NZ525380A - Non-fucosylated forms of Cripto and their use as tumor blocking agents - Google Patents
Non-fucosylated forms of Cripto and their use as tumor blocking agentsInfo
- Publication number
- NZ525380A NZ525380A NZ525380A NZ52538001A NZ525380A NZ 525380 A NZ525380 A NZ 525380A NZ 525380 A NZ525380 A NZ 525380A NZ 52538001 A NZ52538001 A NZ 52538001A NZ 525380 A NZ525380 A NZ 525380A
- Authority
- NZ
- New Zealand
- Prior art keywords
- seq
- cripto
- polypeptide
- amino acid
- cancer
- Prior art date
Links
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23314800P | 2000-09-18 | 2000-09-18 | |
| PCT/US2001/029066 WO2002022808A2 (en) | 2000-09-18 | 2001-09-18 | Cripto mutant and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ525380A true NZ525380A (en) | 2008-06-30 |
Family
ID=22876077
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ525380A NZ525380A (en) | 2000-09-18 | 2001-09-18 | Non-fucosylated forms of Cripto and their use as tumor blocking agents |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7604931B2 (OSRAM) |
| EP (1) | EP1320604A2 (OSRAM) |
| JP (1) | JP2004524810A (OSRAM) |
| AU (2) | AU9272401A (OSRAM) |
| CA (1) | CA2422814A1 (OSRAM) |
| NZ (1) | NZ525380A (OSRAM) |
| WO (1) | WO2002022808A2 (OSRAM) |
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| JP4307845B2 (ja) | 2001-04-26 | 2009-08-05 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | Ｃｒｉｐｔｏをブロックする抗体およびその使用 |
| US20050276812A1 (en) | 2004-06-01 | 2005-12-15 | Genentech, Inc. | Antibody-drug conjugates and methods |
| WO2005028433A2 (en) * | 2003-09-15 | 2005-03-31 | Research Development Foundation | CRIPTO ANTAGONISM OF ACTIVIN AND TGF-β SIGNALING |
| WO2005033341A2 (en) * | 2003-10-03 | 2005-04-14 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Use of cripto-1 as a biomarker for neurodegenerative disease and method of inhibiting progression thereof |
| SG149815A1 (en) | 2003-11-06 | 2009-02-27 | Seattle Genetics Inc | Monomethylvaline compounds capable of conjugation to ligands |
| TR201808537T4 (tr) | 2004-09-23 | 2018-07-23 | Genentech Inc | Sistein değiştirilmiş antikorlar ve konjugatlar. |
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| WO2006074341A2 (en) * | 2005-01-07 | 2006-07-13 | Glaxo Group Limited | Novel use |
| WO2007127461A2 (en) * | 2006-04-28 | 2007-11-08 | Biogen Idec Ma Inc. | Composition and methods for the detection of cripto-3 |
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| CA2894961C (en) | 2012-12-21 | 2020-09-15 | Spirogen Sarl | Pyrrolobenzodiazepines and conjugates thereof |
| EA032986B1 (ru) | 2012-12-21 | 2019-08-30 | Медимьюн Лимитед | Пирролобензодиазепины |
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| MX362970B (es) | 2013-03-13 | 2019-02-28 | Medimmune Ltd | Pirrolobenzodiazepinas y conjugados de las mismas. |
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| EP3033111B1 (en) | 2013-08-12 | 2019-03-13 | Genentech, Inc. | 1-(chloromethyl)-2,3-dihydro-1h-benzo[e]indole dimer antibody-drug conjugate compounds, and methods of use and treatment |
| EP3054986B1 (en) | 2013-10-11 | 2019-03-20 | Medimmune Limited | Pyrrolobenzodiazepine-antibody conjugates |
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| WO2015095227A2 (en) | 2013-12-16 | 2015-06-25 | Genentech, Inc. | Peptidomimetic compounds and antibody-drug conjugates thereof |
| BR112016013258A2 (pt) | 2013-12-16 | 2018-01-16 | Genentech Inc | composto conjugado anticorpo-droga, composição farmacêutica, método para tratar câncer e kit |
| CN105873614B (zh) | 2013-12-16 | 2020-10-30 | 基因泰克公司 | 肽模拟化合物及其抗体-药物缀合物 |
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| BR112017003236A2 (pt) | 2014-09-12 | 2017-11-28 | Genentech Inc | anticorpos elaborados com cisteína, conjugados de droga e anticorpos, método de preparação de conjugado de droga e anticorpo e composição farmacêutica |
