20050164925A1/en not_active Abandoned
- 2003-03-27 EP EP03716707A patent/EP1496924A4/en not_active Withdrawn
- 2003-03-27 MX MXPA04009929A patent/MXPA04009929A/es not_active Application Discontinuation
- 2003-03-27 IL IL16426603A patent/IL164266A0/xx unknown
-
2004
- 2004-10-07 ZA ZA200408111A patent/ZA200408111B/xx unknown
- 2004-10-07 HR HRP20040939 patent/HRP20040939A2/hr not_active Application Discontinuation
- 2004-10-08 EC EC2004005345A patent/ECSP045345A/es unknown
- 2004-11-05 NO NO20044815A patent/NO20044815L/no unknown
Also Published As
Publication number | Publication date |
---|---|
BR0308904A (pt) | 2005-05-03 |
NO20044815L (no) | 2005-01-07 |
WO2003087139A3 (en) | 2004-01-08 |
AU2003220403A1 (en) | 2003-10-27 |
MXPA04009929A (es) | 2006-03-10 |
ECSP045345A (es) | 2006-04-19 |
WO2003087139A2 (en) | 2003-10-23 |
EA200401345A1 (ru) | 2005-08-25 |
KR20040098063A (ko) | 2004-11-18 |
ZA200408111B (en) | 2005-10-07 |
CA2480858A1 (en) | 2003-10-23 |
IL164266A0 (en) | 2005-12-18 |
EP1496924A4 (en) | 2007-05-30 |
HRP20040939A2 (en) | 2004-12-31 |
CN1735423A (zh) | 2006-02-15 |
EP1496924A2 (en) | 2005-01-19 |
JP2005530732A (ja) | 2005-10-13 |
PL373658A1 (en) | 2005-09-05 |
US20050164925A1 (en) | 2005-07-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NZ535684A (en) | Use of a GLP-1 (glucagon like peptide-1) compound to treat gastroparesis by increasing gastric emptying | |
PH12021550154A1 (en) | Gip/glp1 co-agonist compounds. | |
MY137350A (en) | Glucagon-like peptide-1 analogs | |
WO2005012249A3 (en) | Adamantyglycine- based inhibitors of dipeptidyl peptidase iv for the treatment of diabetes | |
PT1928499E (pt) | Utilização de um inibidor da dpp-iv para reduzir eventos hipoglicémicos | |
DE68929217D1 (en) | Insulinotropes hormon | |
NZ732000A (en) | Gip and glp-1 co-agonist compounds | |
HK1100353A1 (en) | Combination therapy for the treatment of diabetes and conditions related thereto and for the treatment of conditions ameliorated by increasing a blood glp-1 level | |
IL153529A0 (en) | Combinations of dipeptidyl peptidase iv inhibitors and other antidiabetic agents for the treatment of diabetes mellitus | |
MY136926A (en) | Glucokinase activators | |
EP1406622A4 (en) | DIPEPTIDYLPEPTIDASE INHIBITORS FOR THE TREATMENT OF DIABETES | |
NO20015607D0 (no) | Glukagonantagonister/inversagonister | |
MY137757A (en) | Therapeutic treatment | |
WO2003061362A3 (en) | Methods and compositions for treating polycystic ovary syndrome | |
SI1133312T1 (sl) | Uporaba tiazolidindionov v kombinaciji z glukagonu podobnim peptidom-1 in njegovimi agonisti za zdravljenje sladkorne bolezni, neodvisne od inzulina | |
MXPA05013734A (es) | Hexahidropiroisoquinolinas como inhibidores de dpp-iv. | |
HK1046640A1 (zh) | 用glp-1進行代謝介入以提高缺血和再灌注組織的功能 | |
IS2793B (is) | Notkun á 3-hýdroxý-3-metýlglútarýl hjálparensíms A afsýringarkljúfshindrum til framleiðslunnar á lyfi til að meðhöndla sykursýkitaugakvilla | |
WO2004050115A3 (en) | Combination treatment using exendin-4 and thiazolidinediones | |
AU2003203146A1 (en) | Use of glp-1 compound for treatment of critically ill patients | |
WO2004002421A3 (en) | Method for the treatment of multiple sclerosis | |
NZ528164A (en) | Use of flumazenil to produce a medicament for the treatment of cocaine dependency | |
GB0323979D0 (en) | Therapeutic applications for c-peptide | |
SI1572622T1 (sl) | Sol levalbuterola | |
HK1070594A1 (en) | Treatment of type i diabetes mellitus using growthhormone antagonists |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PSEA | Patent sealed |