NZ515202A - Method for detecting and killing epithelial cancer cells - Google Patents

Method for detecting and killing epithelial cancer cells

Info

Publication number
NZ515202A
NZ515202A NZ515202A NZ51520201A NZ515202A NZ 515202 A NZ515202 A NZ 515202A NZ 515202 A NZ515202 A NZ 515202A NZ 51520201 A NZ51520201 A NZ 51520201A NZ 515202 A NZ515202 A NZ 515202A
Authority
NZ
New Zealand
Prior art keywords
marking agent
mitochondrial
agent
cells
cationic
Prior art date
Application number
NZ515202A
Other languages
English (en)
Inventor
Samuel D Bernal
Douglas D Burkett
Ralph E Green
Seth D Rose
Original Assignee
Zila Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zila Inc filed Critical Zila Inc
Publication of NZ515202A publication Critical patent/NZ515202A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/006—Biological staining of tissues in vivo, e.g. methylene blue or toluidine blue O administered in the buccal area to detect epithelial cancer cells, dyes used for delineating tissues during surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
NZ515202A 2000-02-28 2001-02-27 Method for detecting and killing epithelial cancer cells NZ515202A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US2000/005387 WO2001064110A1 (en) 2000-02-28 2000-02-28 Method for detecting and killing epithelial cancer cells
PCT/US2001/006318 WO2001064255A1 (en) 2000-02-28 2001-02-27 Method for detecting and killing epithelial cancer cells

Publications (1)

Publication Number Publication Date
NZ515202A true NZ515202A (en) 2003-05-30

Family

ID=21741108

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ515202A NZ515202A (en) 2000-02-28 2001-02-27 Method for detecting and killing epithelial cancer cells

Country Status (14)

