NZ515193A - An autotaxin polypeptide to treat diseases associated with elevated serum glucose lipid or free fatty acid levels - Google Patents

An autotaxin polypeptide to treat diseases associated with elevated serum glucose lipid or free fatty acid levels

Info

Publication number
NZ515193A
NZ515193A NZ515193A NZ51519300A NZ515193A NZ 515193 A NZ515193 A NZ 515193A NZ 515193 A NZ515193 A NZ 515193A NZ 51519300 A NZ51519300 A NZ 51519300A NZ 515193 A NZ515193 A NZ 515193A
Authority
NZ
New Zealand
Prior art keywords
autotaxin
amino acid
seq
polypeptide
acid residues
Prior art date
Application number
NZ515193A
Other languages
English (en)
Inventor
James D Kelly
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of NZ515193A publication Critical patent/NZ515193A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NZ515193A 1999-05-07 2000-05-05 An autotaxin polypeptide to treat diseases associated with elevated serum glucose lipid or free fatty acid levels NZ515193A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30697999A 1999-05-07 1999-05-07
PCT/US2000/012402 WO2000068386A1 (fr) 1999-05-07 2000-05-05 Variantes de l'autotaxine et leurs utilisations dans le traitement des troubles du metabolisme

Publications (1)

Publication Number Publication Date
NZ515193A true NZ515193A (en) 2003-05-30

Family

ID=23187734

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ515193A NZ515193A (en) 1999-05-07 2000-05-05 An autotaxin polypeptide to treat diseases associated with elevated serum glucose lipid or free fatty acid levels

Country Status (7)

Country Link
EP (1) EP1177298A1 (fr)
JP (1) JP2002543789A (fr)
AU (1) AU4825000A (fr)
CA (1) CA2372805A1 (fr)
IL (1) IL146237A0 (fr)
NZ (1) NZ515193A (fr)
WO (1) WO2000068386A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040053893A1 (en) * 2000-12-28 2004-03-18 Tatsuya Kishimoto Method of assaying iysophospholipase d activity
US20050222070A1 (en) 2002-05-29 2005-10-06 Develogen Aktiengesellschaft Fuer Entwicklungsbiologische Forschung Pancreas-specific proteins
AU2002330215A1 (en) * 2001-10-03 2003-04-14 Oxford Glycosciences (Uk) Ltd. Nucleic acid molecules, polypeptides and uses therefor, including diagnosis and treatment of alzheimer's disease
JPWO2003031615A1 (ja) * 2001-10-04 2005-01-27 株式会社アプロサイエンス リゾホスファチジン酸合成酵素阻害物質
JP2005527614A (ja) * 2002-05-29 2005-09-15 デヴェロゲン アクチエンゲゼルシャフト フュア エントヴィックルングスビオローギッシェ フォルシュング 膵臓特異性タンパク質
JP5628477B2 (ja) 2005-06-10 2014-11-19 ティラビスコ アーベー 肥満治療用植物細胞膜の使用
CN106970220A (zh) * 2006-08-03 2017-07-21 国立大学法人东京大学 天然形式人自分泌运动因子特异的抗体、其筛选方法以及检测试剂
JP5864918B2 (ja) * 2011-07-06 2016-02-17 国立大学法人東北大学 オートタキシンアイソフォーム特異的抗体および検出方法
WO2013138241A1 (fr) * 2012-03-15 2013-09-19 Janssen Biotech, Inc. Anticorps dirigés contre l'autotaxine humaine et procédés d'utilisation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5731167A (en) * 1992-01-17 1998-03-24 The United States Of America As Represented By The Department Of Health And Human Services Autotaxin: motility stimulating protein useful in cancer diagnosis and therapy

Also Published As

Publication number Publication date
WO2000068386A1 (fr) 2000-11-16
IL146237A0 (en) 2002-07-25
CA2372805A1 (fr) 2000-11-16
EP1177298A1 (fr) 2002-02-06
JP2002543789A (ja) 2002-12-24
AU4825000A (en) 2000-11-21

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Legal Events

Date Code Title Description
PSEA Patent sealed