| US10149913B2 (en) | 2014-09-12 | 2018-12-11 | Genentech, Inc. | Anthracycline disulfide intermediates, antibody-drug conjugates and methods |
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| US11370801B2 (en) | 2017-04-18 | 2022-06-28 | Medimmune Limited | Pyrrolobenzodiazepine conjugates |
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| JP7145891B2 (ja) | 2017-06-14 | 2022-10-03 | アーデーセー セラピューティクス ソシエテ アノニム | 抗ｃｄ１９ ａｄｃを投与するための投与レジメ |
| PT3668874T (pt) | 2017-08-18 | 2022-02-24 | Medimmune Ltd | Conjugados de pirrolobenzodiazepina |
| EP3684773A1 (en) | 2017-09-20 | 2020-07-29 | pH Pharma Co., Ltd. | Thailanstatin analogs |
| GB201803342D0 (en) | 2018-03-01 | 2018-04-18 | Medimmune Ltd | Methods |
| GB201806022D0 (en) | 2018-04-12 | 2018-05-30 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
| GB201814281D0 (en) | 2018-09-03 | 2018-10-17 | Femtogenix Ltd | Cytotoxic agents |
| WO2020086858A1 (en) | 2018-10-24 | 2020-04-30 | Genentech, Inc. | Conjugated chemical inducers of degradation and methods of use |
| CN113227119A (zh) | 2018-12-10 | 2021-08-06 | 基因泰克公司 | 用于与含Fc的蛋白质进行位点特异性缀合的光交联肽 |
| GB201901197D0 (en) | 2019-01-29 | 2019-03-20 | Femtogenix Ltd | G-A Crosslinking cytotoxic agents |
| MX2021010477A (es) | 2019-03-15 | 2021-10-01 | Medimmune Ltd | Dimeros de azetidobenzodiazepina y conjugados que los comprenden para uso en el tratamiento de cancer. |
| GB2597532A (en) | 2020-07-28 | 2022-02-02 | Femtogenix Ltd | Cytotoxic compounds |
| EP4426727A2 (en) | 2021-11-03 | 2024-09-11 | Hangzhou Dac Biotech Co., Ltd. | Specific conjugation of an antibody |
| IT202200007580A1 (it) * | 2022-04-15 | 2023-10-15 | Consiglio Nazionale Ricerche | Vescicole lipidiche per l’uso nel trattamento terapeutico di tumori aggressivi |
| CN120417934A (zh) | 2022-12-23 | 2025-08-01 | 基因泰克公司 | Cereblon降解剂缀合物及其用途 |
| AU2024257248A1 (en) | 2023-04-17 | 2025-11-06 | Peak Bio, Inc. | Antibodies and antibody-drug conjugates and methods of use and synthetic processes and intermediates |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5256643A (en) * | 1990-05-29 | 1993-10-26 | The Government Of The United States | Human cripto protein |
| US5264557A (en) * | 1991-08-23 | 1993-11-23 | The United States Of America As Represented By The Department Of Health And Human Services | Polypeptide of a human cripto-related gene, CR-3 |
| WO1996039420A1 (en) * | 1995-06-05 | 1996-12-12 | Human Genome Sciences, Inc. | Human criptin growth factor |
| EP0942992B1 (en) * | 1997-01-31 | 2007-03-07 | Genentech, Inc. | O-fucosyltransferase |
| US6423685B1 (en) * | 1998-03-05 | 2002-07-23 | Chiron Corporation | Method for increasing the serum half-life of a biologically active molecule |
| IL125608A0 (en) * | 1998-07-30 | 1999-03-12 | Yeda Res & Dev | Tumor associated antigen peptides and use of same as anti-tumor vaccines |
-
2001
- 2001-09-18 NZ NZ525380A patent/NZ525380A/en unknown
- 2001-09-18 EP EP01973111A patent/EP1320604A2/en not_active Withdrawn
- 2001-09-18 CA CA002422814A patent/CA2422814A1/en not_active Abandoned
- 2001-09-18 WO PCT/US2001/029066 patent/WO2002022808A2/en not_active Ceased
- 2001-09-18 AU AU9272401A patent/AU9272401A/xx active Pending
- 2001-09-18 JP JP2002527250A patent/JP2004524810A/ja active Pending
- 2001-09-18 AU AU2001292724A patent/AU2001292724B2/en not_active Ceased
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2003
- 2003-03-17 US US10/390,566 patent/US7604931B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001292724B2 (en) | 2005-05-26 |
| US20030232755A1 (en) | 2003-12-18 |
| WO2002022808A2 (en) | 2002-03-21 |
| EP1320604A2 (en) | 2003-06-25 |
| JP2004524810A (ja) | 2004-08-19 |
| US7604931B2 (en) | 2009-10-20 |
| WO2002022808A3 (en) | 2003-01-16 |
| CA2422814A1 (en) | 2002-03-21 |
| AU9272401A (en) | 2002-03-26 |
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| RENW | Renewal (renewal fees accepted) |