Country Link
EP (1) EP1214101A4 (de)
JP (1) JP2003525044A (de)
KR (2) KR100907122B1 (de)
CN (1) CN100544770C (de)
AU (2) AU2000237154A1 (de)
BR (1) BR0104747A (de)
CA (1) CA2370741A1 (de)
CZ (1) CZ20013861A3 (de)
IL (1) IL146141A0 (de)
MX (1) MXPA01010886A (de)
NO (1) NO20015242L (de)
NZ (1) NZ515202A (de)
RU (1) RU2226404C2 (de)
WO (2) WO2001064110A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2000237154A1 (en) * 2000-02-28 2001-09-12 Zila, Inc. Method for detecting and killing epithelial cancer cells
AU784558B2 (en) * 2000-06-30 2006-05-04 Zila Biotechnology, Inc. Rhodamine diagnostic agent and diagnostic methods for detections of epithelial cancer
EP1322339A4 (de) * 2000-09-26 2004-05-26 Zila Inc METHODE ZUR FRüHEN VORHERSAGE DES AUFTRETENS VON INVASIVEM KREBS.
CA2457907A1 (en) * 2001-12-14 2003-09-04 Zila, Inc. Stain-directed molecular analysis for cancer prognosis and diagnosis
US6929817B2 (en) 2002-05-14 2005-08-16 National Starch & Chemical Investment Holding Corporation Slowly digestible starch product
US7081261B2 (en) * 2002-05-14 2006-07-25 National Starch And Chemical Investment Holding Corporation Resistant starch prepared by isoamylase debranching of low amylose starch
US6890571B2 (en) 2002-05-14 2005-05-10 National Starch And Chemical Investment Holding Corporation Slowly digestible starch product
IL165516A0 (en) * 2002-06-04 2006-01-15 Zila Inc Toluidine blue o drug substance and use thereof for in vivo staining and chemotherapeutic treatment of dysplastic tissues
BRPI0419122A (pt) * 2004-09-30 2007-12-11 Zila Biotechnology Inc método direcionado por luz para detectar e ajudar uma avaliação adicional de tecido mucoso anormal
WO2006072625A2 (en) 2005-01-06 2006-07-13 Novo Nordisk A/S Anti-kir combination treatments and methods
RU2367365C1 (ru) * 2008-03-19 2009-09-20 Государственное образовательное учреждение высшего профессионального образования "БАШКИРСКИЙ ГОСУДАРСТВЕННЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ Федерального Агентства по здравоохранению и социальному развитию" (ГОУ ВПО БГМУ РОСЗДРАВА) Способ хирургического лечения плоскоклеточного рака кожи без метастазов в регионарные лимфатические узлы
WO2011008086A1 (en) 2009-07-15 2011-01-20 N.V. Nutricia Mixture of non-digestible oligosaccharides for stimulating the immune system
CN105510321A (zh) * 2011-12-29 2016-04-20 闫文广 用于上皮组织肿瘤细胞的检测剂组合物及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4321251A (en) * 1979-12-19 1982-03-23 The United States Of America As Represented By The Department Of Health And Human Services Detection of malignant lesions of the oral cavity utilizing toluidine blue rinse
US5194373A (en) * 1985-06-06 1993-03-16 Thomas Jefferson University Method of determining endothelial cell coverage of a prosthetic surface
US4816395A (en) * 1985-12-19 1989-03-28 Peralta Cancer Research Institute Method for predicting chemosensitivity of anti-cancer drugs
CA2097695C (en) * 1991-10-31 2000-08-08 Mark J. Malmros Biological stain composition, method of preparation and method of use for delineation of epithelial cancer
RU2127429C1 (ru) * 1995-06-06 1999-03-10 Эммануил Маркович Коган Способ диагностики гиперпластических процессов и рака эндометрия
EP0814847B1 (de) * 1996-01-16 2003-11-05 Zila, Inc. Verfahren und mittel zur in-vivo erkennung von mundhöhlenkrebs und von präkanzerösen zuständen
US6086852A (en) * 1997-11-13 2000-07-11 Zila, Inc. In vivo stain composition, process of manufacture, and methods of use to identify dysplastic tissue
US6194573B1 (en) * 1997-11-13 2001-02-27 Zila, Inc. Process for manufacture of in vivo stain composition
CN1398189A (zh) * 1998-12-23 2003-02-19 G.D.西尔公司 用于治疗肿瘤形成的放疗与cox－2抑制剂的联合治疗
AU2000237154A1 (en) * 2000-02-28 2001-09-12 Zila, Inc. Method for detecting and killing epithelial cancer cells
CN1374855A (zh) * 2000-07-20 2002-10-16 日拉公司 用于检测发育异常上皮组织的改进诊断方法
EP1322339A4 (de) * 2000-09-26 2004-05-26 Zila Inc METHODE ZUR FRüHEN VORHERSAGE DES AUFTRETENS VON INVASIVEM KREBS.

Also Published As

Publication number Publication date
AU785489B2 (en) 2007-11-15
BR0104747A (pt) 2002-09-17
WO2001064255A1 (en) 2001-09-07
NO20015242D0 (no) 2001-10-26
WO2001064110A1 (en) 2001-09-07
NO20015242L (no) 2001-11-29
CN1365288A (zh) 2002-08-21
KR20080080681A (ko) 2008-09-04
EP1214101A4 (de) 2005-04-13
CA2370741A1 (en) 2001-09-07
KR20020000222A (ko) 2002-01-05
AU4331601A (en) 2001-09-12
MXPA01010886A (es) 2002-05-06
RU2226404C2 (ru) 2004-04-10
JP2003525044A (ja) 2003-08-26
CZ20013861A3 (cs) 2002-08-14
CN100544770C (zh) 2009-09-30
IL146141A0 (en) 2002-07-25
AU2000237154A1 (en) 2001-09-12
EP1214101A1 (de) 2002-06-19
KR100907122B1 (ko) 2009-07-09

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Legal Events

Date Code Title Description
PSEA Patent sealed
RENW Renewal (renewal fees accepted)
ASS Change of ownership

Owner name: ZILA BIOTECHNOLOGY, INC., US

Free format text: OLD OWNER(S): ZILA, INC.

RENW Renewal (renewal fees accepted)